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Cited by 47Sperm and Testicular FunctionHeavy Metal Exposure and ToxicityEffects and risks of endocrine disrupting chemicals

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Plin4 exacerbates cadmium-decreased testosterone level via inducing ferroptosis in testicular Leydig cells

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Zhang, Xu-Dong, Sun, Jian, Zheng, Xin-Mei, Zhang, Jin, Tan, Lu-Lu, Fan, Long-Long, Luo, Ye-Xin, Hu, Yi-Fan, Xu, Shen-Dong, Zhou, Huan, Zhang, Yu-Feng, Li, Hao, Yuan, Zhi, Wei, Tian, Zhu, Hua-Long, Xu, De-Xiang, Xiong, Yong-Wei, Wang, Hua·2024·Redox Biology
DOI 10.1016/j.redox.2024.103312PMC PMC11387904
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Abstract

⁺ and testosterone in environmental stress-treated Leydig cells. Collectively, these results suggest that Plin4 exacerbates environmental stress-decreased testosterone level via inducing ferroptosis in testicular Leydig cells.

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Metadata

Authors
Zhang, X.-D., Sun, J., Zheng, X.-M., Zhang, J., Tan, L.-L., Fan, L.-L., Luo, Y.-X., Hu, Y.-F., Xu, S.-D., Zhou, H., Zhang, Y.-F., Li, H., Yuan, Z., Wei, T., Zhu, H.-L., Xu, D.-X., Xiong, Y.-W., & Wang, H.
Affiliations
  • Anhui Medical University (CN)
  • Ministry of Education of the People's Republic of China (CN)
Corresponding author
  • Xiong, Yong-Wei
  • Wang, Hua
ORCID
Venue
Redox Biology
Publisher
Elsevier BV
Published
2024-10
Volume
76
Pages
103312
ISSN
2213-2317 (ISSN-L)
DOI
10.1016/j.redox.2024.103312
PMC
PMC11387904
OpenAlex
W4401660666
Cited by
47
References
4
Citations by year
2026: 23 · 2025: 22 · 2024: 2
FWCI
12.72
Type
journal article
Language
en
Open access
Licence
Locations
  • Redox Biology (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Key Technologies Research and Development Program (2022YFC2702904)
  • National Natural Science Foundation of China (82273664)
  • National Key Research and Development Program of China
  • Anhui Medical University (JKS2022016, 2023xkj008)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Heavy Metal Exposure and Toxicity
  • Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Effects and risks of endocrine disrupting chemicals
Keywords
PLIN4, cadmium, testosterone, ferroptosis, environmental stress, lipid peroxidation, testicular function
MeSH terms
Perilipin-4, Ferroptosis, Adult, Animals, Cadmium, Humans, Iron, Leydig Cells, Male, Mice, Inbred C57BL, Testosterone, Mice, Lipid Droplets

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