Lung imaging in COPD and asthma

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

Hogg, J. C., Chu, F. S. F., Utokaparch, S., Woods, R. R., Elliott, W. M., Buzatu, L., Cherniack, R. M., Rogers, R. M., Sciurba, F. C., Coxson, H. O., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032158 · Cited by 3,756 · see citing works

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

Lange, P., Celli, B., Agustí, A., Boje Jensen, G., Divo, M., Faner, R., Guerra, S., Marott, J. L., Martinez, F. D., Martinez-Camblor, P., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1411532 · Cited by 1,284 · see citing works

THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA

Dunnill, M. S. (1960) · Journal of Clinical Pathology · doi:10.1136/jcp.13.1.27 · Cited by 1,024 · see citing works

Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary

Agustí, A. G. N., Celli, B. R., Criner, G. J., Halpin, D. M. G., Anzueto, A., Barnes, P. J., Bourbeau, J., Han, M. K., Martínez, F. J., de, M. M., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202301-0106pp · Cited by 871 · see citing works

Computed tomography–based biomarker provides unique signature for diagnosis of COPD phenotypes and disease progression

Galbán, C. J., Han, M. K., Boes, J. L., Chughtai, K. A., Meyer, C. R., Johnson, T. D., Galbán, S., Rehemtulla, A., Kazerooni, E. A., Martínez, F. J., et al. (2012) · Nature Medicine · doi:10.1038/nm.2971 · Cited by 819 · see citing works

Computed Tomographic Measurements of Airway Dimensions and Emphysema in Smokers

NAKANO, Y., MURO, S., SAKAI, H., HIRAI, T., CHIN, K., TSUKINO, M., NISHIMURA, K., ITOH, H., PARÉ, P. D., HOGG, J. C., et al. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.162.3.9907120 · Cited by 695 · see citing works

CT-Definable Subtypes of Chronic Obstructive Pulmonary Disease: A Statement of the Fleischner Society

Lynch, D. A., Austin, J. H. M., Hogg, J. C., Greniér, P., Kauczor, H., Bankier, A. A., Barr, R. G., Colby, T. V., Galvin, J. R., Gevenois, P. A., et al. (2015) · Radiology · doi:10.1148/radiol.2015141579 · Cited by 662 · see citing works

Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

Dunican, E. M., Elicker, B. M., Gierada, D. S., Nagle, S. K., Schiebler, M. L., Newell, J. D., Raymond, W. W., Lachowicz-Scroggins, M. E., Maio, S. D., Hoffman, E. A., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci95693 · Cited by 634 · see citing works

Global Initiative for Asthma Strategy 2021: Executive Summary and Rationale for Key Changes

Reddel, H. K., Bacharier, L. B., Bateman, E. D., Brightling, C. E., Brusselle, G. G., Buhl, R., Cruz, A. A., Duijts, L., Drazen, J. M., FitzGerald, J. M., et al. (2021) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202109-2205pp · Cited by 558 · see citing works

Comparison of Computed Density and Microscopic Morphometry in Pulmonary Emphysema

Gevenois, P. A., De Vuyst, P., Maertelaer, V. D., Zanen, J., Jacobovitz, D., Cosio, M. G., & Yernault, J. C. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.1.8680679 · Cited by 537 · see citing works

Pulmonary Arterial Enlargement and Acute Exacerbations of COPD

Wells, J. M., Washko, G. R., Han, M. K., Abbas, N., Nath, H. P., Mamary, A. J., Regan, E. A., Bailey, W. C., Martínez, F. J., Westfall, E., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1203830 · Cited by 502 · see citing works

The Prediction of Small Airway Dimensions Using Computed Tomography

Nakano, Y., Wong, J., de Jong, P. A., Buzatu, L., Nagao, T., Coxson, H. O., Elliott, W. M., Hogg, J. C., & Paré, P. D. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200407-874oc · Cited by 449 · see citing works

Airflow Limitation and Airway Dimensions in Chronic Obstructive Pulmonary Disease

Hasegawa, M., Nasuhara, Y., Onodera, Y., Makita, H., Nagai, K., Fuke, S., Ito, Y., Betsuyaku, T., & Nishimura, M. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200601-037oc · Cited by 410 · see citing works

Association between Functional Small Airway Disease and FEV1 Decline in Chronic Obstructive Pulmonary Disease

Bhatt, S. P., Soler, X., Wang, X., Murray, S., Anzueto, A., Beaty, T. H., Boriek, A. M., Casaburi, R. H., Criner, G. J., Díaz, A. A., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201511-2219oc · Cited by 389 · see citing works

Airway Wall Thickness in Asthma Assessed by Computed Tomography

Niimi, A., Matsumoto, H., Amitani, R., Nakano, Y., Mishima, M., Minakuchi, M., Nishimura, K., Itoh, H., & Izumi, T. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.162.4.9909044 · Cited by 384 · see citing works

Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease

Mishima, M., Hirai, T., Itoh, H., Nakano, Y., Sakai, H., Muro, S., Nishimura, K., Oku, Y., Chin, K., Ohi, M., et al. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.16.8829 · Cited by 353 · see citing works

Variability of maximum expiratory flow-volume curves.

Green, M., Mead, J., & Turner, J. M. (1974) · Journal of Applied Physiology · doi:10.1152/jappl.1974.37.1.67 · Cited by 348 · see citing works

Annual Change in Pulmonary Function and Clinical Phenotype in Chronic Obstructive Pulmonary Disease

Nishimura, M., Makita, H., Nagai, K., Konno, S., Nasuhara, Y., Hasegawa, M., Shimizu, K., Betsuyaku, T., Ito, Y. M., Fuke, S., et al. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201106-0992oc · Cited by 344 · see citing works

The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease

Hogg, J. C., Paré, P. D., & Hackett, T. (2017) · Physiological Reviews · doi:10.1152/physrev.00025.2015 · Cited by 332 · see citing works

Relationships Between Airflow Obstruction and Quantitative CT Measurements of Emphysema, Air Trapping, and Airways in Subjects With and Without Chronic Obstructive Pulmonary Disease

Schroeder, J., McKenzie, A. S., Zach, J. A., Wilson, C. G., Curran‐Everett, D., Stinson, D. S., Newell, J. D., & Lynch, D. A. (2013) · American Journal of Roentgenology · doi:10.2214/ajr.12.10102 · Cited by 330 · see citing works

From GOLD 0 to Pre-COPD

Han, M. K., Agustí, A. G. N., Celli, B. R., Criner, G. J., Halpin, D. M. G., Roche, N., Papi, A. A., Stockley, R. A., Wedzicha, J. A., & Vogelmeier, C. F. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202008-3328pp · Cited by 280 · see citing works

Computed Tomographic Measures of Pulmonary Vascular Morphology in Smokers and Their Clinical Implications

Estépar, R. S. J., Kinney, G. L., Black‐Shinn, J. L., Bowler, R. P., Kindlmann, G., Ross, J. C., Kikinis, R., Han, M. K., Come, C., Díaz, A. A., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201301-0162oc · Cited by 256 · see citing works

Quantitative Computed Tomography Detects Air Trapping due to Asthma

Newman, K. B., Lynch, D. A., Newman, L. S., Ellegood, D., & Newell, J. D. (1994) · CHEST Journal · doi:10.1378/chest.106.1.105 · Cited by 251 · see citing works

The overlap between bronchiectasis and chronic airway diseases: state of the art and future directions

Polverino, E., Dimakou, K., Hurst, J. R., Martínez‐García, M. Á., Miravitlles, M., Paggiaro, P., Shteinberg, M., Aliberti, S., & Chalmers, J. D. (2018) · European Respiratory Journal · doi:10.1183/13993003.00328-2018 · Cited by 243 · see citing works

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study

Kirby, M., Tanabe, N., Tan, W. C., Zhou, G., Obeidat, M., Hague, C. J., Leipsic, J. A., Bourbeau, J., Sin, D. D., Hogg, J. C., et al. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201704-0692oc · Cited by 238 · see citing works

Lung Perfusion with Dual-energy Multidetector-row CT (MDCT)

Pontana, F., Faivre, J., Rémy‐Jardin, M., Flohr, T. G., Schmidt, B. T., Tacelli, N., Pansini, V., & Rémy, J. (2008) · Academic Radiology · doi:10.1016/j.acra.2008.05.018 · Cited by 233 · see citing works

Airway-Occluding Mucus Plugs and Mortality in Patients With Chronic Obstructive Pulmonary Disease

Díaz, A. A., Orejas, J. L., Grumley, S. A., Nath, H. P., Wang, W., Dolliver, W. R., Yen, A., Kligerman, S. J., Jacobs, K. E., Manapragada, P. P., et al. (2023) · JAMA · doi:10.1001/jama.2023.2065 · Cited by 226 · see citing works

CT-based Visual Classification of Emphysema: Association with Mortality in the COPDGene Study

Lynch, D. A., Moore, C. M., Wilson, C. G., Nevrekar, D., Jennermann, T., Humphries, S. M., Austin, J. H. M., Greniér, P., Kauczor, H., Han, M. K., et al. (2018) · Radiology · doi:10.1148/radiol.2018172294 · Cited by 220 · see citing works

Quantitative Computed Tomography Measures of Emphysema and Airway Wall Thickness Are Related to Respiratory Symptoms

Grydeland, T. B., Dirksen, A., Coxson, H. O., Eagan, T., Thorsen, E., Pillai, S. G., Sharma, S., Eide, G. E., Gulsvik, A., & Bakke, P. S. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200907-1008oc · Cited by 216 · see citing works

Mass preserving nonrigid registration of CT lung images using cubic B‐spline

Yin, Y., Hoffman, E. A., & Lin, C. (2009) · Medical Physics · doi:10.1118/1.3193526 · Cited by 206 · see citing works

Hyperpolarized 3 He diffusion MRI and histology in pulmonary emphysema

Woods, J. C., Choong, C. K. C., Yablonskiy, D. A., Bentley, J., Wong, J., Pierce, J. A., Cooper, J. D., Macklem, P. T., Conradi, M. S., & Hogg, J. C. (2006) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21076 · Cited by 206 · see citing works

Association of Dysanapsis With Chronic Obstructive Pulmonary Disease Among Older Adults

Smith, B. M., Kirby, M., Hoffman, E. A., Kronmal, R. A., Aaron, S. D., Allen, N. B., Bertoni, A. G., Coxson, H. O., Cooper, C., Couper, D. J., et al. (2020) · JAMA · doi:10.1001/jama.2020.6918 · Cited by 201 · see citing works

Expanding Applications of Pulmonary MRI in the Clinical Evaluation of Lung Disorders: Fleischner Society Position Paper

Hatabu, H., Ohno, Y., Gefter, W. B., Párraga, G., Madore, B., Lee, K. S., Altes, T. A., Lynch, D. A., Mayo, J. R., Seo, J. B., et al. (2020) · Radiology · doi:10.1148/radiol.2020201138 · Cited by 199 · see citing works

Pulmonary Hypertension and Computed Tomography Measurement of Small Pulmonary Vessels in Severe Emphysema

Matsuoka, S., Washko, G. R., Yamashiro, T., Estépar, R. S. J., Díaz, A. A., Silverman, E. K., Hoffman, E. A., Fessler, H., Criner, G. J., Marchetti, N. T., et al. (2009) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200908-1189oc · Cited by 192 · see citing works

Mucus Plugs and Emphysema in the Pathophysiology of Airflow Obstruction and Hypoxemia in Smokers

Dunican, E. M., Elicker, B. M., Henry, T. S., Gierada, D. S., Schiebler, M. L., Anderson, W. H., Barjaktarević, I., Barr, R. G., Bleecker, E. R., Boucher, R. C., et al. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202006-2248oc · Cited by 192 · see citing works

Impact of Exacerbations on Emphysema Progression in Chronic Obstructive Pulmonary Disease

Tanabe, N., Muro, S., Hirai, T., Oguma, T., Terada, K., Marumo, S., Kinose, D., Ogawa, E., Hoshino, Y., & Mishima, M. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201009-1535oc · Cited by 182 · see citing works

Effect of Matrix Size on the Image Quality of Ultra-high-resolution CT of the Lung

Hata, A., Yanagawa, M., Honda, O., Kikuchi, N., Miyata, T., Tsukagoshi, S., Uranishi, A., & Tomiyama, N. (2018) · Academic Radiology · doi:10.1016/j.acra.2017.11.017 · Cited by 167 · see citing works

Bronchiectasis in COPD patients: more than a comorbidity?

Martínez‐García, M. Á., & Miravitlles, M. (2017) · International Journal of COPD · doi:10.2147/copd.s132961 · Cited by 162 · see citing works

Deep Learning Enables Automatic Classification of Emphysema Pattern at CT

Humphries, S. M., Notary, A. M., Centeno, J. P., Strand, M. J., Crapo, J. D., Silverman, E. K., Lynch, D. A., & For the Genetic Epidemiology of COPD (COPDGene) Investigators (2019) · Radiology · doi:10.1148/radiol.2019191022 · Cited by 160 · see citing works

Mucus Plugs Persist in Asthma, and Changes in Mucus Plugs Associate with Changes in Airflow over Time

Tang, M. C., Elicker, B. M., Henry, T. S., Gierada, D. S., Schiebler, M. L., Huang, B. K., Peters, M. C., Castro, M., Hoffman, E. A., Fain, S. B., et al. (2022) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202110-2265oc · Cited by 160 · see citing works

Effects of CT Section Thickness and Reconstruction Kernel on Emphysema Quantification

Gierada, D. S., Bierhals, A. J., Choong, C. K. C., Bartel, S. T., Ritter, J. H., Das, N. A., Hong, C., Pilgram, T. K., Bae, K. T., Whiting, B. R., et al. (2009) · Academic Radiology · doi:10.1016/j.acra.2009.08.007 · Cited by 147 · see citing works

Early detection of COPD is important for lung cancer surveillance

Sekine, Y., Katsura, H., Koh, E., Hiroshima, K., & Fujisawa, T. (2011) · European Respiratory Journal · doi:10.1183/09031936.00126011 · Cited by 141 · see citing works

Quantifying the Extent of Emphysema:

Gietema, H. A., Müller, N. L., Fauerbach, P. V. N., Sharma, S., Edwards, L. D., Camp, P. G., & Coxson, H. O. (2011) · Academic Radiology · doi:10.1016/j.acra.2011.01.011 · Cited by 134 · see citing works

CT and Functional MRI to Evaluate Airway Mucus in Severe Asthma

Svenningsen, S., Haider, E. A., Boylan, C., Mukherjee, M., Eddy, R. L., Capaldi, D. P. I., Párraga, G., & Nair, P. K. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.02.403 · Cited by 132 · see citing works

Comparison of low attenuation areas on computed tomographic scans between inner and outer segments of the lung in patients with chronic obstructive pulmonary disease: incidence and contribution to lung function

Nakano, Y., Sakai, H., Muro, S., Hirai, T., Oku, Y., Nishimura, K., & Mishima, M. (1999) · Thorax · doi:10.1136/thx.54.5.384 · Cited by 127 · see citing works

Arterial Vascular Pruning, Right Ventricular Size, and Clinical Outcomes in Chronic Obstructive Pulmonary Disease. A Longitudinal Observational Study

Washko, G. R., Nardelli, P., Ash, S. Y., Vegas‐Sánchez‐Ferrero, G., Rahaghi, F. N., Come, C. E., Dransfield, M. T., Kalhan, R., Han, M. K., Bhatt, S. P., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201811-2063oc · Cited by 127 · see citing works

Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD

The COPDGene Investigators, Hersh, C. P., Washko, G. R., Estépar, R. S. J., Lutz, S. M., Friedman, P. J., Han, M. K., Hokanson, J. E., Judy, P. F., Lynch, D. A., et al. (2013) · Respiratory Research · doi:10.1186/1465-9921-14-42 · Cited by 123 · see citing works

Biologics for severe asthma: The real-world evidence, effectiveness of switching, and prediction factors for the efficacy

Nagase, H., Suzukawa, M., Oishi, K., & Matsunaga, K. (2022) · Allergology International · doi:10.1016/j.alit.2022.11.008 · Cited by 117 · see citing works

Tezepelumab and Mucus Plugs in Patients with Moderate-to-Severe Asthma

Nordenmark, L. H., Hellqvist, Å., Emson, C. L., Diver, S. E., Porsbjerg, C. M., Griffiths, J. M., Newell, J. D., Peterson, S., Pawlikowska, B., Parnes, J. R., et al. (2023) · NEJM Evidence · doi:10.1056/evidoa2300135 · Cited by 117 · see citing works

Ultra-High-Resolution Computed Tomography of the Lung: Image Quality of a Prototype Scanner

Kakinuma, R., Moriyama, N., Muramatsu, Y., Gomi, S., Suzuki, M., Nagasawa, H., Kusumoto, M., Aso, T., Muramatsu, Y., Tsuchida, T., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137165 · Cited by 113 · see citing works

Dynamic chest radiography: flat-panel detector (FPD) based functional X-ray imaging

Tanaka, R. (2016) · Radiological Physics and Technology · doi:10.1007/s12194-016-0361-6 · Cited by 113 · see citing works

Effects of Dupilumab on Mucus Plugging and Ventilation Defects in Patients with Moderate-to-Severe Asthma: A Randomized, Double-Blind, Placebo-Controlled Trial

Svenningsen, S., Kjarsgaard, M., Haider, E. A., Venegas, C., Konyer, N. B., Friedlander, Y., Nasir, N., Boylan, C., Kirby, M., & Nair, P. K. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202306-1102le · Cited by 112 · see citing works

Subtyping COPD by Using Visual and Quantitative CT Imaging Features

Park, J., Hobbs, B. D., Crapo, J. D., Make, B. J., Regan, E. A., Humphries, S. M., Carey, V. J., Lynch, D. A., & Silverman, E. K. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.06.015 · Cited by 107 · see citing works

Spatial and temporal heterogeneity of regional lung ventilation determined by electrical impedance tomography during pulmonary function testing

Vogt, B., Pulletz, S., Elke, G., Zhao, Z., Zabel, P., Weiler, N., & Frerichs, I. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01630.2011 · Cited by 103 · see citing works

Luminal Plugging on Chest CT Scan

Okajima, Y., Come, C. E., Nardelli, P., Sonavane, S. K., Yen, A., Nath, H. P., Terry, N. L. J., Grumley, S. A., Ahmed, A., Kligerman, S. J., et al. (2020) · CHEST Journal · doi:10.1016/j.chest.2019.12.046 · Cited by 103 · see citing works

Disease Progression Modeling in Chronic Obstructive Pulmonary Disease

Young, A. L., Bragman, F., Rangelov, B., Han, M. K., Galbán, C. J., Lynch, D. A., Hawkes, D. J., Alexander, D. C., & Hurst, J. R. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201908-1600oc · Cited by 101 · see citing works

Hyperpolarized3He Ventilation Defects Used to Predict Pulmonary Exacerbations in Mild to Moderate Chronic Obstructive Pulmonary Disease

Kirby, M., Pike, D., Coxson, H. O., McCormack, D. G., & Párraga, G. (2014) · Radiology · doi:10.1148/radiol.14140161 · Cited by 99 · see citing works

Effect of short-term treatment with inhaled corticosteroid on airway wall thickening in asthma

Niimi, A., Matsumoto, H., Amitani, R., Nakano, Y., Sakai, H., Takemura, M., Ueda, T., Chin, K., Itoh, H., Ingenito, E. P., et al. (2004) · The American Journal of Medicine · doi:10.1016/j.amjmed.2003.11.026 · Cited by 96 · see citing works

Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study

Tan, W. C., Hague, C. J., Leipsic, J. A., Bourbeau, J., Zheng, L., Li, P. Z., Sin, D. D., Coxson, H. O., Kirby, M., Hogg, J. C., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166745 · Cited by 92 · see citing works

Voxel-Wise Longitudinal Parametric Response Mapping Analysis of Chest Computed Tomography in Smokers

Labaki, W. W., Gu, T., Murray, S., Hatt, C. R., Galbán, C. J., Ross, B. D., Martinez, C. H., Curtis, J. L., Hoffman, E. A., Pompe, E., et al. (2018) · Academic Radiology · doi:10.1016/j.acra.2018.05.024 · Cited by 92 · see citing works

Association Between Expiratory Central Airway Collapse and Respiratory Outcomes Among Smokers

Bhatt, S. P., Terry, N. L. J., Nath, H. P., Zach, J. A., Tschirren, J., Bolding, M., Stinson, D. S., Wilson, C. G., Curran‐Everett, D., Lynch, D. A., et al. (2016) · JAMA · doi:10.1001/jama.2015.19431 · Cited by 90 · see citing works

Regional lung function determined by electrical impedance tomography during bronchodilator reversibility testing in patients with asthma

Frerichs, I., Zhao, Z., Becher, T., Zabel, P., Weiler, N., & Vogt, B. (2016) · Physiological Measurement · doi:10.1088/0967-3334/37/6/698 · Cited by 83 · see citing works

Is Computed Tomography Airway Count Related to Asthma Severity and Airway Structure and Function?

Eddy, R. L., Svenningsen, S., Kirby, M., Knipping, D., McCormack, D. G., Licskai, C. J., Nair, P. K., & Párraga, G. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201908-1552oc · Cited by 83 · see citing works

Computed Tomography Measure of Lung at Risk and Lung Function Decline in Chronic Obstructive Pulmonary Disease

Bhatt, S. P., Bodduluri, S., Hoffman, E. A., Newell, J. D., Sieren, J. C., Dransfield, M. T., & Reinhardt, J. M. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201701-0050oc · Cited by 82 · see citing works

CT Mucus Score and 129Xe MRI Ventilation Defects After 2.5 Years’ Anti-IL-5Rα in Eosinophilic Asthma

McIntosh, M. J., Kooner, H. K., Eddy, R. L., Wilson, A., Serajeddini, H., Bhalla, A., Licskai, C. J., Mackenzie, C. A., Yamashita, C. M., & Párraga, G. (2023) · CHEST Journal · doi:10.1016/j.chest.2023.02.009 · Cited by 81 · see citing works

Selection of patients for lung volume reduction surgery using a power law analysis of the computed tomographic scan

Coxson, H. O. (2003) · Thorax · doi:10.1136/thorax.58.6.510 · Cited by 76 · see citing works

Pruning of the Pulmonary Vasculature in Asthma. The Severe Asthma Research Program (SARP) Cohort

Ash, S. Y., Rahaghi, F. N., Come, C. E., Ross, J. C., Colon, A., Cardet, J. C., Dunican, E. M., Bleecker, E. R., Castro, M., Fahy, J. V., et al. (2018) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201712-2426oc · Cited by 75 · see citing works

Free-breathing Dynamic 19F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD

Gutberlet, M., Kaireit, T. F., Voskrebenzev, A., Lasch, F., Freise, J., Welte, T., Wacker, F. K., Hohlfeld, J. M., & Vogel‐Claussen, J. (2017) · Radiology · doi:10.1148/radiol.2017170591 · Cited by 66 · see citing works

Basics concepts and clinical applications of oxygen-enhanced MR imaging

Ohno, Y., & Hatabu, H. (2007) · European Journal of Radiology · doi:10.1016/j.ejrad.2007.08.006 · Cited by 64 · see citing works

Regional lung response to bronchodilator reversibility testing determined by electrical impedance tomography in chronic obstructive pulmonary disease

Vogt, B., Zhao, Z., Zabel, P., Weiler, N., & Frerichs, I. (2016) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00463.2015 · Cited by 64 · see citing works

Small airway loss in the physiologically ageing lung: a cross-sectional study in unused donor lungs

Verleden, S. E., Kirby, M., Everaerts, S., Vanstapel, A., McDonough, J. E., Verbeken, E. K., Braubach, P., Boone, M., Aslam, D., Verschakelen, J., et al. (2020) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(20)30324-6 · Cited by 64 · see citing works

Quantitative CT metrics are associated with longitudinal lung function decline and future asthma exacerbations: Results from SARP-3

Krings, J. G., Goss, C. W., Lew, D., Samant, M., McGregor, M. C., Boomer, J. S., Bacharier, L. B., Sheshadri, A., Hall, C. S., Brownell, J., et al. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.01.029 · Cited by 64 · see citing works

Airway fractal dimension predicts respiratory morbidity and mortality in COPD

Bodduluri, S., Puliyakote, A. S. K., Gerard, S. E., Reinhardt, J. M., Hoffman, E. A., Newell, J. D., Nath, H. P., Han, M. K., Washko, G. R., Estépar, R. S. J., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci120693 · Cited by 63 · see citing works

The Link between Asthma and Bronchiectasis: State of the Art

Crimi, C., Ferri, S., Campisi, R., & Crimi, N. (2020) · Respiration · doi:10.1159/000507228 · Cited by 63 · see citing works

Imaging of Ventilation with Dual-Energy CT during Breath Hold after Single Vital-Capacity Inspiration of Stable Xenon

Honda, N., Osada, H., Watanabe, W., Nakayama, M., Nishimura, K., Krauß, B., & Otani, K. (2011) · Radiology · doi:10.1148/radiol.11110569 · Cited by 58 · see citing works

Biomechanical CT metrics are associated with patient outcomes in COPD

Bodduluri, S., Bhatt, S. P., Hoffman, E. A., Newell, J. D., Martínez, C. H., Dransfield, M. T., Han, M. K., & Reinhardt, J. M. (2017) · Thorax · doi:10.1136/thoraxjnl-2016-209544 · Cited by 56 · see citing works

Effect of Benralizumab on Mucus Plugs in Severe Eosinophilic Asthma

Sakai, N., Koya, T., Murai, Y., Tsubokawa, F., Tanaka, K., Naramoto, S., Aoki, A., Shima, K., Kimura, Y., Watanabe, S., et al. (2023) · International Archives of Allergy and Immunology · doi:10.1159/000530392 · Cited by 56 · see citing works

Small Airway Disease in Pre-Chronic Obstructive Pulmonary Disease with Emphysema: A Cross-Sectional Study

Verleden, S. E., Hendriks, J. M., Snoeckx, A., Mai, C., Mentens, Y., Callebaut, W., Belie, B. D., Schil, P. E. V., Verplancke, V., Janssens, A., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202301-0132oc · Cited by 56 · see citing works

Quantitative Assessment of Bronchial Wall Attenuation With Thin-Section CT: An Indicator of Airflow Limitation in Chronic Obstructive Pulmonary Disease

Yamashiro, T., Matsuoka, S., Estépar, R. S. J., Dransfield, M. T., Díaz, A. A., Reilly, J. J., Patz, S., Murayama, S., Silverman, E. K., Hatabu, H., et al. (2010) · American Journal of Roentgenology · doi:10.2214/ajr.09.3653 · Cited by 52 · see citing works

A Mixed Phenotype of Airway Wall Thickening and Emphysema Is Associated with Dyspnea and Hospitalization for Chronic Obstructive Pulmonary Disease

Tho, N. V., Ogawa, E., Trang, L. T. H., Ryujin, Y., Kanda, R., Nakagawa, H., Goto, K., Fukunaga, K., Higami, Y., Ruriko, S., et al. (2015) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201411-501oc · Cited by 51 · see citing works

Comparison of airway remodelling assessed by computed tomography in asthma and COPD

Shimizu, K., Hasegawa, M., Makita, H., Nasuhara, Y., Konno, S., & Nishimura, M. (2011) · Respiratory Medicine · doi:10.1016/j.rmed.2011.04.007 · Cited by 51 · see citing works

Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory

Shimizu, K., Tanabe, N., Oguma, A., Kimura, H., Suzuki, M., Yokota, I., Makita, H., Satô, S., Hirai, T., Nishimura, M., et al. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.07.042 · Cited by 48 · see citing works

Management goals and stable phase management of patients with chronic obstructive pulmonary disease in the Japanese respiratory society guideline for the management of chronic obstructive pulmonary disease 2022 (6th edition)

Shibata, Y., Kawayama, T., Muro, S., & Sugiura, H. (2023) · Respiratory Investigation · doi:10.1016/j.resinv.2023.08.007 · Cited by 48 · see citing works

Complexity of Terminal Airspace Geometry Assessed by Computed Tomography in Asthma

Mitsunobu, F., Ashida, K., Hosaki, Y., Tsugeno, H., Okamoto, M., Nishida, K., Takata, S., Yokoi, T., Mishima, M., & Tanizaki, Y. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2112070 · Cited by 46 · see citing works

Emphysema distribution and annual changes in pulmonary function in male patients with chronic obstructive pulmonary disease

Tanabe, N., Muro, S., Tanaka, S., Satô, S., Oguma, T., Kiyokawa, H., Takahashi, T., Kinose, D., Hoshino, Y., Kubo, T., et al. (2012) · Respiratory Research · doi:10.1186/1465-9921-13-31 · Cited by 45 · see citing works

Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans

Angelini, E. D., Yang, J., Balte, P., Hoffman, E. A., Manichaikul, A. W., Sun, Y., Shen, W., Austin, J. H. M., Allen, N. B., Bleecker, E. R., et al. (2023) · Thorax · doi:10.1136/thorax-2022-219158 · Cited by 45 · see citing works

Grading obstructive lung disease using tomographic pulmonary scintigraphy in patients with chronic obstructive pulmonary disease (COPD) and long-term smokers

Bajc, M., Markstad, H., Jarenbäck, L., Tufvesson, E., Bjermer, L. H., & Jögi, J. (2014) · Annals of Nuclear Medicine · doi:10.1007/s12149-014-0913-y · Cited by 44 · see citing works

Association between Emphysema and Chronic Obstructive Pulmonary Disease Outcomes in the COPDGene and SPIROMICS Cohorts: A Post Hoc Analysis of Two Clinical Trials

Han, M. K., Tayob, N., Murray, S., Woodruff, P. G., Curtis, J. L., Kim, V., Criner, G. J., Galbán, C. J., Ross, B. D., Hoffman, E. A., et al. (2018) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201801-0051le · Cited by 44 · see citing works

Computed Tomography Total Airway Count Is Associated with the Number of Micro–Computed Tomography Terminal Bronchioles

Kirby, M., Tanabe, N., Vasilescu, D. M., Cooper, J. D., McDonough, J. E., Verleden, S. E., Vanaudenaerde, B. M., Sin, D. D., Tan, W. C., Coxson, H. O., et al. (2019) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201910-1948le · Cited by 44 · see citing works

Quantitative measurement of airway dimensions using ultra-high resolution computed tomography

Tanabe, N., Oguma, T., Satô, S., Kubo, T., Kozawa, S., Shima, H., Koizumi, K., Sato, A., Muro, S., Togashi, K., et al. (2018) · Respiratory Investigation · doi:10.1016/j.resinv.2018.07.008 · Cited by 43 · see citing works

Pathological Comparisons of Paraseptal and Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease

Tanabe, N., Vasilescu, D. M., Hague, C. J., Ikezoe, K., Murphy, D. T., Kirby, M., Stevenson, C. S., Verleden, S. E., Vanaudenaerde, B. M., Gayan‐Ramirez, G., et al. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201912-2327oc · Cited by 41 · see citing works

Lung Scintigraphy in COPD

Mortensen, J., & Berg, R. M. G. (2018) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2018.10.010 · Cited by 40 · see citing works

Artificial Intelligence–based CT Assessment of Bronchiectasis: The COPDGene Study

Díaz, A. A., Nardelli, P., Wang, W., Estépar, R. S. J., Yen, A., Kligerman, S. J., Maselli, D. J., Dolliver, W. R., Tsao, A., Orejas, J. L., et al. (2022) · Radiology · doi:10.1148/radiol.221109 · Cited by 40 · see citing works

Limitations of Airway Dimension Measurement on Images Obtained Using Multi-Detector Row Computed Tomography

Oguma, T., Hirai, T., Niimi, A., Matsumoto, H., Muro, S., Shigematsu, M., Nishimura, T., Kubo, Y., & Mishima, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076381 · Cited by 39 · see citing works

Evaluation of the Normal Airway Morphology Using Optical Coherence Tomography

Su, Z., Guan, W., Li, S., Feng, J., Zhou, Z., Chen, Y., Zhong, M., & Zhong, N. (2019) · CHEST Journal · doi:10.1016/j.chest.2019.06.009 · Cited by 38 · see citing works

Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma

Huang, B. K., Elicker, B. M., Henry, T. S., Kallianos, K. G., Hahn, L. D., Tang, M. C., Heng, F., McCulloch, C. E., Bhakta, N. R., Majumdar, S., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.174124 · Cited by 38 · see citing works

Continuous quantitative measurement of the proximal airway dimensions and lung density on four-dimensional dynamic-ventilation CT in smokers

Yamashiro, T., Moriya, H., Tsubakimoto, M., Matsuoka, S., & Murayama, S. (2016) · International Journal of COPD · doi:10.2147/copd.s100658 · Cited by 37 · see citing works

Per cent low attenuation volume and fractal dimension of low attenuation clusters on CT predict different long-term outcomes in COPD

Shimizu, K., Tanabe, N., Tho, N. V., Suzuki, M., Makita, H., Satô, S., Muro, S., Mishima, M., Hirai, T., Ogawa, E., et al. (2020) · Thorax · doi:10.1136/thoraxjnl-2019-213525 · Cited by 36 · see citing works

Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease

Uemasu, K., Tanabe, N., Tanimura, K., Hasegawa, K., Mizutani, T., Hamakawa, Y., Satô, S., Ogawa, E., Thomas, M. J., Ikegami, M., et al. (2020) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2019-0377oc · Cited by 36 · see citing works

Computed Tomography–based Airway Surface Area–to-Volume Ratio for Phenotyping Airway Remodeling in Chronic Obstructive Pulmonary Disease

Bodduluri, S., Puliyakote, A. S. K., Nakhmani, A., Charbonnier, J., Reinhardt, J. M., & Bhatt, S. P. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202004-0951oc · Cited by 36 · see citing works

Longitudinal shape irregularity of airway lumen assessed by CT in patients with bronchial asthma and COPD

Oguma, T., Hirai, T., Fukui, M., Tanabe, N., Marumo, S., Nakamura, H., Ito, H., Satô, S., Niimi, A., Ito, I., et al. (2015) · Thorax · doi:10.1136/thoraxjnl-2014-206651 · Cited by 35 · see citing works

Direct evaluation of peripheral airways using ultra-high-resolution CT in chronic obstructive pulmonary disease

Tanabe, N., Shima, H., Satô, S., Oguma, T., Kubo, T., Kozawa, S., Koizumi, K., Sato, A., Togashi, K., & Hirai, T. (2019) · European Journal of Radiology · doi:10.1016/j.ejrad.2019.108687 · Cited by 34 · see citing works

Current advances in pulmonary functional imaging

Nakamura, H., Hirai, T., Kurosawa, H., Hamada, K., Matsunaga, K., Shimizu, K., Konno, S., Muro, S., Fukunaga, K., Nakano, Y., et al. (2023) · Respiratory Investigation · doi:10.1016/j.resinv.2023.09.004 · Cited by 34 · see citing works

Intrathoracic Tracheal Volume and Collapsibility on Inspiratory and End-expiratory CT Scans

Yamashiro, T., Estépar, R. S. J., Matsuoka, S., Bartholmai, B. J., Ross, J. C., Díaz, A. A., Murayama, S., Silverman, E. K., Hatabu, H., & Washko, G. R. (2011) · Academic Radiology · doi:10.1016/j.acra.2010.11.005 · Cited by 33 · see citing works

Pulmonary Imaging Phenotypes of Chronic Obstructive Pulmonary Disease Using Multiparametric Response Maps

MacNeil, J. L., Capaldi, D. P. I., Westcott, A. R., Eddy, R. L., Barker, A. L., McCormack, D. G., Kirby, M., & Párraga, G. (2020) · Radiology · doi:10.1148/radiol.2020191735 · Cited by 32 · see citing works

Characterisation of gas exchange in COPD with dissolved-phase hyperpolarised xenon-129 MRI

Myc, L. A., Qing, K., He, M., Tustison, N. J., Lin, Z., Manichaikul, A. W., Patrie, J. T., Cassani, J., Nunoo-Asare, R., Huang, Y., et al. (2020) · Thorax · doi:10.1136/thoraxjnl-2020-214924 · Cited by 32 · see citing works

Overview of MRI for pulmonary functional imaging

Ohno, Y., Hanamatsu, S., Obama, Y., Ueda, T., Ikeda, H., Hattori, H., Murayama, K., & Toyama, H. (2021) · British Journal of Radiology · doi:10.1259/bjr.20201053 · Cited by 32 · see citing works

Physiological impacts of computed tomography airway dysanapsis, fractal dimension, and branch count in asymptomatic never smokers

Maetani, T., Tanabe, N., Terada, S., Shiraishi, Y., Shima, H., Kaji, S., Sakamoto, R., Oguma, T., Satô, S., Masuda, I., et al. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00385.2022 · Cited by 32 · see citing works

Stronger Associations of Centrilobular Than Paraseptal Emphysema With Longitudinal Changes in Diffusing Capacity and Mortality in COPD

Shiraishi, Y., Tanabe, N., Shimizu, K., Oguma, A., Shima, H., Sakamoto, R., Yamazaki, H., Oguma, T., Sato, A., Suzuki, M., et al. (2023) · CHEST Journal · doi:10.1016/j.chest.2023.01.034 · Cited by 32 · see citing works

Computed tomography mucus plugs and airway tree structure in patients with chronic obstructive pulmonary disease: Associations with airflow limitation, health‐related independence and mortality

Tanabe, N., Shimizu, K., Shima, H., Wakazono, N., Shiraishi, Y., Terada, K., Terada, S., Oguma, T., Sakamoto, R., Suzuki, M., et al. (2024) · Respirology · doi:10.1111/resp.14776 · Cited by 31 · see citing works

CT-derived Biomechanical Metrics Improve Agreement Between Spirometry and Emphysema

Bhatt, S. P., Bodduluri, S., Newell, J. D., Hoffman, E. A., Sieren, J. C., Han, M. K., Dransfield, M. T., & Reinhardt, J. M. (2016) · Academic Radiology · doi:10.1016/j.acra.2016.02.002 · Cited by 30 · see citing works

Saber-sheath trachea as a marker of severe airflow obstruction in chronic obstructive pulmonary disease

Ciccarese, F., Poerio, A., Stagni, S., Attinà, D., Fasano, L., Carbonara, P., Reggiani, M. L. B., & Zompatori, M. (2013) · La radiologia medica · doi:10.1007/s11547-013-0318-3 · Cited by 29 · see citing works

Central airway collapse is related to obesity independent of asthma phenotype

Bhatawadekar, S. A., Peters, U., Walsh, R. R., Daphtary, N., MacLean, E. S., Mori, V., Hodgdon, K., Kinsey, C. M., Kaminsky, D. A., Bates, J. H. T., et al. (2021) · Respirology · doi:10.1111/resp.14005 · Cited by 29 · see citing works

Central airway and peripheral lung structures in airway disease-dominant COPD

Tanabe, N., Shimizu, K., Terada, K., Satô, S., Suzuki, M., Shima, H., Oguma, A., Oguma, T., Konno, S., Nishimura, M., et al. (2021) · ERJ Open Research · doi:10.1183/23120541.00672-2020 · Cited by 29 · see citing works

CT-Assessed Dysanapsis and Airflow Obstruction in Early and Mid Adulthood

Vameghestahbanati, M., Hiura, G. T., Barr, R. G., Sieren, J. C., Smith, B. M., & Hoffman, E. A. (2021) · CHEST Journal · doi:10.1016/j.chest.2021.08.038 · Cited by 27 · see citing works

Difference in the craniocaudal gradient of the maximum pixel value change rate between chronic obstructive pulmonary disease patients and normal subjects using sub-mGy dynamic chest radiography with a flat panel detector system

Yamada, Y., Ueyama, M., Abe, T., Araki, T., Abe, T., Nishino, M., Jinzaki, M., Hatabu, H., & Kudoh, S. (2017) · European Journal of Radiology · doi:10.1016/j.ejrad.2017.04.016 · Cited by 24 · see citing works

Lumen area change (Delta Lumen) between inspiratory and expiratory multidetector computed tomography as a measure of severe outcomes in asthmatic patients

Shim, S. S., Schiebler, M. L., Evans, M. D., Jarjour, N. N., Sorkness, R. L., Denlinger, L. C., Rodriguez, A., Wenzel, S. E., Hoffman, E. A., Lin, C., et al. (2018) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2017.12.1004 · Cited by 24 · see citing works

A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma

Leung, C., Tang, M. C., Huang, B. K., Fain, S. B., Hoffman, E. A., Choi, J., Dunican, E. M., Mauger, D. T., Denlinger, L. C., Jarjour, N. N., et al. (2023) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202305-0802oc · Cited by 24 · see citing works

Chest Dynamic-Ventilatory Digital Radiography in Chronic Obstructive or Restrictive Lung Disease

Ohkura, N., Tanaka, R., Watanabe, S., Hara, J., Abo, M., Nakade, Y., Horii, J., Matsuura, Y., Inoue, D., Takata, M., et al. (2021) · International Journal of COPD · doi:10.2147/copd.s309960 · Cited by 23 · see citing works

Panlobular emphysema is associated with COPD disease severity: A study of emphysema subtype by computed tomography

Wilgus, M. L., Abtin, F. G., Markovic, D., Tashkin, D. P., Phillips, J. E., Buhr, R. G., Flynn, M. J., Dembek, M., Cooper, C. B., & Barjaktarević, I. (2021) · Respiratory Medicine · doi:10.1016/j.rmed.2021.106717 · Cited by 23 · see citing works

Subtyping emphysematous COPD by respiratory volume change distributions on CT

Shima, H., Tanabe, N., Oguma, A., Shimizu, K., Kaji, S., Terada, K., Oguma, T., Kubo, T., Suzuki, M., Makita, H., et al. (2022) · Thorax · doi:10.1136/thoraxjnl-2021-218288 · Cited by 22 · see citing works

Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation

Oguma, A., Shimizu, K., Kimura, H., Tanabe, N., Satô, S., Yokota, I., Sato, M., Matsumoto-Sasaki, M., Abe, Y., Takei, N., et al. (2022) · Allergology International · doi:10.1016/j.alit.2022.10.007 · Cited by 22 · see citing works

Associations of fractional exhaled nitric oxide with airway dimension and mucus plugs on ultra-high-resolution computed tomography in former smokers and nonsmokers with asthma

Hayashi, Y., Tanabe, N., Matsumoto, H., Shimizu, K., Sakamoto, R., Oguma, T., Sunadome, H., Sato, A., Satô, S., & Hirai, T. (2024) · Allergology International · doi:10.1016/j.alit.2024.01.013 · Cited by 22 · see citing works

Effect of Lung Volume on Airway Luminal Area Assessed by Computed Tomography in Chronic Obstructive Pulmonary Disease

Kambara, K., Shimizu, K., Makita, H., Hasegawa, M., Nagai, K., Konno, S., & Nishimura, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090040 · Cited by 21 · see citing works

Peripheral Airway Impairment and Dysanapsis Define Risk of Uncontrolled Asthma in Obese Asthmatic Children

Jung, Y., Jean, T., Morphew, T. L., & Galant, S. P. (2021) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2021.09.029 · Cited by 21 · see citing works

Centrilobular Emphysema Is Associated with Pectoralis Muscle Reduction in Current Smokers without Airflow Limitation

Maetani, T., Tanabe, N., Shiraishi, Y., Shimada, T., Terada, S., Shima, H., Mochizuki, F., Sakamoto, R., Kaji, S., Oguma, T., et al. (2023) · Respiration · doi:10.1159/000529031 · Cited by 21 · see citing works

The prevalence and physiological impacts of centrilobular and paraseptal emphysema on computed tomography in smokers with preserved ratio impaired spirometry

Shiraishi, Y., Shimada, T., Tanabe, N., Terada, K., Sakamoto, R., Maetani, T., Shima, H., Mochizuki, F., Oguma, T., Shimizu, K., et al. (2022) · ERJ Open Research · doi:10.1183/23120541.00063-2022 · Cited by 20 · see citing works

Distorted Trachea in Patients with Chronic Obstructive Pulmonary Disease

Muro, S., Nakano, Y., Sakai, H., Takubo, Y., Oku, Y., Chin, K., Nishimura, K., Hirai, T., Kawakami, K., Nakamura, T., et al. (2000) · Respiration · doi:10.1159/000056293 · Cited by 18 · see citing works

Assessment Of Changes In Regional Xenon-Ventilation, Perfusion, And Ventilation-Perfusion Mismatch Using Dual-Energy Computed Tomography After Pharmacological Treatment In Patients With Chronic Obstructive Pulmonary Disease: Visual And Quantitative Analysis

Hwang, H. J., Lee, S. M., Seo, J. B., Lee, J. S., Kim, N., Kim, C., Oh, S. Y., & Lee, S. W. (2019) · International Journal of COPD · doi:10.2147/copd.s210555 · Cited by 17 · see citing works

Effects of Benralizumab on Three-Dimensional Computed Tomography Analysis in Severe Eosinophilic Asthma

Tsubokawa, F., Koya, T., Murai, Y., Tanaka, K., Tsutsui, Y., Naramoto, S., Sakai, N., Aoki, A., Shima, K., Kimura, Y., et al. (2022) · International Archives of Allergy and Immunology · doi:10.1159/000525846 · Cited by 15 · see citing works

Hyperpolarized 129Xe MRI, 99mTc scintigraphy, and SPECT in lung ventilation imaging: a quantitative comparison

Peiffer, J. D., Altes, T. A., Ruset, I. C., Hersman, F. W., Mugler, J. P., Meyer, C. H., Mata, J., Qing, K., & Thomen, R. P. (2023) · Academic Radiology · doi:10.1016/j.acra.2023.10.038 · Cited by 14 · see citing works

Comparison of hyperpolarized 3He-MRI, CT based parametric response mapping, and mucus scores in asthmatics

Carey, K. J., Hotvedt, P., Mummy, D. G., Lee, K. E., Denlinger, L. C., Schiebler, M. L., Sorkness, R. L., Jarjour, N. N., Hatt, C. R., Galbán, C. J., et al. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1178339 · Cited by 13 · see citing works

Low morphometric complexity of emphysematous lesions predicts survival in chronic obstructive pulmonary disease patients

Hwang, J., Oh, Y., Lee, M., Choi, S., Seo, J. B., Lee, S. M., & Kim, N. (2018) · European Radiology · doi:10.1007/s00330-018-5551-7 · Cited by 12 · see citing works

Evaluation of pulmonary function using single-breath-hold dual-energy computed tomography with xenon

Kyoyama, H., Hirata, Y., Kikuchi, S., Sakai, K., Saito, Y., Mikami, S., Moriyama, G., Yanagita, H., Watanabe, W., Otani, K., et al. (2017) · Medicine · doi:10.1097/md.0000000000005937 · Cited by 11 · see citing works

Lobar distribution of non-emphysematous gas trapping and lung hyperinflation in chronic obstructive pulmonary disease

Shima, H., Tanabe, N., Satô, S., Oguma, T., Kubo, T., Kozawa, S., Koizumi, K., Watanabe, A., Sato, A., Togashi, K., et al. (2020) · Respiratory Investigation · doi:10.1016/j.resinv.2020.01.001 · Cited by 11 · see citing works

Novel Respiratory Impedance-Based Phenotypes Reflect Different Pathophysiologies in Chronic Obstructive Pulmonary Disease Patients

Matsuo, Y., Ogawa, E., Ruriko, S., Ryujin, Y., Kinose, D., Yamaguchi, M., Osawa, M., Nagao, T., Kurosawa, H., & Nakano, Y. (2019) · International Journal of COPD · doi:10.2147/copd.s224902 · Cited by 10 · see citing works

Continuous quantitative measurement of the main bronchial dimensions and lung density in the lateral position by four-dimensional dynamic-ventilation CT in smokers and COPD patients

Nagatani, Y., Hashimoto, M., Nitta, N., Oshio, Y., Yamashiro, T., Sato, S., Tsukagoshi, S., Moriya, H., Kimoto, T., Igarashi, T., et al. (2018) · International Journal of COPD · doi:10.2147/copd.s178836 · Cited by 9 · see citing works

Difference in Local Lung Movement During Tidal Breathing Between COPD Patients and Asthma Patients Assessed by Four-dimensional Dynamic-ventilation CT Scan

Mochizuki, E., Kawai, Y., Morikawa, K., Ito, Y., Kagoo, N., Kubota, T., Ichijo, K., Uehara, M., Harada, M., Matsuura, S., et al. (2020) · International Journal of COPD · doi:10.2147/copd.s273425 · Cited by 9 · see citing works

Expiratory central airway collapse and symptoms in smokers

Tanabe, N., Terada, K., Shima, H., Hamakawa, Y., Shiraishi, Y., Shimizu, K., Sato, A., Oguma, T., Satô, S., & Hirai, T. (2021) · Respiratory Investigation · doi:10.1016/j.resinv.2021.03.005 · Cited by 9 · see citing works

A reference equation for lung volume on computed tomography in Japanese middle-aged and elderly adults

Tanabe, N., Satô, S., Shimada, T., Kaji, S., Shiraishi, Y., Terada, S., Maetani, T., Mochizuki, F., Shimizu, K., Suzuki, M., et al. (2023) · Respiratory Investigation · doi:10.1016/j.resinv.2023.12.004 · Cited by 8 · see citing works

Airway Tree Caliber and Susceptibility to Pollution-associated Emphysema: MESA Air and Lung Studies

Sack, C. S., Wang, M., Knutson, V., Gassett, A. J., Hoffman, E. A., Sheppard, L. A., Barr, R. G., Kaufman, J. D., & Smith, B. M. (2024) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.202307-1248oc · Cited by 6 · see citing works

Centrilobular emphysema and airway dysanapsis: factors associated with low respiratory function in younger smokers

Mochizuki, F., Tanabe, N., Shimada, T., Iijima, H., Sakamoto, R., Shiraishi, Y., Maetani, T., Shimizu, K., Suzuki, M., Chubachi, S., et al. (2024) · ERJ Open Research · doi:10.1183/23120541.00695-2023 · Cited by 6 · see citing works

Predicting the Response to Lung Volume Reduction Surgery Using Scintigraphy

Shigemura, N., Akashi, A., Nakagiri, T., Ohta, M., & Matsuda, H. (2004) · Asian Cardiovascular and Thoracic Annals · doi:10.1177/021849230401200109 · Cited by 4 · see citing works

An index of the fractal characteristic of an airway tree is associated with airflow limitations and future body mass index reduction in COPD patients

Kinose, D., Ogawa, E., Kawashima, S., Matsuo-Kashiwagi, Y., Ruriko, S., Yamazaki, A., Yoshihashi, S., Hirayama, Y., & Nakano, Y. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00461.2019 · Cited by 3 · see citing works

Correction: Longitudinal Study of Spatially Heterogeneous Emphysema Progression in Current Smokers with Chronic Obstructive Pulmonary Disease

Tanabe, N., Muro, S., Satô, S., Tanaka, S., Oguma, T., Kiyokawa, H., Takahashi, T., Kinose, D., Hoshino, Y., Kubo, T., et al. (2012) · PLoS ONE · doi:10.1371/annotation/793db8a1-2d43-45bd-9ad5-8dac83195b15 · Cited by 3 · see citing works

Fractal dimension in CT low attenuation areas is predictive of long-term oxygen therapy initiation in COPD patients: Results from two observational cohort studies

Ibaraki, T., Tomoda, K., Fujioka, N., Sakaguchi, K., Fujita, Y., Yamamoto, Y., Hontsu, S., Yamauchi, M., Yoshikawa, M., Tanabe, N., et al. (2021) · Respiratory Investigation · doi:10.1016/j.resinv.2021.09.001 · Cited by 2 · see citing works

Exploring the pathophysiology of anemia in COPD: Insights from chest CT and longitudinal clinical data

Takizawa, A., Shimada, T., Chubachi, S., Arai, T., Miyakawa, A., Iizuka, H., Otake, S., Sakurai, K., Tanabe, N., Yamada, Y., et al. (2025) · Respiratory Medicine · doi:10.1016/j.rmed.2025.108046 · Cited by 9 · see citing works

Effectiveness of biologics for reducing occlusive mucus plugs in patients with severe asthma: a systematic review

Aegerter, H., Brightling, C. E., Dunican, E. M., Lambrecht, B. N., Lugogo, N. L., Newell, J. D., Porsbjerg, C. M., Svenningsen, S., Clarke, D. L., Lindsley, A., et al. (2026) · Respiratory Research · doi:10.1186/s12931-026-03501-z · Cited by 6 · see citing works

Advancements and applications of hyperpolarized xenon MRI for chronic obstructive pulmonary disease assessment in China

Li, H., Li, H., Zhang, M., Fang, Y., Shen, L., Liu, X., Xiao, S., Zeng, Q., Zhou, Q., Zhao, X., et al. (2025) · British Journal of Radiology · doi:10.1093/bjr/tqaf119 · Cited by 4 · see citing works

Electrical impedance tomography-based temporal signals correlate with quantitative computed tomography-based spatial variables in asthma subjects: a pilot study

Jeong, J., Kim, Y., Lee, S. E., Yeo, H. J., Huh, S., & Choi, S. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1660948 · Cited by 3 · see citing works

Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors

Shimizu, K., Tanabe, N., Kimura, H., Miyata, J., Chubachi, S., Nakamaru, Y., Oguma, A., Wakazono, N., Okada, K., Goudarzi, H., et al. (2025) · Journal of Allergy and Clinical Immunology Global · doi:10.1016/j.jacig.2025.100555 · Cited by 3 · see citing works

Swin-Qwen3: a three-stage vision–language framework for automated radiology report generation with multi-agent verification

Abdaoui, H., Barbaria, S., Al Kuwaiti, A., Raouafi, N., Ben Salah, R., & Boussi Rahmouni, H. (2026) · Frontiers in Radiology · doi:10.3389/fradi.2026.1875905

Superior performance of three-dimensional to two-dimensional convolutional neural network for predicting airflow limitation in patients with chronic obstructive pulmonary disease

Shimizu, K., Sugimori, H., Tanabe, N., Wakazono, N., Ito, Y. M., Makita, H., Satô, S., Nishimura, M., Hirai, T., & Konno, S. (2025) · Respiratory Investigation · doi:10.1016/j.resinv.2025.10.008

Hyperpolarisation techniques

Equbal, A., & Mewis, R. E. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781837679966-00154

Letter to the editor: diaphragmatic MRI and 3D spirometry: potential biomarkers in neuromuscular disorders

Liu, M., & Chen, Y. (2025) · Clinical Radiology · doi:10.1016/j.crad.2025.107210

Abnormalities on chest high-resolution computed tomography in patients with cough-variant asthma

Mao, W., Wang, S., Sun, W., Wang, W., Wang, Z., Pan, Z., & Wang, J. (2026) · BMC Pulmonary Medicine · doi:10.1186/s12890-025-04077-y

TCAR y asma: un puente entre la imagen y el tratamiento personalizado

Gómez, A. R., Ibañez, E. C., Costas, M. P., Pérez, S. P., Díaz, A. C. C., & Añón, M. M. (2026) · Radiología · doi:10.1016/j.rx.2026.501806

Bronchiectasis and asthma: a dangerous liaison?

Gaynitdinova, V. V., Panarina, I. N., & Avdeev, S. N. (2026) · PULMONOLOGIYA · doi:10.18093/0869-0189-2026-36-1-84-94

The Evolving Landscape of COPD Typization

Fantin, A., Castaldo, N., Sartori, G., di Chiara, C., Patrucco, F., Morana, G., Patruno, V., & Crisafulli, E. (2026) · Medicina · doi:10.3390/medicina62030564

A prospective, multicenter cohort study to identify unmet medical needs in Japanese patients with chronic obstructive pulmonary disease: The J-UNMET-COPD study protocol

Fujino, N., Tanabe, N., Asai, K., Chubachi, S., Oishi, K., Matsunaga, K., Fukunaga, K., Hirai, T., & Sugiura, H. (2026) · Respiratory Investigation · doi:10.1016/j.resinv.2026.101409

Clinical relevance of extrapulmonary chest computed tomography findings in COPD and asthma: A narrative review of established evidence in COPD and emerging insights in asthma

Tanabe, N., & Chubachi, S. (2026) · Respiratory Investigation · doi:10.1016/j.resinv.2026.101432

Imagerie du syndrome bronchique

Romdhane, H. B., Hutuca, I., Knani, M., Dognon, E., Ba, S. T., Piver, D., & Brillet, P. (2026) · EMC - Radiologie et imagerie médicale - Cardiovasculaire - Thoracique - Cervicale · doi:10.1016/s1879-8535(25)45241-6

Chest CT imaging toward personalized management of chronic obstructive pulmonary disease, asthma, and bronchiectasis: pulmonologist perspectives

Tanabe, N., & Hirai, T. (2026) · Japanese Journal of Radiology · doi:10.1007/s11604-026-02017-2

Emphysema and airway disease synergistically impair exercise tolerance in smokers: A CT-based study

Maetani, T., Sugitani, T., Tanabe, N., Shiraishi, Y., Hayashi, Y., Oguma, T., Sakamoto, R., Ikeda, K., Oshima, Y., Yoshioka, Y., et al. (2026) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2026.104612

CFM-Net: a cross-feature modulation network for chronic respiratory disease diagnosis using electrical impedance tomography and a flow-volume loop representation

Yu, Y., Ren, J., Li, Z., Huang, Z., Wu, Y., Liu, K., Zhou, T., Chen, B., Yao, J., & Tian, H. (2026) · Measurement · doi:10.1016/j.measurement.2026.122527

Descriptive Process Mining of Pulmonary Clinical Pathways Before and During COVID-19

Murazzano, L., Landa, P., Gartner, J., & Côté, A. (2026) · Big Data and Cognitive Computing · doi:10.3390/bdcc10080266

Beyond Hypersecretion: Mucus Plugs as Structural and Biological Determinants of Airway Obstruction

Gómez, J. P. V., Vidal, J. C. T., Guerrero, V. R. V., Ramirez, J. M. A., Mejia, E. A. G., Palencia, I. A. S., Insignares, J. D. L., & Mendoza‐Torres, E. (2026) · Respiration · doi:10.1159/res/aepag012

Structure-Function Imaging of Asthma: Airway and Ventilation Biomarkers

Barker, A. L., Eddy, R. L., Yaremko, H. L., Kirby, M., & Párraga, G. (2020) · Medical radiology · doi:10.1007/978-3-030-43539-4_9 · Cited by 1 · see citing works

129Xe MRI patterns of lung function in patients with asthma and/or COPD in the NOVELTY study

Marshall, H., Smith, L., Biancardi, A. M., Collier, G. J., Chan, H., Hughes, P. J., Brook, M. L., Astley, J., Munro, R., Rajaram, S., et al. (2023) · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition · doi:10.58530/2022/1167

Assessment of lung function in asthma and COPD using hyperpolarized 129 Xe chemical shift saturation recovery spectroscopy and dissolved‐phase MRI

Qing, K., Mugler, J. P., Altes, T. A., Jiang, Y., Mata, J. F., Miller, G. W., Ruset, I. C., Hersman, F. W., & Ruppert, K. (2014) · NMR in Biomedicine · doi:10.1002/nbm.3179 · Cited by 112 · see citing works

[Method of study of lung function with the use of radioactive xenon in bronchial asthma].

Mp, B., Ashikhmina, I. G., & Mi, M. (1978) · PubMed

A comparison of 129Xe MRI and advanced lung function testing in patients with asthma and /or COPD: The NOVELTY ADPro substudy

Marshall, H., Smith, L., Biancardi, A. M., Collier, G. J., Chan, H., Hughes, P. J., Astley, J., Munro, R., Rajaram, S., Capener, D. A., et al. (2021) · doi:10.1183/13993003.congress-2021.pa1872 · Cited by 2 · see citing works