Natural roles of antimicrobial peptides in microbes, plants and animals

A human gut microbial gene catalogue established by metagenomic sequencing

MetaHIT Consortium, Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K. S., Manichanh, C., Nielsen, T., Pons, N., Levenez, F., et al. (2010) · Nature · doi:10.1038/nature08821 · Cited by 11,624 · see citing works

Antimicrobial peptides of multicellular organisms

Zasloff, M. (2002) · Nature · doi:10.1038/415389a · Cited by 8,457 · see citing works

Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?

Brogden, K. A. (2005) · Nature Reviews Microbiology · doi:10.1038/nrmicro1098 · Cited by 5,829 · see citing works

Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies

Hancock, R. E. W., & Sahl, H. (2006) · Nature Biotechnology · doi:10.1038/nbt1267 · Cited by 4,233 · see citing works

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Lemaître, B., Nicolas, E., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1996) · Cell · doi:10.1016/s0092-8674(00)80172-5 · Cited by 4,027 · see citing works

Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response

Liu, P. T., Stenger, S., Li, H., Wenzel, L., Tan, B. H., Krutzik, S. R., Ochoa, M. T., Schauber, J., Wu, K., Meinken, C., et al. (2006) · Science · doi:10.1126/science.1123933 · Cited by 3,924 · see citing works

The host defense of Drosophila melanogaster.

Lemaître, B., & Hoffmann, J. (2007) · Annual Review of Immunology · doi:10.1146/annurev.immunol.25.022106.141615 · Cited by 3,404 · see citing works

Defensins: antimicrobial peptides of innate immunity

Ganz, T. (2003) · Nature Reviews Immunology · doi:10.1038/nri1180 · Cited by 3,066 · see citing works

Nod2-Dependent Regulation of Innate and Adaptive Immunity in the Intestinal Tract

Kobayashi, K. S., Chamaillard, M., Ogura, Y., Henegariu, O., Inohara, N., Núñez, G., & Flavell, R. A. (2005) · Science · doi:10.1126/science.1104911 · Cited by 1,776 · see citing works

Comparative Metagenomics of Microbial Communities

Tringe, S. G., von Mering, C., Kobayashi, A., Salamov, A. A., Chen, K., Chang, H. W., Podar, M., Short, J. M., Mathur, E. J., Detter, J. C., et al. (2005) · Science · doi:10.1126/science.1107851 · Cited by 1,694 · see citing works

Local dispersal promotes biodiversity in a real-life game of rock–paper–scissors

Kerr, B., Riley, M. A., Feldman, M. W., & Bohannan, B. J. M. (2002) · Nature · doi:10.1038/nature00823 · Cited by 1,593 · see citing works

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

Cadwell, K., Liu, J. Y., Brown, S. L., Miyoshi, H., Loh, J., Lennerz, J. K., Kishi, C., Kc, W., Carrero, J. A., Hunt, S., et al. (2008) · Nature · doi:10.1038/nature07416 · Cited by 1,542 · see citing works

Immune adaptations that maintain homeostasis with the intestinal microbiota

Hooper, L. V., & Macpherson, A. J. (2010) · Nature reviews. Immunology · doi:10.1038/nri2710 · Cited by 1,455 · see citing works

Innate antimicrobial peptide protects the skin from invasive bacterial infection

Nizet, V., Ohtake, T., Lauth, X., Trowbridge, J., Rudisill, J., Dorschner, R. A., Pestonjamasp, V., Piraino, J., Huttner, K., & Gallo, R. L. (2001) · Nature · doi:10.1038/35106587 · Cited by 1,198 · see citing works

Prokaryotic Diversity--Magnitude, Dynamics, and Controlling Factors

Torsvik, V., Øvreås, L., & Thingstad, T. F. (2002) · Science · doi:10.1126/science.1071698 · Cited by 1,196 · see citing works

Enteric defensins are essential regulators of intestinal microbial ecology

Salzman, N. H., Hung, K., Haribhai, D., Chu, H., Karlsson-Sjöberg, J., Amir, E., Teggatz, P., Barman, M., Hayward, M., Eastwood, D., et al. (2010) · Nature Immunology · doi:10.1038/ni.1825 · Cited by 1,156 · see citing works

Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

Wilson, C. L., Ouellette, A. J., Satchell, D. P., Ayabe, T., López-Boado, Y. S., Stratman, J. L., Hultgren, S. J., Matrisian, L. M., & Parks, W. C. (1999) · Science · doi:10.1126/science.286.5437.113 · Cited by 1,076 · see citing works

The co-evolution of host cationic antimicrobial peptides and microbial resistance

Peschel, A., & Sahl, H. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1441 · Cited by 1,052 · see citing works

Are innate immune signaling pathways in plants and animals conserved?

Ausubel, F. (2005) · Nature Immunology · doi:10.1038/ni1253 · Cited by 1,021 · see citing works

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

Vaishnava, S., Behrendt, C. L., Ismail, A. S., Eckmann, L., & Hooper, L. V. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808723105 · Cited by 1,019 · see citing works

Reduced Paneth cell α-defensins in ileal Crohn's disease

Wehkamp, J., Salzman, N. H., Porter, E. M., Nuding, S., Weichenthal, M., Petras, R. E., Shen, B., Schaeffeler, E., Schwab, M. G., Linzmeier, R. M., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505256102 · Cited by 988 · see citing works

Microbial Population Structures in the Deep Marine Biosphere

Huber, J. A., Welch, D. B. M., Morrison, H. G., Huse, S. M., Neal, P. R., Butterfield, D. A., & Sogin, M. L. (2007) · Science · doi:10.1126/science.1146689 · Cited by 887 · see citing works

Plant pathogenesis-related (PR) proteins: A focus on PR peptides

Sels, J., Mathys, J., Coninck, B. D., et al. (2008) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2008.06.011 · Cited by 837 · see citing works

Innate Immune Homeostasis by the Homeobox Gene Caudal and Commensal-Gut Mutualism in Drosophila

Ryu, J.-H., Kim, S.-H., Lee, H.-Y., Bai, J. Y., Nam, Y., Bae, J., Lee, D. G., Shin, S. C., Ha, E.-M., & Lee, W. (2008) · Science · doi:10.1126/science.1149357 · Cited by 832 · see citing works

A Direct Role for Dual Oxidase in Drosophila Gut Immunity

Ha, E.-M., Oh, C.-T., Bae, Y. S., & Lee, W. (2005) · Science · doi:10.1126/science.1117311 · Cited by 824 · see citing works

Staphylococcus aureus Resistance to Human Defensins and Evasion of Neutrophil Killing via the Novel Virulence Factor Mprf Is Based on Modification of Membrane Lipids with l -Lysine

Peschel, A., Jack, R. W., Otto, M. J., Collins, L. V., Staubitz, P., NICHOLSON, G. J., Kalbacher, H., Nieuwenhuizen, W. F., Jung, G., Tarkowski, A., et al. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.193.9.1067 · Cited by 785 · see citing works

The Male Determinant of Self-Incompatibility in Brassica

Schopfer, C. R., Nasrallah, M. E., & Nasrallah, J. B. (1999) · Science · doi:10.1126/science.286.5445.1697 · Cited by 784 · see citing works

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

Salzman, N. H., Ghosh, D., Huttner, K. M., Paterson, Y. Y. W., & Bevins, C. L. (2003) · Nature · doi:10.1038/nature01520 · Cited by 765 · see citing works

Mobility promotes and jeopardizes biodiversity in rock–paper–scissors games

Reichenbach, T., Mobilia, M., & Frey, E. (2007) · Nature · doi:10.1038/nature06095 · Cited by 738 · see citing works

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

Chromek, M., Slamová, Z., Bergman, P., Kovács, L., Podracká, L., Ehrén, I., Hökfelt, T., Gudmundsson, G. H., Gallo, R. L., Agerberth, B., et al. (2006) · Nature Medicine · doi:10.1038/nm1407 · Cited by 652 · see citing works

Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia

Tzou, P., Ohresser, S., Ferrandon, D., Capovilla, M., Reichhart, J., Lemaître, B., Hoffmann, J. A., & Imler, J. (2000) · Immunity · doi:10.1016/s1074-7613(00)00072-8 · Cited by 613 · see citing works

Defensin-like polypeptide LUREs are pollen tube attractants secreted from synergid cells

Okuda, S., Tsutsui, H., SHIINA, K., Sprunck, S., Takeuchi, H., Yui, R., Kasahara, R. D., Hamamura, Y., Mizukami, A. G., Susaki, D., et al. (2009) · Nature · doi:10.1038/nature07882 · Cited by 607 · see citing works

Plant Peptides Govern Terminal Differentiation of Bacteria in Symbiosis

de Velde, W. V., Zehirov, G., Szatmári, Á., Debreczeny, M., Ishihara, H., Kevei, Z., Farkas, A., Mikuláss, K. R., Nagy, A., Tiricz, H., et al. (2010) · Science · doi:10.1126/science.1184057 · Cited by 603 · see citing works

Metagenomic and Small-Subunit rRNA Analyses Reveal the Genetic Diversity of Bacteria, Archaea, Fungi, and Viruses in Soil

Fierer, N., Breitbart, M., Nulton, J., Salamon, P., Lozupone, C., Jones, R. M., Robeson, M. S., Edwards, R. A., Felts, B., Rayhawk, S., et al. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00358-07 · Cited by 564 · see citing works

Antibiotic-mediated antagonism leads to a bacterial game of rock–paper–scissors in vivo

Kirkup, B. C., & Riley, M. A. (2004) · Nature Cell Biology · doi:10.1038/nature02429 · Cited by 561 · see citing works

Recognition of Antimicrobial Peptides by a Bacterial Sensor Kinase

Bader, M. W., Sanowar, S., Daley, M. E., Schneider, A. R., Cho, U., Xu, W., Klevit, R. E., Moual, H. L., & Miller, S. I. (2005) · Cell · doi:10.1016/j.cell.2005.05.030 · Cited by 554 · see citing works

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

Schneider, T., Kruse, T., Wimmer, R., Wiedemann, I., Sass, V., Pag, U., Jansen, A., Nielsen, A. K., Mygind, P. H., Raventós, D., et al. (2010) · Science · doi:10.1126/science.1185723 · Cited by 549 · see citing works

Alternative mechanisms of action of cationic antimicrobial peptides on bacteria

Hale, J. D. F., & Hancock, R. E. W. (2007) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.5.6.951 · Cited by 547 · see citing works

A Salmonella Locus that Controls Resistance to Microbicidal Proteins from Phagocytic Cells

Fields, P. I., Groisman, E. A., & Heffron, F. (1989) · Science · doi:10.1126/science.2646710 · Cited by 540 · see citing works

Relish, a Central Factor in the Control of Humoral but Not Cellular Immunity in Drosophila

Hedengren-Olcott, M., BengtÅsling, Dushay, M. S., Andó, I., Ekengren, S. K., Wihlborg, M., & Hultmark, D. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80392-5 · Cited by 540 · see citing works

Chemical warfare between microbes promotes biodiversity

Czárán, T., Hoekstra, R. F., & Pagie, L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.012399899 · Cited by 536 · see citing works

An Alternative Bactericidal Mechanism of Action for Lantibiotic Peptides That Target Lipid II

Hasper, H. E., Kramer, N. E., Smith, L., Hillman, J. D., Zachariah, C., Kuipers, O. P., KRUIJFF, B. D., & Breukink, E. J. (2006) · Science · doi:10.1126/science.1129818 · Cited by 502 · see citing works

Eukaryotic control on bacterial cell cycle and differentiation in the Rhizobium –legume symbiosis

Mergaert, P., Uchiumi, T., Alunni, B., Evanno, G., Cheron, A., Catrice, O., Mausset, A.-E., Barloy-Hubler, F., Galibert, F., Kondorosi, Á., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600912103 · Cited by 501 · see citing works

Discovery of five conserved β-defensin gene clusters using a computational search strategy

Schutte, B. C., Mitros, J., Bartlett, J. A., Walters, J. D., Jia, H. P., Welsh, M. J., Casavant, T. L., & McCray, P. B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042692699 · Cited by 488 · see citing works

Stomagen positively regulates stomatal density in Arabidopsis

Sugano, S. S., Shimada, T., Imai, Y., Okawa, K., Tamai, A., Mori, M., & Hara‐Nishimura, I. (2009) · Nature · doi:10.1038/nature08682 · Cited by 477 · see citing works

Fungal pathogen protection in potato by expression of a plant defensin peptide

Gao, A.-G., Hakimi, S. M., Mittanck, C. A., Wu, Y., Woerner, B. M., Stark, D. M., Shah, D. M., Liang, J., & Rommens, C. M. T. (2000) · Nature Biotechnology · doi:10.1038/82436 · Cited by 472 · see citing works

Small cysteine‐rich peptides resembling antimicrobial peptides have been under‐predicted in plants

Silverstein, K. A. T., Moskal, W. A., Wu, H. C., Underwood, B. A., Graham, M. A., Town, C. D., & VandenBosch, K. A. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03136.x · Cited by 470 · see citing works

A Novel Family in Medicago truncatula Consisting of More Than 300 Nodule-Specific Genes Coding for Small, Secreted Polypeptides with Conserved Cysteine Motifs,

Mergaert, P., Nikovics, K., Kelemen, Z., Maunoury, N., Vaubert, D., Kondorosi, Á., & Kondorosi, É. (2003) · PLANT PHYSIOLOGY · doi:10.1104/pp.102.018192 · Cited by 402 · see citing works

The ecological role of bacteriocins in bacterial competition

Riley, M. A., Riley, M. A., & Gordon, D. M. (1999) · Trends in Microbiology · doi:10.1016/s0966-842x(99)01459-6 · Cited by 388 · see citing works

Experimental evolution of resistance to an antimicrobial peptide

Perron, G. G., ZASLOFF, M. A., & Bell, G. (2005) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2005.3301 · Cited by 371 · see citing works

Antimicrobial Defense and Persistent Infection in Insects

Haine, E. R., Moret, Y., Siva‐Jothy, M. T., & Rolff, J. (2008) · Science · doi:10.1126/science.1165265 · Cited by 328 · see citing works

Improved outcome in shigellosis associated with butyrate induction of an endogenous peptide antibiotic

Raqib, R., Sarker, P., Bergman, P., Ara, G., Lindh, M., Sack, D. A., Islam, K., Gudmundsson, G. H., Andersson, J., & Agerberth, B. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602888103 · Cited by 317 · see citing works

Augmentation of Innate Host Defense by Expression of a Cathelicidin Antimicrobial Peptide

Bals, R., Weiner, D. J., Moscioni, A. D., Meegalla, R. L., & Wilson, J. M. (1999) · Infection and Immunity · doi:10.1128/iai.67.11.6084-6089.1999 · Cited by 302 · see citing works

Gram-positive three-component antimicrobial peptide-sensing system

Li, M., Lai, Y., Villaruz, A. E., Cha, D. J., Sturdevant, D. E., & Otto, M. J. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702159104 · Cited by 288 · see citing works

The Paneth Cell α-Defensin Deficiency of Ileal Crohn’s Disease Is Linked to Wnt/Tcf-4

Wehkamp, J., Wang, G., Kübler, I., Nuding, S., Gregorieff, A., Schnabel, A., Kays, R. J., Fellermann, K., Burk, O., Schwab, M. G., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.5.3109 · Cited by 286 · see citing works

Prevalence of Local Immune Response against Oral Infection in a Drosophila/Pseudomonas Infection Model

Liehl, P., Blight, M. A., Vodovar, N., et al. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020056 · Cited by 269 · see citing works

Human β-Defensin 3 Inhibits Cell Wall Biosynthesis in Staphylococci

Sass, V., Schneider, T., Wilmes, M., Körner, C., Tossi, A., Novikova, N. S., Валерьевна, Ш. О., & Sahl, H. (2010) · Infection and Immunity · doi:10.1128/iai.00688-09 · Cited by 254 · see citing works

Role of the Escherichia coli SbmA in the antimicrobial activity of proline‐rich peptides

Mattiuzzo, M., Bandiera, A., Gennaro, R., Benincasa, M., Pacor, S., Antcheva, N., & Scocchi, M. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2007.05903.x · Cited by 244 · see citing works

Interplay between antibacterial effectors: A macrophage antimicrobial peptide impairs intracellular Salmonella replication

Rosenberger, C. M., Gallo, R. L., & Finlay, B. B. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0304455101 · Cited by 240 · see citing works

Defensin-Like ZmES4 Mediates Pollen Tube Burst in Maize via Opening of the Potassium Channel KZM1

Amien, S., Kliwer, I., Márton, M. L., Debener, T., Geiger, D., Becker, D., & Dresselhaus, T. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000388 · Cited by 236 · see citing works

β-Defensin 1 Contributes to Pulmonary Innate Immunity in Mice

Moser, C., Weiner, D. J., Lysenko, E., Bals, R., Weiser, J. N., & Wilson, J. M. (2002) · Infection and Immunity · doi:10.1128/iai.70.6.3068-3072.2002 · Cited by 213 · see citing works

Characterization of the Mouse Beta Defensin 1, Defb1 , Mutant Mouse Model

Morrison, G. M., Kilanowski, F. M., Davidson, D. J., & Dorin, J. R. (2002) · Infection and Immunity · doi:10.1128/iai.70.6.3053-3060.2002 · Cited by 209 · see citing works

Constitutive expression of a single antimicrobial peptide can restore wild-type resistance to infection in immunodeficient Drosophila mutants

Tzou, P., Reichhart, J., & Lemaître, B. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042411999 · Cited by 204 · see citing works

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

Peyrin‐Biroulet, L., Beisner, J., Wang, G., Nuding, S., Oommen, S. T., Kelly, D., Parmentier-Decrucq, E., Dessein, R., Mérour, E., Chavatte, P., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905745107 · Cited by 199 · see citing works

M1 Protein Allows Group A Streptococcal Survival in Phagocyte Extracellular Traps through Cathelicidin Inhibition

Lauth, X., von Köckritz‐Blickwede, M., McNamara, C. W., Myskowski, S. M., Zinkernagel, A. S., Beall, B., Ghosh, P., Gallo, R. L., & Nizet, V. (2009) · Journal of Innate Immunity · doi:10.1159/000203645 · Cited by 182 · see citing works

An essential complementary role of NF‐κB pathway to microbicidal oxidants in Drosophila gut immunity

Ryu, J.-H., Ha, E.-M., Oh, C.-T., Seol, J.-H., Brey, P. T., Jin, I., Lee, D. G., Kim, J., Lee, D., & Lee, W. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601233 · Cited by 172 · see citing works

Antifungal Pisum sativum Defensin 1 Interacts with Neurospora crassa Cyclin F Related to the Cell Cycle

Lobo, D. S., Pereira, I. B., Madeira, L. F., de Medeiros, L. N., Cabral, L. M., Faria, J., Bellio, M., Campos, R. C., Linden, R., & Kurtenbach, E. (2007) · Biochemistry · doi:10.1021/bi061441j · Cited by 165 · see citing works

Genomic Organization and Evolutionary Insights on GRP and NCR Genes, Two Large Nodule-Specific Gene Families in Medicago truncatula

Alunni, B., Kevei, Z., Redondo‐Nieto, M., et al. (2007) · Molecular Plant-Microbe Interactions · doi:10.1094/mpmi-20-9-1138 · Cited by 139 · see citing works

Induction of group A Streptococcus virulence by a human antimicrobial peptide

Gryllos, I., Tran-Winkler, H. J., Cheng, M., Chung, H., Bolcome, R. E., Lu, W., Lehrer, R. I., & Wessels, M. R. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0803815105 · Cited by 139 · see citing works

Comparing Symbiotic Efficiency between Swollen versus Nonswollen Rhizobial Bacteroids

Oono, R., & Denison, R. F. (2010) · PLANT PHYSIOLOGY · doi:10.1104/pp.110.163436 · Cited by 138 · see citing works

Arming the enemy: the evolution of resistance to self-proteins

Bell, G., & Gouyon, P. (2003) · Microbiology · doi:10.1099/mic.0.26265-0 · Cited by 136 · see citing works

M Protein and Hyaluronic Acid Capsule Are Essential for In Vivo Selection of covRS Mutations Characteristic of Invasive Serotype M1T1 Group A Streptococcus

Cole, J. N., Pence, M. A., von Köckritz‐Blickwede, M., Hollands, A., Gallo, R. L., Walker, M. J., & Nizet, V. (2010) · mBio · doi:10.1128/mbio.00191-10 · Cited by 134 · see citing works

<i>Mycobacterium tuberculosis</i> Cells Growing in Macrophages Are Filamentous and Deficient in FtsZ Rings

Chauhan, A., Madiraju, M. V. V. S., Fol, M., Lofton, H., Maloney, E., Reynolds, R., & Rajagopalan, M. (2006) · Journal of Bacteriology · doi:10.1128/jb.188.5.1856-1865.2006 · Cited by 132 · see citing works

A defensin from tomato with dual function in defense and development

Stotz, H. U., Spence, B., & Wang, Y. (2009) · Plant Molecular Biology · doi:10.1007/s11103-009-9512-z · Cited by 126 · see citing works

MprF-Mediated Lysinylation of Phospholipids in Staphylococcus aureus Leads to Protection against Oxygen-Independent Neutrophil Killing

Kristian, S. A., Dürr, M. C., van Strijp, J. A. G., Neumeister, B., & Peschel, A. (2002) · Infection and Immunity · doi:10.1128/iai.71.1.546-549.2003 · Cited by 122 · see citing works

Peptide inhibitor of cytokinesis during sporulation in Bacillus subtilis

Handler, A. A., Lim, J. E., & Losick, R. M. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06173.x · Cited by 116 · see citing works

Peptide Signaling in Pollen-Pistil Interactions

Higashiyama, T. (2010) · Plant and Cell Physiology · doi:10.1093/pcp/pcq008 · Cited by 116 · see citing works

Antagonistic interactions amongst bacteriocin-producing enteric bacteria in dual species biofilms

Tait, K., & Sutherland, I. W. (2002) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2002.01692.x · Cited by 107 · see citing works

The PhoP-PhoQ Two-Component Regulatory System of Photorhabdus luminescens Is Essential for Virulence in Insects

Derzelle, S., Turlin, É., Duchaud, É., Pagès, S., Kunst, F., Givaudan, A., & Danchin, A. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.5.1270-1279.2004 · Cited by 101 · see citing works

Essential Role for the BacA Protein in the Uptake of a Truncated Eukaryotic Peptide in Sinorhizobium meliloti

Marlow, V. L., Haag, A. F., Kobayashi, H., et al. (2008) · Journal of Bacteriology · doi:10.1128/jb.01661-08 · Cited by 85 · see citing works

Neuroendocrine Nicotinic Receptor Activation Increases Susceptibility to Bacterial Infections by Suppressing Antimicrobial Peptide Production

Radek, K. A., Elias, P. M., Taupenot, L., Mahata, S. K., O’Connor, D. T., & Gallo, R. L. (2010) · Cell Host & Microbe · doi:10.1016/j.chom.2010.03.009 · Cited by 81 · see citing works

Temporal changes in the frequency of colicinogeny in Escherichia coli from house mice

Gordon, D., Riley, M. A., & Pinou, T. (1998) · Microbiology · doi:10.1099/00221287-144-8-2233 · Cited by 79 · see citing works

Short Cationic Antimicrobial Peptides Interact with ATP

Hilpert, K., McLeod, B. N., Yu, J. Z., et al. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01664-09 · Cited by 79 · see citing works

Paneth cells—guardians of the gut cell hatchery

Ganz, T. (2000) · Nature Immunology · doi:10.1038/77884 · Cited by 71 · see citing works

Arabidopsis thaliana plant defensin AtPDF1.1 is involved in the plant response to biotic stress

Coninck, B. D., Sels, J., Venmans, E., et al. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03326.x · Cited by 70 · see citing works

The Erwinia chrysanthemi phoP‐phoQ operon plays an important role in growth at low pH, virulence and bacterial survival in plant tissue

Llama‐Palacios, A., López‐Solanilla, E., Poza‐Carrión, C., et al. (2003) · Molecular Microbiology · doi:10.1046/j.1365-2958.2003.03583.x · Cited by 56 · see citing works

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome

Amid, C., Rehaume, L. M., Brown, K. L., Gilbert, J. G. R., Dougan, G., Hancock, R. E. W., & Harrow, J. (2009) · BMC Genomics · doi:10.1186/1471-2164-10-606 · Cited by 46 · see citing works

Streptococcus pyogenesCovRS Mediates Growth in Iron Starvation and in the Presence of the Human Cationic Antimicrobial Peptide LL-37

Froehlich, B. J., Bates, C. S., & Scott, J. R. (2008) · Journal of Bacteriology · doi:10.1128/jb.01256-08 · Cited by 45 · see citing works

RAMP resistance

Buckling, A., & Brockhurst, M. A. (2005) · Nature · doi:10.1038/438170a · Cited by 11 · see citing works

Antimicrobial peptides from fruits and their potential use as biotechnological tools—a review and outlook

Meneguetti, B. T., Machado, L. D. S., Oshiro, K. G. N., Nogueira, M. L., Carvalho, C. M. E., & Franco, O. L. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.02136 · Cited by 77 · see citing works

Antimicrobial Peptides and Ectosymbiotic Relationships: Involvement of a Novel Type IIa Crustin in the Life Cycle of a Deep-Sea Vent Shrimp

Le Bloa, S., Boidin-Wichlacz, C., Cueff-Gauchard, V., Rosa, R. D., Cuvillier-Hot, V., Durand, L., Methou, P., Pradillon, F., Cambon-Bonavita, M.-A., & Tasiemski, A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01511 · Cited by 30 · see citing works

Antimicrobial Peptides as Mediators of Innate Immunity in Teleosts

Katzenback, B. A. (2015) · Biology · doi:10.3390/biology4040607 · Cited by 166 · see citing works

Antimicrobial Peptides in Innate Immune Responses

Sørensen, O. E., Borregaard, N., & Cole, A. M. (2008) · KARGER eBooks · doi:10.1159/000136315 · Cited by 96 · see citing works

The Pharmacology of Radiolabeled Cationic Antimicrobial Peptides

Brouwer, C. P. J. M., Wulferink, M., & Welling, M. M. (2007) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.21034 · Cited by 27 · see citing works

Antimicrobial Peptides of Animal Origin:Current Situation and Prospect

Wang, Y. (2014) · Dongwu yingyang xuebao · Cited by 2 · see citing works

Antimicrobial activity of surface attached marine bacteria in biofilms

Wilson, G. S., Raftos, D. A., & Nair, S. V. (2010) · Microbiological Research · doi:10.1016/j.micres.2010.08.003 · Cited by 30 · see citing works