The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.
A randomized controlled trial of cognitive behavioral therapy for anxiety and depression in COPD
Open accessAbstract
Background Previous research indicates a high prevalence of untreated anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). The current study examined the effect of cognitive behavioral therapy (CBT) in groups for co-morbid, clinically significant anxiety and depression in COPD outpatients of both sexes.Methods In a randomized, controlled trial, CBT (n = 25) was compared with enhanced standard care (n = 26). Participants in both conditions were followed up at 2 and 8 months from baseline. Main outcome measures comprised the Beck Anxiety Inventory and the Beck Depression Inventory-II. Measures of health status and sleep were included as secondary outcomes. The effects of sex and age were also investigated.Results CBT resulted in improvement in symptoms of anxiety and depression, with effect sizes of 1.1 and 0.9 at post-treatment, respectively. The improvement was maintained at the 8-month follow-up, with effect sizes of 1.4 and 0.9. In the control group, there was no significant change. Compared to men, women had higher symptom levels throughout the whole study period. Younger patients had more anxiety and depression, age had also differential effects in the two groups on change in depressive symptoms. Changes in sleep and health status were small in both groups.Conclusions The findings indicate that CBT may provide rapid symptom relief for COPD patients with clinically significant anxiety and depression, and underline the need for integrating mental health care into the overall medical regimen for COPD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Subtotal *** 143 146 100% -0.3[-1.03,0.44]Heterogeneity: Tau =0.24; Chi =5.68, df=1(P=0.02);I =82.39%Test for overall effect: Z=0.79(P=0.43)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Allocation concealment (selection bias) Low risk Allocation concealment was implemented using numbered containers that were identical in appearance for the two groups”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Subtotal *** 143 146 100% -0.3[-0.73,0.13]Heterogeneity: Tau =0.06; Chi =2.14, df=1(P=0.14);I =53.22%Test for overall effect: Z=1.37(P=0.17)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Random sequence generation (selection bias) Unclear risk Randomisation reported however methods not described”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Subtotal *** 157 162 100% -3.86[-6.63,-1.1]Heterogeneity: Tau =1.16; Chi =2.47, df=2(P=0.29);I =19.09%Test for overall effect: Z=2.74(P=0.01)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Subtotal *** 143 146 100% -0.4[-0.88,0.08]Heterogeneity: Tau =0.08; Chi =2.56, df=1(P=0.11);I =60.97%Test for overall effect: Z=1.63(P=0.1)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Subtotal *** 143 146 100% -0.17[-0.93,0.6]Heterogeneity: Tau =0.26; Chi =6.25, df=1(P=0.01);I =84% Test for overall effect: Z=0.42(P=0.67)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Total *** 157 162 100% -4.41[-8.28,-0.53]Heterogeneity: Tau =7.21; Chi =5.2, df=2(P=0.07);I =61.51%Test for overall effect: Z=2.23(P=0.03)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Subtotal *** 143 146 100% -4.3[-10.57,1.97]Heterogeneity: Tau =16.37;Chi =4.92, df=1(P=0.03);I =79.66%Test for overall effect: Z=1.34(P=0.18)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Blinding of outcome assessment (detection bias) All outcomes Unclear risk No mention of blinding for outcome assessors”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Blinding of participants and personnel (performance bias) All outcomes High risk Neither participants nor therapists were blinded to the intervention”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Other bias Low risk No other biases identified”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Selective reporting (reporting bias) Low risk Prespecified protocol available and no selective reporting identified”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“Incomplete outcome data (attrition bias) All outcomes Low risk Reasons for attrition reported in participant flow chart.Missing outcome data at one measurement point did not preclude analysis as mixed models with random effect was used for analysis; Intention-to-treat analysis occurred”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
In the citing paper
“the target sample size identified as being necessary in the power analysis (33 in each arm) was not reached by the end of the study period (25 in the intervention arm and 26 in the control arm)”
From Psychological therapies for the treatment of anxiety disorders in chronic obstructive pulmonary disease (2017) · cites this paper as Hynninen 2010
Citations
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,603
Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975) · Journal of Psychiatric Research · doi:10.1016/0022-3956(75)90026-6 · Cited by 88,282
Statistical power analysis for the behavioral sciences
Cohen, J. (1990) · Computers Environment and Urban Systems · doi:10.1016/0198-9715(90)90050-4 · Cited by 65,417
Statistical Power Analysis for the Behavioral Sciences (2nd ed.).
Lachenbruch, P. A., & Cohen, J. (1989) · Journal of the American Statistical Association · doi:10.2307/2290095 · Cited by 37,421
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
Jones, P. W., Quirk, F. H., Baveystock, C. M., & Littlejohns, P. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/145.6.1321 · Cited by 3,035
Assessment of client/patient satisfaction: development of a general scale
Larsen, D. L., Attkisson, C. C., Hargreaves, W. A., & Nguyen, T. D. (1979) · Evaluation and Program Planning · doi:10.1016/0149-7189(79)90094-6 · Cited by 2,887 · cited 1×
“The Client Satisfaction Questionnaire (CSQ) was used to assess participants’ satisfaction with treatment.(29) Scores range from 8 to 32, higher scores indicating more satisfaction with the treatment.”
MethodThe St George's Respiratory Questionnaire
Jones, P., Quirk, F. H., & Baveystock, C. M. (1991) · Respiratory Medicine · doi:10.1016/s0954-6111(06)80166-6 · Cited by 2,729
Behavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial
Morin, C. M., Colecchi, C., Stone, J., Sood, R., & Brink, D. (1999) · JAMA · doi:10.1001/jama.281.11.991 · Cited by 1,095
Anxiety and Depression in COPD
Maurer, J., Rebbapragada, V., Borson, S., Goldstein, R., Kunik, M. E., Yohannes, A. M., & Hanania, N. A. (2008) · Chest · doi:10.1378/chest.08-0342 · Cited by 720
Surprisingly High Prevalence of Anxiety and Depression in Chronic Breathing Disorders
Kunik, M. E., Roundy, K., Veazey, C. H., Souchek, J., Richardson, P. A., Wray, N. P., & Stanley, M. A. (2005) · CHEST Journal · doi:10.1378/chest.127.4.1205 · Cited by 658
Collins, L. M. (2006) · Annual Review of Psychology · doi:10.1146/annurev.psych.57.102904.190146 · Cited by 565
(2013) · European Respiratory Society eBooks · doi:10.1183/9781849840415.ch17 · Cited by 507
Ries, A. L., Carlin, B. W., Carrieri‐Kohlman, V., Casaburi, R. H., Celli, B. R., Emery, C. F., Hodgkin, J. E., Mahler, D. A., Make, B. J., & Skolnick, J. L. (1997) · CHEST Journal · doi:10.1378/chest.112.5.1363 · Cited by 499
DSTAT : software for the meta-analytic review of research literatures
Johnson, B. T. (1989) · Medical Entomology and Zoology · Cited by 489
Anxiety and depression in COPD patients: the roles of gender and disease severity
Di Marco, F., Verga, M., Reggente, M., Maria Casanova, F., Santus, P., Blasi, F., Allegra, L., & Centanni, S. (2006) · Respiratory Medicine · doi:10.1016/j.rmed.2006.01.026 · Cited by 474
Sex Differences in Severe Pulmonary Emphysema
Martinez, F. J., Curtis, J. L., Sciurba, F., Mumford, J., Giardino, N. D., Weinmann, G., Kazerooni, E., Murray, S., Criner, G. J., Sin, D. D., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200606-828oc · Cited by 365
Emery, C. F., Schein, R. L., Hauck, E. R., & MacIntyre, N. R. (1998) · Health Psychology · doi:10.1037//0278-6133.17.3.232 · Cited by 353
Emery, C. F., Schein, R. L., Hauck, E. R., & MacIntyre, N. R. (1998) · Health Psychology · doi:10.1037/0278-6133.17.3.232 · Cited by 353 · cited 1×
“Two RCTs demonstrated significant reductions of anxiety or depression.(12,13) However, these studies examined the effect of CBT in combination with exercise training and education.”
BackgroundAnxiety and depression in end-stage COPD
Hill, K., Geist, R., Goldstein, R. S., & Lacasse, Y. (2008) · European Respiratory Journal · doi:10.1183/09031936.00125707 · Cited by 277
Gudmundsson, G., Gislason, T., Janson, C., Lindberg, E., Suppli Ulrik, C., Brøndum, E., Nieminen, M. M., Aine, T., Hallin, R., & Bakke, P. (2006) · Respiratory Medicine · doi:10.1016/j.rmed.2005.04.003 · Cited by 238
Self-citationGillis, M. M., Haaga, D. A. F., & Ford, G. T. (1995) · Psychological Assessment · doi:10.1037/1040-3590.7.4.450 · Cited by 236
Kunik, M. E., Veazey, C., Cully, J. A., Souchek, J., Graham, D. P., Hopko, D., Carter, R., Sharafkhaneh, A., Goepfert, E. J., Wray, N., et al. (2008) · Psychological Medicine · doi:10.1017/s0033291707001687 · Cited by 214
Coventry, P. A., & Hind, D. (2007) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2007.08.002 · Cited by 197
Cleland, J., Lee, A. J., & Hall, S. (2007) · Family Practice · doi:10.1093/fampra/cmm009 · Cited by 176
de Godoy, D. V., & de Godoy, R. F. (2003) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/s0003-9993(03)00239-9 · Cited by 171
Assessing clinical significance: Application to the beck depression inventory
Seggar, L. B., Lambert, M. J., & Hansen, N. B. (2002) · Behavior Therapy · doi:10.1016/s0005-7894(02)80028-4 · Cited by 162
Yohannes, A. M., Connolly, M. J., & Baldwin, R. C. (2001) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.461 · Cited by 124 · cited 3×
“Although pharmacotherapy has been recommended as a treatment strategy for anxiety and depression in this patient group,(8) significant obstacles implementing such interventions have been reported.(9) In a feasibility trial of antidepressant therapy, Yohannes et al.”
BackgroundInfluentialSleep Disorders in the Elderly With and Without Chronic Airflow Obstruction: the SARA Study
Bellia, V., Catalano, F., Scichilone, N., Incalzi, R. A., Spatafora, M., Vergani, C., & Rengo, F. (2003) · SLEEP · doi:10.1093/sleep/26.3.318 · Cited by 101
Depression and anxiety in elderly patients with chronic obstructive pulmonary disease
Yohannes, A. M., Baldwin, R., & Connolly, M. J. (2006) · Age and Ageing · doi:10.1093/ageing/afl011 · Cited by 93
Coventry, P. A., & Gellatly, J. L. (2008) · British Journal of Health Psychology · doi:10.1348/135910707x203723 · Cited by 86
Persoons, P., Luyckx, K., Desloovere, C., Vandenberghe, J. U., & Fischler, B. (2003) · General Hospital Psychiatry · doi:10.1016/s0163-8343(03)00072-0 · Cited by 83
IV. GROWTH CURVE ANALYSIS: AN INTRODUCTION TO VARIOUS METHODS FOR ANALYZING LONGITUDINAL DATA
Burchinal, M. R., Nelson, L. M., & Poe, M. (2006) · Monographs of the Society for Research in Child Development · doi:10.1111/j.1540-5834.2006.00405.x · Cited by 82
Vangeneugden, T., Laenen, A., Geys, H., Renard, D., & Molenberghs, G. (2004) · Controlled Clinical Trials · doi:10.1016/j.cct.2003.08.009 · Cited by 75
Factors affecting health status in COPD patients with co-morbid anxiety or depression.
Hynninen, M. J., Pallesen, S., & Nordhus, I. H. (2007) · PubMed Central · Cited by 71
Self-citationThe GOLD Classification Has Not Advanced Understanding of COPD
Kerstjens, H. A. M. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2405010 · Cited by 71
Depression and Chronic Obstructive Pulmonary Disease: Treatment Trials.
Borson, S., Claypoole, K. H., & McDonald, G. (1998) · PubMed · Cited by 70
Stanley, M. A., & Beck, J. G. (2000) · Clinical Psychology Review · doi:10.1016/s0272-7358(99)00064-1 · Cited by 67
Ninot, G., Fortes, M., Poulain, M., Brun, A., Desplan, J., PREFAUT, C. G., & Varray, A. L. (2006) · Heart & Lung · doi:10.1016/j.hrtlng.2005.09.004 · Cited by 52
Developing an intervention for depressed, chronically medically ill elders: A model from COPD
Alexopoulos, G. S., Raue, P. J., Sirey, J. A., & Arean, P. A. (2008) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1925 · Cited by 48 · cited 1×
“Problem-solving skills-training to address behavioral limitations as well as access to a care manager who works with the patient to identify and overcome the specific barriers have been suggested as ways to improve adherence to treatment.(41,43) Future studies should compare individually delivered CBT to group CBT, as…”
BackgroundAn intervention to improve depression care in older adults with COPD
Sirey, J. A., Raue, P. J., & Alexopoulos, G. S. (2006) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1705 · Cited by 47
The GOLD Classification Has Advanced Understanding of COPD
Calverley, P. M. A. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2405008 · Cited by 35
Anxiety and depression in chronic obstructive pulmonary disease: A new intervention and case report
Stanley, M. A., Veazey, C. H., Hopko, D. R., Diefenbach, G. J., & Kunik, M. E. (2005) · Cognitive and Behavioral Practice · doi:10.1016/s1077-7229(05)80070-7 · Cited by 26
Women and Chronic Obstructive Pulmonary Disease
Mannino, D. M. (2006) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200606-805ed · Cited by 11
Research works printed but not linked: 2
- National Institute of Clinical Excellence, 2004, Managing stable COPD, Thorax, 59, i39
- Bellia, 2003, Sleep disorders in the elderly with and without chronic airflow obstruction: the SARA study, Sleep, 26, 318, 10.1093/sleep/26.3.318 · DOI
Cited by
Sorted by citations
Lenferink, A., Brusse-Keizer, M., van der Valk, P. D., Frith, P. A., Zwerink, M., Monninkhof, E. M., van der Palen, J., & Effing, T. W. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011682.pub2 · Cited by 328
Anxiety and depression-Important psychological comorbidities of COPD.
Pumar, M., Gray, C. R., Walsh, J., Yang, I. A., Rolls, T., & Ward, D. L. (2014) · PubMed · doi:10.3978/j.issn.2072-1439.2014.09.28 · Cited by 288
Coventry, P., Panagioti, M., Scott, C., & Blakemore, A. (2014) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s72073 · Cited by 249
Zhang, M. W., Ho, R., Cheung, M. W. ‐., Fu, E., & Mak, A. (2011) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2011.03.009 · Cited by 236
Sleep Disorders in Chronic Obstructive Pulmonary Disease: Etiology, Impact, and Management
Budhiraja, R., Siddiqi, T., & Quan, S. F. (2015) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.4540 · Cited by 219
Metadata
- Authors
- Hynninen, M. J., Bjerke, N., Pallesen, S., Bakke, P. S., & Nordhus, I. H.
- Affiliations
- University of Bergen (NO)
- Haukeland University Hospital (NO)
- Corresponding author
- Hynninen, Minna J.
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 104
- Issue
- 7
- Pages
- 986-994
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2141347382
- Cited by
- 152
- References
- 44
- Citations by year
- 2026: 7 · 2025: 7 · 2024: 6 · 2023: 13 · 2022: 6 · 2021: 6 · 2020: 8 · 2019: 7 · 2018: 6 · 2017: 16 · 2016: 11 · 2015: 10 · 2014: 21 · 2013: 6 · 2012: 12
- FWCI
- 7.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, chronic obstructive pulmonary disease, anxiety, depression, comorbidities, group therapy, sex differences, age differences, sleep, health status, mental health integration
- MeSH terms
- Adult, Aged, Anxiety Disorders, Depressive Disorder, Female, Humans, Male, Middle Aged, Norway, Quality of Life, Surveys and Questionnaires, Cognitive Behavioral Therapy, Treatment Outcome, Pulmonary Disease, Chronic Obstructive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
