Overview of the prevalence, impact, and management of depression and anxiety in chronic obstructive pulmonary disease
Open accessAbstract
More than one third of individuals with chronic obstructive pulmonary disease (COPD) experience comorbid symptoms of depression and anxiety. This review aims to provide an overview of the burden of depression and anxiety in those with COPD and to outline the contemporary advances and challenges in the management of depression and anxiety in COPD. Symptoms of depression and anxiety in COPD lead to worse health outcomes, including impaired health-related quality of life and increased mortality risk. Depression and anxiety also increase health care utilization rates and costs. Although the quality of the data varies considerably, the cumulative evidence shows that complex interventions consisting of pulmonary rehabilitation interventions with or without psychological components improve symptoms of depression and anxiety in COPD. Cognitive behavioral therapy is also an effective intervention for managing depression in COPD, but treatment effects are small. Cognitive behavioral therapy could potentially lead to greater benefits in depression and anxiety in people with COPD if embedded in multidisciplinary collaborative care frameworks, but this hypothesis has not yet been empirically assessed. Mindfulness-based treatments are an alternative option for the management of depression and anxiety in people with long-term conditions, but their efficacy is unproven in COPD. Beyond pulmonary rehabilitation, the evidence about optimal approaches for managing depression and anxiety in COPD remains unclear and largely speculative. Future research to evaluate the effectiveness of novel and integrated care approaches for the management of depression and anxiety in COPD is warranted.
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Mindfulness-based interventions are effective in improving mindful awareness, CD3+ T cell number, CD4+ T cell number and depression, and in reducing the nutritional risk index and CD8+ T cell number in patients with COPD.
“It is verified that MBIs are effective in improving mindful awareness, CD3+ T cell number, CD4+ T cell number28 and depression,29 reducing the nutritional risk index and CD8+ T cell number in patients with COPD.28”
From The efficacy of mindfulness-based interventions for patients with COPD: A systematic review and meta-analysis protocol (2019) · cites this paper as [29]
Citation 29 is attached to the claim that mindfulness-based interventions improve depression in patients with COPD. In Results > Implications for practice and research (page unavailable), the source says that mindfulness meditation’s effectiveness among COPD patients has not yet been confirmed, contrary to the sentence’s assertion that it is verified. (LLM, conf=0.88)
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- Authors
- Coventry, P., Panagioti, M., Scott, C., & Blakemore, A.
- Affiliations
- Manchester Academic Health Science Centre (GB)
- Corresponding author
- Coventry, Peter
- Venue
- International Journal of Chronic Obstructive Pulmonary Disease
- Publisher
- Informa UK Limited
- Published
- 2014-11
- Volume
- 9
- Pages
- 1289
- ISSN
- 1176-9106 (ISSN-L)
- 1178-2005
- PMC
- PMC4235478
- OpenAlex
- W2014085762
- Cited by
- 249
- References
- 32
- Citations by year
- 2026: 6 · 2025: 22 · 2024: 20 · 2023: 17 · 2022: 29 · 2021: 35 · 2020: 21 · 2019: 30 · 2018: 16 · 2017: 19 · 2016: 26 · 2015: 7
- FWCI
- 2.97
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of COPD (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Dove Medical Press (Taylor and Francis Group) (submittedVersion, cc-by-nc)
- Funders
- National Institute for Health and Care Research
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- chronic obstructive pulmonary disease, depression, anxiety, comorbidities, pulmonary rehabilitation, cognitive behavioral therapy, mindfulness-based interventions, collaborative care, health-related quality of life, health care utilization, psychological intervention
- MeSH terms
- Anxiety, Combined Modality Therapy, Depression, Humans, Health Knowledge, Attitudes, Practice, Patient Care Team, Quality of Life, Health Behavior, Comorbidity, Prevalence, Treatment Outcome, Pulmonary Disease, Chronic Obstructive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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