Cited by 104Nanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic ImagingCarbon and Quantum Dots Applications

Functionalization of small black phosphorus nanoparticles for targeted imaging and photothermal therapy of cancer

Deng, Lijuan, Xu, Yifan, Sun, Caixia, Yun, Baofeng, Sun, Qiao, Zhao, Chongjun, Li, Zhen·2018·Science Bulletin

Abstract

Black phosphorus (BP) nanomaterials have attracted extensive attention due to their unique physical, chemical, and biological properties. In this study, small BP nanoparticles were synthesized and modified with dextran and poly(ethyleneimine) for functionalization with folic acid and cyanine 7. The functionalized BP nanoparticles exhibit excellent biocompatibility, stability, and near infrared optical properties for targeted imaging of tumors through photoacoustic imaging and near-infrared fluorescence imaging. They also display high photothermal conversion efficiency for photothermal therapy of cancer. This work demonstrates the potential of functionalized small BP nanoparticles as an emerging nanotheranostic agent for the diagnosis and treatment of cancer.

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Registry

Crossref · 10.1016/j.scib.2018.05.022

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36 of 36 references verified0 citation errors · 0 not checkable

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  • BP has outstanding photothermal properties when exposed to NIR radiation, opening applications for cancer photoacoustic imaging and PTT.

    “It is widely known that BP has outstanding photothermal properties when exposed to NIR radiation, which opens up a wide range of applications for it as smart nanoparticles for cancer photoacoustic (PA) imaging and PTT.120”

    From Smart nanoparticles for cancer therapy (2023) · cites this paper as [120]

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Authors
Deng, L., Xu, Y., Sun, C., Yun, B., Sun, Q., Zhao, C., & Li, Z.
Affiliations
  • East China University of Science and Technology (CN)
  • Soochow University (CN)
Corresponding author
  • Zhao, Chongjun
  • Li, Zhen
Venue
Science Bulletin
Publisher
Elsevier BV
Published
2018-07
Volume
63
Issue
14
Pages
917-924
ISSN
2095-9273 (ISSN-L)
OpenAlex
W2803634211
Cited by
104
References
36
Citations by year
2026: 6 · 2025: 15 · 2024: 17 · 2023: 8 · 2022: 13 · 2021: 17 · 2020: 13 · 2019: 13 · 2018: 2
FWCI
4.50
Type
journal article
Language
en
Open access
closed
Locations
  • 中国科学通报:英文版 (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Natural Science Foundation of China (81471657, 81527901)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
  • Physical Sciences › Engineering › Biomedical Engineering › Photoacoustic and Ultrasonic Imaging
  • Physical Sciences › Materials Science › Materials Chemistry › Carbon and Quantum Dots Applications
Keywords
nanoparticle functionalization, dextran coating, poly(ethyleneimine), folic acid, targeted imaging, photoacoustic imaging, near-infrared fluorescence imaging, photothermal therapy, cancer nanotheranostics, near-infrared optical properties

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