Cited by 579Pharmaceutical and Antibiotic Environmental ImpactsUrban Stormwater Management SolutionsWater Quality and Pollution Assessment

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Urban contribution of pharmaceuticals and other organic wastewater contaminants to streams during differing flow conditions

KOLPIN, D, SKOPEC, M, MEYER, M, FURLONG, E, ZAUGG, S·2004·Science of The Total Environment

DOI 10.1016/j.scitotenv.2004.01.015

Open this paper in CoChat — free account

Abstract

During 2001, 76 water samples were collected upstream and downstream of select towns and cities in Iowa during high-, normal- and low-flow conditions to determine the contribution of urban centers to concentrations of pharmaceuticals and other organic wastewater contaminants (OWCs) in streams under varying flow conditions. The towns ranged in population from approximately 2000 to 200,000. Overall, one or more OWCs were detected in 98.7% of the samples collected, with 62 of the 105 compounds being found. The most frequently detected compounds were metolachlor (pesticide), cholesterol (plant and animal sterol), caffeine (stimulant), beta-sitosterol (plant sterol) and 1,7-dimethylxanthine (caffeine degradate). The number of OWCs detected decreased as streamflow increased from low- (51 compounds detected) to normal- (28) to high-flow (24) conditions. Antibiotics and other prescription drugs were only frequently detected during low-flow conditions. During low-flow conditions, 15 compounds (out of the 23) and ten compound groups (out of 11) detected in more than 10% of the streams sampled had significantly greater concentrations in samples collected downstream than in those collected upstream of the urban centers. Conversely, no significant differences in the concentrations were found during high-flow conditions. Thus, the urban contribution of OWCs to streams became progressively muted as streamflow increased.

Integrity signals

Registry

Crossref · 10.1016/j.scitotenv.2004.01.015

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999–2000: A National Reconnaissance
Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es011055j · Cited by 7,953
Self-citation
Pharmaceuticals and Personal Care Products in the Environment: Agents of Subtle Change?
Daughton, C. G., & Ternes, T. A. (1999) · Environmental Health Perspectives · doi:10.1289/ehp.99107s6907 · Cited by 4,703
Occurrence of drugs in German sewage treatment plants and rivers
Ternes, T. A. (1998) · Water Research · doi:10.1016/s0043-1354(98)00099-2 · Cited by 3,502
Occurrence, fate and effects of pharmaceutical substances in the environment- A review
Halling-Sørensen, B., Nors Nielsen, S., Lanzky, P. F., Ingerslev, F., Holten Lützhøft, H. C., & Jørgensen, S. E. (1998) · Chemosphere · doi:10.1016/s0045-6535(97)00354-8 · Cited by 3,285
Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data
Heberer, T. (2002) · Toxicology Letters · doi:10.1016/s0378-4274(02)00041-3 · Cited by 2,995
Statistical Methods in Water Resources
Helsel, D. R., & Hirsch, R. M. (1992) · Studies in environmental science · doi:10.1016/s0166-1116(08)x7035-9 · Cited by 2,892
Response to Comment on “Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance”
Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., & Buxton, H. T. (2002) · Environmental Science & Technology · doi:10.1021/es0201350 · Cited by 1,706
Self-citation
Removal of Pharmaceuticals during Drinking Water Treatment
Ternes, T. A., Meisenheimer, M., McDowell, D. C., Sacher, F., Brauch, H., Haist-Gulde, B., Preuß, G., Willme, U., & Zullei-Seibert, N. (2002) · Environmental Science & Technology · doi:10.1021/es015757k · Cited by 1,293
Something from “Nothing” − Eight Weak Estrogenic Chemicals Combined at Concentrations below NOECs Produce Significant Mixture Effects
Silva, E., Rajapakse, N., & Kortenkamp, A. (2002) · Environmental Science & Technology · doi:10.1021/es0101227 · Cited by 914
Determination of Endocrine-Disrupting Phenolic Compounds and Estrogens in Surface and Drinking Water by HRGC−(NCI)−MS in the Picogram per Liter Range
Kuch, H., & Ballschmiter, K. (2001) · Environmental Science & Technology · doi:10.1021/es010034m · Cited by 740

Show all 40 references

Sorted by citations

A Review on the Occurrence of Micropollutants in the Aquatic Environment and Their Fate and Removal during Wastewater Treatment
Luo, Y., Guo, W., Ngo, H. H., Nghiem, L. D., Hai, F. I., Zhang, J., Liang, S., & Wang, X. C. (2014) · Science of The Total Environment · doi:10.1016/j.scitotenv.2013.12.065 · Cited by 3,983
Ecotoxicology of human pharmaceuticals
Fent, K., Weston, A. A., & Caminada, D. (2006) · Aquatic Toxicology · doi:10.1016/j.aquatox.2005.09.009 · Cited by 3,223
The removal of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs during wastewater treatment and its impact on the quality of receiving waters
Kasprzyk‐Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2008) · Water Research · doi:10.1016/j.watres.2008.10.047 · Cited by 1,755
Occurrence and toxicity of antibiotics in the aquatic environment: A review
Kovalakova, P., Cizmas, L. H., McDonald, T. J., Maršálek, B., Feng, M., & Sharma, V. K. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126351 · Cited by 1,495
Pharmaceuticals and personal care products (PPCPs): A review on environmental contamination in China
Liu, J.-L., & Wong, M. H. (2013) · Environment International · doi:10.1016/j.envint.2013.06.012 · Cited by 1,395
The occurrence of antibiotics in an urban watershed: From wastewater to drinking water
Watkinson, A., Murby, E. J., Kolpin, D. W., & Costanzo, S. D. (2009) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.11.059 · Cited by 1,247
Self-citation
Removal of antibiotics in conventional and advanced wastewater treatment: Implications for environmental discharge and wastewater recycling
Watkinson, A., Murby, E. J., & Costanzo, S. D. (2007) · Water Research · doi:10.1016/j.watres.2007.04.005 · Cited by 1,218
The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK
Kasprzyk‐Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2008) · Water Research · doi:10.1016/j.watres.2008.04.026 · Cited by 1,190
A review of personal care products in the aquatic environment: Environmental concentrations and toxicity
Brausch, J. M., & Rand, G. M. (2010) · Chemosphere · doi:10.1016/j.chemosphere.2010.11.018 · Cited by 1,093
The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment
ROBERTS, P., & Thomas, K. V. (2005) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2005.04.031 · Cited by 953
Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: Implications for environmental risk assessment
González-Pleiter, M., Gonzalo, S., Rodea‐Palomares, I., Leganés, F., Rosal, R., Boltes, K., Marco, E., & Fernández‐Piñas, F. (2013) · Water Research · doi:10.1016/j.watres.2013.01.020 · Cited by 809
Global Synthesis and Critical Evaluation of Pharmaceutical Data Sets Collected from River Systems
Hughes, S. R., Kay, P., & Brown, L. E. (2012) · Environmental Science & Technology · doi:10.1021/es3030148 · Cited by 817
Efficiency of conventional drinking-water-treatment processes in removal of pharmaceuticals and other organic compounds
Stackelberg, P. E., Gibs, J., Furlong, E. T., Meyer, M. T., Zaugg, S. D., & Lippincott, R. L. (2007) · Science of The Total Environment · doi:10.1016/j.scitotenv.2007.01.095 · Cited by 749
Self-citation
Transport of Chemical and Microbial Compounds from Known Wastewater Discharges: Potential for Use as Indicators of Human Fecal Contamination
Glassmeyer, S. T., Furlong, E. T., Kolpin, D. W., Cahill, J. D., Zaugg, S. D., Werner, S. L., Meyer, M. T., & Kryak, D. D. (2005) · Environmental Science & Technology · doi:10.1021/es048120k · Cited by 724
Self-citation
Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea
Kim, Y., Choi, K., Jung, J., Park, S., Kim, P., & Park, J. (2007) · Environment International · doi:10.1016/j.envint.2006.11.017 · Cited by 672
Seasonal Variations in Concentrations of Pharmaceuticals and Personal Care Products in Drinking Water and Reclaimed Wastewater in Southern California
Loraine, G. A., & Pettigrove, M. E. (2005) · Environmental Science & Technology · doi:10.1021/es051380x · Cited by 659
Antibiotic Use in Agriculture and Its Impact on the Terrestrial Environment
Kumar, K., Gupta, S. C., Chander, Y., & Singh, A. K. (2005) · Advances in agronomy · doi:10.1016/s0065-2113(05)87001-4 · Cited by 637
Prioritizing research for trace pollutants and emerging contaminants in the freshwater environment
Murray, K. E., Thomas, S. M., & Bodour, A. A. (2010) · Environmental Pollution · doi:10.1016/j.envpol.2010.08.009 · Cited by 614
Pilot survey monitoring pharmaceuticals and related compounds in a sewage treatment plant located on the Mediterranean coast
Gómez, M. J., Bueno, M. J. M., Lacorte, S., Fernández‐Alba, A. R., & Agüera, A. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2006.07.051 · Cited by 607
Antidepressant Pharmaceuticals in Two U.S. Effluent-Impacted Streams: Occurrence and Fate in Water and Sediment, and Selective Uptake in Fish Neural Tissue
Schultz, M. M., Furlong, E. T., Kolpin, D. W., Werner, S. L., Schoenfuss, H. L., Barber, L. B., Blazer, V. S., Norris, D. O., & Vajda, A. M. (2010) · Environmental Science & Technology · doi:10.1021/es9022706 · Cited by 540
Self-citation
Occurrence of steroid estrogens, endocrine-disrupting phenols, and acid pharmaceutical residues in urban riverine water of the Pearl River Delta, South China
Peng, X., Yu, Y., Tang, C., Tan, J., Huang, Q., & Wang, Z. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.02.059 · Cited by 553
Temporal and Spatial Trends in the Occurrence of Human and Veterinary Antibiotics in Aqueous and River Sediment Matrices
Kim, S. C., & Carlson, K. (2006) · Environmental Science & Technology · doi:10.1021/es060737+ · Cited by 543
Removal of Antibiotics in Wastewater: Effect of Hydraulic and Solid Retention Times on the Fate of Tetracycline in the Activated Sludge Process
Kim, S., Eichhorn, P., Jensen, J. N., Weber, A. S., & Aga, D. S. (2005) · Environmental Science & Technology · doi:10.1021/es050006u · Cited by 517
Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed
Metcalfe, C. D., Chu, S., Judt, C., Li, H., Oakes, K. D., Servos, M. R., & Andrews, D. M. (2010) · Environmental Toxicology and Chemistry · doi:10.1002/etc.27 · Cited by 506
Occurrence and fate of antibiotics in the Seine River in various hydrological conditions
Tamtam, F., Mercier, F., Bot, B. L., Eurin, J., Dinh, Q. T., Clément, M., & Chevreuil, M. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2007.12.009 · Cited by 524
Survey of Organic Wastewater Contaminants in Biosolids Destined for Land Application
Kinney, C. A., Furlong, E. T., Zaugg, S. D., Burkhardt, M. R., Werner, S. L., Cahill, J. D., & Jorgensen, G. R. (2006) · Environmental Science & Technology · doi:10.1021/es0603406 · Cited by 493
Self-citation
Pharmacologically active compounds in the environment and their chirality
Kasprzyk‐Hordern, B. (2010) · Chemical Society Reviews · doi:10.1039/c000408c · Cited by 472
Identifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce
Howard, P. H., & Muir, D. C. G. (2010) · Environmental Science & Technology · doi:10.1021/es903383a · Cited by 445
Environmental risk assessment of pharmaceuticals in rivers: Relationships between hazard indexes and aquatic macroinvertebrate diversity indexes in the Llobregat River (NE Spain)
Ginebreda, A., Muñoz, I., de Alda, M. L., Brix, R., López‐Doval, J. C., & Barceló, ‪. (2009) · Environment International · doi:10.1016/j.envint.2009.10.003 · Cited by 432
Human pharmaceuticals in US surface waters: A human health risk assessment
Schwab, B. W., Hayes, E. P., Fiori, J. M., Mastrocco, F. J., Roden, N. M., Cragin, D., Meyerhoff, R. D., D’Aco, V. J., & Anderson, P. D. (2005) · Regulatory Toxicology and Pharmacology · doi:10.1016/j.yrtph.2005.05.005 · Cited by 427
Toxicological relevance of emerging contaminants for drinking water quality
Schriks, M., Heringa, M. B., van der Kooi, M. M. E., de Voogt, P., & van Wezel, A. P. (2009) · Water Research · doi:10.1016/j.watres.2009.08.023 · Cited by 409
Demonstration of 20 pharmaceuticals and personal care products (PPCPs) as nitrosamine precursors during chloramine disinfection
Shen, R., & Andrews, S. A. (2011) · Water Research · doi:10.1016/j.watres.2010.09.036 · Cited by 388
Lessons from Endocrine Disruption and Their Application to Other Issues Concerning Trace Organics in the Aquatic Environment
Sumpter, J. P., & Johnson, A. C. (2005) · Environmental Science & Technology · doi:10.1021/es048504a · Cited by 387
Multi-residue method for the determination of basic/neutral pharmaceuticals and illicit drugs in surface water by solid-phase extraction and ultra performance liquid chromatography–positive electrospray ionisation tandem mass spectrometry
Kasprzyk‐Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2007) · Journal of Chromatography A · doi:10.1016/j.chroma.2007.05.074 · Cited by 396
Monitoring release of pharmaceutical compounds: Occurrence and environmental risk assessment of two WWTP effluents and their receiving bodies in the Po Valley, Italy
Aukidy, M. A., Verlicchi, P., Jelić, A., Petrović, M., & Barceló, ‪. (2012) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2012.08.061 · Cited by 404
Wastewater treatment plants as a pathway for aquatic contamination by pharmaceuticals in the Ebro river basin (Northeast Spain)
Gros, M., Petrović, M., & Barceló, ‪. (2007) · Environmental Toxicology and Chemistry · doi:10.1897/06-495r.1 · Cited by 367
Comment on “Lessons from Endocrine Disruption and Their Application to Other Issues Concerning Trace Organics in the Aquatic Environment”
Segner, H. (2005) · Environmental Science & Technology · doi:10.1021/es051791d · Cited by 359
Occurrence of endocrine disrupting compounds, pharmaceuticals, and personal care products in the Han River (Seoul, South Korea)
Yoon, Y., Ryu, J., Oh, J., Choi, B. G., & Snyder, S. A. (2009) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2009.10.049 · Cited by 366
Ibuprofen removal by heated persulfate in aqueous solution: A kinetics study
Ghauch, A., Tuqan, A. M., & Kibbi, N. (2012) · Chemical Engineering Journal · doi:10.1016/j.cej.2012.05.051 · Cited by 337
Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea
Choi, K., Kim, Y., Park, J., Park, C. K., Kim, M., Kim, H. S., & Kim, P. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.06.038 · Cited by 333
Multiresidue methods for the analysis of pharmaceuticals, personal care products and illicit drugs in surface water and wastewater by solid-phase extraction and ultra performance liquid chromatography–electrospray tandem mass spectrometry
Kasprzyk‐Hordern, B., Dinsdale, R. M., & Guwy, A. J. (2008) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-008-1854-x · Cited by 333
Environmental Exposure of Aquatic and Terrestrial Biota to Triclosan and Triclocarban1
Chalew, T. E. A., & Halden, R. U. (2009) · JAWRA Journal of the American Water Resources Association · doi:10.1111/j.1752-1688.2008.00284.x · Cited by 324
The distribution and partitioning of common antibiotics in water and sediment of the Pearl River Estuary, South China
Liang, X., Chen, B., Nie, X., Shi, Z., Huang, X., & Li, X. D. (2013) · Chemosphere · doi:10.1016/j.chemosphere.2013.03.044 · Cited by 299
Occurrence, control and fate of contaminants of emerging concern in environmental compartments in Brazil
Starling, M. C. V. M., Amorim, C. C., & Leão, M. M. D. (2018) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2018.04.043 · Cited by 296
Occurrence and Fate of Pharmaceuticals and Personal Care Products (PPCPs) in Biosolids
Xia, K., Bhandari, A., Das, K. C., & Pillar, G. (2005) · Journal of Environmental Quality · doi:10.2134/jeq2005.0091 · Cited by 296
Antibiotics in the aquatic environment of Vietnam: Sources, concentrations, risk and control strategy
Binh, V. N., Dang, N., Anh, N. T. K., Ky, L. X., & Thai, P. K. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.01.061 · Cited by 300
Removal of cosmetic ingredients and pharmaceuticals in sewage primary treatment
Carballa, M., Omil, F., & Lema, J. M. (2005) · Water Research · doi:10.1016/j.watres.2005.09.018 · Cited by 289
Review of the Occurrence of Anti-infectives in Contaminated Wastewaters and Natural and Drinking Waters
Segura, P. A., François, M., Gagnon, C., & Sauvé, S. (2009) · Environmental Health Perspectives · doi:10.1289/ehp.11776 · Cited by 298
Principles of ecotoxicology
Beasley, V. R., & Levengood, J. M. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-385926-6.00077-6 · Cited by 275
Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U.S. surface and finished drinking waters: A proposed ranking system
Kumar, A., & Xagoraraki, I. (2010) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2010.08.048 · Cited by 273
Cosmetic Ingredients as Emerging Pollutants of Environmental and Health Concern. A Mini-Review
Juliano, C., & Magrini, G. (2017) · Cosmetics · doi:10.3390/cosmetics4020011 · Cited by 259
Analysis of Ecologically Relevant Pharmaceuticals in Wastewater and Surface Water Using Selective Solid-Phase Extraction and UPLC−MS/MS
Batt, A. L., Kostich, M. S., & Lazorchak, J. M. (2008) · Analytical Chemistry · doi:10.1021/ac800066n · Cited by 273
Analytical methods for the determination of persistent ingredients of personal care products in environmental matrices
Peck, A. M. (2006) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-006-0728-3 · Cited by 260
Urban contributions of glyphosate and its degradate AMPA to streams in the United States
Kolpin, D. W., Thurman, E. M., Lee, E. A., Meyer, M. T., Furlong, E. T., & Glassmeyer, S. T. (2006) · Science of The Total Environment · doi:10.1016/j.scitotenv.2005.01.028 · Cited by 252
Self-citation
Carbamazepine as a Possible Anthropogenic Marker in Water: Occurrences, Toxicological Effects, Regulations and Removal by Wastewater Treatment Technologies
Hai, F. I., Yang, S., Asif, M. B., Sencadas, V., Shawkat, S., Sanderson‐Smith, M. L., Gorman, J., Xu, Z., & Yamamoto, K. (2018) · Water · doi:10.3390/w10020107 · Cited by 265
Naproxen abatement by thermally activated persulfate in aqueous systems
Ghauch, A., Tuqan, A. M., & Kibbi, N. (2015) · Chemical Engineering Journal · doi:10.1016/j.cej.2015.05.067 · Cited by 244
Occurrences and fate of selected human antibiotics in influents and effluents of sewage treatment plant and effluent-receiving river Yamuna in Delhi (India)
Mutiyar, P. K., & Mittal, A. K. (2013) · Environmental Monitoring and Assessment · doi:10.1007/s10661-013-3398-6 · Cited by 243
Environmental footprint of pharmaceuticals: The significance of factors beyond direct excretion to sewers
Daughton, C. G., & Ruhoy, I. S. (2009) · Environmental Toxicology and Chemistry · doi:10.1897/08-382.1 · Cited by 243
Metal-organic frameworks (MOFs) as futuristic options for wastewater treatment
Kumar, P., Bansal, V., Kim, K., & Kwon, E. E. (2018) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2017.12.051 · Cited by 238
Contaminants of emerging concern in municipal wastewater effluents and marine receiving water
Vidal‐Dorsch, D. E., Bay, S. M., Maruya, K. A., Snyder, S. A., Trenholm, R. A., & Vanderford, B. J. (2012) · Environmental Toxicology and Chemistry · doi:10.1002/etc.2004 · Cited by 249
Pharmaceuticals in On‐Site Sewage Effluent and Ground Water, Western Montana
Godfrey, E., WOESSNER, W. W., & Benotti, M. J. (2007) · Ground Water · doi:10.1111/j.1745-6584.2006.00288.x · Cited by 241
Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography–tandem mass spectrometry
Al-Odaini, N. A., Zakaria, M. P., Yaziz, M. I., & Surif, S. (2010) · Journal of Chromatography A · doi:10.1016/j.chroma.2010.08.033 · Cited by 239
Reduction of pharmaceutically active compounds by a lagoon wetland wastewater treatment system in Southeast Louisiana
Conkle, J. L., White, J. R., & Metcalfe, C. D. (2008) · Chemosphere · doi:10.1016/j.chemosphere.2008.09.020 · Cited by 229
Connectivity of Streams and Wetlands to Downstream Waters: An Integrated Systems Framework
Leibowitz, S. G., Wigington, P. J., Schofield, K. A., Alexander, L. C., Vanderhoof, M. K., & Golden, H. E. (2018) · JAWRA Journal of the American Water Resources Association · doi:10.1111/1752-1688.12631 · Cited by 221
Occurrence of Emerging Contaminants in Brazilian Drinking Waters: A Sewage-To-Tap Issue
Sodré, F. F., Locatelli, M. A. F., & Jardim, W. F. (2009) · Water Air & Soil Pollution · doi:10.1007/s11270-009-0086-9 · Cited by 230
Occurrence and source apportionment of pharmaceuticals and personal care products in the Beiyun River of Beijing, China
Dai, G., Wang, B., Huang, J. G., Dong, R., Deng, S., & Yu, G. (2014) · Chemosphere · doi:10.1016/j.chemosphere.2014.08.056 · Cited by 220
Oxidation of fluoroquinolone antibiotics and structurally related amines by chlorine dioxide: Reaction kinetics, product and pathway evaluation
Wang, P., He, Y., & Huang, C. (2010) · Water Research · doi:10.1016/j.watres.2010.07.053 · Cited by 224
A preliminary study on the occurrence and behavior of sulfonamides, ofloxacin and chloramphenicol antimicrobials in wastewaters of two sewage treatment plants in Guangzhou, China
Peng, X., Wang, Z., Kuang, W., Tan, J., & Li, K. (2006) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2006.07.001 · Cited by 224
Preliminary risk assessment database and risk ranking of pharmaceuticals in the environment
Cooper, E. R., Siewicki, T. C., & Phillips, K. G. (2008) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2008.02.061 · Cited by 223
Novel technologies for reverse osmosis concentrate treatment: A review
Joo, S. H., & Tansel, B. (2014) · Journal of Environmental Management · doi:10.1016/j.jenvman.2014.10.027 · Cited by 211
Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in stormwater canals and Bayou St. John in New Orleans, Louisiana, USA
Boyd, G. R., Palmeri, J. M., Zhang, S., & Grimm, D. A. (2004) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2004.03.018 · Cited by 219
Temporal and spatial variation in pharmaceutical concentrations in an urban river system
Burns, E. E., Carter, L., Kolpin, D. W., THOMAS‐OATES, J. E., & Boxall, A. B. A. (2018) · Water Research · doi:10.1016/j.watres.2018.02.066 · Cited by 210
Self-citation
An exposure assessment for selected pharmaceuticals within a watershed in Southern Ontario
Lissemore, L. I., Hao, C., Yang, P., Sibley, P. K., Mabury, S. A., & Solomon, K. R. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2005.11.015 · Cited by 213
Chronic effects of exposure to a pharmaceutical mixture and municipal wastewater in zebrafish
Galus, M., Jeyaranjaan, J., Smith, E. M., Li, H., Metcalfe, C. D., & Wilson, J. Y. (2013) · Aquatic Toxicology · doi:10.1016/j.aquatox.2012.12.016 · Cited by 220
Synthesis of carbon xerogels and their application in adsorption studies of caffeine and diclofenac as emerging contaminants
Álvarez-Torrellas, S., Ribeiro, R. S., Gomes, H. T., Sotelo, J. L., & Garcı́a, J. (2014) · Process Safety and Environmental Protection · doi:10.1016/j.cherd.2014.11.001 · Cited by 209
Photochemical Formation of Hydroxyl Radical from Effluent Organic Matter
Dong, M., & Rosario‐Ortiz, F. L. (2012) · Environmental Science & Technology · doi:10.1021/es2043454 · Cited by 210
Ozonation of oxytetracycline and toxicological assessment of its oxidation by-products
Li, K., Yediler, A., Yang, M., Schulte‐Hostede, S., & Wong, M. H. (2008) · Chemosphere · doi:10.1016/j.chemosphere.2008.02.008 · Cited by 209
Investigating landfill leachate as a source of trace organic pollutants
Clarke, B. O., Anumol, T., Barlaz, M., & Snyder, S. A. (2015) · Chemosphere · doi:10.1016/j.chemosphere.2015.02.030 · Cited by 195
Current research in urban hydrogeology – A review
Schirmer, M., Leschik, S., & Musolff, A. (2012) · Advances in Water Resources · doi:10.1016/j.advwatres.2012.06.015 · Cited by 195
Monitoring the degradation of tetracycline by ozone in aqueous medium via atmospheric pressure ionization mass spectrometry
Dalmázio, I., Almeida, M. O., Augusti, R., & Alves, T. M. D. A. (2007) · Journal of the American Society for Mass Spectrometry · doi:10.1016/j.jasms.2006.12.001 · Cited by 194
Differential exposure, duration, and sensitivity of unionoidean bivalve life stages to environmental contaminants
Cope, W. G., Bringolf, R. B., Buchwalter, D. B., Newton, T. J., Ingersoll, C. G., Wang, N., Augspurger, T., Dwyer, F. J., Barnhart, M. C., Neves, R. J., et al. (2008) · Journal of the North American Benthological Society · doi:10.1899/07-094.1 · Cited by 195
Pesticides from wastewater treatment plant effluents affect invertebrate communities
Münze, R., Hannemann, C., Orlinskiy, P., Gunold, R., Paschke, A., Foit, K., Becker, J. M., Kaske, O., Paulsson, E., Peterson, M., et al. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.03.008 · Cited by 192
The potential for a suite of isotope and chemical markers to differentiate sources of nitrate contamination: A review
Fenech, C., Rock, L., Nolan, K. J. M., Tobin, J., & Morrissey, A. (2012) · Water Research · doi:10.1016/j.watres.2012.01.044 · Cited by 197
Performance of a microalgal photobioreactor treating toilet wastewater: Pharmaceutically active compound removal and biomass harvesting
Hom-Díaz, A., Jaén-Gil, A., Bello-Laserna, I., Rodríguez‐Mozaz, S., Vicent, T., Barceló, ‪., & Blánquez, P. (2017) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2017.02.224 · Cited by 191
Is there a risk associated with the insect repellent DEET (N,N-diethyl-m-toluamide) commonly found in aquatic environments?
Costanzo, S. D., Watkinson, A., Murby, E. J., Kolpin, D. W., & Sandstrom, M. W. (2007) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2007.05.036 · Cited by 196
Self-citation
Contamination levels of selected organochlorine and organophosphate pesticides in the Selangor River, Malaysia between 2002 and 2003
Leong, K. H., Tan, L., & Mohd, M. A. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2006.06.009 · Cited by 190
The impact of agricultural chemical inputs on environment: global evidence from informetrics analysis and visualization
Zhang, L., Yan, C., Guo, Q., Zhang, J., & Ruiz‐Menjivar, J. (2018) · International Journal of Low-Carbon Technologies · doi:10.1093/ijlct/cty039 · Cited by 197
Monitoring the photochemical degradation of triclosan in wastewater by UV light and sunlight using solid-phase microextraction
Sánchez-Prado, L., Llompart, M., Lores, M., Garcı́a-Jares, C., Bayona, J. M., & Cela, R. (2006) · Chemosphere · doi:10.1016/j.chemosphere.2006.04.025 · Cited by 193
Proclivities for prevalence and treatment of antibiotics in the ambient water: a review
Bhagat, C., Kumar, M., Tyagi, V. K., & Mohapatra, P. K. (2020) · npj Clean Water · doi:10.1038/s41545-020-00087-x · Cited by 187
Sources and transport of contaminants of emerging concern: A two-year study of occurrence and spatiotemporal variation in a mixed land use watershed
Fairbairn, D. J., Karpuzcu, M. E., Arnold, W. A., Barber, B. L., Kaufenberg, E. F., Koskinen, W. C., Novak, P. J., Rice, P. J., & Swackhamer, D. L. (2016) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2016.02.056 · Cited by 189
Occurrence, removal, mass loading and environmental risk assessment of emerging organic contaminants in leachates, groundwaters and wastewaters
Kapelewska, J., Kotowska, U., Karpińska, J., Kowalczuk, D., Arciszewska, A., & Świrydo, A. (2018) · Microchemical Journal · doi:10.1016/j.microc.2017.11.008 · Cited by 147
Contaminants in the coastal karst aquifer system along the Caribbean coast of the Yucatan Peninsula, Mexico
Metcalfe, C. D., Beddows, P. A., Bouchot, G. G., Metcalfe, T. L., Li, H., & Lavieren, H. V. (2011) · Environmental Pollution · doi:10.1016/j.envpol.2010.11.031 · Cited by 179
A review of non-point source water pollution modeling for the urban–rural transitional areas of China: Research status and prospect
Xue, J., Wang, Q., & Zhang, M. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154146 · Cited by 179
Antibacterial Activity of Soil‐Bound Antibiotics
Chander, Y., Kumar, K., Goyal, S. M., & Gupta, S. C. (2005) · Journal of Environmental Quality · doi:10.2134/jeq2005.0017 · Cited by 178
Concurrence of antibiotic resistant bacteria (ARB), viruses, pharmaceuticals and personal care products (PPCPs) in ambient waters of Guwahati, India: Urban vulnerability and resilience perspective
Kumar, M., Ram, B., Honda, R., Poopipattana, C., Canh, V. D., Chaminda, T., & Furumai, H. (2019) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2019.133640 · Cited by 172
Elimination of Endocrine Disrupting Chemicals using White Rot Fungi and their Lignin Modifying Enzymes: A Review
Cabana, H., Jones, J. P., & Agathos, S. N. (2007) · Engineering in Life Sciences · doi:10.1002/elsc.200700017 · Cited by 169
Distribution and Chemical Analysis of Pharmaceuticals and Personal Care Products (PPCPs) in the Environmental Systems: A Review
Ohoro, C. R., Adeniji, A. O., Okoh, A. I., & Okoh, O. O. (2019) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph16173026 · Cited by 172
Synthesis of novel ternary heterogeneous BiOCl/TiO2/sepiolite composite with enhanced visible-light-induced photocatalytic activity towards tetracycline
Hu, X., Sun, Z., Song, J., Zhang, G., Li, C., & Zheng, S. (2018) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2018.08.077 · Cited by 166
Development of extraction method of pharmaceuticals and their occurrences found in Japanese wastewater treatment plants
Okuda, T., Yamashita, N., Tanaka, H., Matsukawa, H., & Tanabe, K. (2009) · Environment International · doi:10.1016/j.envint.2009.01.006 · Cited by 175
Effects on feeding rate and biomarker responses of marine mussels experimentally exposed to propranolol and acetaminophen
Solé, M., Shaw, J. P., Frickers, P. E., Readman, J. W., & Hutchinson, T. H. (2009) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-009-3182-1 · Cited by 165

Authors: KOLPIN, D., SKOPEC, M., MEYER, M., FURLONG, E., & ZAUGG, S.
Affiliations: United States Geological Survey (US)
Iowa Geological Survey (US)
Corresponding author: KOLPIN, D
ORCID: KOLPIN, D
SKOPEC, M
MEYER, M
FURLONG, E
Venue: Science of The Total Environment
Publisher: Elsevier BV
Published: 2004-07-26
Volume: 328
Issue: 1-3
Pages: 119-130
ISSN: 0048-9697 (ISSN-L)
DOI: 10.1016/j.scitotenv.2004.01.015
OpenAlex: W1980686360
Cited by: 579
References: 40
Citations by year: 2026: 11 · 2025: 8 · 2024: 15 · 2023: 12 · 2022: 20 · 2021: 31 · 2020: 30 · 2019: 19 · 2018: 32 · 2017: 20 · 2016: 34 · 2015: 26 · 2014: 37 · 2013: 35 · 2012: 35
FWCI: 31.55
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Science of The Total Environment (publishedVersion)
PubMed (publishedVersion)
Funders: U.S. Geological Survey
Topics: Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
Physical Sciences › Environmental Science › Environmental Engineering › Urban Stormwater Management Solutions
Physical Sciences › Environmental Science › Water Science and Technology › Water Quality and Pollution Assessment
Keywords: pharmaceuticals, urban rivers, urban runoff, metolachlor, cholesterol, β-sitosterol, caffeine, 1,7-dimethylxanthine, antibiotics, prescription drugs, Iowa streams
MeSH terms: Chromatography, Liquid, Cities, Pharmaceutical Preparations, Environmental Monitoring, Iowa, Mass Spectrometry, Waste Disposal, Fluid, Rivers

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Urban contribution of pharmaceuticals and other organic wastewater contaminants to streams during differing flow conditions

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks