The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
COVID-19: A promising cure for the global panic
Open accessAbstract
The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
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“The distinguishing factor is probably the nucleotide changes in the spike (S) protein and its receptor-binding domain (RBD) (Kannan et al., 2020; Coutard et al., 2020;Wan et al., 2020).”
BackgroundCOVID-19 and the cardiovascular system
Zheng, Y.-Y., Ma, Y.-T., Zhang, J.-Y., & Xie, X. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-020-0360-5 · Cited by 2,970
Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)
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Coronavirus Disease 2019 (COVID-19): A Perspective from China
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“It has been reported that the SARS-CoV and SARS-CoV-2 have similar kind of receptors, especially the receptor binding domain (RBD) and the receptor binding motif (RBM) in the viral genome (Yin and Wunderink, 2018; Zhang et al., 2020; Tai et al., 2020) .”
COVID-19: combining antiviral and anti-inflammatory treatments
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Single-Cell RNA Expression Profiling of ACE2, the Receptor of SARS-CoV-2
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Single-cell RNA expression profiling of ACE2, the receptor of SARS-CoV-2
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Cited by
Prediction for the spread of COVID-19 in India and effectiveness of preventive measures
Tomar, A., & Gupta, N. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138762 · Cited by 445
Paital, B., Das, K., & Parida, S. K. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138914 · Cited by 281
Biosurfactants: A COVID-19 Perspective
Smith, M. L., Gandolfi, S., Coshall, P. M., & Rahman, P. K. S. M. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01341 · Cited by 96
Self-citation
Metadata
- Authors
- Vellingiri, B., Jayaramayya, K., Iyer, M., Narayanasamy, A., Govindasamy, V., Giridharan, B., Ganesan, S., Venugopal, A., Venkatesan, D., Ganesan, H., Rajagopalan, K., Rahman, P. K. S. M., Cho, S.-G., Kumar, N. S., & Subramaniam, M. D.
- Venue
- Science of The Total Environment
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 725
- Pages
- 138277
- ISSN
- 0048-9697 (ISSN-L)
- OpenAlex
- W3013467637
- Cited by
- 636
- References
- 14
- FWCI
- 17.56
- Type
- journal article
- Language
- en
- Open access
- green
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- Vellingiri, B., Jayaramayya, K., Iyer, M., Narayanasamy, A., Govindasamy, V., Giridharan, B., Ganesan, S., Venugopal, A., Venkatesan, D., Ganesan, H., Rajagopalan, K., Rahman, P. K. S. M., Cho, S.-G., Kumar, N. S., & Subramaniam, M. D. (2020). COVID-19: A promising cure for the global panic. Science of The Total Environment. https://doi.org/10.1016/j.scitotenv.2020.138277
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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