An update on the burden of musculoskeletal diseases in the U.S.
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Up to half of over 70 million Americans with chronic musculoskeletal pain have a comorbid diagnosis of depression and/or anxiety.
“Of the over 70 million Americans who have chronic musculoskeletal pain, up to half of them have a comorbid diagnosis of depression and/or anxiety [1-4].”
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- Authors
- Yelin, E., Weinstein, S., & King, T.
- Affiliations
- University of California, San Francisco (US)
- University of Iowa (US)
- United States Bone and Joint Initiative (US)
- Corresponding author
- Yelin, Edward
- ORCID
- Weinstein, Stuart
- Venue
- Seminars in Arthritis and Rheumatism
- Publisher
- Elsevier BV
- Published
- 2019-08
- Volume
- 49
- Issue
- 1
- Pages
- 1-2
- ISSN
- 0049-0172 (ISSN-L)
- OpenAlex
- W2943720717
- Cited by
- 33
- References
- 7
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 8 · 2022: 4 · 2021: 6 · 2020: 7
- FWCI
- 3.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Arthritis and Rheumatism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Keywords
- osteoarthritis, chlorogenic acid, polyphenols, chondrocytes, oxidative stress, apoptosis, autophagy, Nrf2, NF-κB, reactive oxygen species, antioxidant response, Bcl-xL, caspase-3, poly(ADP-ribose) polymerase, musculoskeletal disorders
- MeSH terms
- Adult, Age Factors, Aged, Female, Humans, Male, Middle Aged, Musculoskeletal Diseases, United States, Prevalence
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