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SOX2 in development and cancer biology
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SOX2 is developmentally essential; its absence results in embryonic lethality.
“SOX2 is a transcription factor expressed during the emergence of the inner cell mass and is a developmentally essential gene, as its absence results in embryonic lethality 45 .”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [45]
SOX2 is a transcription factor expressed during the emergence of the inner cell mass.
“SOX2 is a transcription factor expressed during the emergence of the inner cell mass and is a developmentally essential gene, as its absence results in embryonic lethality 45 .”
From Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming (2023) · cites this paper as [45]
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Takahashi, K., & Yamanaka, S. (2006) · Cell · doi:10.1016/j.cell.2006.07.024 · Cited by 26,673
A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
Polo, J. M., Anderssen, E., Walsh, R. M., Schwarz, B. A., Nefzger, C. M., Lim, S. M., Borkent, M., Apostolou, E., Alaei, S., Cloutier, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.11.039 · Cited by 861
Wood, H. B., & Episkopou, V. (1999) · Mechanisms of Development · doi:10.1016/s0925-4773(99)00116-1 · Cited by 550
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Driskell, R. R., Giangreco, A., Jensen, K. B., Mulder, K. W., & Watt, F. M. (2009) · Development · doi:10.1242/dev.038620 · Cited by 331
Yang, J., Liao, D., Chen, C., Liu, Y., Chuang, T.-H., Xiang, R., Markowitz, D., Reisfeld, R. A., & Luo, Y. (2013) · Stem Cells · doi:10.1002/stem.1281 · Cited by 301
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- Kregel, 2013, Sox2 Is an Androgen Receptor-Repressed Gene That Promotes Castration-Resistant Prostate Cancer, PLoS One, 8, e53701, 10.1371/journal.pone.0053701 · DOI
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Metadata
- Authors
- Novak, D., Hüser, L., Elton, J. J., Umansky, V., Altevogt, P., & Utikal, J.
- Venue
- Seminars in Cancer Biology
- Publisher
- Elsevier BV
- Published
- 2020-12
- Volume
- 67
- Pages
- 74-82
- ISSN
- 1044-579X
- Cited by
- 328
- References
- 5
- Language
- en
- Licence
- Funders
- Deutsche Forschungsgemeinschaft
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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