Nanoparticles guided drug delivery and imaging in gastric cancer
Abstract
Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP) -based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.
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The efficacy of repurposed therapeutic agents is chiefly determined by their side effects and resistance profiles.
“The efficacy of repurposed therapeutic agents is chiefly determined by their side effects and resistance profiles.345”
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Cites
Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012
Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., Parkin, D. M., Forman, D., & Bray, F. (2015) · International Journal of Cancer · doi:10.1002/ijc.29210 · Cited by 28,766 · see citing works
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
Ferlay, J., Shin, H., Bray, F., Forman, D., Mathers, C. D., & Parkin, D. M. (2010) · International Journal of Cancer · doi:10.1002/ijc.25516 · Cited by 21,271 · see citing works
MicroRNA signatures in human cancers
Calin, G. A., & Croce, C. M. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1997 · Cited by 7,592 · see citing works
Nanoparticle therapeutics: an emerging treatment modality for cancer
Davis, M. E., Chen, Z., & Shin, D. M. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2614 · Cited by 4,233 · see citing works
Impact of Nanotechnology on Drug Delivery
Farokhzad, O. C., & Langer, R. (2009) · ACS Nano · doi:10.1021/nn900002m · Cited by 3,364 · see citing works
The dawning era of polymer therapeutics
Duncan, R. (2003) · Nature Reviews Drug Discovery · doi:10.1038/nrd1088 · Cited by 3,273 · see citing works
Functional Nanomaterials for Phototherapies of Cancer
Cheng, L., Wang, C., Feng, L., Yang, K., & Liu, Z. (2014) · Chemical Reviews · doi:10.1021/cr400532z · Cited by 2,432 · see citing works
Imaging in the era of molecular oncology
Weissleder, R., & Pittet, M. J. (2008) · Nature · doi:10.1038/nature06917 · Cited by 2,365 · see citing works
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164 · see citing works
Hyperthermia in combined treatment of cancer
Wust, P., Hildebrandt, B., Sreenivasa, G., Rau, B., Gellermann, J., Riess, H. B., FELIX, R., & Schlag, P. (2002) · The Lancet Oncology · doi:10.1016/s1470-2045(02)00818-5 · Cited by 2,002 · see citing works
Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Okines, A. F. C., Verheij, M., Allum, W., Cunningham, D., & Cervantes, A. M. R. (2010) · Annals of Oncology · doi:10.1093/annonc/mdq164 · Cited by 1,300 · see citing works
Study on antimicrobial activity of chitosan with different molecular weights
Lian-ying, Z., & Zhu, J. (2003) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2003.07.009 · Cited by 1,031 · see citing works
Gastric cancer: epidemiology, prevention, classification, and treatment
Sitarz, R., Skierucha, M., Mielko, J., Offerhaus, G. J. A., Maciejewski, R., & Polkowski, W. P. (2018) · Cancer Management and Research · doi:10.2147/cmar.s149619 · Cited by 1,028 · see citing works
Hertzberg, R., Caranfa, M. J., & Hecht, S. M. (1989) · Biochemistry · doi:10.1021/bi00437a018 · Cited by 552 · see citing works
Wang, H., Khor, T., Shu, L.-M., Su, Z.-C., Fuentes, F., Lee, J.-H., & Kong, A. (2012) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/187152012803833026 · Cited by 532 · see citing works
Fabrication of gold nanoparticles for targeted therapy in pancreatic cancer
Patra, C. R., Bhattacharya, R., Mukhopadhyay, D., & Mukherjee, P. (2009) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2009.11.007 · Cited by 464 · see citing works
The Role of Absorption, Distribution, Metabolism, Excretion and Toxicity in Drug Discovery
Lin, J., Sahakian, D. C., de Morais, S., Xu, J. J., Polzer, R. J., & Winter, S. M. (2003) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026033452096 · Cited by 329 · see citing works
Nanoparticle therapeutics: an emerging treatment modality for cancer
Davis, M. E., Chen, Z., & Shin, D. M. (2009) · Co-Published with Macmillan Publishers Ltd, UK eBooks · doi:10.1142/9789814287005_0025 · Cited by 324 · see citing works
Enzymic preparation of water-soluble chitosan and their antitumor activity
Qin, C., Du, Y., Xiao, L., Li, Z., & Gao, X. (2002) · International Journal of Biological Macromolecules · doi:10.1016/s0141-8130(02)00064-8 · Cited by 308 · see citing works
Gold Nanoparticle-Mediated Photothermal Therapy: Current Status and Future Perspective
Hwang, S., Nam, J., Jung, S., Song, J., Doh, H., & Kim, S. (2014) · Nanomedicine · doi:10.2217/nnm.14.147 · Cited by 284 · see citing works
Graphene as Cancer Theranostic Tool: Progress and Future Challenges
Orecchioni, M., Cabizza, R., Bianco, A., & Delogu, L. G. (2015) · Theranostics · doi:10.7150/thno.11387 · Cited by 274 · see citing works
Recent progress on nanoparticle-based drug delivery systems for cancer therapy
Xin, Y., Yin, M., Zhao, L., Meng, F., & Luo, L. (2017) · Cancer Biology and Medicine · doi:10.20892/j.issn.2095-3941.2017.0052 · Cited by 265 · see citing works
Thermoresponsive magnetic composite nanomaterials for multimodal cancer therapy
Purushotham, S., & Ramanujan, R. V. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2009.07.004 · Cited by 256 · see citing works
Kato, K., Chin, K., Yoshikawa, T., Yamaguchi, K., Tsuji, Y., Esaki, T., Sakai, K., Kimura, M., Hamaguchi, T., Shimada, Y., et al. (2012) · Investigational New Drugs · doi:10.1007/s10637-011-9709-2 · Cited by 237 · see citing works
Ishigami, H., Kitayama, J., Kaisaki, S., Hidemura, A., Kato, M., Otani, K., Kamei, T., Soma, D., Miyato, H., Yamashita, H., et al. (2009) · Annals of Oncology · doi:10.1093/annonc/mdp260 · Cited by 230 · see citing works
Zhu, L., Ma, J., Jia, N., Zhao, Y., & Shen, H. (2008) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2008.07.020 · Cited by 211 · see citing works
Nagarwal, R. C., Kumar, R., & Pandit, J. K. (2012) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2012.08.008 · Cited by 195 · see citing works
Sun, L. N., Chen, Y., Zhou, Y., Guo, D., Fan, Y., Guo, F.-Y., Zheng, Y., & Chen, W. (2017) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2017.04.002 · Cited by 193 · see citing works
Bakhtiary, Z., Saei, A. A., Hajipour, M. J., Raoufi, M., Vermesh, O., & Mahmoudi, M. (2015) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2015.10.019 · Cited by 180 · see citing works
Lyu, Y., Cui, D. M., Sun, H., Miao, Y., Duan, H., & Pu, K. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201705543 · Cited by 175 · see citing works
Nanotechnology for the delivery of phytochemicals in cancer therapy
Xie, J., Yang, Z., Zhou, C., Zhu, J., Lee, R. J., & Teng, L. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.04.002 · Cited by 171 · see citing works
Liang, S., Li, C., Zhang, C., Chen, Y., Xu, L. G., Bao, C., Wang, X., Liu, G., Zhang, F., & Cui, D. (2015) · Theranostics · doi:10.7150/thno.11632 · Cited by 167 · see citing works
Shi, H., Sun, Y., Yan, R., Liu, S., Zhu, L., Liu, S., Feng, Y., Wang, P., He, J., Zhou, Z., et al. (2019) · Nano Letters · doi:10.1021/acs.nanolett.8b04179 · Cited by 166 · see citing works
Qi, L.-F., Xu, Z., Li, Y., Jiang, X., & Han, X. (2005) · Europe PMC (PubMed Central) · doi:10.3748/wjg.v11.i33.5136 · Cited by 160 · see citing works
Co-delivery with nano-quercetin enhances doxorubicin-mediated cytotoxicity against MCF-7 cells
Minaei, A., Sabzichi, M., Ramezani, F., Hamishehkar, H., & Samadi, N. (2016) · Molecular Biology Reports · doi:10.1007/s11033-016-3942-x · Cited by 136 · see citing works
Anticancer function of polyinosinic-polycytidylic acid
Cheng, Y., & Xu, F. (2010) · Cancer Biology & Therapy · doi:10.4161/cbt.10.12.13450 · Cited by 131 · see citing works
Confocal endomicroscopy for the diagnosis of gastric cancer in vivo
Kitabatake, S., Niwa, Y., Miyahara, R., Ohashi, A., Matsuura, T., Iguchi, Y., Shimoyama, Y., Nagasaka, T., Maeda, O., Ando, T., et al. (2006) · Endoscopy · doi:10.1055/s-2006-944855 · Cited by 129 · see citing works
Cui, D., Zhang, C., Liu, B., Shu, Y., Du, T., Shu, D., Wang, K., Dai, F., Liu, Y., Li, C., et al. (2015) · Scientific Reports · doi:10.1038/srep10726 · Cited by 126 · see citing works
Fang, Z., Li, X., Xu, Z., Du, F., Wang, W., Shi, R., & Gao, D. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s213974 · Cited by 117 · see citing works
Modulation of camptothecin analogs in the treatment of cancer: a review
Kehrer, D. F. S., Soepenberg, O., Loos, W. J., Verweij, J., & Sparreboom, A. (2001) · Anti-Cancer Drugs · doi:10.1097/00001813-200102000-00002 · Cited by 117 · see citing works
Zhang, H., Li, X., Ding, J., Xu, H., Dai, X., Hou, Z., Zhang, K., Sun, K., & Sun, W. (2012) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2012.11.034 · Cited by 110 · see citing works
Fang, J., Zhang, S., Xue, X., Zhu, X., Song, S., Wang, B., Jiang, L., Qin, M., Liang, H., & Gao, L. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s170862 · Cited by 110 · see citing works
Xu, S., Cui, F., Huang, D., Zhang, D., Zhu, A., Sun, X., Cao, Y., Ding, S., Wang, Y., Gao, E., et al. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s175340 · Cited by 106 · see citing works
Advancement in multifunctional nanoparticles for the effective treatment of cancer
Rahman, M., Ahmad, M. Z., Kazmi, I. A., Akhter, S., Afzal, M., Gupta, G., Ahmed, F. J., & Anwar, F. (2012) · Expert Opinion on Drug Delivery · doi:10.1517/17425247.2012.668522 · Cited by 97 · see citing works
Cytotoxicity and antibacterial activity of gold-supported cerium oxide nanoparticles
Chen, B., Babu, K. S., Anandkumar, M., Tsai, T. Y., Kao, T. H., & Inbaraj, B. S. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s70087 · Cited by 95 · see citing works
Nanotechnology-Based Precision Tools for the Detection and Treatment of Cancer
Stegh, A. H., Petrosko, S. H., Meade, T. J., & Mirkin, C. A. (2015) · Cancer treatment and research · doi:10.1007/978-3-319-16555-4 · Cited by 93 · see citing works
Li, X., Lu, X., Xu, H., Zhu, Z., Yin, H., Qian, X., Li, R., Jiang, X., & Liu, B. (2011) · Molecular Pharmaceutics · doi:10.1021/mp2002736 · Cited by 92 · see citing works
Ahmad, M. Z., Alkahtani, S. A., Akhter, S., Ahmad, F. J., Ahmad, J., Akhtar, M. S., Mohsin, N., & Abdel‐Wahab, B. A. (2015) · Journal of drug targeting · doi:10.3109/1061186x.2015.1055570 · Cited by 87 · see citing works
The application of nanoparticles in diagnosis and theranostics of gastric cancer
Li, R., Liu, B., & Gao, J. (2016) · Cancer Letters · doi:10.1016/j.canlet.2016.10.032 · Cited by 84 · see citing works
Jiang, H., Geng, D., Liu, H., Li, Z., & Cao, J. (2016) · Drug Delivery · doi:10.1080/10717544.2016.1217954 · Cited by 83 · see citing works
Ried, K., Eng, P., & Sali, A. (2017) · Advances in Cancer Prevention · doi:10.4172/2472-0429.1000123 · Cited by 82 · see citing works
Wang, J., Zhu, R., Sun, X., Wang, T., Liu, H., & Wang, S. (2014) · International Journal of Nanomedicine · doi:10.2147/ijn.s64103 · Cited by 81 · see citing works
Zhang, J., Zhao, T., Han, F., Hu, Y., & Li, Y. (2019) · Journal of Nanobiotechnology · doi:10.1186/s12951-019-0515-x · Cited by 80 · see citing works
Xu, L., Qu, C.-Y., Zhou, M., Chen, Y., Chen, M., & Shen, F. (2015) · International Journal of Nanomedicine · doi:10.2147/ijn.s83211 · Cited by 72 · see citing works
Li, Y., Zhang, H., & Xin, L. (2018) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-018-2678-5 · Cited by 70 · see citing works
Wang, K., Ruan, J., Qian, Q., Song, H., Bao, C., Zhang, X., Kong, Y., Zhang, C., Hu, G., Ni, J., et al. (2011) · Journal of Nanobiotechnology · doi:10.1186/1477-3155-9-23 · Cited by 69 · see citing works
Saito, T., Wada, H., Yamasaki, M., Miyata, H., Nishikawa, H., Sato, E., Kageyama, S., Shiku, H., Mori, M., & Doki, Y. (2014) · Vaccine · doi:10.1016/j.vaccine.2014.09.002 · Cited by 67 · see citing works
Shi, J., Liu, S., Yu, Y., He, C., Tan, L., & Shen, Y. (2019) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2019.04.042 · Cited by 64 · see citing works
Li, J., Hou, X., Bao, H., Sun, L., Tang, B., Wang, F., Wang, X., & Gu, M. (2013) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.34871 · Cited by 62 · see citing works
Cui, F., Li, R., Liu, Q., Wu, P.-Y., Hu, W., Yue, G., Ding, H., Li-xia, Y., Qian, X.-P., & Liu, B.-R. (2013) · Cancer Letters · doi:10.1016/j.canlet.2013.12.002 · Cited by 58 · see citing works
Yang, S., Li, J., Wang, S.-M., Yong, X., Tang, B., Jie, M., Dong, H. F., Yang, X., & Xiao, Y. (2016) · International Journal of Nanomedicine · doi:10.2147/ijn.s103648 · Cited by 55 · see citing works
Molecular mechanisms and theranostic potential of miRNAs in drug resistance of gastric cancer
Yang, W., Ma, J., Zhou, W. J., Cao, B., Xin Min, Z. H. O. U., Yang, Z., Zhang, H., Zhao, Q., Fan, D., & Hong, L. (2017) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1389900 · Cited by 52 · see citing works
Li, C., Wang, Y., Zhang, H., Li, M., Zhu, Z., & Xue, Y. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s193064 · Cited by 52 · see citing works
Yoshida, M., Watanabe, Y., Sato, M., Maehara, T., Aono, H., Naohara, T., Hirazawa, H., Horiuchi, A., Yukumi, S., Sato, K., et al. (2009) · International Journal of Cancer · doi:10.1002/ijc.24864 · Cited by 51 · see citing works
Cancer Targeted Magic Bullets for Effective Treatment of Cancer
Aneja, P., Rahman, M., Beg, S., Aneja, S., Dhingra, V., & Chugh, R. (2015) · Recent Patents on Anti-Infective Drug Discovery · doi:10.2174/1574891x10666150415120506 · Cited by 47 · see citing works
Bao, C., Conde, J., Curtin, J. F., Artzi, N., Tian, F., & Cui, D. (2015) · Scientific Reports · doi:10.1038/srep12297 · Cited by 46 · see citing works
Hu, N., Yin, J., Ji, Z., Hong, Y., Wu, P., Bian, B., Song, Z., Li, R., Liu, Q., & Wu, F. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000485955 · Cited by 46 · see citing works
Hu, Y., Wang, Z., Qiu, Y., Liu, Y., Ding, M., & Zhang, Y. (2019) · Journal of drug targeting · doi:10.1080/1061186x.2019.1610766 · Cited by 45 · see citing works
Fernandes, E., Ferreira, D., Peixoto, A., Freitas, R., Relvas‐Santos, M., Palmeira, C., Martins, G., Barros, A., Santos, L. L., Sarmento, B. F. C. C., et al. (2019) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2019.118646 · Cited by 43 · see citing works
Cai, J., Qian, K., Zuo, X., Yue, W., Bian, Y., Yang, J. D., Wei, J., Zhao, W., Qian, H., & Li, R. (2019) · Journal of Biomaterials Applications · doi:10.1177/0885328219837683 · Cited by 41 · see citing works
Qu, J., Hou, Z., Han, Q., Zhang, C., Tian, Z., & Zhang, J. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.08.013 · Cited by 39 · see citing works
Yang, J., Li, Z.-H., Zhou, J.-J., Chen, R., Cheng, L.-Z., Zhou, Q.-B., & Yang, L. (2010) · 癌症：英文版 · doi:10.5732/cjc.009.10541 · Cited by 36 · see citing works
Yang, F., Li, A., Liu, H., & Zhang, H. (2018) · Drug Design Development and Therapy · doi:10.2147/dddt.s176879 · Cited by 35 · see citing works
Song, Z., Liang, X., Wang, Y., Han, H., Yang, J., Fang, X., & Li, Q. (2019) · Biomaterials Science · doi:10.1039/c8bm01385c · Cited by 34 · see citing works
Rahman, M., Beg, S., Aziz, A. N., & Swain, S. (2014) · Current Nanomedicine · doi:10.2174/18779123113036660002 · Cited by 34 · see citing works
Yang, F., Zheng, Z., Zheng, L., Qin, J., Li, H., Xue, X., Gao, J., & Fang, G.-E. (2018) · OncoTargets and Therapy · doi:10.2147/ott.s182437 · Cited by 34 · see citing works
Cheng, C., Chang, Ho, Peng, Chang, Mai, Chen, Luo, & Huang (2013) · International Journal of Nanomedicine · doi:10.2147/ijn.s42003 · Cited by 31 · see citing works
Czupryna, J., & Tsourkas, A. (2006) · Cancer Biology & Therapy · doi:10.4161/cbt.5.12.3730 · Cited by 30 · see citing works
Anticancer effect of YWHAZ silencing via inducing apoptosis and autophagy in gastric cancer cells
Guo, F., Jiao, D., Sui, G., SUN, L. N., Gao, Y. J., Fu, Q., & Jin, C. (2018) · Neoplasma · doi:10.4149/neo_2018_170922n603 · Cited by 28 · see citing works
Takashima, A., Boku, N., Kato, K., Nakamura, K., Mizusawa, J., Fukuda, H., Shirao, K., Shimada, Y., & Ohtsu, A. (2013) · Gastric Cancer · doi:10.1007/s10120-013-0309-z · Cited by 23 · see citing works
Shi, J., Gao, P., Song, Y., Chen, X., Li, Y., Zhang, C., Wang, H., & Wang, Z. (2017) · Scientific Reports · doi:10.1038/s41598-017-05464-0 · Cited by 20 · see citing works
Zhang, K., Du, X., Yu, K., Zhang, K., & Zhou, Y. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5388 · Cited by 15 · see citing works
Lodhi, M. S., & Samra, Z. Q. (2019) · Preparative Biochemistry & Biotechnology · doi:10.1080/10826068.2019.1643736 · Cited by 13 · see citing works
Nanomedicine Drug Delivery System
Somwanshi, S. B., Dolas, R. T., Siddheshwar, S. S., Merekar, A. N., Godge, R. K., & Pattan, S. R. (2013) · Asian journal of biomedical and pharmaceutical sciences · doi:10.15272/ajbps.v3i22.314 · Cited by 11 · see citing works
Magnetic nanoparticles for treatment of gastric cancer
Jiang, X., & Chan, H. C. (2012) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2011.07031.x · Cited by 7 · see citing works
Nanoparticles to Deal with Gastric Cancer
Kuddus, S. A. (2017) · Journal of Gastrointestinal Cancer and Stromal Tumors · doi:10.4172/2572-4126.1000112 · Cited by 5 · see citing works
Flagged first, then by citations
4 of the 90 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Drug repurposing for cancer therapy
Xia, Y., Sun, M., Huang, H., & Jin, W.-L. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01808-1 · Cited by 443 · see citing works
Mbugua, S. N., Sibuyi, N. R. S., Njenga, L. W., Odhiambo, R. A., Wandiga, S. O., Meyer, M., Lalancette, R. A., & Onani, M. O. (2020) · ACS Omega · doi:10.1021/acsomega.0c00360 · Cited by 125 · see citing works
The development and progress of nanomedicine for esophageal cancer diagnosis and treatment
Li, X., Chen, L., Luan, S., Zhou, J., Xiao, X., Yang, Y., Mao, C., Fang, P., Chen, L.-Q., Zeng, X., et al. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.01.007 · Cited by 98 · see citing works
LncRNA SNHG5: A new budding star in human cancers
Li, Y.-H., Hu, Y., Wang, S.-C., Yang, L., & Chen, D. (2020) · Gene · doi:10.1016/j.gene.2020.144724 · Cited by 76 · see citing works
Polymer-Based Nanosystems—A Versatile Delivery Approach
Niculescu, A.-G., & Grumezescu, A. M. (2021) · Materials · doi:10.3390/ma14226812 · Cited by 76 · see citing works
Research trends on nanomaterials in gastric cancer: a bibliometric analysis from 2004 to 2023
Ling, L., Ouyang, Y., & Hu, Y. (2023) · Journal of Nanobiotechnology · doi:10.1186/s12951-023-02033-8 · Cited by 69 · see citing works
Drug Delivery Systems of Natural Products in Oncology
Colone, M., Calcabrini, A., & Stringaro, A. (2020) · Molecules · doi:10.3390/molecules25194560 · Cited by 54 · see citing works
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05498-9 · Cited by 55 · see citing works
Biomimetic nanoarchitecturing: A disguised attack on cancer cells
Jha, A., Nikam, A. N., Kulkarni, S., Mutalik, S. P., Pandey, A. P., Hegde, M. M., Rao, B. S. S., & Mutalik, S. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.12.005 · Cited by 48 · see citing works
Rahman, M. M., Islam, F., Mim, S. A., Khan, M. S., Islam, M. R., Haque, M. A., Mitra, S., Emran, T. B., & Rauf, A. (2022) · Journal of Nanomaterials · doi:10.1155/2022/4217529 · Cited by 45 · see citing works
RetractedNanoparticle-Mediated Hyperthermia and Cytotoxicity Mechanisms in Cancer
Bala, V.-M., Lampropoulou, D. I., GRAMMATIKAKI, S., Kouloulias, V., Lаgopati, N., Aravantinos, G., & Gazouli, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010296 · Cited by 35 · see citing works
Zeynalzadeh, E., Khodadadi, E., Khodadadi, E., Ahmadian, Z., Kazeminava, F., Rasoulzadehzali, M., & Kafil, H. S. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35562 · Cited by 27 · see citing works
Gulla, S., Reddy, V. C., Araveti, P. B., Lomada, D., Srivastava, A., Reddy, M. C., & Reddy, K. R. (2021) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2021.131556 · Cited by 27 · see citing works
Applications of nanomaterials for gastrointestinal tumors: A review
Kanaoujiya, R., Porwal, D., & Srivastava, S. (2022) · Frontiers in Medical Technology · doi:10.3389/fmedt.2022.997123 · Cited by 26 · see citing works
Application of iron oxide nanoparticles in the diagnosis and treatment of leukemia
Wang, Y., Yang, Y. T., Zheng, X., Shi, J., Zhong, L., Duan, X., & Zhu, Y. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1177068 · Cited by 25 · see citing works
Du, W., Feng, K., Li, C., Li, S., Abidin, Z. U., Yin, H., & Chen, S. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.105192 · Cited by 19 · see citing works
Arnold, A. M., Bradley, A. M., Taylor, K., Kennedy, Z. C., & Omberg, K. M. (2022) · Health Security · doi:10.1089/hs.2022.0014 · Cited by 16 · see citing works
Nomograms Involving HER2 for Predicting Lymph Node Metastasis in Early Gastric Cancer
Mei, Y., Wang, S., Feng, T., Yan, M., Yuan, F., Zhu, Z., Li, T. X., & Zhu, Z. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.781824 · Cited by 16 · see citing works
Emerging Role of Neutrophil Extracellular Traps in Gastrointestinal Tumors: A Narrative Review
Zhang, Y., Song, J., Zhang, Y., Li, T., Peng, J., Zhou, H., & Zong, Z. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010334 · Cited by 15 · see citing works
Rayhan, M. A., Hossen, M. S., Niloy, M. S., Bhuiyan, M. H., Paul, S., & Shakil, M. S. (2021) · Symmetry · doi:10.3390/sym13060974 · Cited by 14 · see citing works
Yu, Z., Lan, J., Li, W., Jin, L., Qi, F., Chen, Y., & Zhu, H. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/2775433 · Cited by 13 · see citing works
RetractedBera, B., Mondal, S., Mandal, S., Saha, K. D., & Mondal, T. K. (2023) · Applied Organometallic Chemistry · doi:10.1002/aoc.7185 · Cited by 13 · see citing works
Bera, B., Mondal, S., Gharami, S., Naskar, R., Saha, K. D., & Mondal, T. K. (2022) · New Journal of Chemistry · doi:10.1039/d2nj01894b · Cited by 13 · see citing works
Xenograft and organoid models in developing precision medicine for gastric cancer (Review)
Xu, J., Yu, B., Wang, F., & Yang, J. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5629 · Cited by 11 · see citing works
Beyond DNA-targeting in Cancer Chemotherapy. Emerging Frontiers - A Review
Mbugua, S. N., Njenga, L. W., Odhiambo, R. A., Wandiga, S. O., & Onani, M. O. (2020) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026620666200819160213 · Cited by 11 · see citing works
Silva-Abreu, M., Miralles, E., Kamma‐Lorger, C. S., Espina, M., García, M. L., & Calpena, A. C. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13111751 · Cited by 9 · see citing works
Chaudhary, K. R., Banik, P., & Singh, K. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.104859 · Cited by 7 · see citing works
Docetaxel-loaded pH/ROS dual-responsive nanoparticles for the targeted treatment of gastric cancer
Wu, J., Du, K., Bao, Y., Xiong, M., Chen, J., Luo, Z., Zhang, D., & Shi, Y. (2025) · Cancer Nanotechnology · doi:10.1186/s12645-025-00308-3 · Cited by 7 · see citing works
Habibzadeh, S. Z., Salehzadeh, A., Moradi–Shoeili, Z., & Shandiz, S. A. S. (2022) · Inorganic and Nano-Metal Chemistry · doi:10.1080/24701556.2021.2025074 · Cited by 7 · see citing works
Application and development of nanomaterials in the diagnosis and treatment of esophageal cancer
Xiao, Q., Zhang, Y., Zhao, A., Duan, Z., & Yao, J. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1268454 · Cited by 7 · see citing works
Sharma, P., Pal, D., Gill, A. R., Gupta, M., Goyal, S., Bansal, P., Sharma, U., Mathkor, D. M., Haque, S., Kaur, D., et al. (2024) · Medical Oncology · doi:10.1007/s12032-024-02587-z · Cited by 6 · see citing works
Liu, T., Gu, Y., Zhao, Y., & Li, Y. (2025) · Medical Oncology · doi:10.1007/s12032-025-02650-3 · Cited by 6 · see citing works
Li, G., Huo, D., Guo, N., Li, Y., Ma, H., Liu, L., Xie, H., Zhang, D., Qu, B., & Chen, X. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1106724 · Cited by 5 · see citing works
Li, D., Fan, Y., Liu, M., Huang, S., & Wang, S. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.104758 · Cited by 4 · see citing works
Lipid-based Nano-phytomedicines for Disease Treatment and Theranostic Applications
Ali, F., Khasimbi, S., & Ali, A. (2020) · Current Nanomedicine · doi:10.2174/2468187310999201023151700 · Cited by 4 · see citing works
Nanoparticles, a promising treatment for gastric cancer
Hua, D., Wu, X., Wu, Z., Fan, C., Wang, J., He, W. A., Deng, Y., Zhang, Y., Shu, H., Shen, M., et al. (2025) · Smart Materials in Medicine · doi:10.1016/j.smaim.2025.01.002 · Cited by 3 · see citing works
Nano-based approaches for diagnosis and therapy of gastric cancer
Rai, A., Rawat, S. S., Chopra, H., Singh, I., & Emran, T. B. (2023) · International Journal of Surgery · doi:10.1097/js9.0000000000000116 · Cited by 3 · see citing works
Liu, B.-N., Gao, X., & Piao, Y. (2024) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v16.i5.2181 · Cited by 3 · see citing works
Jaroniek, P., Brzeziński, M., Chmiela, M., & Gonciarz, W. (2025) · Scientific Reports · doi:10.1038/s41598-025-99004-w · Cited by 2 · see citing works
Yang, Y., Wang, C., Liu, S., & Zhang, Y. (2025) · International Journal of Pharmaceutics X · doi:10.1016/j.ijpx.2025.100335 · Cited by 2 · see citing works
Saeed, M., Alqahtani, T., Shmrany, H. A., Gupta, G., Goh, K. W., Sahebkar, A., & Kesharwani, P. (2026) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2026.2620601 · Cited by 1 · see citing works
Research advances in nanomaterials for gastric cancer: Diagnosis and treatment
Zhang, W., Zhou, X., Ma, K., Lao, Q., Wang, Q., & Zhang, P. (2026) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2026.102927 · Cited by 1 · see citing works
Karunakar, K. K., Philips, S., & Jayaprakash, N. (2026) · Discover Oncology · doi:10.1007/s12672-026-05497-w · Cited by 1 · see citing works
Progress in research of tumor biomarkers and molecular imaging probes for gastric cancer
Wang, X., Yao, D.-F., & Ren, G. (2024) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v32.i1.1 · Cited by 1 · see citing works
Pathare, D., & Haddad, S. (2023) · Journal of Student Research · doi:10.47611/jsrhs.v12i1.4459
Role of nanotechnology in forensic DNA analysis
Vajpayee, K., Paida, V., & Shukla, R. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-30128-5.00023-0
Nanotheranostics in gastrointestinal cancers
Prabhu, P. S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-34039-0.00006-8
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755924
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755930
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26409915
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755933
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755942
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26410019
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755921
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755945
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755927
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755939
Li, Y., Wang, Z., Gao, P., Cao, D., Dong, R., Zhu, M., Fei, Y., Zuo, X., & Cai, J. (2024) · Figshare · doi:10.6084/m9.figshare.26755918
Londhe, P. V., Londhe, M. V., Salunkhe, A., & Khot, V. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95543-0.00010-8
Marques, K. K. G., Formiga, A. L. D., de Souza, R. R. M., Castro, I. O., Alexandre, H. M. D. S., Ramalho, I. G. D. S., Pereira, É. R. M., Carvalho, L. M. M., Sobral, M. V., Júnior, F. H. X., et al. (2026) · Particle & Particle Systems Characterization · doi:10.1002/ppsc.202500226
Research Progress of Nanodelivery Platforms in the Diagnosis and Treatment of Esophageal Cancer
Sun, S., Huang, H., Hong, H., Lu, W., Qiu, L., Liu, S., Huang, S., Ye, K., Sun, J., Lai, G., et al. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s588613
Introduction to next-generation oncotherapeutics and evolution of cancer therapy
Krishnatray, H., Chaurasia, R., Bansal, H., Santoshi, S., Kumar, J., & Chourasia, M. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-44181-3.00010-2
- Authors
- Nagaraju, G. P., Srivani, G., Dariya, B., Chalikonda, G., Farran, B., Behera, S. K., Alam, A., & Kamal, M. A.
- Affiliations
- Emory University (US)
- Banasthali University (IN)
- Indian Council of Medical Research (IN)
- King Abdulaziz University (SA)
- Corresponding author
- Nagaraju, Ganji Purnachandra
- Kamal, Mohammad Amjad
- ORCID
- Venue
- Seminars in Cancer Biology
- Publisher
- Elsevier BV
- Published
- 2021-02
- Volume
- 69
- Pages
- 69-76
- ISSN
- 1044-579X (ISSN-L)
- OpenAlex
- W2999336257
- Cited by
- 62
- References
- 90
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 18 · 2023: 11 · 2022: 8 · 2021: 5 · 2020: 6
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Seminars in Cancer Biology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Gastric Cancer Management and Outcomes
- Keywords
- gastric cancer, nanoparticles, targeted drug delivery, multimodal imaging, nanomedicine, controlled drug release, cancer diagnosis, bioavailability
- MeSH terms
- Animals, Antineoplastic Agents, Biological Availability, Humans, Stomach Neoplasms, Drug Delivery Systems, Nanoparticles, Multimodal Imaging
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