The DOI matches its Crossref record; 222 of the 230 references it cites were found in a registry or an index.
Exercise training modulates adipokine dysregulations in metabolic syndrome
Open accessAbstract
Metabolic syndrome (MetS) is a cluster of risk factors for various metabolic diseases, and it is characterized by central obesity, dyslipidemia, hypertension, and insulin resistance. The core component for MetS is adipose tissue, which releases adipokines and influences physical health. Adipokines consist of pro and anti-inflammatory cytokines and contribute to various physiological functions. Generally, a sedentary lifestyle promotes fat accumulation and secretion of pro-inflammatory adipokines. However, regular exercise has been known to exert various beneficial effects on metabolic and cognitive disorders. Although the mechanisms underlying exercise beneficial effects in MetS are not fully understood, changes in energy expenditure, fat accumulation, circulatory level of myokines, and adipokines might be involved. This review article focuses on some of the selected adipokines in MetS, and their responses to exercise training considering possible mechanisms.
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“Although improvements in fitness and reductions in adiposity were recorded after 8 weeks of training”
From Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging (2025) · cites this paper as [76]
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“the acute cytokine response remained comparable, reflecting a similar per-exercise immune reaction despite physiological adaptations”
From Exercise-Induced Muscle–Fat Crosstalk: Molecular Mediators and Their Pharmacological Modulation for the Maintenance of Metabolic Flexibility in Aging (2025) · cites this paper as [76]
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Items 201–222 of 222
Cloning and characterization of the human lactoferrin receptor gene promoter
Jiang, R., & Lönnerdal, B. (2018) · BioMetals · doi:10.1007/s10534-018-0080-z · Cited by 15
Alonso‐Gómez, Á. M., Tojal‐Sierra, L., Frau, E. F., Goicolea‐Güemez, L., Uribarri, A. A., Portillo, M. P., Toledo, E., Schröder, H., Salas‐Salvadó, J., & Borau, F. A. (2018) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2018.12.010 · Cited by 15
Kouhestani, S., Zare, S., & Babaei, P. (2018) · Journal of Menopausal Medicine · doi:10.6118/jmm.2018.24.3.169 · Cited by 15
Shi, Z., Xu, M., Chen, X., Wang, J., Zhao, T., & Zha, D. (2020) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2020.104591 · Cited by 15
Nieman, D. C., Zwetsloot, K. A., Lomiwes, D. D., Meaney, M. P., & Hurst, R. D. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00431 · Cited by 13
Martins, M. S., Farinha, J. B., Benetti, C. B., Courtes, A. A., Duarte, T., da Silva, J. C. N., Duarte, M. M. M. F., Soares, F. A. A., & dos Santos, D. L. (2015) · PubMed · doi:10.3305/nh.2015.32.2.8696 · Cited by 10
Miyamoto, L., Yamane, M., Tomida, Y., Kono, M., Yamaoka, T., Kawasaki, A., Hatano, A., Tsuda, K., Xu, W., Ikeda, Y., et al. (2017) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b17-00316 · Cited by 10
Ghanbari–Niaki, A., Saeidi, A., Gharahcholo, L., Dehbaghi, K. M., Zarekookandeh, N., Ahmadian, M., Zouhal, H., & Hackney, A. C. (2019) · Science & Sports · doi:10.1016/j.scispo.2019.04.010 · Cited by 9
Babaei, P., Ghouroghchi, A. P., Damirchi, A., & Tehrani, B. S. (2015) · Cited by 8
Yamada, H., Suzuki, D., Kakei, M., Kusaka, I., Ishikawa, S., & Hara, K. (2016) · Journal of Metabolic Syndrome · doi:10.4172/2167-0943.1000215 · Cited by 8
Mir, E., Moazzami, M., Bijeh, N., Dokht, E. H., & Rahimi, N. (2020) · International Journal of Diabetes in Developing Countries · doi:10.1007/s13410-019-00790-7 · Cited by 7
Martínez, P. Y. O., López, J. A. H., Díaz, D. P., Trujillo, D. A. Z., & Teixeira, A. M. (2019) · Retos · doi:10.47197/retos.v0i35.62041 · Cited by 7
Effect of Diet Regimen on Serum Vaspin Level in Obese Diabetic Female Patients
Mansour, S. W., Tawfiq, M., Khalefa, A. A., Hadhoud, S., & El-Shorbgy, E. (2019) · Zagazig University Medical Journal · doi:10.21608/zumj.2019.10713.11170 · Cited by 6
Martínez, P. Y. O., López, J. A. H., Díaz, D. P., Trujillo, D. A. Z., & Teixeira, A. M. (2019) · Dialnet (Universidad de la Rioja) · Cited by 5
Zohmangaihi, D., Sharma, S., & Madhu, S. (2019) · doi:10.35248/2155-6156.19.10.822 · Cited by 5
(2015) · International Journal of Kinesiology and Sports Science · doi:10.7575/aiac.ijkss.v.3n.4p.40 · Cited by 5
Garcia, N. F., da Silva, C. P. V., Ferreira, M. J., Oharomari, L. K., Rocha, T., & de Moraes, C. (2016) · Motriz Revista de Educação Física · doi:10.1590/s1980-65742016000100002 · Cited by 4
Shahdadi, A., & Molaei, K. (2016) · Mediterranean Journal of Social Sciences · doi:10.5901/mjss.2016.v7n4s2p163 · Cited by 3
Nikseresht, M., Rajabi, H., & Nikseresht, A. (2015) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2
Green, J. S., Lowe, R. C., Pronk, N., JACOBSEN, D. J., Rohack, J. J., & Crouse, S. F. (2005) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200505001-02459 · Cited by 2
Serum Adipokines and Metabolic Syndrome Risk Factors in Hispanic Children
Peterson, J. M., Clark, W. A., Marrs, J., & Alamian, A. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.1037.5 · Cited by 1
Green, J. S., Lowe, R., Pronk, N., et al. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-200505001-02459 · Cited by 1
Flagged first, then by citations
8 of the 230 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Banu, 2019, Adiponectin level in type 2 diabetes and its complication–A review, J Pharmaceut Sci Res, 11, 1172
- Ahsan, 2017, Pathophysiological role of leptin for human health: a review, Pakistan J Food Sci, 27, 46
- Rashid, 2018, Role of adipokines and free fatty acids in insulin resistance-a review, Int J Adv Res Sci Eng, 7, 2115
- Cavalcante, 2017, Aerobic but not resistance exercise can induce inflammatory pathways via toll-like 2 and 4: a systematic review, Sports Med Open, 3, 42, 10.1186/s40798-017-0111-2 · DOI
Cited by
Sorted by citations
Adipose–Muscle Crosstalk in Age-Related Metabolic Disorders: The Emerging Roles of Adipo-Myokines
Fang, P., She, Y., Yu, M., Min, W., Shang, W., & Zhang, Z. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101829 · Cited by 62
Tero-Vescan, A., Degens, H., Matsakas, A., Ștefănescu, R., Ősz, B. E., & Slevin, M. (2025) · Pharmaceuticals · doi:10.3390/ph18081222 · Cited by 44
“Although improvements in fitness and reductions in adiposity were recorded after 8 weeks of training, the acute cytokine response remained comparable, reflecting a similar per-exercise immune reaction despite physiological adaptations [76].”
Saeidi, A., Saei, M. A., Mohammadi, B., Zarei, H. R. A., Vafaei, M., Mohammadi, A. S., Barati, M., Montazer, M., Razi, O., Kiyumi, M. H. A., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1141796 · Cited by 33
Understanding the Role of Adipokines in Cardiometabolic Dysfunction: A Review of Current Knowledge
Datta, S., Koka, S., & Boini, K. M. (2025) · Biomolecules · doi:10.3390/biom15050612 · Cited by 33
Tang, M., Su, Q., Duan, Y., Fu, Y., Liang, M., Pan, Y., Yuan, J., Wang, M., Pang, X., Ma, J., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-47073-0 · Cited by 29
Metadata
- Authors
- Babaei, P., & Hoseini, R.
- Affiliations
- Guilan University of Medical Sciences (IR)
- Razi University (IR)
- Corresponding author
- Babaei, Parvin
- Venue
- Sports Medicine and Health Science
- Publisher
- Elsevier BV
- Published
- 2022-03
- Volume
- 4
- Issue
- 1
- Pages
- 18-28
- ISSN
- 2666-3376 (ISSN-L)
- PMC
- PMC9219261
- OpenAlex
- W4205977718
- Cited by
- 52
- References
- 230
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 8 · 2023: 13 · 2022: 5
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Sports Medicine and Health Science (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology (medical) › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Keywords
- metabolic syndrome, exercise training, adipokines, adipose tissue, inflammation, insulin resistance, myokines, abdominal obesity, energy expenditure, fat deposition
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