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Cited by 298

The DOI matches its Crossref record; 187 of the 187 references it cites were found in a registry or an index.

The role of dendritic cells in cancer and anti-tumor immunity

Open access
Marciscano, Ariel E., Anandasabapathy, Niroshana·2021·Seminars in Immunology

Abstract

Dendritic cells (DC) are key sentinels of the host immune response with an important role in linking innate and adaptive immunity and maintaining tolerance. There is increasing recognition that DC are critical determinants of initiating and sustaining effective T-cell-mediated anti-tumor immune responses. Recent progress in immuno-oncology has led to the evolving insight that the presence and function of DC within the tumor microenvironment (TME) may dictate efficacy of cancer immunotherapies as well as conventional cancer therapies, including immune checkpoint blockade, radiotherapy and chemotherapy. As such, improved understanding of dendritic cell immunobiology specifically focusing on their role in T-cell priming, migration into tissues and TME, and the coordinated in vivo responses of functionally specialized DC subsets will facilitate a better mechanistic understanding of how tumor-immune surveillance can be leveraged to improve patient outcomes and to develop novel DC-targeted therapeutic approaches.

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Metadata

Authors
Marciscano, A. E., & Anandasabapathy, N.
Venue
Seminars in Immunology
Publisher
Elsevier BV
Published
2021-02
Volume
52
Pages
101481
ISSN
1044-5323 (ISSN-L)
OpenAlex
W3165170726
Cited by
298
References
187
FWCI
12.05
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The role of dendritic cells in cancer and anti-tumor immunity. https://app.cochat.ai/papers/10.1016/j.smim.2021.101481
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Marciscano, A. E., & Anandasabapathy, N. (2021). The role of dendritic cells in cancer and anti-tumor immunity. Seminars in Immunology. https://doi.org/10.1016/j.smim.2021.101481

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.