Evaluation of the packaging and encapsulation reliability in fully integrated, fully wireless 100 channel utah slant electrode array (usea): Implications for long term functionality
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The encapsulation and packaging reliability in fully integrated, fully wireless 100 channel Utah Slant Electrode Array (USEA)/integrated neural interface-recording version 5 (INI-R5) has been evaluated by monitoring the extended long term in-vitro functional stability and recording longevity. The INI encapsulated with 6-μm Parylene-C was immersed in phosphate buffer saline (PBS) at room temperature for a period of over 12 months. The USEA/INI-R5, while being soaked was powered and configured wirelessly through 2.765 MHz inductive link and the transmitted frequency shift keying (FSK) modulated radio-frequency (RF) (900 MHz Industrial, scientific, medical-ISM band) signal was also recorded wirelessly as a function of soak time. In order to test the long term recording ability, in-vitro wireless recording was performed in agarose for few channels. The full functionality and the ability of the electrodes to record artificial neural signals even after 12 months of PBS soak provides a measure of encapsulation reliability, the functional and recording stability in fully integrated wireless neural interface and potential usefulness for future chronic implants.
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USEA problems could be partly solved by making the device wireless.
“These problems could be partly solved by making the device wireless (Sharma et al., 2012).”
From Update on Peripheral Nerve Electrodes for Closed-Loop Neuroprosthetics (2018) · cites this paper as Sharma et al., 2012
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“These problems could be partly solved by making the device wireless (Sharma et al., 2012).”
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- Authors
- Sharma, A., Rieth, L., Tathireddy, P., Harrison, R., Oppermann, H., Klein, M., Töpper, M., Jung, E., Normann, R., Clark, G., & Solzbacher, F.
- Affiliations
- University of Utah (US)
- Fraunhofer Institute for Reliability and Microintegration (DE)
- Corresponding author
- Sharma, A.
- Venue
- Sensors and Actuators A Physical
- Publisher
- Elsevier BV
- Published
- 2012-12
- Volume
- 188
- Pages
- 167-172
- ISSN
- 0924-4247 (ISSN-L)
- PMC
- PMC3533439
- OpenAlex
- W2065610457
- Cited by
- 35
- References
- 14
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 4 · 2018: 3 · 2017: 4 · 2016: 3 · 2015: 3 · 2014: 4 · 2013: 3
- FWCI
- 0.93
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- Locations
- Sensors and Actuators A Physical (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Fraunhofer-Publica (Fraunhofer-Gesellschaft) (submittedVersion)
- Funders
- Johns Hopkins University
- Technische Universität Kaiserslautern
- National Institutes of Health (5r01ns064318-02)
- National Institute of Neurological Disorders and Stroke (R01-NS064318)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Physical Sciences › Engineering › Biomedical Engineering › Wireless Body Area Networks
- Keywords
- neural interfaces, wireless neural recording, parylene-C encapsulation, packaging reliability, chronic implantation, inductive power transfer, frequency shift keying, 900 MHz ISM band
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