The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Evaluation of incidence of cholelithiasis after bariatric surgery in subjects treated or not treated with ursodeoxycholic acid
Abstract
Background The use of ursodeoxycholic acid (UDCA) to prevent gallstone formation after gastric bypass (RYGB) is still debated. Furthermore, only 1 study has assessed the effectiveness of UDCA after sleeve gastrectomy (SG) with mitigated results. Objectives To compare the incidence of cholelithiasis (CL) between patients treated or not treated with UDCA after RYGB and SG. Setting University hospital, France. Methods Since January 2008, a postoperative ultrasound monitoring was scheduled for all patients without previous cholecystectomy who underwent bariatric surgery in our institution. Patients who underwent at least 1 ultrasound in the first postoperative year (±6 months) were included. We started to systematically prescribe UDCA (500 mg/d) for 6 months postoperatively, in February 2012 for RYGB (once or twice daily) and in October 2013 for SG (once daily). Results Mean follow-up was 13.0±3.4 months. The incidence of CL was 32.5% in the 117 nontreated RYGB and 25.5% in the 51 nontreated SG. It was reduced to 2.4% in the 42 SG treated once daily (P = .005), to 5.7% in the 87 RYGB with 250 mg twice daily (P Conclusion UDCA 500 mg once daily for 6 months is efficient to prevent CL 1 year after SG, but the twice-daily doses seem to be more effective after RYGB. The effectiveness of UDCA once daily after SG and the superiority of the twice-daily doses after RYGB should be confirmed with more patients and longer follow-up.
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“A lack of significant effects on gallstones was also reported in pregnant women taking part in a randomized study [81].”
From Excess Body Weight and Gallstone Disease (2021) · cites this paper as [81]
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Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2019.10.025 · Cited by 608
Mechanick, J. I., Apovian, C., Brethauer, S., Garvey, W. T., Joffe, A. M., Kim, J., Kushner, R. F., Lindquist, R., Pessah-Pollack, R., Seger, J., et al. (2019) · Endocrine Practice · doi:10.4158/gl-2019-0406 · Cited by 510
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Lim, R., Beekley, A., Johnson, D. C., & Davis, K. A. (2018) · Trauma Surgery & Acute Care Open · doi:10.1136/tsaco-2018-000219 · Cited by 248
Magouliotis, D. E., Tasiopoulou, V. S., Svokos, A. A., Svokos, K. A., Chatedaki, C., Sioka, E., & Zacharoulis, D. (2017) · Obesity Surgery · doi:10.1007/s11695-017-2924-y · Cited by 108
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Metadata
- Authors
- Coupaye, M., Calabrese, D., Sami, O., Msika, S., & Ledoux, S.
- Venue
- Surgery for Obesity and Related Diseases
- Publisher
- Elsevier BV
- Published
- 2017-04
- Volume
- 13
- Issue
- 4
- Pages
- 681-685
- ISSN
- 1550-7289
- Cited by
- 58
- References
- 1
- Language
- en
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