Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target
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After tissue injury, mesenchymal cells undergo profound metabolic changes to support energy-consuming functions such as proliferation and protein synthesis.
“Following tissue injury, mesenchymal cells undergo profound metabolic changes in order to facilitate energy consuming cellular functions such as proliferation and protein synthesis42.”
From Fibrosis: from mechanisms to medicines (2020) · cites this paper as [42]
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Fibrosis: from mechanisms to medicines
Henderson, N. C., Rieder, F., & Wynn, T. A. (2020) · Nature · doi:10.1038/s41586-020-2938-9 · Cited by 1,868 · see citing works
- Authors
- Schneider, R. K., Mullally, A., Dugourd, A., Peisker, F., Hoogenboezem, R., Van Strien, P. M. H., Bindels, E. M., Heckl, D., Büsche, G., Fleck, D., Müller-Newen, G., Wongboonsin, J., Ventura Ferreira, M., Puelles, V. G., Saez-Rodriguez, J., Ebert, B. L., Humphreys, B. D., & Kramann, R.
- Corresponding author
- Schneider, Rebekka K.
- Kramann, Rafael
- ORCID
- Venue
- Cell Stem Cell
- Publisher
- Elsevier BV
- Published
- 2018-08
- Volume
- 23
- Issue
- 2
- Pages
- 308-309
- ISSN
- 1875-9777 (ISSN-L)
- 1934-5909
- OpenAlex
- W2998643974
- Cited by
- 34
- References
- 0
- Citations by year
- 2026: 6 · 2025: 3 · 2024: 3 · 2023: 7 · 2022: 3 · 2021: 6 · 2020: 6
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell stem cell (publishedVersion)
- Funders
- European Hematology Association
- Topics
- Health Sciences › Medicine › Hematology › Myeloproliferative Neoplasms: Diagnosis and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Mesenchymal stem cell research
- Health Sciences › Medicine › Hematology › Hematopoietic Stem Cell Transplantation
- Keywords
- mesenchymal stem cells, bone marrow fibrosis, perivascular niche, bone marrow homeostasis, GANT61, Hedgehog signaling, cell therapy
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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