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Cited by 316

The DOI matches its Crossref record; 134 of the 134 references it cites were found in a registry or an index.

Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling

Open access
van Velthoven, Cindy T.J., Rando, Thomas A.·2019·Cell Stem Cell

Abstract

Stem cells can reside in a state of reversible growth arrest, or quiescence, for prolonged periods of time. Although quiescence has long been viewed as a dormant, low-activity state, increasing evidence suggests that quiescence represents states of poised potential and active restraint, as stem cells “idle” in anticipation of activation, proliferation, and differentiation. Improved understanding of quiescent stem cell dynamics is leading to novel approaches to enhance maintenance and repair of aged or diseased tissues. In this Review, we discuss recent advances in our understanding of stem cell quiescence and techniques enabling more refined analyses of quiescence in vivo.

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Research works printed but not linked: 3

  1. Gos, 2005, Cellular quiescence induced by contact inhibition or serum withdrawal in C3H10T1/2 cells, Cell Prolif., 38, 107, 10.1111/j.1365-2184.2005.00334.x · doi:10.1111/j.1365-2184.2005.00334.x
  2. Mendelsohn, 1962, Autoradiographic analysis of cell proliferation in spontaneous breast cancer of C3H mouse. III. The growth fraction, J. Natl. Cancer Inst., 28, 1015
  3. Yanez, 1989, Variation in the length of the lag phase following serum restimulation of mouse 3T3 cells, Cell Biol. Int. Rep., 13, 453, 10.1016/0309-1651(89)90140-9 · doi:10.1016/0309-1651(89)90140-9

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Metadata

Authors
van Velthoven, C. T. J., & Rando, T. A.
Venue
Cell Stem Cell
Publisher
Elsevier BV
Published
2019-02
Volume
24
Issue
2
Pages
213-225
ISSN
  • 1875-9777 (ISSN-L)
  • 1934-5909
OpenAlex
W2911631359
Cited by
316
References
134
FWCI
22.14
Type
journal article
Language
en
Open access
bronze
Licence
Funders
  • Glenn Foundation for Aging Research
  • NIH (P01 AG036695, TR01 AG047820, R01 AR073248, R37, AG023806)
  • Department of Veterans Affairs

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CoChat. (2026). Citation check: Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling. https://app.cochat.ai/papers/10.1016/j.stem.2019.01.001
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van Velthoven, C. T. J., & Rando, T. A. (2019). Stem Cell Quiescence: Dynamism, Restraint, and Cellular Idling. Cell Stem Cell. https://doi.org/10.1016/j.stem.2019.01.001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.