PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease
Oksanen, Minna, Petersen, Andrew J., Naumenko, Nikolay, Puttonen, Katja, Lehtonen, Šárka, Gubert Olivé, Max, Shakirzyanova, Anastasia, Leskelä, Stina, Sarajärvi, Timo, Viitanen, Matti, Rinne, Juha O., Hiltunen, Mikko, Haapasalo, Annakaisa, Giniatullin, Rashid, Tavi, Pasi, Zhang, Su-Chun, Kanninen, Katja M., Hämäläinen, Riikka H., Koistinaho, Jari·2017·Stem Cell Reports
Cited by (337)
Items 201–300 of 337
- Modelling neurodegenerative diseases in vitro: Recent advances in 3D iPSC technologiesElodie J. Siney, Ksenia Kurbatskaya, Shreyasi Chatterjee, Preeti Prasannan, Amritpal K. Mudher, Sandrine Willaime‐Morawek · 2018 · AIMS Cell and Tissue Engineering
- Induced Pluripotent Stem Cell-Derived Astroglia: A New Tool for Research Towards the Treatment of Alzheimer’s DiseaseRebecca Atkinson-Dell, Lisa Mohamet · 2019 · Advances in experimental medicine and biology
- Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease ModelingJing Sun, Xun Ma, Ho Ting Chu, Bo Feng, Rocky S. Tuan, Yangzi Jiang · 2019 · Frontiers in Bioengineering and Biotechnology
- Mitochondrial Function in Alzheimer’s Disease: Focus on AstrocytesLampinen, Riikka, Belaya, Irina, Boccuni, Isabella, Malm, Tarja, Kanninen, Katja M. · 2018 · Astrocyte - Physiology and Pathology
- Patient iPSC-astrocytes show transcriptional and functional dysregulation in schizophreniaMarja Koskuvi, Šárka Lehtonen, Kalevi Trontti, Meike Hedwig Keuters, Ying Chieh Wu, Hennariikka Koivisto, Anastasia Ludwig, L. M. Plotnikova, Pekka L. J. Virtanen, Noora Räsänen et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changesYing‐Chieh Wu, Šárka Lehtonen, Kalevi Trontti, Riitta Kauppinen, Pinja Kettunen, Ville Leinonen, Markku Laakso, Johanna Kuusisto, Mikko Hiltunen, Iiris Hovatta et al. · 2024 · Fluids and Barriers of the CNS
- Ghrelin is a signal to facilitate the utilization of fatty acids and save glucose by the liver, skeletal muscle, and adipose tissues in chicksXixi Song, Minghui Wang, Hongchao Jiao, Jingpeng Zhao, Xiaojuan Wang, Hai Lin · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
- Hexokinase and Glycolysis: Between Brain Cells Life and DeathLarissa Rodrigues Souza da Mata, L. Santos, Marcelo Cerqueira César · 2023 · Current Chemical Biology
- In vivo and ex vivo gene therapy for neurodegenerative diseases: a promise for disease modificationPouyan Ebrahimi, Elham Davoudi, Razieh Sadeghian, Amin Zaki Zadeh, Emran Razmi, Reza Heidari, Mohammad Hossein Morowvat, Issa Sadeghian · 2024 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Traffic-related diesel pollution particles impair the lysosomal functions of human iPSC-derived microgliaSohvi Ohtonen, Henna Jäntti, Luca Giudice, Ahmed Y. Mohamed, Anastasia Shakirzyanova, Táňa Závodná, Ilya N Belevich, Hong Yan, Angélica María Sabogal-Guáqueta, Liudmila Saveleva et al. · 2025 · Environment International
- Neuroglia in neurodegeneration: Alzheimer, Parkinson, and Huntington diseaseLim, Dmitry, Matute, Carlos, Cavaliere, Fabio, Verkhratsky, Alexei · 2025 · Handbook of Clinical Neurology
- Recent behavioral findings of pathophysiological involvement of lactate in the central nervous systemYuki Kambe · 2022 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Altered neuronal group 1 metabotropic glutamate receptor- and endoplasmic reticulum-mediated Ca2+ signaling in two rodent models of Alzheimer’s diseaseAidan Kaar, Megan P. Weir, Mark George Rae · 2024 · Neuroscience Letters
- Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer’s DementiaKousi, Maria, Boix, Carles, Park, Yongjin P., Mathys, Hansruedi, Sledzieski, Samuel, Peng, Zhuyu, Bennett, David A., Tsai, Li-Huei, Kellis, Manolis · 2022
- The metabolic reprogramming of lactate in the nervous systemYu Gu, Botao Zhang, Chunyan Lei, Yanjiao Guan, Binger Fan, Wenyan Xu, Ansong Jin, Qionghua Deng, Ruolong Xue, Xinglong Yang et al. · 2026 · Experimental Neurology
- Role of dysregulated calcium homeostasis in astrocytes in neurodegenerative disordersMaria Virtudes Sanchez-Mico, María Calvo-Rodríguez, Brian J. Bacskai · 2026 · Nature reviews. Neuroscience
- Mitochondrial dysfunction of induced pluripotent stem cells-based neurodegenerative disease modeling and therapeutic strategyHongmei Luo, Jia Li Xu, Danxia Huang, Yun-Qiang Chen, Yizhou Liu, Yajie Li, Hong Chen · 2022 · Frontiers in Cell and Developmental Biology
- The Essential Role of Astrocytes in Neurodegeneration and NeuroprotectionFederico López Couselo, Julieta Saba, Lila Carniglia, Daniela Durand, Mercedes Lasaga, Carla M. Caruso · 2023 · CNS & Neurological Disorders - Drug Targets
- In and out: Benchmarking in vitro, in vivo, ex vivo, and xenografting approaches for an integrative brain disease modeling pipelineMarlene F. Pereira, Reinald Shyti, Giuseppe Testa · 2024 · Stem Cell Reports
- From Neuronal Differentiation of iPSCs to 3D Neural Organoids: Modeling of Neurodegenerative DiseasesMatteo Bordoni, Valentina Fantini, Orietta Pansarasa, Cristina Cereda · 2019 · IntechOpen eBooks
- Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged MiceHenna Jäntti, Minna Oksanen, Pinja Kettunen, Stella Manta, Lionel Moulédous, Hennariikka Koivisto, Johanna Ruuth, Kalevi Trontti, Hiramani Dhungana, Meike Hedwig Keuters et al. · 2022 · Cells
- Deciphering the Forebrain Disorder in a Chicken Model of Cerebral HerniaYingfeng Tao, Xiaoliu Zhou, Xinting Zheng, Shijun Li, Chunyan Mou · 2020 · Genes
- The Potential of Induced Pluripotent Stem Cells to Treat and Model Alzheimer’s DiseaseJoseph M. Schulz · 2021 · Stem Cells International
- Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysisOliver Jonathan Ziff, Sarah Jolly, Jackie M. Casey, Lucy Granat, Satinder Samra, Núria Setó‐Salvia, Argyro Alatza, Leela Phadke, Benjamin Galet, Philippe Ravassard et al. · 2025 · Molecular Neurodegeneration
- Role Shift of Glial Cells from Physiology to Pathology in Alzheimer’s Disease: The Regulatory Impact of ExerciseRunze Liu, Qianting Deng, Li Gong, Luodan Yang · 2026 · Neuroscience Bulletin
- iPSCs-Derived Neurons and Brain Organoids from PatientsWanying Zhu, Lei Xu, Xinrui Li, Hao Hu, Shu-Ning Lou, Yan Liu · 2023 · Handbook of experimental pharmacology
- Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific MannerNoora Räsänen, Jari Tiihonen, Marja Koskuvi, Šárka Lehtonen, Nelli Jalkanen, Nelli Karmila, Isabelle Weert, Olli Vaurio, Ilkka Ojansuu, Markku Lähteenvuo et al. · 2024 · Biological Psychiatry Global Open Science
- Breaking Barriers in Huntington’s Disease Therapy: Focused Ultrasound for Targeted Drug DeliveryMohamed Mohsen Helal, Amna Ibrahim, Ahmad Beddor, Muataz Omar Kashbour · 2025 · Neurochemical Research
- Tri‐Culture System Reveals an Activation Cascade From Microglia Through Astrocytes to Neurons During NeuroinflammationH Kobayashi, Hiroshi Kato, Mitsuho Taniguchi, Setsu Endoh‐Yamagami · 2026 · Journal of Neurochemistry
- Putative Molecular Mechanisms Underpinning the Inverse Roles of Mitochondrial Respiration and Heme Function in Lung Cancer and Alzheimer’s DiseaseAtefeh Afsar, Zhang Li · 2024 · Biology
- hiPSC-based models to decipher the contribution of human astrocytes to Alzheimer’s disease and potential therapeuticsJulia TCW, Amaia M. Arranz · 2023 · Molecular Neurodegeneration
- In vitro engineered models of neurodegenerative diseasesZehra Gül Morçimen, Şeyma Taşdemir, Aylin Şendemir · 2024 · Biocell
- Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC ‐derived astrocytesRichard J. Elsworthy, Mattéa J. Finelli, Sarah Aqattan, Connor Dunleavy, Marianne C. King, Adele Ludlam, Marta A. Tarczyluk, S. Allen, Sophie Prosser, Rui Chen et al. · 2024 · Journal of Neurochemistry
- The Janus face of CaMKII: from memory consolidation to neurotoxic switch in Alzheimer’s diseaseLuhong Tang, Feng Liu, Xuefei Sun, Jiaoyan Yang, Yifang Liu, Xueting Pan, Liying Hao, Fan Lou, Jingyang Su · 2025 · Archives of Toxicology
- Modeling neurovascular dysfunction in Alzheimer’s disease using an isogenic brain-chip modelAndrew Nathanael Shen, Katelin S. Matazel, W. Drew Gill, Lorna C. Ewart, Randy S. Daughters, Héctor Rosas-Hernández · 2026 · Fluids and Barriers of the CNS
- Immortalized hippocampal astrocytes from 3xTg-AD mice, a new model to study disease-related astrocytic dysfunction: a comparative reviewLaura Tapella, Giulia Dematteis, Armando A. Genazzani, Massimiliano De Paola, Dmitry Lim · 2022 · Neural Regeneration Research
- Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neuronsKristina Xiao Liang, Atefeh Kianian, Anbin Chen, Cecilie Katrin Kristiansen, Yu Hong, Jessica Furriol, Lena Elise Høyland, Mathias Ziegler, Torbjørn Kråkenes, Charalampos Tzoulis et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Targeted Delivery Modalities in Combination with Biofunctionalized Metallic Nanoparticles (MNPs): Combating Amyloid PlaquesNishabh Kushwaha, Drishti Panjwani, Kshitija Akarte, Shruti Patel, Priyanka Ahlawat, Rajesh Kesarla, Mange Ram Yadav, Asha Patel · 2025 · Current Nanoscience
- Special characteristics of human astrocytes and their roles in brain homeostasisIlari Kousa, Karo Talvio, Ulla‐Kaisa Peteri, Maija L. Castrén · 2026 · Neuroscience Applied
- Presenilin-1 ΔE9 mutation associated sarcoplasmic reticulum leak alters [Ca2+]i distribution in human iPSC-derived cardiomyocytesNikolay V. Naumenko, Jussi T. Koivumäki, Olesia Lunko, Tomi Tuomainen, Robert S. Leigh, Mina Rabiee, Jalmari Laurila, Minna Oksanen, Šárka Lehtonen, Jari Koıstınaho et al. · 2024 · Journal of Molecular and Cellular Cardiology
- Glutamate Transporter 1 as a Novel Negative Regulator of Amyloid βPriyanka Sinha, Yuliia Turchyna, Shane Mitchell, Michael Sadek, Gokce Armagan, Florian Perrin, Masato Maesako, Oksana Berezovska · 2024 · Cells
- iPSC for modeling of metabolic and neurodegenerative disordersV. Valadez-Barba, Agustín Cota-Coronado, Carla P. Barragán-Álvarez, Eduardo Padilla‐Camberos, Nestor Emmanuel Diaz-Martinez · 2022 · Elsevier eBooks
- AmazonForest: In Silico Metaprediction of Pathogenic VariantsHelber Gonzales Almeida Palheta, Wanderson Gonçalves e Gonçalves, Leonardo Miranda Brito, Arthur Ribeiro dos Santos, Marlon dos Reis Matsumoto, Ândrea Ribeiro‐dos‐Santos, Gilderlânio Santana de Araújo · 2022 · Biology
- Advances in the Application of Induced Pluripotent Stem Cells in Alzheimer’s Disease and Parkinson's DiseaseYiran Xu, Shuxia Wang, Ping Zhu · 2022 · Current Stem Cell Research & Therapy
- Astrocyte Progenitors Derived From Patients With Alzheimer Disease Do Not Impair Stroke Recovery in MiceNelli‐Noora Välimäki, Abdulhameed Bakreen, Sara Häkli, Hiramani Dhungana, Meike Hedwig Keuters, Yannick Dunlop, Marja Koskuvi, Velta Keksa-Goldsteine, Minna Oksanen, Henna Jäntti et al. · 2022 · Stroke
- Applications of Induced Pluripotent Stem Cell-Derived Glia in Brain Disease Research and TreatmentZhiqi Yang, Mingyue Gong, Chuanyan Yang, Chunhai Chen, Kuan Zhang · 2023 · Handbook of experimental pharmacology
- Preparation of astrocytes by directed differentiation of pluripotent stem cells and somatic cell transdifferentiationHangjie Chen, Kang Zheng, Mengsheng S. Qiu, Junlin Yang · 2023 · Developmental Neurobiology
- Identification of the abnormalities in astrocytic functions as potential drug targets for neurodegenerative diseaseValtteri Syvänen, Jari Koıstınaho, Šárka Lehtonen · 2024 · Expert Opinion on Drug Discovery
- DHM/SERS reveals cellular morphology and molecular changes during iPSCs-derived activation of astrocytesXiaoya Bu, Liwei Yang, Xianxin Han, Shengde Liu, Xiaoxu Lü, Jianhui Wan, Xiao Zhang, Ping Tang, Weina Zhang, Liyun Zhong · 2024 · Biomedical Optics Express
- Cell culture research in aging and Alzheimer's disease: The strategic use/reuse of untreated controls and savings people's tax dollarsSudhir Kshirsagar, Md. Ariful Islam, Arubala P. Reddy, P. Hemachandra Reddy · 2025 · Journal of Alzheimer s Disease Reports
- Human induced pluripotent stem cell– based modeling of Alzheimer’s disease, a glial perspectiveXianwei Chen, Qingqiu Yang, Zhenqing Liu, Yanhong Shi · 2021 · Elsevier eBooks
- Finnish neuroscience from past to presentEsa R. Korpi, Dan Lindholm, Pertti Panula, Pentti J. Tienari, Matti Haltia · 2020 · European Journal of Neuroscience
- [Progress on loss-of-function hypothesis of presenilin-1 mutations in Alzheimer diseases].Min Yan, Xu Wang, Xihan Guo · 2020 · PubMed Central
- Recent Advances in NeurodegenerationAntonella Borreca · 2019 · IntechOpen eBooks
- Microglial amyloid beta clearance is driven by PIEZO1 channelsHenna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez‐Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Drug Discovery in Induced Pluripotent Stem Cell ModelsKyla Bourque, Nourhen Mnasri, Jace Jones-Tabah, Kimberly Martins-Cannavino, Terence E. Hébert · 2021 · Elsevier eBooks
- Presenilin mutations disrupt iron homeostasis to promote ferroptosis mediated neurodegeneration in Caenorhabditis elegansKerry C. Ryan, Jocelyn T. Laboy, Rabia Ashraf, Zahra Ashkavand, Isabel Jayasinghe, Kenneth R. Norman · 2025 · Redox Biology
- Using iPSC models to examine neuron–glia interactions in neurodegenerative diseasesDianne Marquez Lopez, Lois Keavey, Kathryn R. Bowles · 2026 · Bioscience Reports
- Promising Prospects for Human Cerebral Organoids to Advance Alzheimer's Disease ResearchVictoria López, Andreea Rosca, Isabel Liste, Patricia Mateos-Martínez, Raquel Coronel, Rosa González-Sastre, Sabela Martín-Benito, Victoria López · 2023 · Progress in Neurobiology
- hPSC-Derived Astrocytes at the Forefront of Translational Applications in Neurological DisordersVukasin M. Jovanovic, Kendall T. Mesch, Carlos A. Tristan · 2024 · Cells
- Alzheimer’s Disease from Modeling to Mechanism ResearchXiaoyan Sun, Weiqi Zhang · 2024 · Advances in neurobiology
- Neuroglia and brain energy metabolismUchenna I. Peter-Okaka, Detlev Boison · 2025 · Handbook of clinical neurology
- CDiP technology for reverse engineering of sporadic Alzheimer’s diseaseTakayuki Kondo, Yuichiro Yada, Takeshi Ikeuchi, Haruhisa Inoue · 2022 · Journal of Human Genetics
- Emerging Methods in Modeling Brain Development and Disease with Human Pluripotent Stem CellsGeorge E. Allen, Aaron S. Dhanda, Lisa M. Julian · 2022 · Methods in molecular biology
- Increased Mitochondrial Calcium Uptake and Concomitant Hyperactivity by Presenilin Loss Promotes mTORC1 Signaling to Drive NeurodegenerationKerry C. Ryan, Zahra Ashkavand, Shaarika Sarasija, Jocelyn T. Laboy, Rohan Samarakoon, Kenneth R. Norman · 2020 · Research Square
- Altered metabolic function induced by amyloid-beta oligomers and PSEN1-mutations in iPSC-derived astrocytesRichard J. Elsworthy, Mattéa J. Finelli, Sarah Aqattan, Connor Dunleavy, Marianne C. King, Adele Ludlam, S. L. Allen, S. Prosser, Robert E. Chen, Sandra Martínez‐Jarquín et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Astrocytes regulate neuronal network burst frequency through NMDA receptors species- and donor-specificallyNoora Räsänen, Jari Tiihonen, Marja Koskuvi, Šárka Lehtonen, Nelli Jalkanen, Nelli Karmila, Isabelle Weert, Olli Vaurio, Ilkka Ojansuu, Markku Lähteenvuo et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer’s disease through disrupted regulated intramembrane proteolysisOliver Jonathan Ziff, Sarah Jolly, Jackie M. Casey, Lucy Granat, Satinder K. Samra, Núria Setó‐Salvia, Argyro Alatza, Leela Phadke, Benjamin Galet, Philippe Ravassard et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- In vitro models for human neurogliaBas Lendemeijer, Femke M. S. de Vrij · 2025 · Handbook of clinical neurology
- Presenilin 1 E280A mutation induces dysfunctional astrocytic phenotype in menstrual stromal-derived astrocyte-like cellsNatalia Quiroz Correa, Miguel Mendivil‐Perez, Carlos Velez‐Pardo, Marlene Jiménez-Del-Río, Q. Quiroz-Correa · 2025 · Cellular and Molecular Life Sciences
- From scaffold to effector: reframing GFAP in neurodegenerationYong-Heng Lu, Xiuping Zhu, Song Li, Fucong Zhang, Chuan-Bin Cai, Mao Tian, Yuhang Zhu, Ling-Hui Zeng, Jun Tan, Yu Changyin et al. · 2026 · Journal of Advanced Research
- CRISPR Applications in Alzheimer’s Disease: From High-Throughput Genetic Screening to Precision Editing and CNS DeliveryYou Li, Shixin Ma, Teng Fei · 2026 · International Journal of Molecular Sciences
- Single-Nucleus Profiling Reveals a BBB Senescence Unit Driving AD Pathology in Human BrainYuanwei Zhang, Zhongman Jin, Ruizhen Rao, Linqiao Si, Zhiruo Zhang, Ruixia Ma, Yi Min, Junpu Mei, Zhen Yue, Xiaodong Fang et al. · 2026 · Molecular Neurobiology
- APP /Aβ Signaling Orchestrates Reactive Astrocyte Networks in Alzheimer's DiseaseGretsen Velezmoro Jáuregui, Sophie Coomes, Elizabeth Emmett, Alex Thatcher, Nicole Oyelakin, Mária Čarná, Jana Zelinková, Jan Novotný, Natalie Polakova, Tarun Kuruvilla et al. · 2026 · Journal of Neurochemistry
- Organoids: the third dimension of human brain development and diseaseGeorgia Kouroupi, Kanella Prodromidou, Florentia Papastefanaki, Era Taoufik, Rebecca Matsas · 2021 · The International Journal of Developmental Biology
- Effects of oligotrophication on fish growth: Insights from a mesocosm experimentJuliana Déo Dias, Nadson Ressyé Simões, Cláudia Cósta Bonecker, Ângelo Antônio Agostinho · 2025 · Limnology and Oceanography
- Identifying maximally informative signal-aware representations of single-cell data using the information bottleneckSerafima Dubnov, Zoe Piran, Amit Alper, Adi Yefroimsky, Hermona Soreq, Mor Nitzan · 2026 · Cell Systems
- Human and mouse iPSC-derived astrocyte subtypes reveal vulnerability in Vanishing White MatterPrisca S. Leferink, Stephanie Dooves, Anne E.J. Hillen, Kyoko Watanabe, Gerbren Jacobs, Lisa Gasparotto, Paulien Cornelissen‐Steijger, Marjo S. van der Knaap, Vivi Majella Heine · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Human iPSC-derived Astrocytes Transplanted into the Mouse Brain Display three Morphological Responses to Amyloid-β PlaquesPranav Preman, Julia TCW, Sara Calafate, An Snellinx, María Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison Goate, Bart De Strooper et al. · 2020 · Research Square
- Alzheimer’s disease alters astrocytic functions related to neuronal support and transcellular internalization of mitochondriaRiikka Lampinen, Irina Belaya, Liudmila Saveleva, Jeffrey R. Liddell, Dzhessi Rait, Mikko T. Huuskonen, Raisa Giniatullina, Annika Sorvari, Liisi Soppela, Nikita Mikhailov et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Alterations in protein kinase networks in astrocytes and neurons derived from patients with familial Alzheimer’s DiseaseNicholas Henkel, Alex W. Joyce, Elizabeth Shedroff, Ali Sajid Imami, Khaled Alganem, Abdul-Rizaq Ali Hamoud, Chongchong Xu, Benjamin Siciliano, Tao Ma, Zhexing Wen et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Deficits in mitochondrial function and glucose metabolism seen in sporadic and familial Alzheimer’s disease derived Astrocytes are ameliorated by increasing hexokinase 1 expressionBell, Simon M, Wareing, Hollie, Hamshaw, Alexander, De, Suman, New, Elizabeth, Shaw, Pamela J, De Marco, Matteo, Venneri, Annalena, Blackburn, Daniel J, Ferraiuolo, Laura et al. · 2023
- TNF⍺-driven Aβ aggregation, synaptic dysfunction and hypermetabolism in human iPSC-derived cortical neuronsAlicia González Díaz, Elisa Belli, Benedetta Mannini, Gustavo Antonio Urrutia, Michele Vendruscolo · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Commentary: The Starving Brain: Overfed meets undernourished in the pathology of mild cognitive impairment (MCI) and Alzheimer's disease (AD)Kelly J. Gibas · 2018 · Journal of Immunological Sciences
- Modelling the neurobiology of Alzheimer’s disease in vitroSonia Sanz Muñoz · 2019 · Research Online (University of Wollongong)
- Targeting Alzheimer’s disease and related dementias with CRISPR and human pluripotent stem cell technologiesAndrew A. Sproul · 2021 · Elsevier eBooks
- New Prospects for Stem Cell Therapy in Alzheimer’s DiseaseKun Jiang, Yongqi Zhu, Lei Zhang · 2021 · IntechOpen eBooks
- Human induced pluripotent stem cell–derived astrocytes progenitors as discovery platformsArens Taga, Nicholas John Maragakis · 2021 · Elsevier eBooks
- References2018 · Elsevier eBooks
- Faculty Opinions recommendation of Sex-specific transcriptional and proteomic signatures in schizophrenia.Joël Bockaert · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Advantages and limitations of hiPSC-derived neurons for the study of neurodegenerationSwati Mishra, Coen Van Deursen, Aiko Robert, Rik van der Kant, Jessica E. Young · 2022 · Elsevier eBooks
- Alzheimer's Disease In Vivo Models: A Traditional ReviewSena TÜTÜNCÜ, Hülya Tezel Yalçın, Aylin BALCI ÖZYURT, Anıl Yirün, Terken Baydar, Pınar Erkekoğlu · 2023 · Journal of Literature Pharmacy Sciences
- OralsJerome J. A. Hendriks · 2023 · Glia
- β-asarone inhibits autophagic neuron death by downregulating reactive astrocytes-derived SPARC expression in LPS-induced SH-SY5Y cellsHongxia Yu, Sichen Wang, Qiaoyan Huang, Sichen Wu, Xiaoyao Tan, Xinyue Li, Yueling Xu, Shunyuan Guo, Liting Ji, Changyu Li · 2023 · Research Square
- Additional file 6 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 5 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 2 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 1 of A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patientsMahin Ghorbani, Daniel Ferreira, Silvia Maioli · 2023 · Figshare
- Additional file 4 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 3 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare