PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease
Oksanen, Minna, Petersen, Andrew J., Naumenko, Nikolay, Puttonen, Katja, Lehtonen, Šárka, Gubert Olivé, Max, Shakirzyanova, Anastasia, Leskelä, Stina, Sarajärvi, Timo, Viitanen, Matti, Rinne, Juha O., Hiltunen, Mikko, Haapasalo, Annakaisa, Giniatullin, Rashid, Tavi, Pasi, Zhang, Su-Chun, Kanninen, Katja M., Hämäläinen, Riikka H., Koistinaho, Jari·2017·Stem Cell Reports
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- Additional file 1 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 2 of A metagenomic study of gut viral markers in amyloid-positive Alzheimer’s disease patientsGhorbani, Mahin, Daniel Ferreira, Silvia Maioli · 2023 · Figshare
- Additional file 1 of Human iPSC-derived astrocytes transplanted into the mouse brain undergo morphological changes in response to amyloid-β plaquesPranav Preman, Julia TCW, Sara Calafate, An Snellinx, María Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison Goate, Bart De Strooper et al. · 2021 · Figshare
- Additional file 7 of Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer’s disease pathogenesisYuriy Pomeshchik, Erika Velásquez, Jeovanis Gil, Oxana l. Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren‐Thorsson et al. · 2023 · Figshare
- Additional file 1 of iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotypeSullivan, Michael A., Lane, Samuel D., André D. J. McKenzie, Sarah R. Ball, Sunde, Margaret, Neely, G. Gregory, Moreno, Cesar L., Alexandra Maximova, Eryn L. Werry, Michael Kassiou · 2024 · Figshare
- Additional file 1 of Comparison of two protocols for the generation of iPSC-derived human astrocytesPatrycja Mulica, Carmen Venegas, Zied Landoulsi, Katja Badanjak, Sylvie Delcambre, Maria Tziortziou, Soraya Hezzaz, Jenny Ghelfi, Semra Smajić, Jens Christian Schwamborn et al. · 2023 · Figshare
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- Glial and Neuronal Alzheimer's Disease-Related Alterations Reproduced in Human Induced Pluripotent Stem Cells With Presenilin-1 MutationDavide Comolli, Elisa Murari, Milica Cerovic, Liviu Soltuzu, Wenjie Liao, Aurora Bianchi, Serena Seminara, Ilaria Craparotta, Stefano Fumagalli, Claudia Balducci et al. · 2026 · Research Square
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- Amyloid precursor protein derivatives differentially alter the microRNA cargo of astrocyte-derived extracellular vesiclesAimee J. Chu, Anna Erlandsson, Joanna M. Williams · 2026 · Neuroscience
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- Synaptic dysfunction as a major driver in Alzheimer's disease: Beyond the amyloid paradigmNatalia Mierzwa, Michalina Wężyk · 2026 · Neuroscience & Biobehavioral Reviews
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- Written in the Stars: Astrocyte Biology From Evolution to DiseaseCarmen Falcone, Lut Arckens, Monica Baiula, Andrea Bedini, Riccardo Bocchi, Matthew James Broadhead, Marco Caprini, Fabio Cavaliere, Fabrizia Cesca, Helena Haque Chowdhury et al. · 2026 · Acta Physiologica
- Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's MiceFeifei Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang et al. · 2026 · Advanced Science
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