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PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis

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GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

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Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

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Gasdermin D plays a vital role in the generation of neutrophil extracellular traps

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Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis

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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

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Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells

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N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

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Gasdermin D Exerts Anti-inflammatory Effects by Promoting Neutrophil Death

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Cryo-EM structure of the gasdermin A3 membrane pore

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MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

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A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis

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Enterovirus 71 Inhibits Pyroptosis through Cleavage of Gasdermin D

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ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages

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Coral gasdermin triggers pyroptosis

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Teleost Gasdermin E Is Cleaved by Caspase 1, 3, and 7 and Induces Pyroptosis

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Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo

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The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E–mediated pyroptosis

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The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis

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The dominant alopecia phenotypes Bareskin, Rex-denuded, and Reduced Coat 2 are caused by mutations in gasdermin 3

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