The heterogeneity of cellular senescence: insights at the single-cell level
Cited by (304)
Items 101–200 of 304
- Profiling with senescence-associated secretory phenotype score identifies GDC-0879 as a small molecule sensitizing glioblastoma to anti-PD1Yang Liu, Yuan Feng, Lin Li Cheng, Yangxi Xu, Anhua Wu, Peng Cheng · 2025 · Cell Death and Disease
- How to measure and model cardiovascular agingLuke Spray, Gavin David Richardson, Laura K. Booth, Judith Haendeler, Joachim Altschmied, Daniel I. Bromage, Sienna B Wallis, Konstantinos Stellos, Simon Tual‐Chalot, Ioakim Spyridopoulos · 2025 · Cardiovascular Research
- Antagonistic stem cell fates under stress govern decisions between hair greying and melanomaYasuaki Mohri, Jialiang Nie, Hironobu Morinaga, Tomoki Kato, Takahiro Aoto, Takashi Yamanashi, Daisuke Nanba, Hiroyuki Matsumura, Sakura Kirino, Kouji Kobiyama et al. · 2025 · Nature Cell Biology
- Identification of senescent cell subpopulations by CITE ‐seq analysisKotb Abdelmohsen, Krystyna Mazan-Mamczarz, Rachel B. Munk, Dimitrios Tsitsipatis, Qiong Meng, Martina Sofia Rossi, Apala Pal, Chang Hoon Shin, Jennifer L. Martindale, Yulan Piao et al. · 2024 · Aging Cell
- Fisetin as a Blueprint for Senotherapeutic Agents – Elucidating Geroprotective and Senolytic Properties with Molecular ModelingSpiegel, Maciej · 2025 · Chemistry – A European Journal
- PCSK9 affects vascular senescence through the SIRT1 pathwayYuqin Wang, Shaoqing Cao, Zhangyu Wang, Chengsi Li, Jianping Ye, Yehong Liu, Tianhui Jin, Yuting Zhou, Wentao Su, Gangjun Zong · 2025 · Experimental Gerontology
- Therapy-Induced Senescence (TIS) and SASP: The p53-Mediated Interplay in Cancer Progression and TreatmentChang Hoon Lee, Tuan Minh Nguyen, Yongook Lee, Seoung Gyu Choi, Phương Ngân Nguyễn, Jung Ho Park, Mi Kyung Park · 2025 · International Journal of Molecular Sciences
- Spiny mice ( Acomys ) have evolved cellular features to support regenerative healingRobyn S. Allen, Ashley W. Seifert · 2025 · Annals of the New York Academy of Sciences
- Unraveling the metabolic heterogeneity and commonality in senescent cells using systems modelingGong‐Hua Li, Yuhong Li, Qin Yu, Qing-Qing Zhou, Runfeng Zhang, Chong-Jun Weng, Ming‐Xia Ge, Qing-Peng Kong · 2025 · Life Medicine
- Tracing Cellular Senescence in Bone: Time‐Dependent Changes in Osteocyte Cytoskeleton Mechanics and MorphologyMaryam Tilton, Junhan Liao, Chanul Kim, Hossein Shaygani, Maria D. Astudillo Potes, Domenic J. Cordova, James L. Kirkland, Kyle M. Miller · 2025 · Small
- Multiple Dimensions of using Mesenchymal Stem Cells for Treating Liver Diseases: From Bench to BesideLijun Chen, Ning Zhang, Yuqi Huang, Qi Zhang, Yangxin Fang, Jiamin Fu, Yin Yuan, Lu Chen, Xin Chen, Zhenyu Xu et al. · 2023 · Stem Cell Reviews and Reports
- Causal relationship between immune cells and telomere length: mendelian randomization analysisYujian Li, Sheng-Lin Lai, Xuan Kan · 2024 · BMC Immunology
- Endometrial Stromal Senescence Mediates the Progression of Intrauterine AdhesionsPavel I. Deryabin, Aleksandra V. Borodkina · 2025 · International Journal of Molecular Sciences
- Microglial STING is a central safeguard against neurological decline with ageKatherine B. Sulka, Kimberly A. Carroll, Machlan Sawden, Jacob W. Hopkins, Sasha A. Smolgovsky, Abraham L. Bayer, Eric R. Reed, Albert Tai, Pilar Alcaide, Philip G. Haydon et al. · 2025 · Cell Reports
- PROTAC as a novel anti-cancer strategy by targeting aging-related signalingYunhua Peng, Donghua Liu, Daoyuan Huang, Hiroyuki Inuzuka, Jing Liu · 2024 · Seminars in Cancer Biology
- Maimendong decoction modulates the PINK1/Parkin signaling pathway alleviates type 2 alveolar epithelial cells senescence and enhances mitochondrial autophagy to offer potential therapeutic effects for idiopathic pulmonary fibrosisYuhe Zhou, Wen Su, Meng-Zhen Xu, Aijun Zhang, Shaoli Li, Hong Guo, Kai Gong, Kaihui Lu, Xin Yu, Qingjun Zhu et al. · 2025 · Journal of Ethnopharmacology
- Advancing T-cell immunotherapy for cellular senescence and disease: Mechanisms, challenges, and clinical prospectsWu, Jizhun, Zhang, Lu, Zhao, Zihan, Liu, Yuping, Li, Zhengxing, Feng, Xiaohang, Zhang, Lin, Yao, Xiang, Du, Jun, Chen, Liang et al. · 2025 · Ageing Research Reviews
- EIF5A2 specifically regulates the transcription of aging-related genes in human neuroblastoma cellsYuwei Liu, Li Jen Peng, Jing Chen, Ling Chen, Ying Wu, Mengxin Cheng, Min Chen, Xujun Ye, Yalei Jin · 2023 · BMC Geriatrics
- Drugs against metabolic diseases as potential senotherapeutics for aging-related respiratory diseasesSachi Matsubayashi, Saburo Ito, Jun Araya, Kazuyoshi Kuwano · 2023 · Frontiers in Endocrinology
- Cellular senescence promotes meibomian gland dysfunction in a chronic graft-versus-host disease mouse modelShinri Sato, Yoko Ogawa, Eisuke Shimizu, Kazuki Asai, Takahiro Okazaki, Robert Rusch, Masatoshi Hirayama, Shigeto Shimmura, Kazuno Negishi, Kazuo Tsubota · 2024 · The Ocular Surface
- Chemotherapy-induced cellular senescence promotes stemness of aggressive B-cell non-Hodgkin’s lymphoma via CCR7/ARHGAP18/IKBα signaling activationJiyu Wang, Qianshan Tao, Keke Huang, Yangyang Wang, Linhui Hu, Anwen Ren, Huiping Wang, Wan Yang, Jinlan Li, Liuying Yi et al. · 2025 · Journal for ImmunoTherapy of Cancer
- Cell‐Surface LAMP1 is a Senescence Marker in Aging and Idiopathic Pulmonary FibrosisGabriel Meca-Laguna, Michael Qiu, Yafei Hou, Anna Barkovskaya, Apoorva Shankar, Bhavna Dixit, Michael J. Rae, Amutha Boominathan, Amit Sharma · 2025 · Aging Cell
- Microglial States Are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer's DiseaseBoyang Li, Shaowei Wang, Bilal E. Kerman, Cristelle Hugo, Elliot Keats Shwab, Chang Shu, Ornit Chiba‐Falek, Zoe Arvanitakis, Hussein N. Yassine · 2025 · Aging Cell
- Unraveling the meta-hallmarks between senescent and tumor cells: A new perspective for senolytic drug discoveryWei Liu, Bo Fan, Te Fang, Hongyao Li, Jin Zhang, Bo Liu, Zhiyu Liu · 2025 · Acta Pharmaceutica Sinica B
- Development of new non-viral systems for genetic modification of senescent cellsJunquera López-Seijas, Diego Miranda-Balbuena, Alba Iglesias-Fente, Marta Sacristán-Santos, Natalia Carballo-Pedrares, María C. Arufe, Ana Rey‐Rico, Juan Fafián‐Labora · 2023 · Molecular Therapy — Nucleic Acids
- CDKN2A copy number alteration in bladder cancer: Integrative analysis in patient-derived xenografts and cancer patientsMaria‐Alexandra Papadimitriou, Katerina‐Marina Pilala, Konstantina Panoutsopoulou, Panagiotis K. Levis, Georgios Kotronopoulos, Zoi Kanaki, Gedeon Loules, Μαρία Ζαμανάκου, Dimitrios Linardoutsos, Diamantis C. Sideris et al. · 2024 · Molecular Therapy Oncology
- Identification of immunosenescence of unconventional T cells in hepatocellular carcinomaRumei Li, Zhaoxi Li, Wanrong Luo, Xiaotong Zhu, Baoming Luo · 2024 · Computational Biology and Chemistry
- An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing discYiting Huang, Lauren L. Hesting, Brian R. Calvi · 2024 · PLoS Genetics
- Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancerChiara Maria Stella Herzog, Elisa Redl, J. James E. Barrett, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Julia Tevini, Roland Lang, Barbara Kofler, Martin Widschwendter · 2025 · Communications Medicine
- The cGAS-STING pathway in senescence and aging-related diseases: mechanisms and therapeutic opportunitiesShiqing Tan, Eugenie Nepovimová, Marián Valko, Klaudia Jomová, Qinghua Wu, Kamil Kuča · 2026 · Cell Communication and Signaling
- Senescent cells in systemic aging: SASP heterogeneity, immune escape, and endocrine modulationLouay Abo Qoura, Alexey Viktorovich Churov, O. N. Maltseva, К.А. Ерусланова, Guihua Zeng · 2026 · Biogerontology
- Sugt1 loss in skeletal muscle stem cells impairs muscle regeneration and causes premature muscle agingZhiming He, Xiaona Chen, Gexin Liu, Yuying Li, Feng Yang, Hao Sun, Huating Wang · 2023 · Life Medicine
- Decoding the crossroads of aging and cancer through single‐cell analysis: Implications for precision oncologyDengxiong Li, Qingxin Yu, Fanglin Shao, Jie Wang, Ruicheng Wu, Yiqing Guo, Koo Han Yoo, Zhipeng Wang, Wuran Wei, Dechao Feng · 2025 · International Journal of Cancer
- STING promotes homeostatic maintenance of tissues and confers longevity with agingJacob W. Hopkins, Katherine B. Sulka, Machlan Sawden, Kimberly A. Carroll, Ronald D. Brown, Stephen C. Bunnell, Alexander Poltorak, Albert Tai, Eric R. Reed, Shruti Sharma · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Immune therapeutic strategies for the senescent tumor microenvironmentTadahito Yasuda, Yanru Wang · 2024 · British Journal of Cancer
- The Biological Intersection Between Chemotherapy-Related Cognitive Impairment and Alzheimer DiseaseMatthew Torre, Camila A. Zanella, Mel Β. Feany · 2025 · American Journal Of Pathology
- Biological Aging and Uterine Fibrosis in Cattle: Reproductive Trade-Offs from Enhanced ProductivityYuta Matsuno, Kazuhiko Imakawa · 2025 · Cells
- Adipose immune microenvironment: catalyst of age-related adipose tissue dysfunctionYuang Song, Haonan Xing, Yucheng Luo, Bin Li, Ye Li, Ziqing Dong · 2025 · Immunity & Ageing
- Progress in anti-ageing drug research for age-related diseases: A reviewZiying Zhou, Hao-tian Duan, Si-Tu Xue, Zhuorong Li · 2025 · Ageing Research Reviews
- Cellular senescence as a therapeutic target for aging interventionYoukun Bi, Guangju Ji · 2026 · Biomedical Journal
- Implications of cellular senescence in paediatric pituitary tumoursJosé Mario González-Meljem, Juan Pedro Martínez-Barberá · 2023 · EBioMedicine
- Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during cell growth arrestFrancesco Neri, Shuyuan Zheng, Mark A. Watson, Pierre Yves Desprez, Akos A. Gerencser, Judith Campisi, Denis Wirtz, Pei-Hsun Wu, Birgit Schilling · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell typesAnerillas, Carlos, Altés, Gisela, Gresova, Katarina, Tsitsipatis, Dimitrios, Mazan-Mamczarz, Krystyna, Banarjee, Reema, Cunningham, Ana S.G., Salamini-Montemurri, Martin, Yang, Jen-Hao, Munk, Rachel et al. · 2026 · Molecular Cell
- Oversecretion of CCL3 by Irradiation-Induced Senescent Osteocytes Mediates Bone Homeostasis ImbalanceFanyu Zhao, Haiqing Han, Jing Wang, Jianping Wang, Jianglong Zhai, Guoying Zhu · 2025 · Cells
- Dual-target-activated dual-color molecular probe for imaging analysis of cellular senescenceLinlin Wang, Donghui Hong, Jili Li, Lu Wu, Yinghao Xia, Xinjia Di, Jian Wang, Yuqi Xie, Jun Da, Yanlan Liu · 2025 · Chemical Communications
- Unveiling aging heterogeneities in human dermal fibroblasts via nanosensor chemical cytometryYoungho Song, Inwoo Seo, Changyu Tian, Jiseon An, Seongcheol Park, Jiyu Hyun, Seung Pil Jung, Hyun Su Park, Hyun‐Ji Park, Suk Ho Bhang et al. · 2025 · Nature Communications
- Mechanical Stress Triggers Premature Senescence in Cardiac FibroblastsStephanie Ellyse Schneider, Adrienne K. Scott, Katie M. Gallagher, Emily Y. Miller, Soham Ghosh, Corey P. Neu · 2025 · Advanced Science
- Proximal Pulmonary Artery Stiffening as a Biomarker of Cardiopulmonary AgingRuben De Man, Zhongyu Cai, Pramath Doddaballapur, Nicole M. Guerrera, Alexandria Regan, Liqin Lin, Erica L. Schwarz, A. Justet, Nebal S. Abu Hussein, Jack Di Palo et al. · 2026 · Aging Cell
- Astrocyte States in Brain Aging and Neurodegeneration: At the Crossroads of Senescence and ReactivityJoão Bastos Lima Pacca-Corrêa, Beatriz Martins Fernandes, Michele Siqueira, Raffaela Schafbenker, Gabriela Joras Baumart, Isabella Vivarini Damico, Flávia Carvalho Alcântara Gomes, Isadora C. Pereira Matias · 2026 · Neurochemical Research
- Osteogenesis imperfecta type 10 and the cellular scaffolds underlying common immunological diseasesAlan G. Herbert · 2024 · Genes and Immunity
- Detoxification of DON-induced hepatotoxicity in mice by cold atmospheric plasmaRuonan Ma, Yongqin Fan, Xudong Yang, Chunli Liu, Junhu Wan, Xu Cui, Ruixue Wang, Junxia Feng, Zhen Jiao · 2024 · Ecotoxicology and Environmental Safety
- Cellular Senescence in Craniofacial Tissue Regeneration: Inducers, Biomarkers, and InterventionsWeibing Tang, Fangjun Huo, Jie Long, Siyuan Zhang, Weidong Tian · 2023 · Tissue Engineering Part B Reviews
- Metabolite accumulation from oral NMN supplementation drives aging-specific kidney inflammationTara A. Saleh, Jeremy D. Whitson, Phoebe Keiser, Praveena Prasad, Brenita C. Jenkins, Tori Sodeinde, Carolyn N. Mann, Peter S. Rabinovitch, Melanie R. McReynolds, Mariya T. Sweetwyne · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Senescent cell heterogeneity and responses to senolytic treatment are related to cell cycle status during senescence inductionNeri, Francesco, Zheng, Shuyuan, Watson, Mark A., Desprez, Pierre-Yves, Gerencser, Akos A., Campisi, Judith, Wirtz, Denis, Wu, Pei-Hsun, Schilling, Birgit · 2025 · Aging
- Unleashing CAR T cells to delay metabolic agingJenna M. Bartley, Ming Xu · 2024 · Nature Aging
- Unraveling the effects of FLASH and conventional irradiation on retinal pigment epithelial cells: in vitro and in vivo studiesBeatrice Di Marco, Gabriele Sansevero, Beatrice D’Orsi, Elisa De Santis, Giulia Salamone, Andrea Cavalieri, Luigi Masturzo, Mariagrazia Celentano, Fabio Di Martino, S. Capaccioli et al. · 2025 · Scientific Reports
- Microbiota-derived corisin accelerates kidney fibrosis by promoting cellular agingTaro Yasuma, Hajime Fujimoto, Corina N. D’Alessandro‐Gabazza, Masaaki Toda, Mei Uemura, Kota Nishihama, Atsuro Takeshita, Valeria Fridman D’Alessandro, Tomohito Okano, Yuko Okano et al. · 2025 · Nature Communications
- The interactome era: Integrating RNA-seq, proteomics, and network biology to decode cellular senescenceMohd Shahzaib, Domenico Aprile, Tiziana Squillaro, Nicola Alessio, Gianfranco Peluso, Giovanni Di Bernardo, Umberto Galderisi · 2025 · Ageing Research Reviews
- Imperfect repair in aging: senescent cells and the hepatic fibrotic nicheJuyeon Kim, Minseong Kim, Chuna Kim · 2026 · BMB Reports
- PQBP3 prevents senescence by suppressing PSME3-mediated proteasomal Lamin B1 degradationYuki Yoshioka, Yong Huang, Xiaocen Jin, Kien Xuan Ngo, Tomohiro Kumaki, Meihua Jin, Saori Toyoda, Sumire Takayama, Maiko Inotsume, Kyota Fujita et al. · 2024 · The EMBO Journal
- SATB1, senescence and senescence‐related diseasesWenjing Qi, Jinping Bai, Ruoxi Wang, Xianlu Zeng, Lihui Zhang · 2024 · Journal of Cellular Physiology
- Single-nucleus transcriptome reveals cell dynamic response of liver during the late chick embryonic developmentHuimei Wang, Jiongyan Liu, Pinhui Zhu, Lin Shi, Yanli Liu, Xiaojun Yang, Xin Yang · 2024 · Poultry Science
- Cellular Senescence in Acute Liver Injury: What Happens to the Young Liver?Keting He, Diwenxin Zhou, Zhangya Pu, Shangci Chen, Yangfan Shen, Shuai Zhao, Xiaohan Qian, Qingqing Hu, Xiaoxin Wu, Zhongyang Xie et al. · 2024 · Aging and Disease
- Investigating the Effects of Chelidonic Acid on Oxidative Stress-Induced Premature Cellular Senescence in Human Skin Fibroblast CellsBurcu Türkoğlu, Banu Mansuroğlu · 2024 · Life
- Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesisHunter C. Herriage, Cameron L. Hughes, Sarah K Fahey, Brian R. Calvi · 2025 · Cancer Letters
- Hypoxia and Cellular Senescence, Emerging Toxic Mechanisms of Mycotoxins and Toxins: A New Understanding of the Negative Immune RegulationsQinghua Wu, Li You, Wenda Wu, Xu Wang · 2022 · Toxins
- Vibrational phenomics decoding of the stem cell stepwise aging process at single-cell resolutionYue Wang, Yadi Wang, Xueling Li, Junhong Lü · 2024 · Chemical Communications
- Mosaic Regulation of Stress Pathways Underlies Senescent Cell HeterogeneityRoberto A. Avelar, Thomas Duffield, Cyril Lagger, Nikita Krstevska, Marian Breuer, João Pedro de Magalhães · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The emerging role of cellular senescence in amyotrophic lateral sclerosisXingli Tan, Naiyong Gao · 2025 · Frontiers in Neuroscience
- Dissecting Spatiotemporal Heterogeneity of Senescence Markers p16/p21 Across Tissues During Type 2 Diabetes ProgressionJia-Yu Yan, Zi-Mei Yi, Si-Yi Chen, Ruo-Wen Zhao, Jia-Ying Shi, Shu-Wen Ding, Jia-Yu Zhu, Jun-Hua Wu · 2025 · Cell Biochemistry and Function
- Implications of cellular senescence in Parkinson’s disease: Recent developments and future directionsJulie Kay Andersen · 2026 · Current Opinion in Neurobiology
- Current progress and future perspectives in personal identification of monozygotic twins in forensic medicineMing-hui Liu, Xia Xi, Yilong Wang, Dan‐Yang Wang, Siwen Wang, Yun-Zhou Chen, Mao-ling Sun, Jiaxin Xing, Jin‐feng Xuan, Jun Yao · 2025 · Forensic Science International Genetics
- NIPSNAP1 and NIPSNAP2 facilitate healthy aging independent of mitophagyJian Lv, Junmei Wang, Qin Chen, Qianhua Zhong, Hongchao Zhan, Qiuxiao Guo, Jiajie Li, Ningning Guo, Fang Yu, Jingjing Tong et al. · 2025 · Metabolism
- Lysosomes, caspase-mediated apoptosis, and cytoplasmic activation of P21, but not cell senescence, participate in a redundant fashion in embryonic morphogenetic cell deathCristina Duarte‐Olivenza, Goretti Moran, Juan M. Hurlé, Carlos Ignacio Lorda-Diez, Juan Antonio Montero · 2023 · Cell Death and Disease
- Molecular signatures of cellular senescence in cancer: a critical review of prognostic implications and therapeutic opportunitiesDébora Santos‐Sousa, Solon da Rosa, Eduardo Cremonese Filippi‐Chiela · 2025 · Mechanisms of Ageing and Development
- Investigation of Pancreatic-beta Cells Role in the Biological Process of AgeingRishabh Chaudhary, Janvi Khanna, Manni Rohilla, Sumeet Gupta, Seema Bansal · 2023 · Endocrine Metabolic & Immune Disorders - Drug Targets
- Uncovering the transcriptional hallmarks of endothelial cell aging via integrated single-cell analysisSarah Dobner, Lisa Kleißl, Fanni Tóth, Robert L. Paxton, Irena Yordanova, Kveta Brazdilova, Cedric Vanluyten, Aleksandra Aizenshtadt, Hanna Toth, Jake Burton et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Exercise mitigates liver senescence but does not outmatch dietary restriction in obesity-related MASLDAngeliki Katsarou, Grigorios Papadopoulos, Ioannis I. Moustakas, Αrgyro Papadopetraki, Athanasios Moustogiannis, Aigli‐Ioanna Legaki, Eirini Giannousi, George D. Agrogiannis, Pavlos Pantelis, Dimitris Veroutis et al. · 2025 · Metabolism
- Liu Jun Zi Decoction extends lifespan and healthspan through p16/p21 signaling in Caenorhabditis elegansXinyi Wang, Lu Zhang, Xiaoyan Gao, Lijun Zhang, Jing Yu, Ying Liu, Minglv Fang, Yingxuan Yan, Liang Chen, Junhui Du et al. · 2025 · Biogerontology
- Expression of Tetraspanin 4 Relative to Therapy-induced Senescence Markers in Breast Cancer in Response to Neoadjuvant ChemotherapyTareq Saleh, Sofian Al Shboul, Kholoud Friehat, Nebras Y. Melhem, Alia H. Al-Mohtaseb, Samah O. Al-Omari, Mohammad Matalka, Nisreen Abu Shahin, Shrouq Daromar, Ahmad Alhesa et al. · 2025 · Journal of Histochemistry & Cytochemistry
- Neutrophil-derived exosomal thrombospondin-1 exacerbates endothelial progenitor cell senescence and lung injury via TGF-β/SMAD signaling in COPDJunjuan Lu, Caihong Liu, Ting Yuan, Honghui Yang, Li Zhang · 2025 · Translational research
- Senolytic-loaded asymmetric wound dressing for targeted senescent cell clearance in diabetic wound healingMing Zhang, Yamei Wang, Yao Dai, Yan Hu, Wanting Fu, Yuhao Zhao, Hui Ma, Di Zhang, Ying Chen, Yixuan Zhou et al. · 2025 · Materials Today Bio
- SERS-enabled immune monitoring: Decoding the tumor microenvironment for precision Cancer immunotherapyBiqing Chen, Jiayin Gao, Haizhu Sun, Zhi Chen, Xiaohong Qiu · 2026 · International Immunopharmacology
- Senescent cell heterogeneity: origins, detection, and therapeutic implicationsRong Wu, Junyu Zhu, Hayoon Kim, Ming Xu · 2026 · Trends in Cell Biology
- Cellular senescence and nanoparticle-based therapies: Current developments and perspectivesAgata Henschke, Angelika Mielcarek, Bartosz F. Grześkowiak, Patrick M. Perrigue, Kaja Jaskot, Emerson L. Coy, Sergio Enrique Moya · 2024 · Nanotechnology Reviews
- Multiparametric identification of putative senescent cells in skeletal muscle via mass cytometryYijia Li, Nameera F. Baig, Daniel Roncancio, Kris Elbein, Dawn A. Lowe, Michael Kyba, Edgar A. Arriaga · 2024 · Cytometry Part A
- Rapid Screening of Biomarkers in KYSE-150 Cells Exposed to Polycyclic Aromatic Hydrocarbons via Inkjet Printing Single-Cell Mass SpectrometryAi Ren, Fengming Chen, Chen-jie Ren, Minli Yang, Chang Wang, Xuesong Feng, Feng Zhang · 2024 · Analytical Chemistry
- Microglia States are Susceptible to Senescence and Cholesterol Dysregulation in Alzheimer’s DiseaseBoyang Li, Shaowei Wang, Bilal E. Kerman, Cristelle Hugo, Elliot Keats Shwab, Chang Shu, Ornit Chiba‐Falek, Zoe Arvanitakis, Hussein N. Yassine · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Impact of senescence in impaired wound healingGabriel Méndez-Valdés, Catalina Rojas-Solé, José Lillo‐Moya, Ramón Rodrigo · 2024 · Advances in biogerontology
- The adverse effects of chemotherapy on bone mass are not prevented by senolyticsMd Mohsin Ali, Pilar Simmons, Aaron D. Warren, Landon B. Gatrell, Ana Resende-Coelho, Taylor McElroy, Antiño R. Allen, Maria Almeida · 2025 · Scientific Reports
- Identification of markers for neurescence through transcriptomic profiling of postmortem human brainsShiva Kazempour Dehkordi, Sogand Sajedi, Amirreza Heshmat, Miranda E. Orr, Habil Zare · 2025 · npj Aging
- Comprehensive analysis of multiple species identifies novel molecular signatures and pathways involved in agingWeijuan Cai, Kunying Chong, Bo Zhou, Yanni Zhao, Binchang Lao, Liang Yin · 2025 · Genomics
- Toward precision longevity: aging interventions in the single-cell atlas eraJason B. Chen, Miranda C. Wang, Shangyu Gong, Hongjie Li · 2025 · Frontiers in Aging
- Single-cell aging clocks: A precision tool for dissecting and targeting the aging processYuduo Hao, Sijia Xie, Yijie Wei, Xiaoshuo Sun, Yu Xiao, Xueqin Xie, Kaiyuan Han, Ting Wang, Zhepeng Wang, Luqiang Zhang et al. · 2026 · Ageing Research Reviews
- Chondrocyte Senescence in Osteoarthritis: Potential Targets and Pharmacological InterventionsDunyong Y. Tan, Jiawei Guo, Tianyu Wang, Siyao Yang, Jianquan Liu, Daping Wang, Wencui Li · 2026 · Cartilage
- Minimally Invasive Single-Cell Metabolomics Analysis to Unveil Different Trajectories of Individual Cells in FerroptosisDandan Xia, Rong Jin, Le Tong, Wei Han, Liang Qiao, Dechen Jiang · 2026 · Analytical Chemistry
- Morphofunctional Heterogeneity and Plasticity of Glioblastoma Cells Induced to Senescence by TemozolomideSolon Andrades da Rosa, Henrique M. Oliveira, Laura Boose de Mendonça, Nicole Borgmann de Oliveira, Mariane da Cunha Jaeger, Luiza Cherobini Pereira, Fernanda Dittrich Oliveira, Débora Santos‐Sousa, Fernanda Saez‐Calazans, Luana Suéling Lenz et al. · 2026 · Aging Cell
- The paracrine TAC1-TACR1 signaling promotes endothelial senescence and metastatic progression in neuroblastomaXuefei Liu, Yuting Wang, Yixin Cheng, Xiuli Yuan, Yi Li, Jingru Lian, Yifei Duan, Shuqian Zheng, Chun Wu, Garry Huang et al. · 2026 · Cancer Letters
- Trophoblast aging driven by IL33 deficiency elevates recurrent pregnancy loss risk through SNAP29 lactylation-mediated autophagy impairmentJia-Jing Lu, Yan‐Ran Sheng, Wenting Hu, Yukai Liu, Feng Xie, Ming‐Qing Li, Xiao‐Yong Zhu · 2026 · Autophagy
- From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitisJames Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem E. Sahingur, Yvonne Lorraine Kapila · 2026 · Periodontology 2000