The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
19F MRI for quantitative in vivo cell tracking
Open accessAbstract
Cellular therapy, including stem cell transplants and dendritic cell vaccines, is typically monitored for dosage optimization, accurate delivery and localization using non-invasive imaging, of which magnetic resonance imaging (MRI) is a key modality. 19F MRI retains the advantages of MRI as an imaging modality, while allowing direct detection of labelled cells for unambiguous identification and quantification, unlike typical metal-based contrast agents. Recent developments in 19F MRI-based in vivo cell quantification, the existing clinical use of 19F compounds and current explosive interest in cellular therapeutics have brought 19F imaging technology closer to clinical application. We review the application of 19F MRI to cell tracking, discussing intracellular 19F labels, cell labelling and in vivo quantification, as well as the potential clinical use of 19F MRI.
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de Vries, I. J. M., Lesterhuis, W. J., Barentsz, J. O., Verdijk, P., van Krieken, J. H., Boerman, O. C., Oyen, W. J. G., Bonenkamp, J. J., Boezeman, J. B., Adema, G. J., et al. (2005) · Nature Biotechnology · doi:10.1038/nbt1154 · Cited by 821
Self-citationIn vivo MRI cell tracking: clinical studies
Bulte, J. W. M. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.09.3107 · Cited by 430
Cited by
19F Magnetic Resonance Imaging (MRI): From Design of Materials to Clinical Applications
Tirotta, I., Dichiarante, V., Pigliacelli, C., Cavallo, G., Terraneo, G., Bombelli, F. B., Metrangolo, P., & Resnati, G. (2015) · Chemical Reviews · doi:10.1021/cr500286d · Cited by 521
Advanced functional materials based on polyhedral oligomeric silsesquioxane (POSS)
Tanaka, K., & Chujo, Y. (2012) · J. Mater. Chem. · doi:10.1039/c1jm14231c · Cited by 489
In vivo MRI cell tracking: clinical studies
Bulte, J. W. M. (2009) · American Journal of Roentgenology · doi:10.2214/ajr.09.3107 · Cited by 430
Customizing poly(lactic-co-glycolic acid) particles for biomedical applications
Swider, E., Koshkina, O., Tel, J., Cruz, L. J., de Vries, I. J. M., & Srinivas, M. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.04.006 · Cited by 328
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Metadata
- Authors
- Srinivas, M., Heerschap, A., Ahrens, E. T., Figdor, C. G., & Vries, I. J. M. D.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2010-07
- Volume
- 28
- Issue
- 7
- Pages
- 363-370
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2006150035
- Cited by
- 285
- References
- 2
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- green
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- Srinivas, M., Heerschap, A., Ahrens, E. T., Figdor, C. G., & Vries, I. J. M. D. (2010). 19F MRI for quantitative in vivo cell tracking. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2010.04.002
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