The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Skin regeneration scaffolds: a multimodal bottom-up approach
Open accessAbstract
Skin wounds are a major social and financial burden. However, current treatments are suboptimal. The gradual comprehension of the finely orchestrated nature of intercellular communication has stimulated scientists to investigate growth factor (GF) or stem cell (SC) incorporation into suitable scaffolds for local delivery into wound beds in an attempt to accelerate healing. This review provides a critical evaluation of the status quo of current research into GF and SC therapy and subsequent future prospects, including benefits and possible long-term dangers associated with their use. Additionally, we stress the importance of a bottom-up approach in scaffold fabrication to enable controlled factor incorporation as well as production of complex scaffold micro- and nanostructures resembling that of natural extracellular matrix.
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Cites
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
The FGF family: biology, pathophysiology and therapy
Beenken, A., & Mohammadi, M. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2792 · Cited by 1,945
Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair
Hocking, A. M., & Gibran, N. S. (2010) · Experimental Cell Research · doi:10.1016/j.yexcr.2010.05.009 · Cited by 408
Cited by
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Progress in Hydrogels for Skin Wound Repair
Qi, L., Zhang, C., Wang, B., Yin, J., & Yan, S. (2022) · Macromolecular Bioscience · doi:10.1002/mabi.202100475 · Cited by 267
Yildirimer, L., & Seifalian, A. M. (2014) · Biotechnology Advances · doi:10.1016/j.biotechadv.2014.04.014 · Cited by 98
Self-citationFrom Grafts to Human Bioengineered Vascularized Skin Substitutes
Oualla-Bachiri, W., Fernández-González, A., Quiñones-Vico, M. I., & Arias-Santiago, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218197 · Cited by 69
Barsch, F., Mamilos, A., Schmitt, V. H., Babel, M., Winter, L., Wagner, W., Winther, H., Ottomann, C., Niedermair, T., Schreml, S., et al. (2022) · Cells · doi:10.3390/cells11182834 · Cited by 6
Metadata
- Authors
- Yildirimer, L., Thanh, N. T. K., & Seifalian, A. M.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2012-12
- Volume
- 30
- Issue
- 12
- Pages
- 638-648
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2117808317
- Cited by
- 286
- References
- 3
- FWCI
- 1.84
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Yildirimer, L., Thanh, N. T. K., & Seifalian, A. M. (2012). Skin regeneration scaffolds: a multimodal bottom-up approach. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2012.08.004
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