The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Deep Eutectic Solvents as Efficient Solvents in Biocatalysis
Abstract
'Ideal' solvents in biocatalysis have to fulfill a large number of requirements, such as high substrate solubility, high enzyme activity and stability, and positive effects on reaction equilibrium. In the past decades, many enzymatic synthesis routes in water-based and nonaqueous (organic solvents, ionic or supercritical fluids) reaction media have been developed. However, no solvent meets every demand for different reaction types at the same time, and there is still a need for novel solvents suited for different reaction types and applications. Deep eutectic solvents (DESs) have recently been evaluated as solvents in different biocatalytic reactions. They can improve substrate supply, conversion, and stability. The best results were obtained when the DES is formed by the substrates of an enzymatic reaction.
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Cited by
Deep eutectic solvents: A review of fundamentals and applications
Hansen, B. B., Spittle, S., Chen, B., Poe, D., Zhang, Y., Klein, J. M., Horton, A., Adhikari, L., Zelovich, T., Doherty, B. W., et al. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00385 · Cited by 3,422
Bolivar, J. M., Woodley, J. M., & Fernandez-Lafuente, R. (2022) · Chemical Society Reviews · doi:10.1039/d2cs00083k · Cited by 585
Enzyme entrapment, biocatalyst immobilization without covalent attachment
Imam, H. T., Marr, P. C., & Marr, A. C. (2021) · Green Chemistry · doi:10.1039/d1gc01852c · Cited by 328
Natural Deep Eutectic Solvents (NaDES): Green Solvents for Pharmaceutical Applications and Beyond
Chevé-Kools, E., Choi, Y. H., Roullier, C., Ruprich-Robert, G., Grougnet, R., Chapeland-Leclerc, F., & Hollmann, F. (2025) · Green Chemistry · doi:10.1039/d4gc06386d · Cited by 156
Jia, L., Huang, X., Zhao, W., Wang, H., & Jing, X. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.126424 · Cited by 96
Metadata
- Authors
- Pätzold, M., Siebenhaller, S., Kara, S., Liese, A., Syldatk, C., & Holtmann, D.
- Venue
- Trends in Biotechnology
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 37
- Issue
- 9
- Pages
- 943-959
- ISSN
- 0167-7799 (ISSN-L)
- OpenAlex
- W2935975288
- Cited by
- 422
- References
- 72
- FWCI
- 1.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Pätzold, M., Siebenhaller, S., Kara, S., Liese, A., Syldatk, C., & Holtmann, D. (2019). Deep Eutectic Solvents as Efficient Solvents in Biocatalysis. Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2019.03.007
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