Bioactive compounds of rice (Oryza sativa L.): Review on paradigm and its potential benefit in human health
Abstract
Knowledge of rice's nutritional value and health benefits is essential to increase rice consumption in people's daily diet. Rice is known as a queen of cereal crops that have a high nutritional value such as carbohydrate, fat, fiber, protein, vitamins as well as food energy, minerals profile and fatty acids.The present review paper mainly focuses on the chemistry of rice bioactive compounds, methods of extraction, identification, and characterization as well as biological activities and health benefits.The nutritional components are found in various types of rice which grown and utilized by farmers and consumers respectively with more than 60% population worldwide. In addition to nutritional components, there are many phytochemicals present in rice have been identified as bioactive compounds which have their many high biological activities, in which antioxidant, anticancer, antidiabetic and antiinflammation activities are major one, as other cereals have and also exhibit their potential beneficial health effects in human as they all consume rice in their daily routine diet.
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The rice grain consists of several layers, including hull, bran, germ, and endosperm, each with distinct phytochemical properties relevant to pharmacognosy.
“The rice grain itself consists of several layers, including the hull (husks), bran, germ, and endosperm, each with distinct phytochemical properties relevant to pharmacognosy (Verma and Srivastav, 2020;Cheung, 2005;FAO, 2021).”
From Pharmacognostic and dermatological insights into Oryza sativa: A comprehensive review of its skin benefits and bioactive compounds (2025) · cites this paper as Verma and Srivastav, 2020
While in vitro and animal studies have shown promising results, human clinical trials are still relatively scarce.
“Furthermore, while in vitro and animal studies have shown promising results, human clinical trials are still relatively scarce, highlighting the necessity for more rigorous scientific evaluation (Asadollahi et al., 2024;Verma and Srivastav, 2020).”
From Pharmacognostic and dermatological insights into Oryza sativa: A comprehensive review of its skin benefits and bioactive compounds (2025) · cites this paper as Verma and Srivastav, 2020
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Banwo, K., Olojede, A. O., Adesulu-Dahunsi, A. T., Verma, D. K., Thakur, M., Tripathy, S., Singh, S., Patel, A. R., Gupta, A. K., Aguilar, C. N., et al. (2021) · Food Bioscience · doi:10.1016/j.fbio.2021.101320 · Cited by 313 · see citing works
Self-citationSingh, S., Verma, D. K., Thakur, M., Tripathy, S., Patel, A. R., Shah, N., Utama, G. L., Srivastav, P. P., Benavente-Valdés, J. R., Chávez-González, M. L., et al. (2021) · Food Research International · doi:10.1016/j.foodres.2021.110746 · Cited by 98 · see citing works
Self-citationCompatibility of Whole Wheat-Based Composite Flour in the Development of Functional Foods
Weerarathna, A., & Wansapala, M. A. J. (2024) · Food Technology and Biotechnology · doi:10.17113/ftb.62.04.24.8588 · Cited by 11 · see citing works
Mubassir, Naseem, A., Km., P., & Km., N. B. (2025) · Journal of Pharmacognosy and Phytotherapy · doi:10.5897/jpp2025.0647
- Authors
- Verma, D. K., & Srivastav, P. P.
- Affiliations
- Indian Institute of Technology Kharagpur (IN)
- Corresponding author
- Verma, Deepak Kumar
- Venue
- Trends in Food Science & Technology
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 97
- Pages
- 355-365
- ISSN
- 0924-2244 (ISSN-L)
- OpenAlex
- W3000658962
- Cited by
- 223
- References
- 0
- Citations by year
- 2026: 22 · 2025: 38 · 2024: 50 · 2023: 45 · 2022: 36 · 2021: 26 · 2020: 6
- FWCI
- 17.13
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Food Science & Technology (publishedVersion)
- Funders
- Govt. of India for an individual research fellowship (IF120725)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › GABA and Rice Research
- Keywords
- rice, bioactive compounds, phytochemicals, nutritional composition, antioxidant activity, anticancer activity, antidiabetic activity, anti-inflammatory activity, extraction methods, health benefits, cereals
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