The DOI matches its Crossref record; 100 of the 100 references it cites were found in a registry or an index.
The aneuploidy paradox: costs and benefits of an incorrect karyotype
Open accessAbstract
Aneuploidy has a paradoxical effect on cell proliferation. In all normal cells analyzed to date, aneuploidy has been found to decrease the rate of cell proliferation. Yet, aneuploidy is also a hallmark of cancer, a disease of enhanced proliferative capacity, and aneuploid cells are frequently recovered following the experimental evolution of microorganisms. Thus, in certain contexts, aneuploidy may also have growth-advantageous properties. New models of aneuploidy and chromosomal instability have shed light on the diverse effects that karyotypic imbalances have on cellular phenotypes, and suggest novel ways of understanding aneuploidy’s role in development and disease.
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2 retracted
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RetractedTRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes
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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
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MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
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The spindle-assembly checkpoint in space and time
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Cited by
Chromosomal duplication is a transient evolutionary solution to stress
Yona, A. H., Manor, Y. S., Herbst, R. H., Romano, G. H., Mitchell, A., Kupiec, M., Pilpel, Y., & Dahan, O. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211150109 · Cited by 376
Holland, A. J., & Cleveland, D. W. (2012) · EMBO reports · doi:10.1038/embor.2012.55 · Cited by 288
De Storme, N., & Mason, A. (2014) · Current Plant Biology · doi:10.1016/j.cpb.2014.09.002 · Cited by 288
Single-chromosome Gains Commonly Function as Tumor Suppressors
Sheltzer, J. M., Ko, J. H., Replogle, J. M., Habibe Burgos, N. C., Chung, E. S., Meehl, C. M., Sayles, N. M., Passerini, V., Storchova, Z., & Amon, A. (2017) · Cancer Cell · doi:10.1016/j.ccell.2016.12.004 · Cited by 201
Self-citationBennett, R. J., Forche, A., & Berman, J. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a019604 · Cited by 118
Metadata
- Authors
- Sheltzer, J. M., & Amon, A.
- Venue
- Trends in Genetics
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 27
- Issue
- 11
- Pages
- 446-453
- ISSN
- 0168-9525 (ISSN-L)
- OpenAlex
- W1993344012
- Cited by
- 277
- References
- 100
- FWCI
- 0.86
- Type
- journal article
- Language
- en
- Open access
- green
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- Sheltzer, J. M., & Amon, A. (2011). The aneuploidy paradox: costs and benefits of an incorrect karyotype. Trends in Genetics. https://doi.org/10.1016/j.tig.2011.07.003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
