Cited by 159Neuroendocrine regulation and behaviorStress Responses and CortisolMaternal Mental Health During Pregnancy and Postpartum

The DOI matches its Crossref record; 119 of the 119 references it cites were found in a registry or an index.

Parenting and plasticity

Open access

Leuner, Benedetta, Glasper, Erica R., Gould, Elizabeth·2010·Trends in Neurosciences

DOI 10.1016/j.tins.2010.07.003PMC PMC3076301

Open this paper in CoChat — free account

Abstract

As any new parent knows, having a baby provides opportunities for enrichment, learning and stress - experiences known to change the adult brain. Yet surprisingly little is known about the effects of maternal experience, and even less about the effects of paternal experience, on neural circuitry not directly involved in parenting. Here we discuss how caregiving and the accompanying experiential and hormonal changes influence the hippocampus and prefrontal cortex, brain regions involved in cognition and mood regulation. A better understanding of how parenting impacts the brain is likely to help in devising strategies for treating parental depression, a condition that can have serious cognitive and mental health consequences for children.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.tins.2010.07.003

Cites

119 of 119 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Neurogenesis in the adult human hippocampus
Eriksson, P. S., Perfilieva, E., Björk-Eriksson, T., Alborn, A.-M., Nordborg, C., Peterson, D. A., & Gage, F. H. (1998) · Nature Medicine · doi:10.1038/3305 · Cited by 6,369
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,586
The Infant's Response to Entrapment between Contradictory Messages in Face-to-Face Interaction
Tronick, E., Als, H., Adamson, L., Wise, S., & Brazelton, T. B. (1978) · Journal of the American Academy of Child Psychiatry · doi:10.1016/s0002-7138(09)62273-1 · Cited by 1,880 · cited 1×
“For example, babies become noticeably distressed when an adult (mother, father or unrelated caregiver) maintains a non-interactive still face [106,107].”
Neurocircuitry of Mood Disorders
Price, J. L., & Drevets, W. C. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.104 · Cited by 1,606
Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus
Cameron, H. A., & Mckay, R. D. G. (2001) · Journal of Comparative Neurology · doi:10.1002/cne.1040 · Cited by 1,585
Gonadal steroids regulate dendritic spine density in hippocampal pyramidal cells in adulthood
Gould, E., Woolley, C., Frankfurt, M., & McEwen, B. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-04-01286.1990 · Cited by 1,406
Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2004) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2004.09.006 · Cited by 1,329
Maternal care, hippocampal synaptogenesis and cognitive development in rats
Liu, D., Diorio, J., Day, J. C., Francis, D. D., & Meaney, M. J. (2000) · Nature Neuroscience · doi:10.1038/77702 · Cited by 1,195
Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
Woolley, C. S., Gould, E., & McEwen, B. S. (1990) · Brain Research · doi:10.1016/0006-8993(90)90778-a · Cited by 1,020
Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
Cameron, H. A., & Gould, E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90224-0 · Cited by 999

Flagged first, then by citations

Show all 117 references

Research works printed but not linked: 1

Kozorovitskiy, Y. et al. (2007) Fatherhood influences neurogenesis in the hippocampus of California mice. In Proceedings of the 2007 Neuroscience Meeting, Abstract 626.21, Society for Neuroscience.

Sorted by citations

Items 101–158 of 158

Recent Neuroscience Advances in Human Parenting
Martínez‐Garcia, M., Cárdenas, S. I., Pawluski, J. L., Carmona, S., & Saxbe, D. (2022) · Advances in neurobiology · doi:10.1007/978-3-030-97762-7_8 · Cited by 9
The parental umwelt: Effects of parenthood on sensory processing in rodents
Wilson, K. M., Arquilla, A. M., & Wendy Saltzman, A. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13237 · Cited by 11
Association between parental behaviors and structural plasticity in the brain of male rodents
Inada, K., & Miyamichi, K. (2023) · Neuroscience Research · doi:10.1016/j.neures.2023.06.007 · Cited by 9
Maternal experience and territorial behavior in ground squirrels
Nunes, S. (2014) · Journal of Mammalogy · doi:10.1644/13-mamm-a-284 · Cited by 9
Impact of parturition on maternal cardiovascular and neuronal integrity in a high risk cohort – a prospective cohort study
Evers, K. S., Huhn, E. A., Fouzas, S., Barro, C., Kühle, J., Fisch, U., Bernasconi, L., Lapaire, O., & Wellmann, S. M. (2019) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-019-2570-6 · Cited by 8
Physiologic Correlates of Interactions between Adult Male and Immature Long-tailed Macaques (Macaca fascicularis).
Bardi, M., Prugh, A. M., Eubanks, B., Trexler, K. R., Bowden, R., Evans, S., Lambert, K. G., & Huffman, M. A. (2017) · Europe PMC (PubMed Central) · Cited by 8
Narrative coherence across the transition to parenthood: Primiparous parents' representations of their child in relation to parental sensitivity
Branger, M. C. E., Emmen, R. A. G., Woudstra, M. J., Alink, L. R. A., & Mesman, J. (2022) · Acta Psychologica · doi:10.1016/j.actpsy.2022.103581 · Cited by 7
The Impact of Ethologically Relevant Stressors on Adult Mammalian Neurogenesis
Jorgensen, C., Taylor, J. A., & Barton, T. (2019) · Brain Sciences · doi:10.3390/brainsci9070158 · Cited by 7
Neural responses to pup calls and pup odors in California mouse fathers and virgin males
Wilson, K. M., Arquilla, A. M., Rosales-Torres, K. M., Hussein, M., Chan, M. G., Razak, K. A., & Wendy Saltzman, A. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114024 · Cited by 7
Olfactory attractants and parity affect prenatal androgens and territoriality of coyote breeding pairs
Schell, C. J., Young, J. K., Lonsdorf, E. V., Mateo, J. M., & Santymire, R. M. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.06.038 · Cited by 8
The central role of the individual in the history of brains
Ghazanfar, A. A., & Gómez-Marín, À. (2024) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105744 · Cited by 6
Fatherhood diminishes the hippocampal damaging action of excitotoxic lesioning in mice
Anagnostou, I., & Morales, T. (2019) · Journal of Neuroendocrinology · doi:10.1111/jne.12783 · Cited by 6
Fatherhood increases attraction to sensory stimuli from unrelated pups in male California mice, Peromyscus californicus
Arquilla, A. M., Wilson, K. M., Razak, K. A., & Wendy Saltzman, A. (2023) · Animal Behaviour · doi:10.1016/j.anbehav.2023.02.001 · Cited by 6
An IL-6 receptor antagonist attenuates postpartum anhedonia, but has no effect on anhedonia precipitated by subchronic stress in female rats
Gomez, J., Haas, N. A., & Schwarz, J. M. (2019) · Psychopharmacology · doi:10.1007/s00213-019-05194-3 · Cited by 6
Experience of Adversity during a First Lactation Modifies Prefrontal Cortex Morphology in Primiparous Female Rats: Lack of Long Term Effects on a Subsequent Lactation
Opala, E. A., Verlezza, S., Long, H., Rusu, D., Woodside, B. C., & Walker, C. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.08.022 · Cited by 6
Experience-Regulated Neuronal Signaling in Maternal Behavior
Fuentes, I., Morishita, Y., González-Salinas, S., Champagne, F. A., Uchida, S., & Shumyatsky, G. P. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.844295 · Cited by 8
Dopamine drives persistent remodelling of the maternal brain
O’Chan, J. C., Salvo, G. D., Cunningham, A. M., Dutta, S., Brindley, E., Weekley, B. H., Chen, W., Iyer, R. R., Wan, E., Zhang, C., et al. (2026) · Nature · doi:10.1038/s41586-026-10509-4 · Cited by 7
A pilot randomised controlled trial on the effectiveness of infant massage on the acceptance, commitment and awareness of influence in parents of babies with Down syndrome
Pinto, E. P., Romero‐Galisteo, R. P., Jiménez‐Rejano, J., Escobio-Prieto, I., Peña-Salinas, M., Luque-Moreno, C., & Palomo‐Carrión, R. (2022) · Journal of Intellectual Disability Research · doi:10.1111/jir.12983 · Cited by 5
Functional near‐infrared spectroscopy is a useful tool for multi‐perspective psychobiological study of neurophysiological correlates of parenting behaviour
Russo, C., & Senese, V. P. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15890 · Cited by 6
Stress-Sensitive Parental Brain Systems Regulate Emotion Response and Motivate Sensitive Child Care
Swain, J. E. (2017) · Springer eBooks · doi:10.1007/978-3-319-65077-7_14 · Cited by 5
Editorial: Experience-Dependent Neuroplasticity Across the Lifespan: From Risk to Resilience
Glasper, E. R., & Neigh, G. N. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00335 · Cited by 5
Long-term cellular and molecular signatures of pregnancy in the adult and ageing brainPreprint
Duarte‐Guterman, P., Richard, J. E., Lieblich, S. E., Eid, R., Lamers, Y., & Galea, L. A. M. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.24.529879 · Cited by 5
Postpartum adversity in rats creates a hypervigilant maternal state through selective salience-circuit recruitment
Song, M., McKie, I., Su, A., Win, V., Nikitah, I., Yamamoto, M., Bendale, M. P., Maignan, F.-W., Fogus, K., & Opendak, M. M. (2026) · Neurobiology of Stress · doi:10.1016/j.ynstr.2026.100795 · Cited by 4
“养育脑”网络及其影响因素
Zhang, H., Zhang, M., Ding, R., Li, S., & Luo, W. (2019) · Advances in Psychological Science · doi:10.3724/sp.j.1042.2019.01072 · Cited by 4
The “Plastic” Mother
Palanza, P. (2017) · Endocrinology · doi:10.1210/en.2017-00071 · Cited by 4
Effects of sensory overstimulation in postpartum rats
Porras, A., Rodney‐Hernández, P., Nguyen, C. P., & Rincón‐Cortés, M. (2024) · Physiology & Behavior · doi:10.1016/j.physbeh.2024.114547 · Cited by 4
The emerging health paradigm in the 21st century: the formative first 1000 days of life
Angulo, J. M. D. (2016) · Christian Journal for Global Health · doi:10.15566/cjgh.v3i2.38 · Cited by 4
Preliminary report: Sleep duration during late pregnancy predicts postpartum emotional responses among parents at risk for postpartum depression
Mason, G. M., Cohen, Z. L., Obeysekare, J., Saletin, J., & Sharkey, K. M. (2024) · SLEEP Advances · doi:10.1093/sleepadvances/zpae068 · Cited by 3
Effects of reproductive experience on cost-benefit decision making in female rats
Faraji, M., Viera-Resto, O. A., Setlow, B., & Bizon, J. L. (2024) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2024.1304408 · Cited by 4
Neurobiological mechanisms underlying oxytocin-mediated parental behavior in rodents
Inada, K. (2024) · Neuroscience Research · doi:10.1016/j.neures.2024.04.001 · Cited by 3
Cognition and Neuroplasticity During Pregnancy and Postpartum
Blankers, S. A., Go, K. A., Surtees, D. C., Splinter, T. F. L., & Galea, L. A. M. (2024) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-51138-7_9 · Cited by 3
Single-Cell Peptide Profiling to Distinguish Stickleback Ecotypes with Divergent Breeding Behavior
Bell, S. E., Xie, Y. R., Maciejewski, M. F., Rubakhin, S. S., Romanova, E. V., Bell, A. M., & Sweedler, J. V. (2025) · Journal of Proteome Research · doi:10.1021/acs.jproteome.4c00832 · Cited by 3
Association Between Nonparenting Adult’s Attachment Patterns and Brain Structure and Function
Letourneau, N. L., Hart, J. M., & MacMaster, F. P. (2017) · SAGE Open Nursing · doi:10.1177/2377960816685572 · Cited by 3
Polygenic scores for social science: Clarification, consensus, and controversy
BURT, C. H. (2023) · Behavioral and Brain Sciences · doi:10.1017/s0140525x23000845 · Cited by 2
Adult Neurogenesis and Social Behavior: A Reciprocal Relationship
Jorgensen, C., & Wang, Z. (2024) · Masterclass in neuroendocrinology · doi:10.1007/978-3-031-51112-7_6 · Cited by 2
Longitudinal neuroanatomical increases from early to one-year postpartum
Dufford, A. J., Patterson, G., & Kim, P. (2024) · Brain Structure and Function · doi:10.1007/s00429-024-02852-x · Cited by 2
Reproductive experience drives changes in behaviour and physiology in male California mice, Peromyscus californicus
Colt, M. E., Agarwal, P., Kolb, D., Glasper, E. R., & Fisher, H. S. (2025) · Animal Behaviour · doi:10.1016/j.anbehav.2025.123216 · Cited by 2
Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartumPreprint
Chan, J. C., Salvo, G. D., Cunningham, A. M., Dutta, S., Brindley, E., Weekley, B. H., Wan, E., Zhang, C., Mechawar, N., Turecki, G., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.20.639313 · Cited by 2
Male caregiving experience alters hippocampal neuroplasticity and transcription independent of reproduction in a biparental species
Colt, M. E., Agarwal, P., Glasper, E. R., & Fisher, H. S. (2025) · Communications Biology · doi:10.1038/s42003-025-08530-w · Cited by 1
Sex‐Specific Effects of Experience With Pups on Perineuronal Net Expression in the Biparental California Mouse ( Peromyscus californicus )
Acosta, M. C., Warren, I. D., Wendy Saltzman, A., & Razak, K. A. (2025) · The Journal of Comparative Neurology · doi:10.1002/cne.70104 · Cited by 1
Sex differences and parental experience contribute to hippocampal remodelling across the lifespan
Duarte‐Guterman, P., & Zugno-Gadea, N. (2023) · Current Opinion in Physiology · doi:10.1016/j.cophys.2023.100703 · Cited by 2
Disfunção neuroquímica na depressão periparto
Rosa, C. E. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.17.2017.tde-27072016-151947 · Cited by 1
Travail reproductif et parentalité
Gabaret, J. (2021) · Le philosophoire · doi:10.3917/phoir.056.0083
Social instability, hippocampal plasticity and resilience
Opendak, M. M. (2015)
Biological and Social Causation of Serious Mental Illness
McKenzie, K. J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-420190-3.00026-0
Associação entre experiências precoces adversas e comportamentos relacionados ao suicídio na vida adulta
Coêlho, B. M. (2018) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2018.tde-31012018-085700
The Influence of Maternal Meta-Emotion Philosophy on Mother–Child Reciprocal Affect Reactions During Task Interactions
Nahm, E. Y., & Park, S. (2018) · Korean Journal of Child Studies · doi:10.5723/kjcs.2018.39.4.81
Relações entre ocitocina, apego e sono em pessoas com Transtorno de Ansiedade Generalizada
Vale, E. A. N. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.47.2019.tde-16082019-110304
Mating-induced prolactin surge is not required for subsequent neurogenesis in male mice
Smiley, K. O., Phillipps, H. R., Fang, C., Brown, R. S. E., & Grattan, D. R. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1227726
Effects of Reproductive Experience on Cost-Benefit Decision Making in Females and MalesPreprint
Faraji, M., Viera-Resto, O. A., Setlow, B., & Bizon, J. L. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.03.565418
Reproductive experience drives changes in behavior and physiology in male California mice ( Peromyscus californicus )Preprint
Colt, M. E., Agarwal, P., Kolb, D., Glasper, E. R., & Fisher, H. S. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.08.617085
What Happens in the Brain when Music Evokes Emotions?
Koelsch, S. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009366755.012
Emotions in the Brain
Koelsch, S. (2025) · Cambridge University Press eBooks · doi:10.1017/9781009366755.013
Neurosequential Learning Strategies and the Impact of Societal Racism
Gardner, A. (2022) · doi:10.1108/978-1-64802-784-020251007
Different early-life adversity paradigms have disparate effects on maternal care, neuronal activation, and social behavior in developing mice
Bapat, V. A., Waters, R. C., Gordon, J. K., & Gould, E. (2026) · Neurobiology of Stress · doi:10.1016/j.ynstr.2026.100788
Elevated ambient temperature reduces parental contact and alters caregiving posture in biparental prairie voles
Laser, R. S., & Ophir, A. G. (2026) · Animal Behaviour · doi:10.1016/j.anbehav.2026.123594
Vasopressin signaling and vasopressin-to-oxytocin receptor crosstalk in the regulation of parental caregiving behavior
Inada, K. (2026) · Neuroscience Research · doi:10.1016/j.neures.2026.105109
Associations Between Parity and Parasympathetic Regulation in Response to Infant Crying
Gemignani, M., Sinisalo, H., & Peltola, M. J. (2026) · Developmental Psychobiology · doi:10.1002/dev.70214

Authors: Leuner, B., Glasper, E. R., & Gould, E.
Affiliations: Princeton University (US)
Corresponding author: Gould, Elizabeth
ORCID: Leuner, Benedetta
Glasper, Erica R.
Gould, Elizabeth
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2010-10
Volume: 33
Issue: 10
Pages: 465-473
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2010.07.003
PMC: PMC3076301
OpenAlex: W2102804349
Cited by: 159
References: 117
Citations by year: 2026: 6 · 2025: 7 · 2024: 9 · 2023: 10 · 2022: 11 · 2021: 9 · 2020: 7 · 2019: 16 · 2018: 9 · 2017: 12 · 2016: 19 · 2015: 15 · 2014: 14 · 2013: 5 · 2012: 6
FWCI: 0.59
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (5r01mh054970-03)
National Institute on Aging (F32AG033461)
National Institute of Mental Health (R01MH059740, MH084148, MH-54970, R00MH084148, K99MH084148)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords: parenting, neuroplasticity, maternal experience, fathers' experiences, caregiving, hippocampus, prefrontal cortex, parental depression, mood regulation, cognitive development, neuroendocrine changes
MeSH terms: Adult, Affect, Brain, Cognition, Depression, Hippocampus, Hormones, Humans, Parents, Stress, Psychological, Parenting, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Parenting and plasticity

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks