Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates

Dalley, Jeffrey W.; Cardinal, Rudolf N.; Robbins, Trevor W.

doi:10.1016/j.neubiorev.2004.09.006

Cited by 1,329Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates

Dalley, Jeffrey W., Cardinal, Rudolf N., Robbins, Trevor W.·2004·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2004.09.006

Open this paper in CoChat — free account

Abstract

The prefrontal cortex has been implicated in a variety of cognitive and executive processes, including working memory, decision-making, inhibitory response control, attentional set-shifting and the temporal integration of voluntary behaviour. This article reviews current progress in our understanding of the rodent prefrontal cortex, especially evidence for functional divergence of the anatomically distinct sub-regions of the rat prefrontal cortex. Recent findings suggest clear distinctions between the dorsal (precentral and anterior cingulate) and ventral (prelimbic, infralimbic and medial orbital) sub-divisions of the medial prefrontal cortex, and between the orbitofrontal cortex (ventral orbital, ventrolateral orbital, dorsal and ventral agranular cortices) and the adjacent medial wall of the prefrontal cortex. The dorso-medial prefrontal cortex is implicated in memory for motor responses, including response selection, and the temporal processing of information. Ventral regions of the medial prefrontal cortex are implicated in interrelated 'supervisory' attentional functions, including attention to stimulus features and task contingencies (or action-outcome rules), attentional set-shifting, and behavioural flexibility. The orbitofrontal cortex is implicated in lower-order discriminations, including reversal of stimulus-reward associations (reversal learning), and choice involving delayed reinforcement. It is anticipated that a greater understanding of the prefrontal cortex will come from using tasks that load specific cognitive and executive processes, in parallel with discovering new ways of manipulating the different sub-regions and neuromodulatory systems of the prefrontal cortex.

Integrity signals

Registry

Crossref · 10.1016/j.neubiorev.2004.09.006

Cites

146 of 146 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The rodent PFC participates in functions such as attention, decision making and memory.
“Like in primates, the PFC in rodents is considered to participate in functions such as attention, decision making and memory (Chudasama, 2011; Dalley et al., 2004; Preston and Eichenbaum, 2013).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Dalley et al., 2004
The rodent mPFC is anatomically divided into ACC, PLC and ILC, located along the dorsal-ventral axis, and these subareas are reciprocally interconnected.
“The rodent mPFC can be anatomically divided into three subareas, namely the anterior cingulate cortex (ACC), prelimbic cortex (PLC) and infralimbic cortex (ILC), which are located along the dorsal – ventral axis (Dalley et al., 2004; Gabbott et al., 2005), and are reciprocally interconnected (Heidbreder and Groenewegen, 2003).”
From The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties (2020) · cites this paper as Dalley et al., 2004

The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works
The Principles of Psychology
James, W. (1891) · Henry Holt and Company eBooks · doi:10.1037/11059-000 · Cited by 25,799 · see citing works
Specific impairments of planning
Shallice, T. (1982) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1982.0082 · Cited by 3,741 · see citing works
Psychopharmacology: The Fourth Generation of Progress
Bloom, F. E., & Kupfer, D. J. (1995) · Medical Entomology and Zoology · Cited by 2,985 · see citing works
Specious reward: A behavioral theory of impulsiveness and impulse control.
Ainslie, G. (1975) · Psychological Bulletin · doi:10.1037/h0076860 · Cited by 2,708 · see citing works
The Organization of Networks within the Orbital and Medial Prefrontal Cortex of Rats, Monkeys and Humans
Ongur, D. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.206 · Cited by 2,627 · see citing works
Exploring the Central Executive
Baddeley, A. (1996) · The Quarterly Journal of Experimental Psychology Section A · doi:10.1080/713755608 · Cited by 2,390 · see citing works
An adjusting procedure for studying delayed reinforcement.
Mazur, J. E. (1987) · doi:10.4324/9781315825502-11 · Cited by 2,189 · see citing works
Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex
Cardinal, R. N., Parkinson, J. A., Hall, J., & Everitt, B. J. (2002) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(02)00007-6 · Cited by 2,129 · see citing works
Self-citation
Varieties of impulsivity
Evenden, J. L. (1999) · Psychopharmacology · doi:10.1007/pl00005481 · Cited by 2,044 · see citing works
The prefontral cortex and cognitive control
Miller, E. K. (2000) · Nature Reviews Neuroscience · doi:10.1038/35036228 · Cited by 2,016 · see citing works
Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans
Aron, A. R., Fletcher, P. C., Bullmore, E. T., Sahakian, B. J., & Robbins, T. W. (2003) · Nature Neuroscience · doi:10.1038/nn1003 · Cited by 1,771 · see citing works
Self-citation
Modulation of memory fields by dopamine Dl receptors in prefrontal cortex
Williams, G. V., & Goldman-Rakic, P. S. (1995) · Nature · doi:10.1038/376572a0 · Cited by 1,593 · see citing works
Goal-directed instrumental action: contingency and incentive learning and their cortical substrates
Balleine, B. W., & Dickinson, A. (1998) · Neuropharmacology · doi:10.1016/s0028-3908(98)00033-1 · Cited by 1,541 · see citing works
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527 · see citing works
Self-citation
Cognitive Deficit Caused by Regional Depletion of Dopamine in Prefrontal Cortex of Rhesus Monkey
Brozoski, T. J., Brown, R. M., Rosvold, H. E., & Goldman, P. S. (1979) · Science · doi:10.1126/science.112679 · Cited by 1,500 · see citing works
Impulsivity and cigarette smoking: delay discounting in current, never, and ex-smokers
Bickel, W. K., Odum, A. L., & Madden, G. J. (1999) · Psychopharmacology · doi:10.1007/pl00005490 · Cited by 1,433 · see citing works
Medial Frontal Cortex Mediates Perceptual Attentional Set Shifting in the Rat
Birrell, J. M., & Brown, V. J. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04320.2000 · Cited by 1,421 · see citing works
The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry
Robbins, T. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1154-7 · Cited by 1,282 · see citing works
Self-citation
Actions and habits: The development of behavioural autonomy
Dickinson, A. (1985) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1985.0010 · Cited by 1,217 · see citing works
Psychopharmacology: The Fourth Generation of Progress
Green, A. I. (1996) · Psychiatric Services · doi:10.1176/ps.47.3.312 · Cited by 1,151 · see citing works
Nonrepinephrine-containing locus coeruleus neurons in behaving rats exhibit pronounced responses to non-noxious environmental stimuli
Aston-Jones, G., & Bloom, F. (1981) · Journal of Neuroscience · doi:10.1523/jneurosci.01-08-00887.1981 · Cited by 1,033 · see citing works
Motivational control of goal-directed action
Dickinson, A., & Balleine, B. (1994) · Animal Learning & Behavior · doi:10.3758/bf03199951 · Cited by 995 · see citing works
Contemporary Animal Learning Theory.
Abrahamson, D. (1981) · Europe PMC (PubMed Central) · Cited by 945 · see citing works
Impulsive choice induced in rats by lesions of the nucleus accumbens core
Cardinal, R. N., Pennicott, D. R., Lakmali, C., Sugathapala, Robbins, T. W., & Everitt, B. J. (2001) · Science · doi:10.1126/science.1060818 · Cited by 923 · see citing works
Self-citation
Measures of impulsivity in cigarette smokers and non-smokers
Mitchell, S. H. (1999) · Psychopharmacology · doi:10.1007/pl00005491 · Cited by 911 · see citing works
Role of locus coeruleus in attention and behavioral flexibility
Aston-Jones, G., Rajkowski, J., & Cohen, J. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00140-7 · Cited by 900 · see citing works
Extinction of emotional learning: contribution of medial prefrontal cortex
Morgan, M. A., Romanski, L. M., & LeDoux, J. E. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90241-c · Cited by 897 · cited 1× · see citing works
“[91] Morgan MA, Romanski LM, LeDoux JE.”
Contemporary Animal Learning Theory
LoLordo, V. M., & Dickinson, A. (1982) · The American Journal of Psychology · doi:10.2307/1422669 · Cited by 891 · see citing works
Untitled work
(1964) · McGraw-Hill eBooks · Cited by 838 · see citing works
The Theory of reinforcement schedules
SCHOENFELD, W. N. (1970) · Appleton-Century-Crofts eBooks · Cited by 799 · see citing works
Supranormal Stimulation of D<sub>1</sub>Dopamine Receptors in the Rodent Prefrontal Cortex Impairs Spatial Working Memory Performance
Zahrt, J., Taylor, J. R., Mathew, R. G., & Arnsten, A. F. T. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08528.1997 · Cited by 796 · see citing works
Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity
Iversen, S., & Mishkin, M. (1970) · Experimental Brain Research · doi:10.1007/bf00237911 · Cited by 765 · see citing works
Coordination of Actions and Habits in the Medial Prefrontal Cortex of Rats
Killcross, S. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.4.400 · Cited by 748 · see citing works
Effects of lesions to ascending noradrenergic neurones on performance of a 5-choice serial reaction task in rats; implications for theories of dorsal noradrenergic bundle function based on selective attention and arousal
Carli, M., Robbins, T. W., Evenden, J. L., & Everitt, B. J. (1983) · Behavioural Brain Research · doi:10.1016/0166-4328(83)90138-9 · Cited by 736 · see citing works
Self-citation
Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats.
Morgan, M. A., & LeDoux, J. E. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.4.681 · Cited by 717 · see citing works
Contrasting Roles of Basolateral Amygdala and Orbitofrontal Cortex in Impulsive Choice
Winstanley, C. A., Theobald, D. E. H., Cardinal, R. N., & Robbins, T. W. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.5606-03.2004 · Cited by 675 · see citing works
Self-citation
Do Rats Have Prefrontal Cortex? The Rose-Woolsey-Akert Program Reconsidered
Preuss, T. M. (1995) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1995.7.1.1 · Cited by 666 · see citing works
The pharmacology of impulsive behaviour in rats: the effects of drugs on response choice with varying delays of reinforcement
Evenden, J. L., & Ryan, C. N. (1996) · Psychopharmacology · doi:10.1007/s002130050121 · Cited by 636 · see citing works
Isolation of an internal clock.
Roberts, S. (1981) · Journal of Experimental Psychology Animal Behavior Processes · doi:10.1037/0097-7403.7.3.242 · Cited by 635 · see citing works
Variations in the Sensitivity of Instrumental Responding to Reinforcer Devaluation
Adams, C. D. (1982) · The Quarterly Journal of Experimental Psychology Section B · doi:10.1080/14640748208400878 · Cited by 635 · see citing works
Frontal Granular Cortex and Behavior.
Orbach, J. (1964) · Archives of General Psychiatry · doi:10.1001/archpsyc.1964.01720300109016 · Cited by 627 · see citing works
Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys
Murphy, B. L., Arnsten, A. F., Goldman-Rakic, P. S., & Roth, R. H. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1325 · Cited by 590 · see citing works
Executive frontal functions
Fuster, J. M. (2000) · Experimental Brain Research · doi:10.1007/s002210000401 · Cited by 558 · see citing works
Dissociable Forms of Inhibitory Control within Prefrontal Cortex with an Analog of the Wisconsin Card Sort Test: Restriction to Novel Situations and Independence from “On-Line” Processing
Dias, R., Robbins, T. W., & Roberts, A. C. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-23-09285.1997 · Cited by 555 · see citing works
Self-citation
Neuromodulation and cortical function: modeling the physiological basis of behavior
Hasselmo, M. E. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(94)00113-t · Cited by 552 · see citing works
Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex
Granon, S., Passetti, F., Thomas, K. L., Dalley, J. W., Everitt, B. J., & Robbins, T. W. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-03-01208.2000 · Cited by 546 · see citing works
Self-citation
Dissociable Contributions of the Orbitofrontal and Infralimbic Cortex to Pavlovian Autoshaping and Discrimination Reversal Learning: Further Evidence for the Functional Heterogeneity of the Rodent Frontal Cortex
Chudasama, Y., & Robbins, T. W. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08771.2003 · Cited by 543 · see citing works
Self-citation
Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity
Chudasama, Y., Passetti, F., Rhodes, S. E. V., Lopian, D., Desai, A., & Robbins, T. W. (2003) · Behavioural Brain Research · doi:10.1016/j.bbr.2003.09.020 · Cited by 518 · see citing works
Self-citation
The Cerebral Cortex of the Rat and Visual Attentional Function: Dissociable Effects of Mediofrontal, Cingulate, Anterior Dorsolateral, and Parietal Cortex Lesions on a Five-Choice Serial Reaction Time Task
Muir, J. L., Everitt, B. J., & Robbins, T. W. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.3.470 · Cited by 503 · see citing works
Self-citation
DETERMINATION OF DISCOUNT FUNCTIONS IN RATS WITH AN ADJUSTING‐AMOUNT PROCEDURE
Richards, J. B., Mitchell, S. H., de Wit, H., & Seiden, L. S. (1997) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1997.67-353 · Cited by 493 · see citing works
Altered reinforcement mechanisms in attention-deficit/hyperactivity disorder.
Sagvolden, T., Aase, H., Zeiner, P., & Berger, D. (1998) · PubMed · Cited by 491 · see citing works
Catecholamine regulation of the prefrontal cortex
Arnsten, A. F. T. (1997) · Journal of Psychopharmacology · doi:10.1177/026988119701100208 · Cited by 489 · see citing works
Functional Specialization within Medial Frontal Cortex of the Anterior Cingulate for Evaluating Effort-Related Decisions
Walton, M. E., Bannerman, D. M., Alterescu, K., & Rushworth, M. F. S. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-16-06475.2003 · Cited by 486 · see citing works
The Prefrontal CortexExecutive and Cognitive Functions
Roberts, A., Robbins, T. W., & Weiskrantz, L. (1998) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780198524410.001.0001 · Cited by 468 · see citing works
Self-citation
Chapter 3 Qualitative and quantitative comparison of the prefrontal cortex in rat and in primates, including humans
Uylings, H. B. M., & van Eden, C. G. (1991) · Progress in brain research · doi:10.1016/s0079-6123(08)62675-8 · Cited by 454 · see citing works
Central 5-HT depletion enhances impulsive responding without affecting the accuracy of attentional performance: interactions with dopaminergic mechanisms
Harrison, A. A., Everitt, B. J., & Robbins, T. W. (1997) · Psychopharmacology · doi:10.1007/s002130050410 · Cited by 452 · see citing works
Self-citation
Immunolesioning: selective destruction of neurons using immunotoxin to rat NGF receptor
Wiley, R. G., Oeltmann, T. N., & Lappi, D. A. (1991) · Brain Research · doi:10.1016/0006-8993(91)91199-b · Cited by 417 · see citing works
The cerebral cortex of the rat
(1991) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(91)90172-9 · Cited by 416 · see citing works
Impulsivity: a discussion of clinical and experimental findings
Evenden, J. L. (1999) · Journal of Psychopharmacology · doi:10.1177/026988119901300211 · Cited by 413 · see citing works
Effects of lesions of the orbitofrontal cortex on sensitivity to delayed and probabilistic reinforcement
S., M., S., B., M.-Y., H., C., B., E., S., J., D., & I., A. (2002) · Psychopharmacology · doi:10.1007/s00213-001-0983-0 · Cited by 409 · see citing works
Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor
Heckers, S., Ohtake, T., Wiley, R. G., Lappi, D., Geula, C., & Mesulam, M. M. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01271.1994 · Cited by 401 · see citing works
Chemical neuromodulation of frontal-executive functions in humans and other animals
Robbins, T. W. (2000) · Experimental Brain Research · doi:10.1007/s002210000407 · Cited by 393 · see citing works
Self-citation
The orbitofrontal cortex and its connections with the mediodorsal nucleus in rabbit, sheep and cat.
ROSE, J. E., & Woolsey, C. N. (1948) · PubMed · Cited by 374 · see citing works
Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex.
Seamans, J. K., Floresco, S., & Phillips, A. G. (1995) · Behavioral Neuroscience · doi:10.1037//0735-7044.109.6.1063 · Cited by 370 · see citing works
The role of rat medial frontal cortex in effort-based decision making
Walton, M. E., Bannerman, D. M., & Rushworth, M. F. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-24-10996.2002 · Cited by 364 · see citing works
Dissociation of the medial prefrontal, posterior parietal, and posterior temporal cortex for spatial navigation and recognition memory in the rat
Kolb, B., Buhrmann, K., McDonald, R., & Sutherland, R. J. (1994) · Cerebral Cortex · doi:10.1093/cercor/4.6.664 · Cited by 362 · see citing works
The amygdala modulates prefrontal cortex activity relative to conditioned fear
Garcia, R., Vouimba, R.-M., Baudry, M., & Thompson, R. F. (1999) · Nature · doi:10.1038/46286 · Cited by 347 · see citing works
Altered reinforcement mechanisms in attention-deficit/hyperactivity disorder
Sagvolden, T., Aase, H., Zeiner, P., & Berger, D. (1998) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00170-8 · Cited by 345 · see citing works
The effects of d -amphetamine, chlordiazepoxide, α-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats
Cardinal, R. N., Robbins, T. W., & Everitt, B. J. (2000) · Psychopharmacology · doi:10.1007/s002130000536 · Cited by 339 · see citing works
Self-citation
The effect of the instrumental training contingency on susceptibility to reinforcer devaluation
Dickinson, A., Nicholas, D. J., & Adams, C. D. (1983) · The Quarterly Journal of Experimental Psychology Section B · doi:10.1080/14640748308400912 · Cited by 338 · see citing works
Animal Learning and Cognition
(1994) · Elsevier eBooks · doi:10.1016/c2009-0-02316-2 · Cited by 325 · see citing works
Functional differences between the prelimbic and anterior cingulate regions of the rat prefrontal cortex.
Seamans, J. K., Floresco, S., & Phillips, A. G. (1995) · Behavioral Neuroscience · doi:10.1037/0735-7044.109.6.1063 · Cited by 324 · see citing works
Rodent models of prefrontal cortical function
Brown, V. J., & Bowman, E. M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02164-1 · Cited by 321 · see citing works
Subchronic Phencyclidine Administration Reduces Mesoprefrontal Dopamine Utilization and Impairs Prefrontal Cortical-Dependent Cognition in the Rat
Jentsch, J. D. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00034-1 · Cited by 320 · see citing works
Disconnection of the anterior cingulate cortex and nucleus accumbens core impairs Pavlovian approach behavior: further evidence for limbic cortical–ventral striatopallidal systems
Parkinson, J. A., Willoughby, P. J., Robbins, T. W., & Everitt, B. J. (2000) · Behavioral Neuroscience · doi:10.1037/0735-7044.114.1.42 · Cited by 314 · see citing works
Self-citation
Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task
McGaughy, J., Dalley, J. W., Morrison, C. H., Everitt, B. J., & Robbins, T. W. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01905.2002 · Cited by 311 · see citing works
Self-citation
The relation of secondary reinforcement to delayed reward in visual discrimination learning.
Grice, G. R. (1948) · Journal of Experimental Psychology · doi:10.1037/h0061016 · Cited by 310 · see citing works
Disconnection of the anterior cingulate cortex and nucleus accumbens core impairs Pavlovian approach behavior: Further evidence for limbic cortical-ventral striatopallidal systems.
Parkinson, J. A., Willoughby, P. J., Robbins, T. W., & Everitt, B. J. (2000) · Behavioral Neuroscience · doi:10.1037//0735-7044.114.1.42 · Cited by 309 · see citing works
Self-citation
Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.
Bussey, T. J., Muir, J. L., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.5.920 · Cited by 301 · see citing works
Self-citation
THE EFFECT OF CONTINGENCY UPON THE APPETITIVE CONDITIONING OF FREE‐OPERANT BEHAVIOR
Hammond, L. J. (1980) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1980.34-297 · Cited by 291 · see citing works
Motivational control after extended instrumental training
Dickinson, A., Balleine, B. W., Watt, A. A., González, F., & Boakes, R. A. (1995) · Animal Learning & Behavior · doi:10.3758/bf03199935 · Cited by 286 · see citing works
A behavioural analysis of rats with damage to the medial prefrontal cortex using the morris water maze: evidence for behavioural flexibility, but not for impaired spatial navigation
de Bruin, J. P. C., Sánchez-Santed, F., Heinsbroek, R. P. W., Donker, A., & Postmes, P. (1994) · Brain Research · doi:10.1016/0006-8993(94)90243-7 · Cited by 285 · see citing works
Attentional functions of the forebrain cholinergic systems: effects of intraventricular hemicholinium, physostigmine, basal forebrain lesions and intracortical grafts on a multiple-choice serial reaction time task
Muir, J. L., Dunnett, S. B., Robbins, T. W., & Everitt, B. J. (1992) · Experimental Brain Research · doi:10.1007/bf00229886 · Cited by 280 · see citing works
Self-citation
Distinct Changes in Cortical Acetylcholine and Noradrenaline Efflux during Contingent and Noncontingent Performance of a Visual Attentional Task
Dalley, J. W., McGaughy, J., O'Connell, M. T., Cardinal, R. N., Levita, L., & Robbins, T. W. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04908.2001 · Cited by 277 · see citing works
Self-citation
The anatomical relationships of the prefrontal cortex with limbic structures and the basal ganglia
Groenewegen, H. J., Wright, C. I., & Uylings, H. B. M. (1997) · Journal of Psychopharmacology · doi:10.1177/026988119701100202 · Cited by 268 · see citing works
Working memory, response selection, and effortful processing in rats with medial prefrontal lesions.
Granon, S., Vidal, C., Thinus‐Blanc, C., Changeux, J., & al, E. (1994) · Behavioral Neuroscience · doi:10.1037//0735-7044.108.5.883 · Cited by 265 · see citing works
Increases in cortical acetylcholine release during sustained attention performance in rats
Himmelheber, A. M., Sarter, M., & Bruno, J. P. (2000) · Cognitive Brain Research · doi:10.1016/s0926-6410(00)00012-4 · Cited by 261 · see citing works
Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat.
Bussey, T. J., Muir, J. L., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037/0735-7044.111.5.920 · Cited by 259 · see citing works
Self-citation
Attention and the frontal cortex as examined by simultaneous temporal processing
Olton, D. S., Wenk, G. L., Church, R. M., & Meck, W. H. (1988) · Neuropsychologia · doi:10.1016/0028-3932(88)90083-8 · Cited by 257 · see citing works
Attention to action
Passingham, R. E. (1996) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1996.0132 · Cited by 236 · see citing works
Impulsivity predicts individual susceptibility to high levels of alcohol self-administration
Poulos, C. X., Le, A. D., & Parker, J. L. (1995) · Behavioural Pharmacology · doi:10.1097/00008877-199512000-00006 · Cited by 234 · cited 1× · see citing works
“It has been considered a normal human characteristic, but impulsive choice contributes to deleterious states such as drug addiction [11,49,65,86,104] and has been suggested to underlie a number of other clinical disorders, including ADHD [116,117].”
Background
Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats
Winstanley, C. A., Chudasama, Y., Dalley, J. W., Theobald, D. E. H., Glennon, J. C., & Robbins, T. W. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1398-x · Cited by 234 · see citing works
Self-citation
Involvement of rodent prefrontal cortex subregions in strategy switching.
Ragozzino, M. E., Wilcox, C., Raso, M., & Kesner, R. P. (1999) · Behavioral Neuroscience · doi:10.1037//0735-7044.113.1.32 · Cited by 231 · see citing works
Sustained Visual Attention Performance-Associated Prefrontal Neuronal Activity: Evidence for Cholinergic Modulation
Gill, T. M., Sarter, M., & Givens, B. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-12-04745.2000 · Cited by 228 · see citing works
Effects of central 5-hydroxytryptamine depletion on sensitivity to delayed and probabilistic reinforcement
Mobini, S., Chiang, T.-J., Ho, M.-Y., Bradshaw, C. M., & Szabadi, E. (2000) · Psychopharmacology · doi:10.1007/s002130000542 · Cited by 228 · see citing works
Delay-dependent modulation of memory retrieval by infusion of a dopamine D₁ agonist into the rat medial prefrontal cortex.
Floresco, S., & Phillips, A. G. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.4.934 · Cited by 225 · see citing works
Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task
Passetti, F., Dalley, J. W., O’Connell, M. T., Everitt, B. J., & Robbins, T. W. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00183.x · Cited by 223 · see citing works
Self-citation
The Frontal Cortex of the Rat and Visual Attentional Performance: Dissociable Functions of Distinct Medial Prefrontal Subregions
Passetti, F. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.12.1254 · Cited by 223 · see citing works
Theory and method in the quantitative analysis of ”impulsive choice” behaviour: implications for psychopharmacology
Ho, M., Mobini, S., Chiang, T.-J., Bradshaw, C., & Szabadi, E. (1999) · Psychopharmacology · doi:10.1007/pl00005482 · Cited by 221 · see citing works
Distinct contributions of glutamate and dopamine receptors to temporal aspects of rodent working memory using a clinically relevant task
Aultman, J. M., & Moghaddam, B. (2000) · Psychopharmacology · doi:10.1007/s002130000590 · Cited by 217 · see citing works
Activation of the noradrenergic system facilitates an attentional shift in the rat
Devauges, V., & Sara, S. J. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90118-x · Cited by 202 · see citing works
Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: Implications for the neurobiology of emotion.
Bussey, T. J., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037//0735-7044.111.5.908 · Cited by 201 · see citing works
Self-citation
Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in rats.
Cardinal, R. N., Parkinson, J. A., Lachenal, G., Halkerston, K. M., Rudarakanchana, N., Hall, J., Morrison, C. H., Howes, S. R., Robbins, T. W., & Everitt, B. J. (2002) · Behavioral Neuroscience · doi:10.1037//0735-7044.116.4.553 · Cited by 201 · see citing works
Self-citation
Prefrontal Cortex and Working Memory for Spatial Response, Spatial Location, and Visual Object Information in the Rat
Kesner, R. P., Hunt, M. E., Williams, J. M., & Long, J. M. (1996) · Cerebral Cortex · doi:10.1093/cercor/6.2.311 · Cited by 201 · see citing works
Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in rats.
Cardinal, R. N., Parkinson, J. A., Lachenal, G., Halkerston, K. M., Rudarakanchana, N., Hall, J., Morrison, C. H., Howes, S. R., Robbins, T. W., & Everitt, B. J. (2002) · Behavioral Neuroscience · doi:10.1037/0735-7044.116.4.553 · Cited by 201 · see citing works
Self-citation
Involvement of rodent prefrontal cortex subregions in strategy switching.
Ragozzino, M. E., Wilcox, C., Raso, M., et al. (1999) · Behavioral Neuroscience · doi:10.1037/0735-7044.113.1.32 · Cited by 201 · see citing works
Instrumental Conditioning
Dickinson, A. (1994) · Animal Learning and Cognition · doi:10.1016/b978-0-08-057169-0.50009-7 · Cited by 200 · see citing works
Working memory, response selection, and effortful processing in rats with medial prefrontal lesions.
Granon, S., Vidal, C., Thinus‐Blanc, C., et al. (1994) · Behavioral Neuroscience · doi:10.1037/0735-7044.108.5.883 · Cited by 197 · see citing works
A comparison of the effects of medial prefrontal, cingulate cortex, and cingulum bundle lesions on tests of spatial memory: evidence of a double dissociation between frontal and cingulum bundle contributions
Aggleton, J., Neave, N., Nagle, S., & Sahgal, A. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-11-07270.1995 · Cited by 196 · see citing works
Cortical cholinergic function and deficits in visual attentional performance in rats following 192 IgG–saporin-induced lesions of the medial prefrontal cortex
Dalley, J. W. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh052 · Cited by 191 · see citing works
Self-citation
Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats measured during behavioural performance of a task assessing visuospatial attention and impulsivity
Dalley, J. W., Theobald, D. E. H., Pereira, E., Li, P., & Robbins, T. W. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1215-y · Cited by 184 · see citing works
Self-citation
Functional role of rat prelimbic-infralimbic cortices in spatial memory: evidence for their involvement in attention and behavioural flexibility
Delatour, B., & Gisquet-Verrier, P. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00168-0 · Cited by 170 · see citing works
Cortical acetylcholine and processing capacity: effects of cortical cholinergic deafferentation on crossmodal divided attention in rats
Turchi, J. N., & Sarter, M. F. (1997) · Cognitive Brain Research · doi:10.1016/s0926-6410(97)00027-x · Cited by 165 · see citing works
Glutamate receptors in the rat medial prefrontal cortex regulate set-shifting ability
Stefani, M. R., Groth, K., & Moghaddam, B. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.4.728 · Cited by 164 · see citing works
Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: Implications for the neurobiology of emotion.
Bussey, T. J., Everitt, B. J., & Robbins, T. W. (1997) · Behavioral Neuroscience · doi:10.1037/0735-7044.111.5.908 · Cited by 163 · see citing works
Self-citation
Electrolytic lesions of the medial prefrontal cortex in rats disrupt performance on an analog of the Wisconsin Card Sorting Test, but do not disrupt latent inhibition: implications for animal models of schizophrenia
Joel, D., Weiner, I., & Feldon, J. (1997) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)87583-3 · Cited by 154 · see citing works
Resolving the contradictions of addiction
Heyman, G. M. (1996) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00042990 · Cited by 152 · see citing works
Choice, behavioral economics, and addiction
Vuchinich, R. E., & Heather, N. (2003) · Cited by 151 · see citing works
Selective ablations within the prefrontal cortex of the rat and performance of delayed alternation
Larsen, J., & Divac, I. (1978) · Physiological Psychology · doi:10.3758/bf03326684 · Cited by 146 · see citing works
Forebrain norepinephrine: role in controlled information processing in the rat.
Cole, B. J., & Robbins, T. W. (1992) · PubMed · Cited by 134 · see citing works
Self-citation
Contribution of Ventrolateral Prefrontal Cortex to the Acquisition and Extinction of Conditioned Fear in Rats
Morgan, M. A., & LeDoux, J. E. (1999) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1999.3907 · Cited by 123 · see citing works
Double dissociation of serotonergic and dopaminergic mechanisms on attentional performance using a rodent five-choice reaction time task
Passetti, F., Dalley, J. W., & Robbins, T. W. (2003) · Psychopharmacology · doi:10.1007/s00213-002-1227-7 · Cited by 121 · see citing works
Self-citation
Subregional analysis of mnemonic functions of the prefrontal cortex in the rat
Kesner, R. P. (2000) · Psychobiology · doi:10.3758/bf03331980 · Cited by 121 · see citing works
Activation of cAMP-Dependent Protein Kinase A in Prefrontal Cortex Impairs Working Memory Performance
Taylor, J. R., Birnbaum, S., Ubriani, R., & Arnsten, A. F. T. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-18-j0001.1999 · Cited by 120 · cited 3× · see citing works
“The prefrontal cortex has been strongly implicated in working memory processes ([5,14,15,34,52,58,70,79,94, 106,118,121,130]; for review see [72]).”
Background
Effects of quinolinic acid-induced lesions of the orbital prefrontal cortex on inter-temporal choice: a quantitative analysis
Kheramin, S., Body, S., Mobini, S., Ho, M.-Y., zquez-Martinez, D. V. X. E., Bradshaw, C. M., Szabadi, E., Deakin, J. F. W., & Anderson, I. M. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1228-6 · Cited by 116 · see citing works
Visual attention in the rat: A role for the prelimbic cortex and thalamic nuclei?
Chudasama, Y., & Muir, J. L. (2001) · Behavioral Neuroscience · doi:10.1037/0735-7044.115.2.417 · Cited by 106 · see citing works
A double dissociation between serial reaction time and radial maze performance in rats subjected to 192 IgG‐saporin lesions of the nucleus basalis and/or the septal region
Lehmann, O., Grottick, A. J., Cassel, J., & Higgins, G. A. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02745.x · Cited by 102 · see citing works
Role of the anterior cingulate cortex in the control over behavior by Pavlovian conditioned stimuli in rats.
Cardinal, R. N., Parkinson, J. A., Marbini, H. D., Toner, A. J., Bussey, T. J., Robbins, T. W., & Everitt, B. J. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.3.566 · Cited by 99 · see citing works
Self-citation
Free-operant acquisition with delayed reinforcement
Dickinson, A., Watt, A. A., & Griffiths, W. J. (2007) · Quarterly Journal of Experimental Psychology · doi:10.1080/14640749208401019 · Cited by 99 · see citing works
Animal learning and cognition
(1995) · Choice Reviews Online · doi:10.5860/choice.32-4482 · Cited by 97 · see citing works
Cholinergic blockade in prefrontal cortex and hippocampus disrupts short-term memory in rats
Dunnett, S. B., Wareham, A. T., & Torres, E. M. (1990) · Neuroreport · doi:10.1097/00001756-199009000-00017 · Cited by 97 · see citing works
Lesions of the prelimbic-infralimbic cortices in rats do not disrupt response selection processes but induce delay-dependent deficits: Evidence for a role in working memory?
Delatour, B., & Gisquest-Verrier, P. (1999) · Behavioral Neuroscience · doi:10.1037//0735-7044.113.5.941 · Cited by 89 · see citing works
Lesions of the prelimbic–infralimbic cortices in rats do not disrupt response selection processes but induce delay-dependent deficits: Evidence for a role in working memory?
Delatour, B., & Gisquest-Verrier, P. (1999) · Behavioral Neuroscience · doi:10.1037/0735-7044.113.5.941 · Cited by 86 · see citing works
The role of the medial prefrontal cortex of rats in short-term memory functioning: further support for involvement of cholinergic, rather than dopaminergic mechanisms
Broersen, L. M., Heinsbroek, R. P. W., de Bruin, J. P. C., Uylings, H. B. M., & Olivier, B. (1995) · Brain Research · doi:10.1016/0006-8993(95)00025-l · Cited by 84 · see citing works
Functional dissociation of the prefrontal cortex and the hippocampus in timing behavior.
Dietrich, A., & Allen, J. D. (1998) · Behavioral Neuroscience · doi:10.1037//0735-7044.112.5.1043 · Cited by 69 · see citing works
The Effects of Muscarinic Cholinergic Receptor Blockade in the Rat Anterior Cingulate and Prelimbic/Infralimbic Cortices on Spatial Working Memory
Ragozzino, M. E., & Kesner, R. P. (1998) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1998.3823 · Cited by 69 · see citing works
Selective immunolesioning of the basal forebrain cholinergic neurons in rats: effect on attention using the 5-choice serial reaction time task
Risbrough, V. B., Bontempi, B., & Menzaghi, F. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1170-7 · Cited by 62 · see citing works
Functional dissociation of the prefrontal cortex and the hippocampus in timing behavior.
Dietrich, A., & Allen, J. D. (1998) · Behavioral Neuroscience · doi:10.1037/0735-7044.112.5.1043 · Cited by 60 · see citing works
The 5-HT2 Receptor Activation Enhances Impulsive Responding Without Increasing Motor Activity in Rats
Koskinen, T., Ruotsalainen, S., & Sirviö, J. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00241-0 · Cited by 58 · see citing works
Involvement of the dorsal anterior cingulate cortex in temporal behavioral sequencing: subregional analysis of the medial prefrontal cortex in rat
Delatour, B. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00251-0 · Cited by 50 · see citing works
Effects of ibotenic acid-induced loss of neurons in the medial prefrontal cortex of rats on behavioral vigilance: evidence for executive dysfunction
Miner, L. A. H., Ostrander, M. M., & Sarter, M. F. (1997) · Journal of Psychopharmacology · doi:10.1177/026988119701100210 · Cited by 47 · see citing works
Choosing Delayed Rewards
Cardinal, R. N., Robbins, T. W., & Everitt, B. J. (2003) · Elsevier eBooks · doi:10.1016/b978-008044056-9/50048-8 · Cited by 31 · see citing works
Self-citation
Mixed attentional and executive deficits in medial frontal cortex lesioned rats
Passetti, F., Humby, T., Everitt, B. J., & Robbins, T. W. (2000) · Psychobiology · doi:10.3758/bf03331984 · Cited by 21 · see citing works
Self-citation
Frontal lesions do not alter the differential extinction of taste aversion conditioning in rats, when using two methods of sucrose delivery
Fresquet, N., Yamamoto, J., & Sandner, G. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00317-0 · Cited by 9 · see citing works
Corrigendum to “Dissociable aspects of performance on the 5-choice serial reaction time task following lesions of the dorsal anterior cingulate, infralimbic and orbitofrontal cortex in the rat: differential effects on selectivity, impulsivity and compulsivity”
Chudasama, Y., Passetti, F., Rhodes, S. E. V., Lopian, D., Desai, A. M., & Robbins, T. W. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.03.014 · Cited by 7 · see citing works
Self-citation

Flagged first, then by citations

Sorted by citations

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
Everitt, B. J., & Robbins, T. W. (2005) · Nature Neuroscience · doi:10.1038/nn1579 · Cited by 3,785 · see citing works
Self-citation
The role of the basal ganglia in habit formation
Yin, H. H., & Knowlton, B. J. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1919 · Cited by 2,402 · see citing works
Prefrontal cortex in the rat: Projections to subcortical autonomic, motor, and limbic centers
Gabbott, P. L. A., Warner, T. A., Jays, P. R. L., Salway, P., & Busby, S. J. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20738 · Cited by 1,227 · see citing works
The ascent of mouse: advances in modelling human depression and anxiety
Cryan, J. F., & Holmes, A. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1825 · Cited by 1,198 · see citing works
The long-term behavioural consequences of prenatal stress
Weinstock, M. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.03.002 · Cited by 1,045 · see citing works
Insights into the neural basis of response inhibition from cognitive and clinical neuroscience
Chambers, C. D., Garavan, H., & Bellgrove, M. A. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.016 · Cited by 938 · see citing works
Neuroendocrinology of coping styles: Towards understanding the biology of individual variation
Koolhaas, J. M., de Boer, S. F., Coppens, C. M., & Buwalda, B. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.04.001 · Cited by 883 · see citing works
Prefrontal–hippocampal interactions in episodic memory
Eichenbaum, H. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.74 · Cited by 870 · see citing works
Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders
Fone, K. C. F., & Porkess, M. V. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.03.003 · Cited by 864 · see citing works
Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat
Vertes, R. P. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.06.027 · Cited by 811 · see citing works
Recognition memory for objects, place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex
Barker, G. R. I., Bird, F., Alexander, V., & Warburton, E. C. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.5289-06.2007 · Cited by 691 · see citing works
Spatial organization of direct hippocampal field CA1 axonal projections to the rest of the cerebral cortex
Cenquizca, L. A., & Swanson, L. W. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.05.002 · Cited by 640 · see citing works
Amygdala and nucleus accumbens in responses to receipt and omission of gains in adults and adolescents.
Ernst, M., Nelson, E. E., Jazbec, S., McClure, E. B., Monk, C. S., Leibenluft, E., Blair, J., & Pine, D. S. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2004.12.038 · Cited by 635 · see citing works
A Neural Circuit for Memory Specificity and Generalization
Xu, W., & Südhof, T. C. (2013) · Science · doi:10.1126/science.1229534 · Cited by 634 · see citing works
Intergenerational transmission of self-regulation: A multidisciplinary review and integrative conceptual framework.
Bridgett, D. J., Burt, N. M., Edwards, E. S., & Deater-Deckard, K. D. (2015) · Psychological Bulletin · doi:10.1037/a0038662 · Cited by 637 · see citing works
Methylphenidate Preferentially Increases Catecholamine Neurotransmission within the Prefrontal Cortex at Low Doses that Enhance Cognitive Function
Berridge, C. W., Devilbiss, D. M., Andrzejewski, M. E., Arnsten, A. F. T., Kelley, A. E., Schmeichel, B., Hamilton, C., & Spencer, R. C. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.04.022 · Cited by 617 · see citing works
Coping styles and behavioural flexibility: towards underlying mechanisms
Coppens, C. M., de Boer, S. F., & Koolhaas, J. M. (2010) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2010.0217 · Cited by 610 · see citing works
Stress prompts habit behavior in humans
Schwabe, L., & Wolf, O. T. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0979-09.2009 · Cited by 606 · see citing works
Imaging Response Inhibition in a Stop-Signal Task: Neural Correlates Independent of Signal Monitoring and Post-Response Processing
Ray Li, C.-S., Huang, C., Constable, R. T., & Sinha, R. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.3741-05.2006 · Cited by 600 · see citing works
“One would thus expect the anterior cingulate cortex to participate in a wide variety of cognitive and affective tasks in which inhibitory control assumes an integral position (Schall et al., 2002; Phillips et al., 2003; Dalley et al., 2004; Isomura and Takada, 2004; Nieuwenhuis et al., 2004; Ridderinkhof et al., 2004;…”
Background
Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors
Volkow, N. D., Wang, G.-J., Telang, F., Fowler, J. S., Thanos, P. K., Logan, J., Alexoff, D., Ding, Y.-S., Wong, C., Ma, Y., et al. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.06.002 · Cited by 573 · see citing works
What constitutes the prefrontal cortex?
Carlén, M. (2017) · Science · doi:10.1126/science.aan8868 · Cited by 561 · see citing works
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
Millan, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.006 · Cited by 549 · see citing works
The bright side of being blue: depression as an adaptation for analyzing complex problems.
Andrews, P. W., & Thomson, J. A. (2009) · Psychological Review · doi:10.1037/a0016242 · Cited by 549 · see citing works
The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks
Eagle, D. M., Bari, A., & Robbins, T. W. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1127-6 · Cited by 548 · see citing works
Self-citation
Parallel and interactive learning processes within the basal ganglia: relevance for the understanding of addiction
Belin, D., Jonkman, S., Dickinson, A., Robbins, T. W., & Everitt, B. J. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.09.027 · Cited by 520 · see citing works
Self-citation
A unified framework for addiction: Vulnerabilities in the decision process
Redish, A. D., Jensen, S., & Johnson, A. (2008) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0800472x · Cited by 501 · see citing works
Cognitive ornithology: the evolution of avian intelligence
Emery, N. J. (2005) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2005.1736 · Cited by 479 · see citing works
Vicarious trial and error
Redish, A. D. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.30 · Cited by 462 · see citing works
The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition
Logue, S. F., & Gould, T. J. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.08.007 · Cited by 477 · see citing works
Stress-induced prefrontal reorganization and executive dysfunction in rodents
Holmes, A., & Wellman, C. L. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.11.005 · Cited by 469 · see citing works
Neurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry
Dalley, J. W., Mar, A. C., Economidou, D., & Robbins, T. W. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.12.021 · Cited by 467 · see citing works
Self-citation
Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice
Meyer, U., Nyffeler, M., Yee, B. K., Knuesel, I., & Feldon, J. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.09.012 · Cited by 457 · see citing works
The application of the 5-choice serial reaction time task for the assessment of visual attentional processes and impulse control in rats
Bari, A., Dalley, J. W., & Robbins, T. W. (2008) · Nature Protocols · doi:10.1038/nprot.2008.41 · Cited by 452 · see citing works
Self-citation
Heart rate variability indices as bio-markers of top-down self-regulatory mechanisms: A meta-analytic review
Holzman, J. B., & Bridgett, D. J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.12.032 · Cited by 449 · see citing works
What, If Anything, Is Rodent Prefrontal Cortex?
Laubach, M., Amarante, L. M., Swanson, K., & White, S. R. (2018) · eNeuro · doi:10.1523/eneuro.0315-18.2018 · Cited by 449 · see citing works
The need for speed: an update on methamphetamine addiction
Barr, A. M., Panenka, W. J., MacEwan, G. W., Thornton, A. E., Lang, D. J., Honer, W. G., & Lecomte, T. (2006) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0635 · Cited by 438 · see citing works
The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward.
Humphries, M. D., & Prescott, T. J. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.11.003 · Cited by 414 · see citing works
Stop-Signal Reaction-Time Task Performance: Role of Prefrontal Cortex and Subthalamic Nucleus
Eagle, D. M., Baunez, C., Hutcheson, D. M., Lehmann, O., Shah, A. P., & Robbins, T. W. (2008) · Cerebral Cortex · doi:10.1093/cercor/bhm044 · Cited by 404 · see citing works
Self-citation
Mental workload and neural efficiency quantified in the prefrontal cortex using fNIRS
Causse, M., Chua, Z. K., Peysakhovich, V., del Campo, N., & Matton, N. (2017) · Scientific Reports · doi:10.1038/s41598-017-05378-x · Cited by 402 · see citing works
Irritability in Youths: A Translational Model
Brotman, M. A., Kircanski, K., Stringaris, A. K., Pine, D. S., & Leibenluft, E. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16070839 · Cited by 366 · see citing works
Schizophrenia-Relevant Behavioral Testing in Rodent Models: A Uniquely Human Disorder?
Powell, C. M., & Miyakawa, T. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.008 · Cited by 368 · see citing works
Epidemiology-driven neurodevelopmental animal models of schizophrenia
Meyer, U., & Feldon, J. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.10.018 · Cited by 366 · see citing works
A computational psychiatry approach identifies how alpha-2A noradrenergic agonist Guanfacine affects feature-based reinforcement learning in the macaque
Hassani, S. A., Oemisch, M., Balcarras, M., Westendorff, S., Ardid, S., van der Meer, M. A. A., Tiesinga, P. H. E., & Womelsdorf, T. (2017) · Scientific Reports · doi:10.1038/srep40606 · Cited by 363 · see citing works
Reinforcement Learning in Multidimensional Environments Relies on Attention Mechanisms
Niv, Y., Daniel, R., Geana, A., Gershman, S. J., Leong, Y. C., Radulescu, A., & Wilson, R. C. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.2978-14.2015 · Cited by 362 · see citing works
Similar effects of the selective noradrenaline reuptake inhibitor atomoxetine on three distinct forms of impulsivity in the rat
Robinson, E. S. J., Eagle, D. M., Mar, A. C., Bari, A., Banerjee, G., Jiang, X., Dalley, J. W., & Robbins, T. W. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301487 · Cited by 359 · see citing works
Self-citation
Choosing an animal model for the study of Huntington's disease
Pouladi, M. A., Morton, A. J., & Hayden, M. R. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3570 · Cited by 350 · see citing works
Gender Differences in the Effects of Prenatal Stress on Brain Development and Behaviour
Weinstock, M. (2007) · Neurochemical Research · doi:10.1007/s11064-007-9339-4 · Cited by 349 · see citing works
Developmental trajectories during adolescence in males and females: A cross-species understanding of underlying brain changes
Brenhouse, H. C., & Andersen, S. L. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.04.013 · Cited by 340 · see citing works
Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults
Volkow, N. D., Wang, G., Telang, F., Fowler, J. S., Goldstein, R. Z., Alia‐Klein, N., Logan, J., Wong, C., Thanos, P. K., Ma, Y., et al. (2009) · Obesity · doi:10.1038/oby.2008.469 · Cited by 344 · see citing works
Heterogeneous organization of the locus coeruleus projections to prefrontal and motor cortices
Chandler, D. J., Gao, W.-J., & Waterhouse, B. D. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320827111 · Cited by 341 · see citing works
Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences
Li, Y., Allen, W. E., Thompson, K. R., Tian, Q., Hsueh, B., Ramakrishnan, C., Wang, A.-C., Jennings, J. H., Adhikari, A., Halpern, C. H., et al. (2016) · Cell · doi:10.1016/j.cell.2016.05.010 · Cited by 326 · see citing works
The neurobiology of social play and its rewarding value in rats
Vanderschuren, L. J. M. J., Achterberg, E. J. M., & Trezza, V. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.07.025 · Cited by 329 · see citing works
Noradrenergic modulation of cognitive function in rat medial prefrontal cortex as measured by attentional set shifting capability
Bluhm, M. D. L., & Morilak, D. A. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.09.031 · Cited by 325 · see citing works
Circuit organization of the rodent medial prefrontal cortex
Anastasiades, P. G., & Carter, A. G. (2021) · Trends in Neurosciences · doi:10.1016/j.tins.2021.03.006 · Cited by 314 · see citing works
Individual differences in prefrontal cortex function and the transition from drug use to drug dependence
George, O., & Koob, G. F. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.05.002 · Cited by 312 · see citing works
Beta-adrenergic Modulation of Cognitive Flexibility during Stress
Alexander, J. K., Hillier, A., Smith, R. M., Tivarus, M. E., & Beversdorf, D. Q. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.3.468 · Cited by 306 · see citing works
Cortico-limbic-striatal circuits subserving different forms of cost-benefit decision making
Floresco, S. B., Onge, J. R. S., Ghods-Sharifi, S., & Winstanley, C. A. (2008) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/cabn.8.4.375 · Cited by 305 · see citing works
Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia
Young, J. W., Powell, S. B., Risbrough, V. B., Marston, H. M., & Geyer, M. A. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.02.004 · Cited by 299 · see citing works
Neurobiological mechanisms for the regulation of mammalian sleep–wake behavior: Reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence
Datta, S., & MacLean, R. R. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.02.004 · Cited by 296 · see citing works
Theta Oscillations in the Medial Prefrontal Cortex Are Modulated by Spatial Working Memory and Synchronize with the Hippocampus through Its Ventral Subregion
O’Neill, P.-K., Gordon, J. A., & Sigurdsson, T. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2378-13.2013 · Cited by 294 · see citing works
Lesions of medial prefrontal cortex disrupt the acquisition but not the expression of goal-directed learning.
Ostlund, S. B., & Balleine, B. W. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1921-05.2005 · Cited by 291 · see citing works
Projection-Specific Neuromodulation of Medial Prefrontal Cortex Neurons
Dembrow, N. C., Chitwood, R. A., & Johnston, D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.3644-10.2010 · Cited by 281 · see citing works
Drug addiction: Pathways to the disease and pathophysiological perspectives
Moal, M. L., & Koob, G. F. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.10.006 · Cited by 284 · see citing works
Is there an inhibitory-response-control system in the rat? Evidence from anatomical and pharmacological studies of behavioral inhibition
Eagle, D. M., & Baunez, C. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.003 · Cited by 280 · see citing works
Nucleus accumbens and impulsivity
Başar, K., Sesia, T., Groenewegen, H. J., Steinbusch, H. W. M., Visser-Vandewalle, V. E. R. M., & Temel, Y. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.08.007 · Cited by 276 · see citing works
Double Dissociation between Serotonergic and Dopaminergic Modulation of Medial Prefrontal and Orbitofrontal Cortex during a Test of Impulsive Choice
Winstanley, C. A., Theobald, D. E. H., Dalley, J. W., Cardinal, R. N., & Robbins, T. W. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhi088 · Cited by 279 · see citing works
Self-citation
Changes of spine density and dendritic complexity in the prefrontal cortex in offspring of mothers exposed to stress during pregnancy
Murmu, M. S., Salomon, S., Biala, Y., Weinstock, M., Braun, K., & Bock, J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05024.x · Cited by 278 · see citing works
A hitchhiker's guide to behavioral analysis in laboratory rodents
Sousa, N., Almeida, O. F. X., & Wotjak, C. T. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00228.x · Cited by 273 · see citing works
Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders
Heidbreder, C., & Newman, A. H. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05149.x · Cited by 303 · see citing works
The kynurenine pathway as a therapeutic target in cognitive and neurodegenerative disorders
Stone, T. W., & Darlington, L. G. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12230 · Cited by 272 · see citing works
Projections from basal forebrain to prefrontal cortex comprise cholinergic, GABAergic and glutamatergic inputs to pyramidal cells or interneurons
Henny, P., & Jones, B. E. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06029.x · Cited by 266 · see citing works
Coding for spatial goals in the prelimbic/infralimbic area of the rat frontal cortex
Hok, V., Save, É., Lenck‐Santini, P., & Poucet, B. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407332102 · Cited by 269 · see citing works
Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance
Li, C.-S. R., Luo, X., Yan, P., Bergquist, K. L., & Sinha, R. (2009) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00891.x · Cited by 254 · see citing works
Distributed Network Actions by Nicotine Increase the Threshold for Spike-Timing-Dependent Plasticity in Prefrontal Cortex
Couey, J. J., Meredith, R. M., Spijker, S., Poorthuis, R. B., Smit, A. B., Brussaard, A. B., & Mansvelder, H. D. (2007) · Neuron · doi:10.1016/j.neuron.2007.03.006 · Cited by 253 · see citing works
Cognitive Dysfunction and Anxious-Impulsive Personality Traits Are Endophenotypes for Drug Dependence
Ersche, K. D., Turton, A. J., Chamberlain, S. R., Müller, U., Bullmore, E. T., & Robbins, T. W. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11091421 · Cited by 252 · see citing works
Self-citation
Projections of the medial orbital and ventral orbital cortex in the rat
Hoover, W. B., & Vertes, R. P. (2011) · The Journal of Comparative Neurology · doi:10.1002/cne.22733 · Cited by 251 · see citing works
Obesity diminishes synaptic markers, alters microglial morphology, and impairs cognitive function
Bocarsly, M. E., Fasolino, M., Kane, G. A., LaMarca, E. A., Kirschen, G. W., Karatsoreos, I. N., McEwen, B. S., & Gould, E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511593112 · Cited by 250 · see citing works
To poly(I:C) or not to poly(I:C): Advancing preclinical schizophrenia research through the use of prenatal immune activation models
Meyer, U., & Feldon, J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.01.009 · Cited by 247 · see citing works
Comparing the prefrontal cortex of rats and primates: Insights from electrophysiology
Seamans, J. K., Lapish, C. C., & Durstewitz, D. (2008) · Neurotoxicity Research · doi:10.1007/bf03033814 · Cited by 244 · see citing works
Neural Circuitry of Stress-Induced Insomnia in Rats
Cano, G., Mochizuki, T., & Saper, C. B. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1809-08.2008 · Cited by 242 · see citing works
Ventromedial Prefrontal Cortex Is Obligatory for Consolidation and Reconsolidation of Object Recognition Memory
Akirav, I., & Maroun, M. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj114 · Cited by 240 · see citing works
Behavioral disinhibition requires dopamine receptor activation
van Gaalen, M. M., Brueggeman, R. J., Bronius, P. F. C., Schoffelmeer, A. N. M., & Vanderschuren, L. J. M. J. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0396-1 · Cited by 236 · see citing works
Late prenatal immune activation in mice leads to behavioral and neurochemical abnormalities relevant to the negative symptoms of schizophrenia
Bitanihirwe, B. K., Peleg-Raibstein, D., Mouttet, F., Feldon, J., & Meyer, U. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.129 · Cited by 237 · see citing works
Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress
Hains, A. B., Vu, M. A. T., Maciejewski, P. K., van Dyck, C. H., Gottron, M., & Arnsten, A. F. T. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0908563106 · Cited by 234 · see citing works
Quantitative Analysis of the Expression of Dopamine D1 and D2 Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex
Santana, N., Mengod, G., & Artigas, F. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn134 · Cited by 231 · see citing works
Behavioral control, the medial prefrontal cortex, and resilience
Maier, S. F., Amat, J., Baratta, M. V., Paul, E. D., & Watkins, L. R. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/smaier · Cited by 231 · see citing works
Adolescent development, hypothalamic-pituitary-adrenal function, and programming of adult learning and memory
McCormick, C. M., & Mathews, I. Z. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.09.019 · Cited by 230 · see citing works
Molecular psychiatry of zebrafish
Stewart, A. M., Ullmann, J. F. P., Norton, W., Parker, M. O., Brennan, C. H., Gerlai, R. T., & Kalueff, A. V. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.128 · Cited by 229 · see citing works
Functions of gamma‐band synchronization in cognition: from single circuits to functional diversity across cortical and subcortical systems
Bosman, C. A., Lansink, C. S., & Pennartz, C. M. A. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12606 · Cited by 225 · see citing works
Noradrenergic, but not cholinergic, deafferentation of prefrontal cortex impairs attentional set-shifting
McGaughy, J., Ross, R. S., & Eichenbaum, H. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.064 · Cited by 226 · see citing works
The effects of energy-rich diets on discrimination reversal learning and on BDNF in the hippocampus and prefrontal cortex of the rat
Kanoski, S. E., Meisel, R. L., Mullins, A. J., & Davidson, T. L. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.05.004 · Cited by 226 · see citing works
Differential roles of medial prefrontal subregions in the regulation of drug seeking
Moorman, D. E., James, M. H., McGlinchey, E. M., & Aston‐Jones, G. (2014) · Brain Research · doi:10.1016/j.brainres.2014.12.024 · Cited by 224 · see citing works
The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders
Winstanley, C. A. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01323.x · Cited by 218 · see citing works
Modulators in concert for cognition: Modulator interactions in the prefrontal cortex
Briand, L. A., Gritton, H., Howe, W. M., Young, D. A., & Sarter, M. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.06.007 · Cited by 216 · see citing works
Neuroanatomical Substrates of Rodent Social Behavior: The Medial Prefrontal Cortex and Its Projection Patterns
Ko, J. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00041 · Cited by 212 · see citing works
Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia
Lodge, D. J., & Grace, A. A. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.01.031 · Cited by 215 · see citing works
Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat
Swanson, C. J., Perry, K. W., Koch-Krueger, S., Katner, J., Svensson, K. A., & Bymaster, F. P. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.11.022 · Cited by 214 · see citing works
The neurobiology of oppositional defiant disorder and conduct disorder: Altered functioning in three mental domains
Matthys, W., Vanderschuren, L. J. M. J., & Schutter, D. J. L. G. (2012) · Development and Psychopathology · doi:10.1017/s0954579412000272 · Cited by 212 · see citing works
Parallel maturation of goal-directed behavior and dopaminergic systems during adolescence
Naneix, F., Marchand, A. R., Di Scala, G., Pape, J.-R., & Coutureau, E. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3080-12.2012 · Cited by 209 · see citing works
Removal of Perineuronal Nets in the Medial Prefrontal Cortex Impairs the Acquisition and Reconsolidation of a Cocaine-Induced Conditioned Place Preference Memory
Slaker, M., Churchill, L., Todd, R. P., Blacktop, J. M., Zuloaga, D. G., Raber, J., Darling, R. A., Brown, T. E., & Sorg, B. A. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3592-14.2015 · Cited by 208 · see citing works

Review Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
Dalley, J. W., Cardinal, R. N., Robbins, T. W., & Serotonin, A. (2013)
Self-citation
An analysis of rat prefrontal cortex in mediating executive function
Kesner, R. P., & Churchwell, J. C. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.07.002 · Cited by 365 · see citing works
The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics
Heidbreder, C. A., & Groenewegen, H. J. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2003.09.003 · Cited by 882 · see citing works
Subregional analysis of mnemonic functions of the prefrontal cortex in the rat
Kesner, R. P. (2000) · Psychobiology · doi:10.3758/bf03331980 · Cited by 121 · see citing works
Anatomical and functional subdivision within the primate lateral prefrontal cortex
Rushworth, M. F. S. (2000) · Psychobiology · doi:10.3758/bf03331977 · Cited by 23 · see citing works

Authors: Dalley, J. W., Cardinal, R. N., & Robbins, T. W.
Affiliations: University of Cambridge (GB)
Corresponding author: Dalley, Jeffrey W.
ORCID: Dalley, Jeffrey W.
Cardinal, Rudolf N.
Robbins, Trevor W.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2004-01
Volume: 28
Issue: 7
Pages: 771-784
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2004.09.006
OpenAlex: W2140549509
Cited by: 1,329
References: 141
Citations by year: 2026: 30 · 2025: 36 · 2024: 39 · 2023: 49 · 2022: 42 · 2021: 59 · 2020: 57 · 2019: 53 · 2018: 80 · 2017: 78 · 2016: 61 · 2015: 79 · 2014: 63 · 2013: 83 · 2012: 79
FWCI: 4.27
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: Wellcome Trust
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: prefrontal cortex, executive function, cognitive function, dorsomedial prefrontal cortex, ventromedial prefrontal cortex, orbitofrontal cortex, anterior cingulate cortex, prelimbic cortex, infralimbic cortex, working memory, decision-making, set-shifting, behavioral flexibility, reversal learning, neuromodulatory systems
MeSH terms: Acetylcholine, Animals, Brain Chemistry, Cognition, Decision Making, Memory, Short-Term, Motor Activity, Norepinephrine, Problem Solving, Reaction Time, Prefrontal Cortex

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks