Nitroxyl (HNO): the Cinderella of the nitric oxide story

The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics

Lundberg, J. O., Weitzberg, E., & Gladwin, M. T. (2008) · Nature Reviews Drug Discovery · doi:10.1038/nrd2466 · Cited by 2,739 · see citing works

The discovery of nitric oxide and its role in vascular biology

Moncada, S., & Higgs, E. A. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706458 · Cited by 863 · see citing works

Vascular Actions of Calcitonin Gene-Related Peptide and Adrenomedullin

Brain, S. D., & Grant, A. D. (2004) · Physiological Reviews · doi:10.1152/physrev.00037.2003 · Cited by 765 · see citing works

Identification of the enzymatic mechanism of nitroglycerin bioactivation

Chen, Z., Zhang, J., & Stamler, J. S. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.122225199 · Cited by 541 · see citing works

Targeting the heme-oxidized nitric oxide receptor for selective vasodilatation of diseased blood vessels

Stasch, J., Schmidt, P. M., Nedvetsky, P. I., Nedvetskaya, T. Y., Kumar, A. H. S., Meurer, S., Deile, M., Taye, A., Knorr, A., Lapp, H., et al. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28371 · Cited by 456 · see citing works

The reduction potential of nitric oxide (NO) and its importance to NO biochemistry

Bartberger, M. D., Liu, W., Ford, E., Miranda, K. M., Switzer, C., Fukuto, J. M., Farmer, P. J., Wink, D. A., & Houk, K. N. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162095599 · Cited by 384 · see citing works

The chemistry of nitroxyl (HNO) and implications in biology

Miranda, K. M. (2005) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2004.08.010 · Cited by 339 · see citing works

Positive inotropic and lusitropic effects of HNO/NO − in failing hearts: Independence from β-adrenergic signaling

Paolocci, N., Katori, T., Champion, H. C., John, M. E. S., Miranda, K. M., Fukuto, J. M., Wink, D. A., & Kass, D. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0937302100 · Cited by 315 · see citing works

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling

Paolocci, N., Saavedra, W. F., Miranda, K. M., Martignani, C., Isoda, T., Hare, J. M., Espey, M. G., Fukuto, J. M., Feelisch, M., Wink, D. A., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.181191198 · Cited by 298 · see citing works

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system

Miranda, K. M., Paolocci, N., Katori, T., Thomas, D. D., Ford, E., Bartberger, M. D., Espey, M. G., Kass, D. A., Feelisch, M., Fukuto, J. M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1430507100 · Cited by 283 · see citing works

The pharmacology of nitroxyl (HNO) and its therapeutic potential: Not just the janus face of NO11This review is dedicated to the career of Prof. Herbert T. Nagasawa, a pioneer in the field of HNO chemistry, biochemistry and pharmacology.

Paolocci, N., Jackson, M. I., Lopez, B., Miranda, K. M., Tocchetti, C. G., Wink, D. A., Hobbs, A. J., & Fukuto, J. M. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.11.002 · Cited by 243 · see citing works

Role of cyclic GMP‐dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes

Layland, J., Li, J., & Shah, A. M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.014126 · Cited by 223 · see citing works

Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca 2+ Cycling

Tocchetti, C. G., Wang, W., Froehlich, J. P., Huke, S., Aon, M. A., Wilson, G. M., Benedetto, G. D., O'Rourke, B. P., Gao, W. D., Wink, D. A., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000253904.53601.c9 · Cited by 216 · see citing works

Nitric oxide (NO)‐induced activation of large conductance Ca2+‐dependent K+ channels (BKCa) in smooth muscle cells isolated from the rat mesenteric artery

Mistry, D. K., & Garland, C. J. (1998) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0701940 · Cited by 205 · see citing works

Nitroxyl affords thiol-sensitive myocardial protective effects akin to early preconditioning

Pagliaro, P., Mancardi, D., Rastaldo, R., Penna, C. R. R., Gattullo, D., Miranda, K. M., Feelisch, M., Wink, D. A., Kass, D. A., & Paolocci, N. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)01179-6 · Cited by 199 · see citing works

Opposite effects of nitric oxide and nitroxyl on postischemic myocardial injury

Ma, X. L., Gao, F., Gao-lin, L., Lopez, B. L., Christopher, T. A., Fukuto, J. M., Wink, D. A., & Feelisch, M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.25.14617 · Cited by 168 · see citing works

On the acidity and reactivity of HNO in aqueous solution and biological systems

Bartberger, M. D., Fukuto, J. M., & Houk, K. N. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041481598 · Cited by 167 · see citing works

NO − Activates Soluble Guanylate Cyclase and K v Channels to Vasodilate Resistance Arteries

Irvine, J. C., Favaloro, J. L., & Kemp‐Harper, B. K. (2003) · Hypertension · doi:10.1161/01.hyp.0000072010.54901.de · Cited by 146 · see citing works

Inotropes in the management of acute heart failure

Petersen, J. W., & Felker, G. M. (2008) · Critical Care Medicine · doi:10.1097/01.ccm.0000296273.72952.39 · Cited by 133 · see citing works

Role of Nitric Oxide in Cardiovascular Adaptation to Intermittent Hypoxia

Manukhina, E. B., Downey, H. F., & Mallet, R. T. (2006) · Experimental Biology and Medicine · doi:10.1177/153537020623100401 · Cited by 131 · see citing works

NITROXYL (HNO): Chemistry, Biochemistry, and Pharmacology

Fukuto, J. M., Switzer, C., Miranda, K. M., & Wink, D. A. (2005) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.095959 · Cited by 130 · see citing works

Vascular smooth muscle relaxation mediated by nitric oxide donors: a comparison with acetylcholine, nitric oxide andnitroxyl ion

Wanstall, J. C., Jeffery, T. K., Gambino, A., Lovren, F., & Triggle, C. R. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704269 · Cited by 126 · see citing works

Comparison of the NO and HNO Donating Properties of Diazeniumdiolates: Primary Amine Adducts Release HNO in Vivo

Miranda, K. M., Katori, T., de Holding, C. L. T., Thomas, L., Ridnour, L. A., McLendon, W. J., Cologna, S. M., Dutton, A. S., Champion, H. C., Mancardi, D., et al. (2005) · Journal of Medicinal Chemistry · doi:10.1021/jm050151i · Cited by 126 · see citing works

Hydrolysis of Acyloxy Nitroso Compounds Yields Nitroxyl (HNO)

Sha, X., Isbell, T. S., Patel, R. P., Day, C. S., & King, S. B. (2006) · Journal of the American Chemical Society · doi:10.1021/ja062365a · Cited by 121 · see citing works

Comparison of the reactivity of nitric oxide and nitroxyl with heme proteins

Miranda, K. M., Nims, R. W., Thomas, D. D., Espey, M. G., Citrin, D. E., Bartberger, M. D., Paolocci, N., Fukuto, J. M., Feelisch, M., & Wink, D. A. (2003) · Journal of Inorganic Biochemistry · doi:10.1016/s0162-0134(02)00498-1 · Cited by 120 · see citing works

Discrimination of Nitroxyl and Nitric Oxide by Water-Soluble Mn(III) Porphyrins

Marti, M. A., Bari, S. E., Estrin, D. A., & Doctorovich, F. A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja044632n · Cited by 119 · see citing works

The Chemistry and Biology of Nitroxyl (HNO): A Chemically Unique Species with Novel and Important Biological Activity

Fukuto, J. M., Dutton, A. S., & Houk, K. N. (2004) · ChemBioChem · doi:10.1002/cbic.200400271 · Cited by 112 · see citing works

Induction of Heme Oxygenase 1 by Nitrosative Stress

NAUGHTON, P. J., Foresti, R., Bains, S. K., Hoque, M., Green, C. J., & Motterlini, R. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m203863200 · Cited by 112 · see citing works

Discriminating formation of HNO from other reactive nitrogen oxide species

Donzelli, S., Espey, M. G., Thomas, D. D., Mancardi, D., Tocchetti, C. G., Ridnour, L. A., Paolocci, N., King, S. B., Miranda, K. M., Lazzarino, G., et al. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.10.058 · Cited by 112 · see citing works

Transduction of NO-bioactivity by the red blood cell in sepsis: novel mechanisms of vasodilation during acute inflammatory disease

Crawford, J. H., Chacko, B. K., Pruitt, H. M., Piknova, B., Hogg, N., & Patel, R. P. (2004) · Blood · doi:10.1182/blood-2004-03-0880 · Cited by 111 · see citing works

Nitroxyl Anion Donor, Angeli’s Salt, Does Not Develop Tolerance in Rat Isolated Aortae

Irvine, J. C., Favaloro, J. L., Widdop, R. E., & Kemp‐Harper, B. K. (2007) · Hypertension · doi:10.1161/01.hyp.0000259328.04159.90 · Cited by 111 · see citing works

Efficient Trapping of HNO by Deoxymyoglobin

Sulc, F., Immoos, C. E., Pervitsky, D., & Farmer, P. J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0376184 · Cited by 110 · see citing works

The nitroxyl anion (HNO) is a potent dilator of rat coronary vasculature

Favaloro, J. L., & Kemp‐Harper, B. K. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.11.018 · Cited by 107 · see citing works

Nitroxyl triggers Ca2+ release from skeletal and cardiac sarcoplasmic reticulum by oxidizing ryanodine receptors

Cheong, E., Tumbev, V., Abramson, J. J., Salama, G., & Stoyanovsky, D. A. (2004) · Cell Calcium · doi:10.1016/j.ceca.2004.07.001 · Cited by 107 · see citing works

Nitric oxide (NO•), the only nitrogen monoxide redox form capable of activating soluble guanylyl cyclase

Dierks, E. A., & Burstyn, J. N. (1996) · Biochemical Pharmacology · doi:10.1016/0006-2952(96)00078-0 · Cited by 106 · see citing works

Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm

Wink, D. A., Miranda, K. M., Katori, T., Mancardi, D., Thomas, D. D., Ridnour, L. A., Espey, M. G., Feelisch, M., Colton, C. A., Fukuto, J. M., et al. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00531.2003 · Cited by 98 · see citing works

Differential actions of L‐cysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aorta

Ellis, A., Li, C. G., & Rand, M. J. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703058 · Cited by 95 · see citing works

Nitroxyl increases force development in rat cardiac muscle

Dai, T., Tian, Y., Tocchetti, C. G., Katori, T., Murphy, A. M., Kass, D. A., Paolocci, N., & Gao, W. D. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.129254 · Cited by 94 · see citing works

Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-l-arginine

Donzelli, S., Espey, M. G., Flores-Santana, W., Switzer, C. H., Yeh, G. C., Huang, J., Stuehr, D. J., King, S. B., Miranda, K. M., & Wink, D. A. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.04.036 · Cited by 91 · see citing works

Donors of HNO

Miranda, K. M., Nagasawa, H. T., & Toscano, J. P. (2005) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026054679290 · Cited by 90 · see citing works

Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes

Laskowski, A., Woodman, O. L., CAO, A., Drummond, G. R., Marshall, T. P., Kaye, D. M., & Ritchie, R. H. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.07.006 · Cited by 88 · see citing works

Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite

Miranda, K. M., Yamada, K., Espey, M. G., Thomas, D. D., DeGraff, W., Mitchell, J. B., Krishna, M. C., Colton, C. A., & Wink, D. A. (2002) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(02)00031-0 · Cited by 80 · see citing works

Antioxidant actions of nitroxyl (HNO)

Lopez, B. E., Shinyashiki, M., Han, T. H., & Fukuto, J. M. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.11.015 · Cited by 74 · see citing works

B-Type Natriuretic Peptide Prevents Acute Hypertrophic Responses in the Diabetic Rat Heart

Rosenkranz, A. C., Hood, S. G., Woods, R. L., Dusting, G. J., & Ritchie, R. H. (2003) · Diabetes · doi:10.2337/diabetes.52.9.2389 · Cited by 67 · see citing works

Mass Spectrometric Analysis of Nitroxyl-Mediated Protein Modification: Comparison of Products Formed with Free and Protein-Based Cysteines

Shen, B., & English, A. M. (2005) · Biochemistry · doi:10.1021/bi0507478 · Cited by 66 · see citing works

Calcitonin Gene-Related Peptide In Vivo Positive Inotropy Is Attributable to Regional Sympatho-Stimulation and Is Blunted in Congestive Heart Failure

Katori, T., Hoover, D. B., Ardell, J. L., Helm, R. H., Belardi, D. F., Tocchetti, C. G., Forfia, P. R., Kass, D. A., & Paolocci, N. (2005) · Circulation Research · doi:10.1161/01.res.0000152969.42117.ca · Cited by 64 · see citing works

Effect of nitroxyl on human platelets function

Bermejo, E., Alberto, F., Rosenstein, R. E., Bari, S. E., Lazzari, M. A., & Sáenz, D. A. (2005) · Thrombosis and Haemostasis · doi:10.1160/th05-01-0062 · Cited by 58 · see citing works

Interaction of heme with nitroxyl or nitric oxide amplifies heme oxygenase-1 induction: involvement of the transcription factor Nrf2.

NAUGHTON, P. J., Hoque, M., Green, C. J., Foresti, R., & Motterlini, R. (2002) · PubMed · Cited by 57 · see citing works

Examining Nitroxyl in Biological Systems

Fukuto, J. M., Jackson, M. I., Kaludercic, N., & Paolocci, N. (2008) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(07)00826-9 · Cited by 48 · see citing works

Xerogel Optical Sensor Films for Quantitative Detection of Nitroxyl

Dobmeier, K. P., Riccio, D. A., & Schoenfisch, M. H. (2008) · Analytical Chemistry · doi:10.1021/ac702024t · Cited by 46 · see citing works

Oxidation of nitroxyl anion to nitric oxide by copper ions

Nelli, S., Hillen, M., Büyükafşar, K., & Martin, W. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703550 · Cited by 44 · see citing works

Dexamethasone attenuates neutrophil infiltration in the rat kidney in ischemia/reperfusion injury: the possible role of nitroxyl

TAKAHIRA, R., Yonemura, K., Fujise, Y., & Hishida, A. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00658-x · Cited by 42 · see citing works

Effects of agents that inactivate free radical NO (NO•) on nitroxyl anion‐mediated relaxations, and on the detection of NO• released from the nitroxyl anion donor Angeli's salt

Ellis, A., Lu, H. T., Li, C. G., & Rand, M. J. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704287 · Cited by 41 · see citing works

Comparison of the redox forms of nitrogen monoxide with the nitrergic transmitter in the rat anococcygeus muscle

Li, C. G., Karagiannis, J., & Rand, M. J. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702540 · Cited by 39 · see citing works

Inhibition of cgmp mediated relaxation in small rat coronary arteries by block of Ca++ activated K+ channels

Price, J. M., & Hellermann, A. (1997) · Life Sciences · doi:10.1016/s0024-3205(97)00660-7 · Cited by 34 · see citing works

Neurotoxicity of nitroxyl: Insights into HNO and NO biochemical imbalance

Hewett, S. J., Espey, M. G., Uliasz, T. F., & Wink, D. A. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.07.007 · Cited by 33 · see citing works

Comparison of responses to novel nitric oxide donors in the feline pulmonary vascular bed

Witt, B. J. D., Marrone, J. R., Kaye, A. D., Keefer, L. K., & Kadowitz, P. J. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01289-4 · Cited by 31 · see citing works

Nitrergic relaxation in urethral smooth muscle: involvement of potassium channels and alternative redox forms of NO

Costa, G., Labadía, A., Triguero, D., Jiménez, E. G., & García-Pascual, Á. (2001) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s002100100480 · Cited by 30 · see citing works

Formation of Nitroxyl and Hydroxyl Radical in Solutions of Sodium Trioxodinitrate

Ivanova, J., Salama, G., Clancy, R. M., Schor, N. F., Nylander, K. D., & Stoyanovsky, D. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m305544200 · Cited by 25 · see citing works

N-Nitroso Products from the Reaction of Indoles with Angeli's Salt

Peyrot, F., Fernandez, B. O., Bryan, N. S., Feelisch, M., & Ducrocq, C. (2005) · Chemical Research in Toxicology · doi:10.1021/tx050253b · Cited by 22 · see citing works

The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin

He, X., Azarov, I., Jeffers, A. B., Presley, T. D., Richardson, J., King, S. B., Gladwin, M. T., & Kim‐Shapiro, D. B. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.12.038 · Cited by 20 · see citing works

Quantitative analysis of the cardiac fibroblast transcriptome—implications for NO/cGMP signaling

Smolenski, A., Schultess, J., Danielewski, O., García-Arguinzonis, M., Thalheimer, P., Kneitz, S., Walter, U., & Lohmann, S. M. (2003) · Genomics · doi:10.1016/j.ygeno.2003.10.002 · Cited by 20 · see citing works

Oxidation and nitrosylation of oxyhemoglobin by S-nitrosoglutathione via nitroxyl anion

Spencer, N. Y., Patel, N. K., Keszler, Á., & Hogg, N. (2003) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.08.021 · Cited by 17 · see citing works

Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

Huynh, K., Bernardo, B. C., McMullen, J. R., & Ritchie, R. H. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2014.01.003 · Cited by 552 · see citing works

Endothelium-derived hyperpolarising factors and associated pathways: a synopsis

Edwards, G., Félétou, M., & Weston, A. H. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-010-0817-1 · Cited by 360 · see citing works

Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation — a tale of three gases!

Li, L., Hsu, A., & Moore, P. K. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.05.005 · Cited by 331 · see citing works

Role of Nitric Oxide in the Cardiovascular and Renal Systems

Ahmad, A., Dempsey, S. K., Daneva, Z., Azam, M., Li, N., Li, P., & Ritter, J. K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092605 · Cited by 286 · see citing works

Sulfonimidamides in Medicinal and Agricultural Chemistry

Chinthakindi, P. K., Naicker, T., Thota, N., Govender, T., Kruger, H. G., & Arvidsson, P. I. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201610456 · Cited by 271 · see citing works

Direct Detection of Nitroxyl in Aqueous Solution Using a Tripodal Copper(II) BODIPY Complex

Rosenthal, J., & Lippard, S. J. (2010) · Journal of the American Chemical Society · doi:10.1021/ja909148v · Cited by 267 · see citing works

Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy

Wang, S., Gai, L., Chen, Y., Ji, X., Lü, H., & Guo, Z. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00456b · Cited by 214 · see citing works

Capture of NO by a Frustrated Lewis Pair: A New Type of Persistent N‐Oxyl Radical

Cardenas, A. J. P., Culotta, B. J., Warren, T. H., Grimme, S., Stute, A., Fröhlich, R., Kehr, G., & Erker, G. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201101622 · Cited by 195 · see citing works

Nitric Oxide: A Guardian for Vascular Grafts?

de Mel, A., Murad, F., & Seifalian, A. M. (2011) · Chemical Reviews · doi:10.1021/cr200008n · Cited by 187 · see citing works

Cardiac inotropes: current agents and future directions

Hasenfuss, G. P., & Teerlink, J. R. (2011) · European Heart Journal · doi:10.1093/eurheartj/ehr026 · Cited by 172 · see citing works

A tale of two gases: NO and H2S, foes or friends for life?

Kolluru, G. K., Shen, X., & Kevil, C. G. (2013) · Redox Biology · doi:10.1016/j.redox.2013.05.001 · Cited by 168 · see citing works

Signaling and stress: The redox landscape in NOS2 biology

Thomas, D. D., Heinecke, J. L., Ridnour, L. A., Cheng, R. Y., Kesarwala, A. H., Switzer, C. H., McVicar, D. W., Roberts, D. D., Glynn, S., Fukuto, J. M., et al. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.06.002 · Cited by 150 · see citing works

Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl

Yong, Q. C., Hu, L.-F., Wang, S., Huang, D., & Bian, J. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq248 · Cited by 133 · see citing works

Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species

Andina, D., Leroux, J., & Luciani, P. (2017) · Chemistry - A European Journal · doi:10.1002/chem.201702458 · Cited by 131 · see citing works

Beyond H2S and NO Interplay: Hydrogen Sulfide and Nitroprusside React Directly to Give Nitroxyl (HNO). A New Pharmacological Source of HNO

Filipović, M. R., Eberhardt, M. J., Prokopović, V. Z., Mijušković, A., Oreščanin-Dušić, Z., Reeh, P. W., & Ivanović‐Burmazović, I. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm3012036 · Cited by 125 · see citing works

Visualization of nitroxyl (HNO) in vivo via a lysosome-targetable near-infrared fluorescent probe

Jing, X., Yu, F., & Chen, L. (2014) · Chemical Communications · doi:10.1039/c4cc07561g · Cited by 124 · see citing works

A Reductant-Resistant and Metal-Free Fluorescent Probe for Nitroxyl Applicable to Living Cells

Kawai, K., Ieda, N., Aizawa, K., Suzuki, T., Miyata, N., & Nakagawa, H. (2013) · Journal of the American Chemical Society · doi:10.1021/ja404757s · Cited by 119 · see citing works

Sickle cell anemia and vascular dysfunction: The nitric oxide connection

Akinsheye, I., & Klings, E. S. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22195 · Cited by 118 · see citing works

A role for nitroxyl (HNO) as an endothelium‐derived relaxing and hyperpolarizing factor in resistance arteries

Andrews, K. L., Irvine, J. C., Tare, M., Apostolopoulos, J., Favaloro, J. L., Triggle, C. R., & Kemp‐Harper, B. K. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00150.x · Cited by 113 · see citing works

Reductive Phosphine-Mediated Ligation of Nitroxyl (HNO)

Reisz, J. A., Klorig, E. B., Wright, M. W., & King, S. B. (2009) · Organic Letters · doi:10.1021/ol900914s · Cited by 112 · see citing works

Molecular Regulation of Tumor Angiogenesis and Perfusion via Redox Signaling

Miller, T. W., Isenberg, J. S., & Roberts, D. D. (2009) · Chemical Reviews · doi:10.1021/cr8005125 · Cited by 111 · see citing works

Detection of nitroxyl (HNO) by membrane inlet mass spectrometry

Cline, M. R., Tu, C., Silverman, D. N., & Toscano, J. P. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.02.008 · Cited by 104 · see citing works

Potential biological chemistry of hydrogen sulfide (H2S) with the nitrogen oxides

Bruce King, S. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.11.005 · Cited by 103 · see citing works

A fast-response, highly sensitive and selective fluorescent probe for the ratiometric imaging of nitroxyl in living cells

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