Regulation of heart function by endogenous gaseous mediators-crosstalk between nitric oxide and hydrogen sulfide

The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener

Zhao, W., Zhang, J., Lu, Y., & Wang, R. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.6008 · Cited by 1,936 · see citing works

Two's company, three's a crowd: can H 2 S be the third endogenous gaseous transmitter?

Wang, R. T. (2002) · The FASEB Journal · doi:10.1096/fj.02-0211hyp · Cited by 1,808 · see citing works

Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators: Diaminofluoresceins

Kojima, H., Nakatsubo, N., Kikuchi, K., Kawahara, S., Kirino, Y., Nagoshi, H., Hirata, Y., & Nagano, T. (1998) · Analytical Chemistry · doi:10.1021/ac9801723 · Cited by 1,391 · see citing works

Myocarditis

Cooper, L. T. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0800028 · Cited by 1,317 · see citing works

The Possible Role of Hydrogen Sulfide as an Endogenous Smooth Muscle Relaxant in Synergy with Nitric Oxide

Hosoki, R., Matsuki, N., & Kimura, H. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6878 · Cited by 1,218 · see citing works

3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

Shibuya, N., Tanaka, M., Yoshida, M., Ogasawara, Y., Togawa, T., Ishii, K., & Kimura, H. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2253 · Cited by 920 · see citing works

Characterization of a Novel, Water-Soluble Hydrogen Sulfide–Releasing Molecule (GYY4137)

Li, L., Whiteman, M., Guan, Y., Neo, K. L., Cheng, Y., Lee, S. W., Zhao, Y., Baskar, R., Tan, C., & Moore, P. K. (2008) · Circulation · doi:10.1161/circulationaha.107.753467 · Cited by 841 · see citing works

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

Calabrese, V., Cornelius, C., Dinkova‐Kostova, A. T., Calabrese, E. J., & Mattson, M. P. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.3074 · Cited by 803 · see citing works

Hydrogen Sulfide Increases Glutathione Production and Suppresses Oxidative Stress in Mitochondria

Kimura, Y., Goto, Y., & Kimura, H. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2282 · Cited by 686 · see citing works

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage

Webb, A., Bond, R., McLean, P., Uppal, R., Benjamin, N., & Ahluwalia, A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402927101 · Cited by 608 · cited 1× · see citing works

Calcium Fluxes Involved in Control of Cardiac Myocyte Contraction

Bers, D. M. (2000) · Circulation Research · doi:10.1161/01.res.87.4.275 · Cited by 581 · see citing works

Nitric Oxide and Cardiac Function

Massion, P. B., Féron, O., Dessy, C., & Balligand, J. (2003) · Circulation Research · doi:10.1161/01.res.0000088351.58510.21 · Cited by 566 · see citing works

The Gasotransmitter Role of Hydrogen Sulfide

Wang, R. T. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603768295249 · Cited by 520 · see citing works

Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol

Geng, B., Chang, L., Pan, C., Qi, Y., Zhao, J., Pang, Y.-Z., Du, J., & Tang, C. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.04.094 · Cited by 399 · see citing works

What is the real physiological NO concentration in vivo?

Hall, C. N., & Garthwaite, J. (2009) · Nitric Oxide · doi:10.1016/j.niox.2009.07.002 · Cited by 378 · see citing works

Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide

Whiteman, M., Li, L., Kostetski, I., Chu, S. H., Siau, J. L., Bhatia, M., & Moore, P. K. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.154 · Cited by 377 · see citing works

The Effect of Hydrogen Sulfide Donors on Lipopolysaccharide-Induced Formation of Inflammatory Mediators in Macrophages

Whiteman, M., Li, L., Rose, P. E., Tan, C., Parkinson, D. B., & Moore, P. K. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2899 · Cited by 367 · see citing works

Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide?

Ali, M. Y., Ping, C. Y., Mok, Y.-Y. P., Ling, L. H., Whiteman, M., Bhatia, M., & Moore, P. K. (2006) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706906 · Cited by 349 · see citing works

H2S generated by heart in rat and its effects on cardiac function

Geng, B., Yang, J., Qi, Y., Zhao, J., Pang, Y.-Z., Du, J., & Tang, C. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.130 · Cited by 342 · see citing works

Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation — a tale of three gases!

Li, L., Hsu, A., & Moore, P. K. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.05.005 · Cited by 331 · see citing works

Nitroxyl (HNO): the Cinderella of the nitric oxide story

Irvine, J. C., Ritchie, R. H., Favaloro, J. L., Andrews, K. L., Widdop, R. E., & Kemp-Harper, B. K. (2008) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2008.08.005 · Cited by 277 · see citing works

The Relationship Between Charge Movements Associated with I Ca and I Na-Ca in Cardiac Myocyte

Bridge, J. H. B., Smolley, J. R., & Spitzer, K. W. (1990) · Science · doi:10.1126/science.2158147 · Cited by 276 · see citing works

Hydrogen sulfide and the vasculature: a novel vasculoprotective entity and regulator of nitric oxide bioavailability?

Whiteman, M., & Moore, P. K. (2009) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2009.00645.x · Cited by 261 · see citing works

The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase

Zhong, G., Chen, F., Cheng, Y., Tang, C., & Du, J. (2003) · Journal of Hypertension · doi:10.1097/00004872-200310000-00015 · Cited by 258 · see citing works

Low Increase in cGMP Induced by Organic Nitrates and Nitrovasodilators Improves Contractile Response of Rat Ventricular Myocytes

Kojda, G., Kottenberg, K., Nix, P., Schlüter, K. D., Piper, H. M., & Noack, E. (1996) · Circulation Research · doi:10.1161/01.res.78.1.91 · Cited by 258 · see citing works

GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat

Li, L., Salto‐Tellez, M., Tan, C., Whiteman, M., & Moore, P. K. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.04.014 · Cited by 244 · see citing works

Cardiomyocyte-Specific Overexpression of Nitric Oxide Synthase 3 Improves Left Ventricular Performance and Reduces Compensatory Hypertrophy After Myocardial Infarction

Janssens, S. P., Pokreisz, P., Schoonjans, L., Pellens, M., Vermeersch, P., Tjwa, M., Jans, P., Scherrer‐Crosbie, M., Picard, M. H., Szelid, Z., et al. (2004) · Circulation Research · doi:10.1161/01.res.0000126497.38281.23 · Cited by 231 · see citing works

Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice

Jones, S. P., Greer, J. J. M., van Haperen, R., Duncker, D. J., de Crom, R., & Lefer, D. J. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0837428100 · Cited by 229 · see citing works

Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca 2+ Cycling

Tocchetti, C. G., Wang, W., Froehlich, J. P., Huke, S., Aon, M. A., Wilson, G. M., Benedetto, G. D., O'Rourke, B. P., Gao, W. D., Wink, D. A., et al. (2006) · Circulation Research · doi:10.1161/01.res.0000253904.53601.c9 · Cited by 216 · see citing works

Endogenous hydrogen sulfide contributes to the cardioprotection by metabolic inhibition preconditioning in the rat ventricular myocytes

Pan, T., Feng, Z.-N., Lee, S. W., Moore, P. K., & Bian, J. (2005) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2005.10.003 · Cited by 196 · see citing works

Physiological and pharmacological features of the novel gasotransmitter: Hydrogen sulfide

Mancardi, D., Penna, C. R. R., Merlino, A., Soldato, P. D., Wink, D. A., & Pagliaro, P. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.03.005 · Cited by 184 · see citing works

Hydrogen sulphide is an inhibitor of L-type calcium channels and mechanical contraction in rat cardiomyocytes

Sun, Y., Cao, Y., Wang, W., Ma, S., Yao, T., & Zhu, Y. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn140 · Cited by 162 · see citing works

Hydrogen sulfide: a new EDRF

Wang, R. (2009) · Kidney International · doi:10.1038/ki.2009.221 · Cited by 156 · see citing works

Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning

Yong, Q. C., Lee, S. W., Foo, C. S., Neo, K. L., Chen, X., & Bian, J. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00244.2008 · Cited by 126 · see citing works

H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes

Pan, T., Neo, K. L., Hu, L., Yong, Q. C., & Bian, J. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00282.2007 · Cited by 114 · see citing works

Species differences in the activity of the Na(+)‐Ca2+ exchanger in mammalian cardiac myocytes.

Sham, J. S. K., Hatem, S. N., & Morad, M. (1995) · The Journal of Physiology · doi:10.1113/jphysiol.1995.sp020995 · Cited by 111 · see citing works

Frequency-Dependent Activation of a Constitutive Nitric Oxide Synthase and Regulation of Contractile Function in Adult Rat Ventricular Myocytes

Kaye, D. M., Wiviott, S. D., Balligand, J., Simmons, W. W., Smith, T. W., & Kelly, R. A. (1996) · Circulation Research · doi:10.1161/01.res.78.2.217 · Cited by 101 · see citing works

Vertebrate phylogeny of hydrogen sulfide vasoactivity

Dombkowski, R. A., Russell, M. J., Schulman, A. A., Doellman, M. M., & Olson, K. R. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00324.2004 · Cited by 97 · see citing works

Acute Effects of Nitric Oxide and Cyclic GMP on Human Myocardial Contractility

Flesch, M., Kilter, H., Cremers, B., Lenz, O., Südkamp, M., Kuhn‐Régnier, F., & Böhm, M. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36716-3 · Cited by 97 · see citing works

Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection

Wang, X., Wang, Q., Guo, W., & Zhu, Y. Z. (2010) · Bioscience Reports · doi:10.1042/bsr20100003 · Cited by 96 · see citing works

Differential actions of L‐cysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aorta

Ellis, A., Li, C. G., & Rand, M. J. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703058 · Cited by 95 · see citing works

Direct measurement of nitric oxide release from vascular endothelial cells

Guo, J. P., Murohara, T., Buerke, M., Scalia, R. G., & Lefer, A. M. (1996) · Journal of Applied Physiology · doi:10.1152/jappl.1996.81.2.774 · Cited by 82 · see citing works

Negative regulation of β-adrenergic function by hydrogen sulphide in the rat hearts

Yong, Q. C., Pan, T., Hu, L., & Bian, J. (2008) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.01.007 · Cited by 82 · see citing works

Hydrogen sulfide potentiates interleukin-1β-induced nitric oxide production via enhancement of extracellular signal-regulated kinase activation in rat vascular smooth muscle cells

Jeong, S., Pae, H., Oh, G., Jeong, G., Lee, B.-S., Lee, S., Kim, D. Y., Rhew, H. Y., Lee, K., & Chung, H. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.002 · Cited by 81 · see citing works

Site-Directed Mutagenesis on Human Cystathionine-γ-Lyase Reveals Insights into the Modulation of H2S Production

Huang, S., Chua, J.-H., Yew, W. S., Sivaraman, J., Moore, P. K., Tan, C., & Deng, L. (2009) · Journal of Molecular Biology · doi:10.1016/j.jmb.2009.11.058 · Cited by 56 · see citing works

Comparing the chemical biology of NO and HNO

Flores-Santana, W., Switzer, C., Ridnour, L. A., Basudhar, D., Mancardi, D., Donzelli, S., Thomas, D. D., Miranda, K. M., Fukuto, J. M., & Wink, D. A. (2009) · Archives of Pharmacal Research · doi:10.1007/s12272-009-1805-x · Cited by 50 · see citing works

Signaling Mechanisms That Mediate Nitric Oxide Production Induced by Acetylcholine Exposure and Withdrawal in Cat Atrial Myocytes

Dedkova, E. N., Ji, X., Wang, Y. G., Blatter, L. A., & Lipsius, S. L. (2003) · Circulation Research · doi:10.1161/01.res.0000106133.92737.27 · Cited by 38 · see citing works

L-Cysteine Stimulates Hydrogen Sulfide Synthesis in Myocardium Associated With Attenuation of Ischemia-Reperfusion Injury

Elsey, D. J., Fowkes, R. C., & Baxter, G. F. (2010) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248409357743 · Cited by 37 · see citing works

The shy Angeli and his elusive creature: the HNO route to vasodilation

Paolocci, N., & Wink, D. A. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00243.2009 · Cited by 23 · see citing works

Sodium Nitroprusside Potentiates Hydrogen-Sulfide-Induced Contractions in Body Wall Muscle From a Marine Worm

Julian, D. A., Statile, J. L., Roepke, T. A., & Arp, A. J. (2005) · Biological Bulletin · doi:10.2307/3593137 · Cited by 15 · see citing works

Chemical Biology of H 2 S Signaling through Persulfidation

Filipović, M. R., Živanović, J., Álvarez, B., & Banerjee, R. V. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00205 · Cited by 1,039 · see citing works

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

Eberhardt, M. J., Dux, M., Namer, B., Miljković, J. L., Cordasic, N., Will, C., Kichko, T. I., de la Roche, J., Fischer, M. J. M., Suárez, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms5381 · Cited by 379 · see citing works

Chemical foundations of hydrogen sulfide biology

Li, Q., & Lancaster, J. R. (2013) · Nitric Oxide · doi:10.1016/j.niox.2013.07.001 · Cited by 334 · see citing works

Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

Kashfi, K., & Olson, K. R. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2012.10.019 · Cited by 315 · see citing works

Key bioactive reaction products of the NO/H 2 S interaction are S/N-hybrid species, polysulfides, and nitroxyl

Cortese-Krott, M. M., Kuhnle, G., Dyson, A., Fernandez, B. O., Grman, M., DuMond, J. F., Barrow, M. P., McLeod, G. S., Nakagawa, H., Ondriaš, K., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1509277112 · Cited by 289 · see citing works

Hydrogen sulfide enhances alfalfa (Medicago sativa) tolerance against salinity during seed germination by nitric oxide pathway

Wang, Y., Li, L., Cui, W., Xu, S., Shen, W., & Wang, R. (2011) · Plant and Soil · doi:10.1007/s11104-011-0936-2 · Cited by 284 · see citing works

Roles of hydrogen sulfide and nitric oxide in the alleviation of cadmium-induced oxidative damage in alfalfa seedling roots

Li, L., Wang, Y., & Shen, W. (2012) · BioMetals · doi:10.1007/s10534-012-9551-9 · Cited by 224 · see citing works

Nitric oxide-activated hydrogen sulfide is essential for cadmium stress response in bermudagrass (Cynodon dactylon (L). Pers.)

Shi, H., Ye, T., & Chan, Z. (2013) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2013.11.001 · Cited by 211 · see citing works

Persulfidation (S-sulfhydration) and H2S

Filipović, M. R. (2015) · Handbook of experimental pharmacology · doi:10.1007/978-3-319-18144-8_2 · Cited by 210 · see citing works

Hydrogen sulfide (H2S) signaling in plant development and stress responses

Liu, H., Wang, J., Liu, J., Liu, T., & Xue, S. (2021) · aBIOTECH · doi:10.1007/s42994-021-00035-4 · Cited by 192 · see citing works

The therapeutic potential of hydrogen sulfide: separating hype from hope

Olson, K. R. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00045.2011 · Cited by 182 · see citing works

Hydrogen sulfide, an enhancer of vascular nitric oxide signaling: mechanisms and implications

Szabó, C. (2016) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00282.2016 · Cited by 179 · see citing works

Passive loss of hydrogen sulfide in biological experiments

DeLeon, E. R., Stoy, G. F., & Olson, K. R. (2011) · Analytical Biochemistry · doi:10.1016/j.ab.2011.10.016 · Cited by 176 · see citing works

Hydrogen Sulfide Stimulates Ischemic Vascular Remodeling Through Nitric Oxide Synthase and Nitrite Reduction Activity Regulating Hypoxia‐Inducible Factor‐1α and Vascular Endothelial Growth Factor–Dependent Angiogenesis

Bir, S. C., Kolluru, G. K., McCarthy, P., Shen, X., Pardue, S., Pattillo, C. B., & Kevil, C. G. (2012) · Journal of the American Heart Association · doi:10.1161/jaha.112.004093 · Cited by 162 · see citing works

Nitrosopersulfide (SSNO−) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

Cortese-Krott, M. M., Fernandez, B. O., Santos, J. L. T., Mergia, E., Grman, M., Nagy, P., Kelm, M., Butler, A., & Feelisch, M. (2014) · Redox Biology · doi:10.1016/j.redox.2013.12.031 · Cited by 153 · see citing works

Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System

Nagpure, B. V., & Bian, J. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/6904327 · Cited by 145 · see citing works

Hydrogen Sulfide as an Oxygen Sensor

Olson, K. R. (2015) · Antioxidants & Redox Signaling · doi:10.1089/ars.2014.5930 · Cited by 144 · see citing works

H2S and polysulfide metabolism: Conventional and unconventional pathways

Olson, K. R. (2017) · Biochemical Pharmacology · doi:10.1016/j.bcp.2017.12.010 · Cited by 134 · see citing works

Beyond H2S and NO Interplay: Hydrogen Sulfide and Nitroprusside React Directly to Give Nitroxyl (HNO). A New Pharmacological Source of HNO

Filipović, M. R., Eberhardt, M. J., Prokopović, V. Z., Mijušković, A., Oreščanin-Dušić, Z., Reeh, P. W., & Ivanović‐Burmazović, I. (2013) · Journal of Medicinal Chemistry · doi:10.1021/jm3012036 · Cited by 125 · see citing works

GYY4137, a Novel Water-Soluble, H2S-Releasing Molecule

Rose, P. E., Dymock, B. W., & Moore, P. K. (2015) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2014.11.014 · Cited by 118 · see citing works

Physiological Importance of Hydrogen Sulfide: Emerging Potent Neuroprotector and Neuromodulator

Panthi, S., Chung, H.-J., Jung, J., & Jeong, N. Y. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/9049782 · Cited by 115 · see citing works

On the chemical biology of the nitrite/sulfide interaction

Cortese-Krott, M. M., Fernandez, B. O., Kelm, M., Butler, A. R., & Feelisch, M. (2015) · Nitric Oxide · doi:10.1016/j.niox.2014.12.009 · Cited by 115 · see citing works

Working with “H2S”: Facts and apparent artifacts

Wedmann, R., Bertlein, S., Mačinković, I., Boeltz, S., Miljković, J. L., Munoz, L. E., i, M. H., & Filipović, M. R. (2014) · Nitric Oxide · doi:10.1016/j.niox.2014.06.003 · Cited by 110 · see citing works

Probing the Intracellular Dynamics of Nitric Oxide and Hydrogen Sulfide Using an Activatable NIR II Fluorescence Reporter

Zhu, T., Ren, N., Liu, X., Dong, Y., Wang, R., Gao, J., Sun, J., Zhu, Y., Wang, L., Fan, C., et al. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202015650 · Cited by 106 · see citing works

Ratiometric Visualization of NO/H 2 S Cross-Talk in Living Cells and Tissues Using a Nitroxyl-Responsive Two-Photon Fluorescence Probe

Zhou, Y., Zhang, X., Yang, S., Li, Y., Qing, Z., Zheng, J., Li, J., & Yang, R. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00073 · Cited by 102 · see citing works

An Update on Hydrogen Sulfide and Nitric Oxide Interactions in the Cardiovascular System

Wu, D., Hu, Q., & Zhu, D. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/4579140 · Cited by 100 · see citing works

Saying NO to H2S: A Story of HNO, HSNO, and SSNO–

Ivanović‐Burmazović, I., & Filipović, M. R. (2019) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.8b02592 · Cited by 87 · see citing works

Does Perthionitrite (SSNO–) Account for Sustained Bioactivity of NO? A (Bio)chemical Characterization

Wedmann, R., Zahl, A., Shubina, T. E., Dürr, M., Heinemann, F. W., Bugenhagen, B., Burger, P., Ivanović‐Burmazović, I., & Filipović, M. R. (2015) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.5b00831 · Cited by 82 · see citing works

Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus

Peng, H., Shen, J., Edmonds, K. A., Luebke, J. L., Hickey, A. K., Palmer, L. D., Chang, F. J., Bruce, K. E., Kehl‐Fie, T. E., Skaar, E. P., et al. (2017) · mSphere · doi:10.1128/msphere.00082-17 · Cited by 75 · see citing works

Hydrogen sulfide as a regulator of calcium channels

Munaron, L., Avanzato, D., Moccia, F. D., & Mancardi, D. (2012) · Cell Calcium · doi:10.1016/j.ceca.2012.07.001 · Cited by 71 · see citing works

Synthesis and evaluation of phosphorodithioate-based hydrogen sulfide donors

Park, C., Zhao, Y., Zhu, Z., Pacheco, A., Peng, B., Devarie‐Baez, N. O., Bagdon, P. E., Zhang, H., & Xian, M. (2013) · Molecular BioSystems · doi:10.1039/c3mb70145j · Cited by 65 · see citing works

Novel Angiogenic Activity and Molecular Mechanisms of ZYZ-803, a Slow-Releasing Hydrogen Sulfide–Nitric Oxide Hybrid Molecule

Hu, Q., Wu, D., Ma, F., Yang, S., Tan, B., Xin, H., Gu, X., Chen, X., Chen, S., Mao, Y., et al. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2015.6607 · Cited by 59 · see citing works

Meningeal blood flow is controlled by H2S‐NO crosstalk activating a HNO ‐ TRPA 1‐ CGRP signalling pathway

Dux, M., Will, C., Vogler, B., Filipović, M. R., & Meßlinger, K. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13164 · Cited by 57 · see citing works

Additive cardioprotection by pharmacological postconditioning with hydrogen sulfide and nitric oxide donors in mouse heart: S-sulfhydration vs. S-nitrosylation

Sun, J., Aponte, A. M., Menazza, S., Guček, M., Steenbergen, C., & Murphy, E. (2016) · Cardiovascular Research · doi:10.1093/cvr/cvw037 · Cited by 58 · see citing works

NO, CO and H2S: A trinacrium of bioactive gases in the brain

Siracusa, R., Voltarelli, V. A., Salinaro, A. T., Modafferi, S., Cuzzocrea, S., Calabrese, E. J., Paola, R. D., Otterbein, L. E., & Calabrese, V. (2022) · Biochemical Pharmacology · doi:10.1016/j.bcp.2022.115122 · Cited by 56 · see citing works

Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II

Wu, D., Hu, Q., Tan, B., Rose, P., Zhu, D., & Zhu, Y. Z. (2018) · Redox Biology · doi:10.1016/j.redox.2018.08.008 · Cited by 56 · see citing works

Hybrid Three Dimensionally Printed Paper-Based Microfluidic Platform for Investigating a Cell’s Apoptosis and Intracellular Cross-Talk

Liu, P., Li, B., Fu, L., Huang, Y. L., Man, M., Qi, J., Sun, X., Kang, Q., Shen, D., & Chen, L. (2020) · ACS Sensors · doi:10.1021/acssensors.9b02205 · Cited by 56 · see citing works

Imaging of anti-inflammatory effects of HNO via a near-infrared fluorescent probe in cells and in rat gouty arthritis model

Huang, Y. L., Zhang, X., He, N., Wang, Y., Kang, Q., Shen, D., Yu, F., & Chen, L. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb02494d · Cited by 47 · see citing works

Polydimethylsiloxane Permeability-Based Method for the Continuous and Specific Detection of Hydrogen Sulfide

Faccenda, A., Wang, J., & Mutus, B. (2012) · Analytical Chemistry · doi:10.1021/ac3008863 · Cited by 44 · see citing works

Induction of caveolin-3/eNOS complex by nitroxyl (HNO) ameliorates diabetic cardiomyopathy

Sun, H., Xiong, S., Wu, Z., Cao, L., Zhu, M., Moore, P. K., & Bian, J. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101493 · Cited by 43 · see citing works

HNO suppresses LPS-induced inflammation in BV-2 microglial cells via inhibition of NF-κB and p38 MAPK pathways

Zhou, Y., Wu, Z., Cao, X., Ding, L., Wen, Z., & Bian, J. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.08.007 · Cited by 42 · see citing works

Tailoring gas-releasing nanoplatforms for wound treatment: An emerging approach

Wang, Z., Rong, F., Zhao, L., Li, W., Kaur, K., & Wang, Y. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.139297 · Cited by 42 · see citing works

Novel H2S-NO hybrid molecule (ZYZ-803) promoted synergistic effects against heart failure

Wu, D., Hu, Q., Xiong, Y., Zhu, D., Mao, Y., & Zhu, Y. Z. (2017) · Redox Biology · doi:10.1016/j.redox.2017.11.020 · Cited by 39 · see citing works

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Testai, L., D’Antongiovanni, V., Piano, I., Martelli, A., Citi, V., Duranti, E., Virdis, A., Blandizzi, C., Gargini, C., Breschi, M. C., et al. (2015) · Nitric Oxide · doi:10.1016/j.niox.2015.03.003 · Cited by 35 · see citing works

Role of Hydrogen Sulfide in the Endocrine System

Chen, H., Ngowi, E. E., Qian, L., Li, T., Qin, Y., Zhou, J., Li, K., Ji, X., & Wu, D. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.704620 · Cited by 33 · see citing works

Role of nitroxyl (HNO) in cardiovascular system: From biochemistry to pharmacology

Sun, H., Wu, Z., Cao, L., Zhu, M., Nie, X.-W., Huang, D., Sun, M., & Bian, J. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.104961 · Cited by 32 · see citing works

Interaction among Hydrogen Sulfide and Other Gasotransmitters in Mammalian Physiology and Pathophysiology

Huang, Y., Jin, H., Zhang, H., Tang, C., & Du, J. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-981-16-0991-6_9 · Cited by 31 · see citing works

Bilayer vascular grafts with on-demand NO and H2S release capabilities

Li, P., Liang, F., Wang, L., Jin, D., Shang, Y., Liu, X., Pan, Y., Yuan, J., Shen, J., & Yin, M. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.07.020 · Cited by 30 · see citing works

Hydrogen Sulfide in Paraventricular Nucleus Enhances Sympathetic Activity and Cardiac Sympathetic Afferent Reflex in Chronic Heart Failure Rats

Gan, X.-B., Liu, T., Xiong, X., Chen, W., Zhou, Y., & Zhu, G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050102 · Cited by 30 · see citing works

Endogenous sulfur dioxide deficiency as a driver of cardiomyocyte senescence through abolishing sulphenylation of STAT3 at cysteine 259

Zhang, S., Qiu, B., Lv, B., Guosheng, Y., Tao, Y., Hu, Y., Li, K., Yu, X., Tang, C., Du, J., et al. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103124 · Cited by 29 · see citing works

L‐cysteine/cystathionine‐β‐synthase‐induced relaxation in mouse aorta involves a L‐serine/sphingosine‐1‐phosphate/NO pathway

Mitidieri, E., Gurgone, D., Caiazzo, E., Tramontano, T., Cicala, C., Sorrentino, R., & Bianca, R. D. D. V. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14654 · Cited by 28 · see citing works

Nitric Oxide Reactivity of [2Fe-2S] Clusters Leading to H2S Generation

Tran, C. T., Williard, P. G., & Kim, E. (2014) · Journal of the American Chemical Society · doi:10.1021/ja505415c · Cited by 27 · see citing works

Nitroxyl as a Potential Theranostic in the Cancer Arena

Sun, H., Lee, W.-T., Leng, B., Wu, Z., Yang, Y., & Bian, J. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7904 · Cited by 26 · see citing works

Use of Phosphorodithioate-Based Compounds as Hydrogen Sulfide Donors

Park, C., & Xian, M. (2015) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2014.11.032 · Cited by 26 · see citing works

Surfactant-modulated discriminative sensing of HNO and H2S with a Cu2+-complex-based fluorescent probe

Lv, H.-J., Ma, R., Zhang, X., Li, M., Wang, Y.-T., Wang, S., & Xing, G. (2016) · Tetrahedron · doi:10.1016/j.tet.2016.07.039 · Cited by 25 · see citing works

A ruthenium nitrosyl complex-based highly selective colorimetric sensor for biological H 2 S and H 2 S–NO cross-talk regulated release of NO

Sharma, N., Kumar, V., & Jose, D. A. (2022) · Dalton Transactions · doi:10.1039/d2dt03108f · Cited by 20 · see citing works

Probing the Intracellular Dynamics of Nitric Oxide and Hydrogen Sulfide Using an Activatable NIR II Fluorescence Reporter

Zhu, T., Ren, N., Liu, X., Dong, Y., Wang, R., Gao, J., Sun, J., Zhu, Y. J., Wang, L., Fan, C., et al. (2021) · Angewandte Chemie · doi:10.1002/ange.202015650 · Cited by 20 · see citing works

Interaction between nitric oxide and renal α1-adrenoreceptors mediated vasoconstriction in rats with left ventricular hypertrophyin Wistar Kyoto rats

Ahmad, A., Sattar, M. Z. A., Azam, M., Khan, S. A., Bhatt, O., & Johns, E. J. (2018) · PLoS ONE · doi:10.1371/journal.pone.0189386 · Cited by 18 · see citing works

Thionitrous Acid/Thionitrite and Perthionitrite Intermediates in the “Crosstalk” of NO and H 2 S

Marcolongo, J. P., Zeida, A., Slep, L. D., & Olabe, J. A. (2017) · Advances in inorganic chemistry · doi:10.1016/bs.adioch.2017.02.002 · Cited by 17 · see citing works

Hydrogen Sulphide and Nitric Oxide Cooperate in Cardioprotection Against Ischemia/Reperfusion Injury in Isolated Rat Heart

Üstünova, S., Takır, S., Yılmazer, N., Bulut, H., Altındirek, D., Ng, Ö. H., Tansel, C. D., DOGAN, B. S. U., Özbek, U., Armutak, E. İ., et al. (2020) · In Vivo · doi:10.21873/invivo.12067 · Cited by 16 · see citing works

Cooperative Interactions Between NO and H 2 S: Chemistry, Biology, Physiology, Pathophysiology

Kevil, C. G., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M., & Szabó, C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804273-1.00005-3 · Cited by 15 · see citing works

Self-Assembled Activatable Probes to Monitor Interactive Dynamics of Intracellular Nitric Oxide and Hydrogen Sulfide

Dong, C., Zhu, T., Sun, J., Dong, X., Sun, L., Gu, X., & Zhao, C. (2024) · Analytical Chemistry · doi:10.1021/acs.analchem.3c04513 · Cited by 13 · see citing works

Low molecular thiols, pH and O2 modulate H2S-induced S-nitrosoglutathione decomposition – •NO release

Grman, M., Mišák, A., Jacob, C., Tomaskova, Z. S., Anna Bertova, T. B., Dočolomanský, P., Habala, L., & Ondriaš, K. (2013) · General Physiology and Biophysics · doi:10.4149/gpb_2013026 · Cited by 13 · see citing works

Circulating levels of hydrogen sulphide negatively correlate to nitrite levels in gestational hypertensive and preeclamptic pregnant women

Possomato‐Vieira, J. S., Palei, A. C., Pinto-Souza, C. C., Cavalli, R. D. C., Dias-Junior, C. A., & Sandrim, V. C. (2021) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13534 · Cited by 12 · see citing works

Generation of H2S from Thiol-Dependent NO Reactivity of Model [4Fe-4S] Cluster and Roussin’s Black Anion

Oakley, K., Zhao, Z., Lehane, R. L., Ma, J., & Kim, E. (2021) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.1c01328 · Cited by 12 · see citing works

The Interaction of NO and H2S in Boar Spermatozoa under Oxidative Stress

Kadlec, M., Pintus, E., & Ros‐Santaella, J. L. (2022) · Animals · doi:10.3390/ani12050602 · Cited by 10 · see citing works

Cystathione gamma lyase/Hydrogen Sulphide Pathway Up Regulation Enhances the Responsiveness of α1A and α1B-Adrenoreceptors in the Kidney of Rats with Left Ventricular Hypertrophy

Ahmad, A., Sattar, M. Z. A., Azam, M., Abdulla, M. H., Khan, S. A., Hashmi, F., Abdullah, N. A., & Johns, E. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154995 · Cited by 10 · see citing works

Suppression of phosphorylated MAPK and caspase 3 by carbon dioxide

Xu, Y., Elimban, V., & Dhalla, N. S. (2017) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-017-3073-2 · Cited by 10 · see citing works

Decoding the Interaction Between Nitric Oxide and Hydrogen Sulfide in Stomatal Movement

Scuffi, D., Lamattina, L., & García‐Mata, C. (2016) · Signaling and communication in plants · doi:10.1007/978-3-319-40713-5_13 · Cited by 9 · see citing works

The Influence of Balneotherapy Using Salty Sulfide–Hydrogen Sulfide Water on Selected Markers of the Cardiovascular System: A Prospective Study

Zapolski, T., Kornecki, W., & Jaroszyński, A. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13123526 · Cited by 8 · see citing works

Mechanisms Associated to Nitroxyl (HNO)-Induced Relaxation in the Intestinal Smooth Muscle

Gastreich-Seelig, M., Jiménez, M., & Pouokam, E. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00438 · Cited by 7 · see citing works

Interaction between hydrogen sulfide, nitric oxide, and carbon monoxide pathways in the bovine isolated retina

Chitnis, M. K., Bush, L., Belford, R., Robinson, J., Opere, C. A., Ohia, S. E., & Mbye, Y. F. N. (2019) · AIMS neuroscience · doi:10.3934/neuroscience.2019.3.104 · Cited by 7 · see citing works

Effect of gasotransmitters treatment on expression of hypertension, vascular and cardiac remodeling and hypertensive nephropathy genes in left ventricular hypertrophy

Ahmad, A., Riaz, Z., Sattar, M. Z. A., Khan, S. A., John, E. J., Rashid, S., Shah, S. T. A., Rafiq, M., Azam, M., & Qamar, R. (2020) · Gene · doi:10.1016/j.gene.2020.144479 · Cited by 6 · see citing works

HNO–Thiol Relationship

Filipović, M. R. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800934-5.00006-2 · Cited by 6 · see citing works

Cellular senescence in age-related cardiovascular disease: past and future

Wu, X., Zhou, Q. S., Huang, Y., Jiang, W., Zhou, J., Qian, K., Pan, Y. P., Wu, Z., Zhang, J., Aimaiti, M., et al. (2026) · Frontiers in Aging · doi:10.3389/fragi.2025.1721744 · Cited by 5 · see citing works

Neurogasobiology of migraine: Carbon monoxide, hydrogen sulfide, and nitric oxide as emerging pathophysiological trinacrium relevant to nociception regulation

Badaeva, A. V., Maiolino, L., Ab, D., Наприенко, М. В., Danilov, A. B., Jacob, U. M., & Calabrese, V. (2025) · Open Medicine · doi:10.1515/med-2025-1201 · Cited by 4 · see citing works

HNO/Thiol Biology as a Therapeutic Target

Miljković, J. L., & Filipović, M. R. (2016) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-319-30705-3_14 · Cited by 4 · see citing works

Cardiac mitochondrial proteomic expression in inbred rat strains divergent in survival time after hemorrhage

Klemcke, H. G., DeKroon, R. M., Mocanu, M., Robinette, J. B., & Álzate, Ó. (2013) · Physiological Genomics · doi:10.1152/physiolgenomics.00118.2012 · Cited by 3 · see citing works

Triple Amperometric Microsensor for Simultaneous Real-Time In Vivo Monitoring of NO, CO, and H 2 S During Epileptic Seizures

Yoon, H., Nam, H., Jeong, Y., Suh, M., & Lee, Y. (2025) · ACS Sensors · doi:10.1021/acssensors.5c03130 · Cited by 2 · see citing works

The Interaction of NO and H2S Signaling Systems in Biology and Medicine

Cao, X., & Bian, J. (2018) · Royal Society of Chemistry eBooks · doi:10.1039/9781788013000-00145 · Cited by 2 · see citing works

Hydrogen Sulfide, Reactive Nitrogen Species, and “The Joy of the Experimental Play*”

Cortese-Krott, M. M. (2022) · Wiley eBooks · doi:10.1002/9781119799900.ch4 · Cited by 2 · see citing works

Hydrogen sulfide and nitric oxide crosstalk in plants under stress

Szőllősi, R., Molnár, Á., Feigl, G., Oláh, D., & Kolbert, Z. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85862-5.00011-7 · Cited by 1 · see citing works

Hydrogen Sulfide: Physiological and Pathophysiological Functions

Liu, Y. T., & Bian, J. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1550-3_6

Animal model and therapeutic prospects for left ventricular hypertrophy and associated renal complicationPreprint

Ahmad, A., Riaz, Z., Sattar, M. Z. A., Khan, S. A., John, E. J., Arshad, S., Shah, S. T. A., Rafiq, M., Azam, M., & Qamar, R. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/638353

Different patterns of H2S/NO cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Calderone, V., Testai, L., Martelli, A., Citi, V., D’Antongiovanni, V., & Breschi, M. C. (2015) · Nitric Oxide · doi:10.1016/j.niox.2015.02.075

Hydrogen sulfide interacts with nitric oxide in the heart: possible involvement of nitroxyl

Yong, Q. C., Hu, L.-F., Wang, S., Huang, D., & Bian, J. (2010) · Cardiovascular Research · doi:10.1093/cvr/cvq248 · Cited by 133 · see citing works

Review Article Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System

Nagpure, B. V., & Bian, J.-S. (2015)

Interaction of Hydrogen Sulfide with Nitric Oxide in the Cardiovascular System

Nagpure, B. V., & Bian, J. (2015) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/6904327 · Cited by 145 · see citing works

An Update on Hydrogen Sulfide and Nitric Oxide Interactions in the Cardiovascular System

Wu, D., Hu, Q., & Zhu, D. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/4579140 · Cited by 100 · see citing works

Hydrogen sulfide down-regulation of L-arginine/nitric oxide synthase/NO pathway in aortic tissues of rat

Geng, B. (2005) · Zhongguo yaolixue tongbao · Cited by 1 · see citing works