Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Loane, David J., Faden, Alan I.·2010·Trends in Pharmacological Sciences

Cited by (574)

Items 101–200 of 574

  1. Expression of miRNAs and Their Cooperative Regulation of the Pathophysiology in Traumatic Brain Injury
    Zhonghua Hu, Danni Yu, Camila P. Almeida-Suhett, Kang Tu, Ann M. Marini, Lee E. Eiden, Maria F. M. Braga, Jun Zhu, Zheng Li · 2012 · PLoS ONE
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  3. Gene expression patterns following unilateral traumatic brain injury reveals a local pro-inflammatory and remote anti-inflammatory response
    Todd E. White, Gregory D. Ford, Monique C. Surles-Zeigler, Alicia Gates, Michelle C. LaPlaca, Byron D. Ford · 2013 · BMC Genomics
  4. Progesterone in the treatment of acute traumatic brain injury: a clinical perspective and update
    Donald G. Stein · 2011 · Neuroscience
  5. Interleukin-4 improves white matter integrity and functional recovery after murine traumatic brain injury via oligodendroglial PPARγ
    Hongjian Pu, Xuan Zheng, Xiaoyan Jiang, Hongfeng Mu, Fei Xu, Wen Zhu, Qing Ye, Yunneng Jizhang, T. Kevin Hitchens, Yejie Shi et al. · 2020 · Journal of Cerebral Blood Flow & Metabolism
  6. NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury
    Kebin Xu, Fangfang Wu, Ke Xu, Zhengmao Li, Xiaojie Wei, Qi Lu, Ting Jiang, Fenzan Wu, Xinlong Xu, Jian Xiao et al. · 2018 · Chemico-Biological Interactions
  7. Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury
    Huiling Tang, Fang Hua, Jun Wang, Seema Yousuf, Fahim Atif, Iqbal Sayeed, Donald G. Stein · 2015 · Brain Injury
  8. Military-related mild traumatic brain injury: clinical characteristics, advanced neuroimaging, and molecular mechanisms
    Sharon Y. Kim, Ping‐Hong Yeh, John M. Ollinger, Herman D. Morris, Maureen N. Hood, Vincent B. Ho, Kwang H. Choi · 2023 · Translational Psychiatry
  9. CR8, a Novel Inhibitor of CDK, Limits Microglial Activation, Astrocytosis, Neuronal Loss, and Neurologic Dysfunction after Experimental Traumatic Brain Injury
    Shruti V. Kabadi, Bogdan A. Stoica, David J. Loane, Tao Luo, Alan I. Faden · 2014 · Journal of Cerebral Blood Flow & Metabolism
  10. Low-Level Laser Therapy Effectively Prevents Secondary Brain Injury Induced by Immediate Early Responsive Gene X-1 Deficiency
    Qi Zhang, Chang Zhou, Michael Richard Hamblin, Mei X. Wu · 2014 · Journal of Cerebral Blood Flow & Metabolism
  11. Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain injury in rats
    Ye Xiong, Yanlu Zhang, Asim Mahmood, Yuling Meng, Zheng Gang Zhang, Daniel C. Morris, Michael Chopp · 2012 · Journal of neurosurgery
  12. Extracellular Vesicles Mediate Neuroprotection and Functional Recovery after Traumatic Brain Injury
    Min Kyoung Sun, Austin P. Passaro, Charles-Francois Vincent Latchoumane, Samantha E. Spellicy, Michael Bowler, Morgan Goeden, William J. Martin, Philip V. Holmes, Steven L. Stice, Lohitash Karumbaiah · 2019 · Journal of Neurotrauma
  13. Traumatic brain injury induces neuroinflammation and neuronal degeneration that is associated with escalated alcohol self-administration in rats
    Jacques P. Mayeux, Sophie X. Teng, Paige S. Katz, Nicholas W. Gilpin, Patricia E. Molina · 2014 · Behavioural Brain Research
  14. Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway
    Yan Feng, Junling Gao, Ying Cui, Minghang Li, Ran Li, Changmeng Cui, Jianzhong Cui · 2016 · Cellular and Molecular Neurobiology
  15. Temporal and Spatial Effects of Blast Overpressure on Blood-Brain Barrier Permeability in Traumatic Brain Injury
    Matthew Kuriakose, Kakulavarapu V. Rama Rao, Daniel Younger, Namas Chandra · 2018 · Scientific Reports
  16. Microglia Receptors in Animal Models of Traumatic Brain Injury
    Daniel Younger, Madhuvika Murugan, Kakulavarapu V. Rama Rao, Long‐Jun Wu, Namas Chandra · 2018 · Molecular Neurobiology
  17. Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury
    Carmela Belardo, Monica Iannotta, Serena Boccella, Rosamaria Cristina Rubino, Flavia Ricciardi, Rosmara Infantino, Gorizio Pieretti, Luigi Stella, Salvatore Paino, Ida Marabese et al. · 2019 · Frontiers in Pharmacology
  18. Common Protective Strategies in Neurodegenerative Disease: Focusing on Risk Factors to Target the Cellular Redox System
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  19. Nutritional Treatment for Traumatic Brain Injury
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  20. Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury
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  21. Restoring After Central Nervous System Injuries: Neural Mechanisms and Translational Applications of Motor Recovery
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  22. Therapeutic Effects of Pharmacologically Induced Hypothermia against Traumatic Brain Injury in Mice
    Jin Hwan Lee, Ling Wei, Xiaohuan Gu, Zheng Zachory Wei, Thomas A. Dix, Shan Ping Yu · 2014 · Journal of Neurotrauma
  23. MicroRNA-21 Is a Versatile Regulator and Potential Treatment Target in Central Nervous System Disorders
    Bai, Xue, Bian, Zhigang · 2022 · Frontiers in Molecular Neuroscience
  24. Cyclin D1 Gene Ablation Confers Neuroprotection in Traumatic Brain Injury
    Shruti V. Kabadi, Bogdan A. Stoica, David J. Loane, Kimberly R. Byrnes, Marie Hanscom, Rainier Michael Cabatbat, Ming T. Tan, Alan I. Faden · 2011 · Journal of Neurotrauma
  25. Propranolol and Mesenchymal Stromal Cells Combine to Treat Traumatic Brain Injury
    Daniel J. Kota, Karthik S. Prabhakara, Alexandra J. van Brummen, Supinder Singh Bedi, Hasen Xue, Bryan DiCarlo, Charles S. Cox, Scott D. Olson · 2015 · Stem Cells Translational Medicine
  26. Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E
    Jianjun Zhong, Chongjie Cheng, Han Liu, Zhijian Huang, Yue Wu, Zhipeng Teng, Junchi He, Hongrong Zhang, Jinchuan Wu, Fang Cao et al. · 2016 · Neuroscience
  27. Heat shock protein signaling in brain ischemia and injury
    Jong Youl Kim, Ji Won Kim, Midori Anne Yenari · 2019 · Neuroscience Letters
  28. Voluntary Exercise Preconditioning Activates Multiple Antiapoptotic Mechanisms and Improves Neurological Recovery after Experimental Traumatic Brain Injury
    Zaorui Zhao, Boris E. Sabirzhanov, Junfang Wu, Alan I. Faden, Bogdan A. Stoica · 2014 · Journal of Neurotrauma
  29. In vivo Contributions of BH3-Only Proteins to Neuronal Death Following Seizures, Ischemia, and Traumatic Brain Injury
    Tobías Engel, Nikolaus Plesnila, Jochen H.M. Prehn, David Clifford Henshall · 2011 · Journal of Cerebral Blood Flow & Metabolism
  30. Single Administration of Tripeptide α-MSH(11–13) Attenuates Brain Damage by Reduced Inflammation and Apoptosis after Experimental Traumatic Brain Injury in Mice
    Eva‐Verena Schaible, Arne Steinsträßer, Antje Jahn‐Eimermacher, Clara Luh, Anne Sebastiani, Frida Kornes, Dana Pieter, Michael K. E. Schäfer, Kristin Engelhard, Serge Christian Thal · 2013 · PLoS ONE
  31. Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury
    Yanlu Zhang, Michael Chopp, Yuling Meng, Zheng Gang Zhang, Edith Doppler, Stefan Winter, Timothy J. Schallert, Asim Mahmood, Ye Xiong · 2015 · Journal of neurosurgery
  32. Wnt and lithium: a common destiny in the therapy of nervous system pathologies?
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  33. Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage
    Yun-Hee Bae, Hyejin Joo, Jinhyun Bae, Seung Jae Hyeon, Song Her, Eunhwa Ko, Hwan Geun Choi, Hoon Ryu, Eun‐Mi Hur, Youngmin Bu et al. · 2018 · Cell Death and Disease
  34. Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury
    Alexander V. Glushakov, Sean Robbins, Connor L Bracy, Shuh Narumiya, Sylvain Doré · 2013 · Journal of Neuroinflammation
  35. The Role of Substance P in Secondary Pathophysiology after Traumatic Brain Injury
    Robert Vink, Levon Gabrielian, Emma Thornton · 2017 · Frontiers in Neurology
  36. Palmitoylethanolamide Reduces Neuropsychiatric Behaviors by Restoring Cortical Electrophysiological Activity in a Mouse Model of Mild Traumatic Brain Injury
    Francesca Guida, Serena Boccella, Monica Iannotta, Danilo De Gregorio, Catia Giordano, Carmela Belardo, Rosaria Romano, Enza Palazzo, Maria Antonietta Scafuro, Nicola Serra et al. · 2017 · Frontiers in Pharmacology
  37. Neuroprotective Effects of Trigeminal Nerve Stimulation in Severe Traumatic Brain Injury
    Amrit Chiluwal, Raj K. Narayan, Wayne W. Chaung, Neal D. Mehan, Ping Wang, Chad E. Bouton, Eugene V. Golanov, Chunyan Li · 2017 · Scientific Reports
  38. CR8, a Selective and Potent CDK Inhibitor, Provides Neuroprotection in Experimental Traumatic Brain Injury
    Shruti V. Kabadi, Bogdan A. Stoica, Marie Hanscom, David J. Loane, Giorgi Kharebava, Michael G. Murray II, Rainier Michael Cabatbat, Alan I. Faden · 2011 · Neurotherapeutics
  39. Neuronal damage and functional deficits are ameliorated by inhibition of aquaporin and HIF1α after traumatic brain injury (TBI)
    Mohammed Shenaq, Hassan Kassem, Changya Peng, Steven Schafer, Jamie Y. Ding, Vance L. Fredrickson, Murali Guthikonda, Christian W. Kreipke, José A. Rafols, Yuchuan Ding · 2012 · Journal of the Neurological Sciences
  40. Treadmill Exercise Protects Against Pentylenetetrazol-Induced Seizures and Oxidative Stress after Traumatic Brain Injury
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  41. A clinical/translational perspective: Can a developmental hormone play a role in the treatment of traumatic brain injury?
    Donald G. Stein · 2012 · Hormones and Behavior
  42. Systems Biology Approaches for Discovering Biomarkers for Traumatic Brain Injury
    Jacob Feala, Mohamed Diwan M. AbdulHameed, Chenggang Yu, Bhaskar Dutta, Xueping Yu, Kara E. Schmid, Jitendra R. Dave, Frank C. Tortella, Jaques Reifman A · 2013 · Journal of Neurotrauma
  43. Immuno-suppressive hydrogels enhance allogeneic MSC survival after transplantation in the injured brain
    Melissa Alvarado‐Velez, Syed Faaiz Enam, Nalini Mehta, Johnathan G. Lyon, Michelle C. LaPlaca, Ravi V. Bellamkonda · 2020 · Biomaterials
  44. Effects of GDNF‐Loaded Injectable Gelatin‐Based Hydrogels on Endogenous Neural Progenitor Cell Migration
    Deniece Fon, Aswan Al‐Abboodi, Peggy P. Y. Chan, Kun Zhou, Peter John Crack, David Isaac Finkelstein, John S. Forsythe · 2014 · Advanced Healthcare Materials
  45. Postsynaptic scaffold protein Homer 1a protects against traumatic brain injury via regulating group I metabotropic glutamate receptors
    Peng Luo, T Chen, Yansong Zhao, Liqiang Zhang, Yuefan Yang, W Liu, Shiting Li, Wenlian Rao, Shuhui Dai, J Yang et al. · 2014 · Cell Death and Disease
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  47. Development of a Database for Translational Spinal Cord Injury Research
    Jessica L. Nielson, Cristian F. Guandique, Aiwen W. Liu, Darlene A. Burke, A. Todd Lash, Rod Moseanko, Stephanie Hawbecker, Sarah C. Strand, Sharon Zdunowski, Karen‐Amanda Irvine et al. · 2014 · Journal of Neurotrauma
  48. Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic Hyperexcitability
    Jacques P. Mayeux, Paige S. Katz, Scott Edwards, Jason W. Middleton, Patricia E. Molina · 2016 · Journal of Neurotrauma
  49. Is progesterone a worthy candidate as a novel therapy for traumatic brain injury?
    Donald G. Stein · 2011 · Dialogues in Clinical Neuroscience
  50. AMPK and its Activator Berberine in the Treatment of Neurodegenerative Diseases
    Siru Qin, Huiling Tang, Wei Li, Yinan Gong, Shanshan Li, Jin Huang, Yuxin Fang, Wenjuan Yuan, Yangyang Liu, Shenjun Wang et al. · 2020 · Current Pharmaceutical Design
  51. Dementia resulting from traumatic brain injury
    Joana Ramalho, Maurício Castillo · 2015 · Dementia & Neuropsychologia
  52. Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to mir-195 in traumatic brain injury
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  53. Polydatin alleviates traumatic brain injury: Role of inhibiting ferroptosis
    Lu Hsiang Huang, Shulei He, Qing Cai, Fei Li, Siwei Wang, Kai Tao, Xi Ye, Huaizhou Qin, Guodong Gao, Dayun Feng · 2021 · Biochemical and Biophysical Research Communications
  54. Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury
    Lin Li, Qingqing Luo, Bin Shang, Xiaomin Yang, Yuan Zhang, Qiuling Pan, Na Wu, Wei Tang, Donglin Du, Xiaochuan Sun et al. · 2021 · Experimental Neurology
  55. Caffeic Acid Phenethyl Ester Protects Blood–Brain Barrier Integrity and Reduces Contusion Volume in Rodent Models of Traumatic Brain Injury
    Jing Zhao, Shibani Pati, John B. Redell, Min Zhang, Anthony N. Moore, Pramod K. Dash · 2011 · Journal of Neurotrauma
  56. Angiotensin Receptor Type 2 Activation Induces Neuroprotection and Neurogenesis After Traumatic Brain Injury
    Gali Umschweif, Sigal Liraz Zaltsman, Dalia Shabashov, Alexander G. Alexandrovich, Victoria Trembovler, Michal Horowitz, Esther Shohami · 2014 · Neurotherapeutics
  57. Delayed Administration of BQ788, an ET B Antagonist, after Experimental Traumatic Brain Injury Promotes Recovery of Blood–Brain Barrier Function and a Reduction of Cerebral Edema in Mice
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  58. Significant changes in circular RNA in the mouse cerebral cortex around an injury site after traumatic brain injury
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  59. Neuroimaging of Traumatic Brain Injury
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  61. Improvement in functional recovery with administration of Cerebrolysin after experimental closed head injury
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  62. Challenging the Role of Adaptive Immunity in Neurotrauma: Rag1 −/− Mice Lacking Mature B and T Cells Do Not Show Neuroprotection after Closed Head Injury
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  64. Parvalbumin immunoreactivity and expression of GABAA receptor subunits in the thalamus after experimental TBI
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  90. Nanoparticle-based drug delivery for the treatment of traumatic brain injury
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  92. Phosphorylation of connexin 43 induced by traumatic brain injury promotes exosome release
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  93. Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression
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  95. Xenon treatment after severe traumatic brain injury improves locomotor outcome, reduces acute neuronal loss and enhances early beneficial neuroinflammation: a randomized, blinded, controlled animal study
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  99. Recent developments in clinical trials for the treatment of traumatic brain injury
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  100. A Retrospective, Multi-Center Cohort Study Evaluating the Severity- Related Effects of Cerebrolysin Treatment on Clinical Outcomes in Traumatic Brain Injury
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