Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Loane, David J., Faden, Alan I.·2010·Trends in Pharmacological Sciences

Cited by (574)

Items 301–400 of 574

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  2. N ‑Adamantyl Phthalimidine: A New Thalidomide-like Drug That Lacks Cereblon Binding and Mitigates Neuronal and Synaptic Loss, Neuroinflammation, and Behavioral Deficits in Traumatic Brain Injury and LPS Challenge
    Shih‐Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Yu Kyung Kim, Inho Hwang, Jung-Eun Gil, Baek‐Soo Han, Yung Hsiao Chiang, Warren R. Selman et al. · 2021 · ACS Pharmacology & Translational Science
  3. The use of antioxidants in the treatment of traumatic brain injury
    Whitney Venegoni, Qiuhua Shen, Amanda R. Thimmesch, Meredith Bell, John B. Hiebert, Janet D. Pierce · 2017 · Journal of Advanced Nursing
  4. RNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury
    Suresh Babu Rangasamy, Supurna Ghosh, Kalipada Pahan · 2020 · Experimental Neurology
  5. Lipopolysaccharide Pre-conditioning Attenuates Pro-inflammatory Responses and Promotes Cytoprotective Effect in Differentiated PC12 Cell Lines via Pre-activation of Toll-Like Receptor-4 Signaling Pathway Leading to the Inhibition of Caspase-3/Nuclear Factor-κappa B Pathway
    Pushpa Gandi Sangaran, Zaridatul Aini Ibrahim, Zamri Chik, Zahurin Mohamed, Abolhassan Ahmadiani · 2021 · Frontiers in Cellular Neuroscience
  6. Amantadine for Traumatic Brain Injury—Supporting Evidence and Mode of Action
    Andrzej Dekundy, Gerald Pichler, Reda Badry, Astrid Scheschonka, Wojciech Danysz · 2024 · Biomedicines
  7. Redistribution of Monocarboxylate 1 and 4 in Hippocampus and Spatial Memory Impairment Induced by Long-term Ketamine Administration
    Runtao Ding, Yaqing Tan, Ao Du, Gehua Wen, Xinghua Ren, Hui Yao, Weishu Ren, Huairu Liu, Xiaolong Wang, Hao Qiang Yu et al. · 2020 · Frontiers in Behavioral Neuroscience
  8. Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS‐Stimulated BV2 Microglia Cells
    Piao Zheng, Xuefei Tian, Wei Zhang, Zhaoyu Yang, Jing Zhou, Jun Zheng, Hanjin Cui, Tao Tang, Jiekun Luo, Yang Wang · 2020 · Evidence-based Complementary and Alternative Medicine
  9. Neuroprotection strategies in traumatic brain injury: Studying the effectiveness of different clinical approaches
    Barbara Buccilli, Albert Alan, Aljeradat Baha’, Akmal Shahzad, Yasser F. Almealawy, N. Chisvo, Michelle Ennabe, Martin E. Weinand · 2024 · Surgical neurology international
  10. Proteomics: in pursuit of effective traumatic brain injury therapeutics
    Pavel N. Lizhnyak, Andrew K. Ottens · 2015 · Espert Review of Proteomics
  11. Diurnal variation of NMDA receptor expression in the rat cerebral cortex is associated with traumatic brain injury damage
    Francisco Estrada-Rojo, Julio Morales‐Gómez, Elvia Coballase-Urrutía, Marina Martínez-Vargas, Luz Navarro · 2018 · BMC Research Notes
  12. Neuroprotective Effects of CGP3466B on Apoptosis Are Modulated by Protein-L-isoaspartate (D-aspartate) O-methyltransferase/Mst1 Pathways after Traumatic Brain Injury in Rats
    Feng Liang, Ligen Shi, Jingwei Zheng, Sheng Chen, Yangxin Wang, Jianmin Zhang · 2017 · Scientific Reports
  13. Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injury
    Aline Alves Courtes, Débora Farina Gonçalves, Diane Duarte Hartmann, Pâmela Carvalho da Rosa, Gustavo Cassol, Luiz Fernando Freire Royes, Nélson Rodrigues de Carvalho, Félix Alexandre Antunes Soares · 2020 · Brain Research Bulletin
  14. Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR
    Srestha Dasgupta, Laura Ester Montroull, Mansi A. Pandya, Juan Pablo Zanin, Wei Wang, Zhuhao Wu, Wilma Friedman · 2023 · eNeuro
  15. Bench to Bedside of Neural Stem Cell in Traumatic Brain Injury
    Solomon O. Ugoya, Jian Tu · 2012 · Stem Cells International
  16. Clinical Traumatic Brain Injury in the Preclinical Setting
    Justin Berkner, Rebekah Mannix, Jianhua Qiu · 2016 · Methods in molecular biology
  17. Therapeutic potential of vitamin E and its derivatives in traumatic brain injury-associated dementia
    Jan Dobrovolný, M. Smrcka, J. Bienertová-Vašků · 2018 · Neurological Sciences
  18. Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI
    Anelia Kassi, Anil K. Mahavadi, Angélica Clavijo, Daniela Caliz, Stephanie Wing Lee, Aminul Islam Ahmed, Shoji Yokobori, Zhen Hu, Markus S. Spurlock, Joseph M. Wasserman et al. · 2019 · Frontiers in Neurology
  19. Fast-tracking regenerative medicine for traumatic brain injury
    Brooke Bonsack, Matt Heyck, Chase Kingsbury, Blaise Cozene, Nadia Sadanandan, Jea-Young Lee, Cesar V. Borlongan · 2020 · Neural Regeneration Research
  20. Pharmacokinetic Analysis of Peptide-Modified Nanoparticles with Engineered Physicochemical Properties in a Mouse Model of Traumatic Brain Injury
    Lauren E. Waggoner, Marianne I. Madias, Alan A. Hurtado, Ester J. Kwon · 2021 · The AAPS Journal
  21. RETRACTED: Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury
    Suresh Babu Rangasamy, Sumita Raha, Sridevi Dasarathi, Kalipada Pahan · 2021 · International Journal of Molecular Sciences · Retracted
  22. A bilateral head injury that shows graded brain damage and behavioral deficits in adultmice
    Nai‐Kui Liu, Yi-Ping Zhang, Jeremy M. O’Connor, Alexander Gianaris, Eddie Oakes, Qingbo Lu, Tom Verhovshek, Chandler L. Walker, Christopher B. Shields, Xiao‐Ming Xu · 2012 · Brain Research
  23. Therapeutic Prospective of Infused Allogenic Cultured Mesenchymal Stem Cells in Traumatic Brain Injury Mice: A Longitudinal Proton Magnetic Resonance Spectroscopy Assessment
    Sushanta Kumar Mishra, Poonam Rana, Subash Khushu, Gurudutta U. Gangenahalli · 2016 · Stem Cells Translational Medicine
  24. Hsp70 inducer, 17-allylamino-demethoxygeldanamycin, provides neuroprotection via anti-inflammatory effects in a rat model of traumatic brain injury
    Youquan Gu, Jun Chen, Tianhong Wang, Chaoning Zhou, Zhaodong Liu, Lanhua Ma · 2016 · Experimental and Therapeutic Medicine · Retracted
  25. Post‐injury administration of a combination of memantine and 17&bgr;‐estradiol is protective in a rat model of traumatic brain injury
    Nicole L. Day, Matthew S. Carle, Candace L. Floyd · 2017 · Neurochemistry International
  26. A semicircular controlled cortical impact produces long-term motor and cognitive dysfunction that correlates well with damage to both the sensorimotor cortex and hippocampus
    Nai‐Kui Liu, Yi-Ping Zhang, Jian Zou, Tom Verhovshek, Chen Chen, Qingbo Lu, Chandler L. Walker, Christopher B. Shields, Xiao‐Ming Xu · 2014 · Brain Research
  27. Small Molecules: Therapeutic Application in Neuropsychiatric and Neurodegenerative Disorders
    Stefania Schiavone, Luigia Trabace · 2018 · Molecules
  28. Design and In Vitro Study of a Dual Drug-Loaded Delivery System Produced by Electrospinning for the Treatment of Acute Injuries of the Central Nervous System
    Luisa Stella Dolci, Rosaria Carmela Perone, Roberto Di Gesù, Mallesh Kurakula, Chiara Gualandi, Elisa Zironi, Teresa Gazzotti, Maria Teresa Tondo, Giampiero Pagliuca, Natalia Gostyńska et al. · 2021 · Pharmaceutics
  29. Genome-wide interrogation of transfer RNA-derived small RNAs in a mouse model of traumatic brain injury
    Xiao-Jian Xu, Meng-Shi Yang, Bin Zhang, Qianqian Ge, Fei Niu, Jinqian Dong, Yuan Zhuang, Bai-Yun Liu · 2021 · Neural Regeneration Research
  30. A Study on the Mechanism by Which MDMA Protects Against Dopaminergic Dysfunction After Minimal Traumatic Brain Injury (mTBI) in Mice
    Shahaf Edut, Vardit Rubovitch, Moshe Rehavi, Shaul Schreiber, Chaim G. Pick · 2014 · Journal of Molecular Neuroscience
  31. Bilateral gene interaction hierarchy analysis of the cell death gene response emphasizes the significance of cell cycle genes following unilateral traumatic brain injury
    Todd E. White, Monique C. Surles-Zeigler, Gregory D. Ford, Alicia Gates, Benem Davids, Timothy J. Distel, Michelle C. LaPlaca, Byron D. Ford · 2016 · BMC Genomics
  32. Acute histopathological responses and long-term behavioral outcomes in mice with graded controlled cortical impact injury
    Si-Yi Xu, Min Liu, Yang Gao, Yang Cao, Yang Cao, Yingying Lin, Yong Wang, Qizhong Luo, Jiyao Jiang, Chun-Long Zhong · 2019 · Neural Regeneration Research
  33. The role of brain barriers in the neurokinetics and pharmacodynamics of lithium
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  34. The Effectiveness of Trigeminal Nerve Stimulation on Traumatic Brain Injury
    Qian Yang, Subo Zhang, Zhen Xu, Lijiaqi Liu, Shengnuo Fan, Shaoling Wu, Chao Ma · 2022 · Neuromodulation Technology at the Neural Interface
  35. Chronically dysregulated NOTCH1 interactome in the dentate gyrus after traumatic brain injury
    Noora Puhakka, Anna Maria Bot, Niina Vuokila, Konrad Józef Dębski, Katarzyna Łukasiuk, Asla Pitkänen · 2017 · PLoS ONE
  36. Role of autonomic system imbalance in neurogenic pulmonary oedema
    Aobing Yang, Bin Liu, Tsuyoshi Inoue · 2022 · European Journal of Neuroscience
  37. An overview on microglial origin, distribution, and phenotype in Alzheimer's disease
    Rezwanul Islam, Hadi Hasan Choudhary, Robin G. Rajan, Frank D. Vrionis, Khalid A. Hanafy · 2022 · Journal of Cellular Physiology
  38. Enhanced Targeted Delivery of Minocycline via Transferrin Conjugated Albumin Nanoparticle Improves Neuroprotection in a Blast Traumatic Brain Injury Model
    Venkatesan Perumal, Arun Reddy Ravula, Agnieszka Agas, Aakaash Gosain, Aswati Aravind, Ponnurengam Malliappan Sivakumar, Shanmuga Sundari, Karthik Sambath, Sivakumar Vijayaraghavalu, Namas Chandra · 2023 · Brain Sciences
  39. Temporal assessment of traumatic axonal injury in the rat corpus callosum and optic chiasm
    Nisrine Zakaria, Srinivasu Kallakuri, Sharath Bandaru, John M. Cavanaugh · 2012 · Brain Research
  40. Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus
    Yushan Wang, Thomas W. Sawyer, Yiu Chung Tse, Changyang Fan, Grant Hennes, Julia Barnes, Tyson Josey, Tracy Weiss, Peggy Nelson, Tak Pan Wong · 2017 · Frontiers in Neurology
  41. Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury
    Viraj Pandit, Muhammad Khan, E. Zakaria, T. Largent-Milnes, M. Hamidi, T. Okeeffe, T. Vanderah, B. Joseph · 2018 · Journal of Trauma and Acute Care Surgery
  42. tec-1 kinase negatively regulates regenerative neurogenesis in planarians
    Alexander Karge, Nicolle A. Bonar, Scott Wood, Christian P. Petersen · 2020 · eLife
  43. Visualization of cortical cerebral blood flow dynamics during craniotomy in acute subdural hematoma using laser speckle imaging in a rat model
    Cheng Wang, Liang Xian, Xiangrong Chen, Zuanfang Li, Yi Fang, Weiming Xu, Liangfeng Wei, Weiqiang Chen, Shousen Wang · 2020 · Brain Research
  44. In-Hospital Mortality Following Traumatic Brain Injury Among Older Medicare Beneficiaries, Comparing Statin Users With Nonusers
    Bilal Khokhar, Jane M. Simoni, Julia F. Slejko, Eleanor M. Perfetto, Min Zhan, Gordon Stephen Smith · 2017 · Journal of Pharmacy Technology
  45. Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Erwin Kristobal Gudenschwager Basso, Jing Ju, Eman Soliman, Caroline de Jager, Xiaoran Wei, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Journal of Neuroinflammation
  46. Gambogic amide, a selective TrkA agonist, does not improve outcomes from traumatic brain injury in mice
    Maddison R Johnstone, Mujun Sun, Caroline J. Taylor, Rhys D. Brady, Brian L. Grills, Jarrod E. Church, Sandy R. Shultz, Stuart J. McDonald · 2017 · Brain Injury
  47. Effect of Implementing the Out-of-Hospital Traumatic Brain Injury Treatment Guidelines: The Excellence in Prehospital Injury Care for Children Study (EPIC4Kids)
    Joshua B. Gaither, Daniel W. Spaite, Bentley J. Bobrow, Samuel M. Keim, Bruce J. Barnhart, Vatsal Chikani, Duane L. Sherrill, Kurt R. Denninghoff, Terry Mullins, P. David Adelson et al. · 2020 · Annals of Emergency Medicine
  48. Facilitated Assessment of Tissue Loss Following Traumatic Brain Injury
    Anders Hånell, Johanna Hedin, Fredrik Clausen, Niklas Marklund · 2012 · Frontiers in Neurology
  49. Recent Advances and Future Trends in Traumatic Brain Injury
    Syed Amin Tabish, N. Syed · 2015 · Emergency Medicine Open Access
  50. Neuroimaging of brain trauma
    David Douglas, Jonathan Muldermans, Max Wintermark · 2018 · Current Opinion in Neurology
  51. Current State of Diffusion-Weighted Imaging and Diffusion Tensor Imaging for Traumatic Brain Injury Prognostication
    Matthew Grant, JiaJing Liu, Max Wintermark, Ulaş Bağcı, David Douglas · 2023 · Neuroimaging Clinics of North America
  52. Acute Kahweol Treatment Attenuates Traumatic Brain Injury Neuroinflammation and Functional Deficits
    Hung‐Fu Lee, Jhih Syuan Lin, Che-Feng Chang · 2019 · Nutrients
  53. REMOVED: Concussive head injury exacerbates neuropathology of sleep deprivation: Superior neuroprotection by co-administration of TiO2-nanowired cerebrolysin, alpha-melanocyte-stimulating hormone, and mesenchymal stem cells
    Aruna Sharma, Dafin Fior Muresanu, Seaab Sahib, Z. Ryan Tian, Ala Nozari, José Vicente Lafuente, Anca Dana Buzoianu, Igor Bryukhovetskiy, Igor Manzhulo, Ranjana Patnaik et al. · 2020 · Progress in brain research
  54. Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway
    Huan Liu, Shiqing He, Chong V. Li, Jianpeng Wang, Qin Zou, Yongshi Liao, Rui Chen · 2022 · Brain and Behavior
  55. Induced neural stem cell-derived astrocytes modulate complement activation and mediate neuroprotection following closed head injury
    Mou Gao, Qin Dong, Yingzhou Lu, Hui Yao, Mingming Zou, Yang Yang, Jianwei Zhu, Zhijun Yang, Minhui Xu, Ruxiang Xu · 2018 · Cell Death and Disease
  56. Research Progress on the Inflammatory Effects of Long Non-coding RNA in Traumatic Brain Injury
    Jianpeng Wang, Chong Li, Wencong Ding, Gang Peng, Gelei Xiao, Rui Chen, Quan Cheng · 2022 · Frontiers in Molecular Neuroscience
  57. Recent advances in photobiomodulation therapy for brain diseases
    Sihan Dong, Hang Ren, Rui Zhang, Xunbin Wei · 2024 · Interdisciplinary medicine
  58. The importance of behavioral interventions in traumatic brain injury
    Barbara Buccilli, Albert Alan, Baha’ Aljeradat, Akmal Shahzad, Yasser F. Almealawy, Nathan Simbarashe Chisvo, Michelle Ennabe, Martin E. Weinand · 2024 · Surgical Neurology International
  59. Metabolic-driven analytics of traumatic brain injury and neuroprotection by ethyl pyruvate
    Nikita Golovachev, Lorraine Siebold, Richard L. Sutton, Sima S. Ghavim, Neil G. Harris, Brenda Bartnik‐Olson · 2024 · Journal of Neuroinflammation
  60. Inhibition of cytoskeletal protein carbonylation may protect against oxidative damage in traumatic brain injury
    Qiusheng Zhang, Meng Zhang, Xianjian Huang, Xiaojia Liu, Weiping Li · 2016 · Experimental and Therapeutic Medicine
  61. Impact of 5-lipoxygenase inhibitors on the spatiotemporal distribution of inflammatory cells and neuronal COX-2 expression following experimental traumatic brain injury in rats
    Wolfgang Härtig, Dominik Michalski, Gudrun Seeger, Cornelia Voigt, Cornelius Kurt Donat, Julia Dulin, Johannes Kacza, Jürgen Meixensberger, Thomas Arendt, Martin U. Schuhmann · 2012 · Brain Research
  62. Prospective, randomized, blinded, and placebo-controlled study of Cerebrolysin dose-response effects on long-term functional outcomes in a rat model of mild traumatic brain injury.
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  63. Increasing Rigor of Preclinical Research to Maximize Opportunities for Translation
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  64. Can transcranial photobiomodulation improve cognitive function in TBI patients? A systematic review
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  65. PEGylated Multimeric RNA Nanoparticles for siRNA Delivery in Traumatic Brain Injury
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  66. Neuroinflammatory Response in the Traumatic Brain Injury: An Update
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  67. Lrg Participates in Lipopolysaccharide Preconditioning-Induced Brain Ischemia Injury via TLR4 Signaling Pathway
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  68. GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice
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  69. DCC/netrin-1 regulates cell death in oligodendrocytes after brain injury
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  70. Proneurotrophins Induce Apoptotic Neuronal Death After Controlled Cortical Impact Injury in Adult Mice
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  71. Neuroprotection: Surgical approaches in traumatic brain injury
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  72. Licoricidin improves neurological dysfunction after traumatic brain injury in mice via regulating FoxO3/Wnt/β-catenin pathway
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  73. Pectic Galactan Polysaccharide‐Based Gene Delivery System for Targeting Neuroinflammation
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  74. Role of TGF-β Signaling in Neurogenic Regions After Brain Injury
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  75. Dual-wavelength laser speckle imaging for monitoring brain metabolic and hemodynamic response to closed head traumatic brain injury in mice
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  76. Models of Posttraumatic Brain Injury Neurorehabilitation
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  77. Delayed metformin treatment improves functional recovery following traumatic brain injury via central AMPK-dependent brain tissue repair
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  78. Increased expression of AGS3 in rat brain cortex after traumatic brain injury
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  79. MicroRNA-31 inhibits traumatic brain injury-triggered neuronal cell apoptosis by regulating hypoxia-inducible factor-1A/vascular endothelial growth factor A axis
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  80. Chronic Traumatic Encephalopathy as the Course of Alzheimer’s Disease
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  81. Up-regulation of MCM3 Relates to Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats
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  82. Interactions of Glutamate and Gamma Amino Butyric Acid with the insulin-like growth factor system in traumatic brain injury (TBI) and/or cardiovascular accidents (CVA or stroke): A systematic review
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  83. Neuroprotection in Traumatic Brain Injury
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  84. Improvement in cognitive dysfunction following blast induced traumatic brain injury by thymosin α1 in rats: Involvement of inhibition of tau phosphorylation at the Thr205 epitope
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  85. Evidence for Altered White Matter Organization After Mild Traumatic Brain Injury: A Scoping Review on the Use of Diffusion Magnetic Resonance Imaging and Blood-Based Biomarkers to Investigate Acute Pathology and Relationship to Persistent Post-Concussion Symptoms
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  89. The role of bioactive lipids in attenuating the neuroinflammatory cascade in traumatic brain injury
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  90. Boswellia serrata extract shows cognitive benefits in a double-blind, randomized, placebo-controlled pilot clinical trial in individuals who suffered traumatic brain injury
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  93. Transgenic over-expression of slit2 enhances disruption of blood-brain barrier and increases cell death after traumatic brain injury in mice
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  94. Risk factors for intracranial lesions and mortality in older patients with mild traumatic brain injuries
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  95. Chapter 5 – Traumatic Brain Injury
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  100. Membrane transporters in traumatic brain injury: Pathological, pharmacotherapeutic, and developmental implications
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