Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Loane, David J., Faden, Alan I.·2010·Trends in Pharmacological Sciences

Cited by (574)

Items 501–574 of 574

  1. Transcranial low-level laser therapy increases memory, learning, neuroprogenitor cells, BDNF and synaptogenesis in mice with traumatic brain injury
    Weijun Xuan, Liyi Huang, Fatma Vatansever, Tanupriya Agrawal, Michael Richard Hamblin · 2015 · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
  2. Study the efficacy of neuroprotective drugs on brain physiological properties during focal head injury using optical spectroscopy data analysis
    David Abookasis, Ariel Shochat · 2016 · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE
  3. Targeting acute phosphatase PTEN inhibition and investigation of a novel combination treatment with Schwann cell transplantation to promote spinal cord injury repair in rats
    Chandler L. Walker · 2014 · IUScholarWorks (Indiana University)
  4. Is the animal brain the same as the human brain?*
    Javed Akhtar · 2012 · Critical Care Medicine
  5. Activity of the astrocytes' adenosine signaling system components in model of traumatic brain injury in vivo and in vitro
    Ana Parabucki · 2013
  6. Photochemical Strategies to Decage Organic Compounds
    Clinton J. Regan · 2016 · CaltechTHESIS (California Institute of Technology)
  7. Vascular Responses in Rodent Models of Traumatic Brain Injury
    Xiaoshu Wang, Zhanyang Yu, 廖正步, Qi Liu, MingMing Ning, Xiaochuan Sun, Josephine Lok, Eng H. Lo, Xiaoying Wang · 2013 · Springer eBooks
  8. Low-Level Laser (Light) Therapy for Rehabilitation in Traumatic Brain Injury and Stroke, including Chronic Aphasia
    Margaret A. Naeser, Paula I. Martin, Michael D. Ho, Maxine Krengel, Yelena Bogdanova, Jeffrey Knight, Megan K. Yee, ROSS D. ZAFONTE, Bang‐Bon Koo, John G. Roubil et al. · 2016
  9. Physical Activity
    Rainer Beurskens, Marc Dalecki · 2017 · Elsevier eBooks
  10. Translational obstacles with off-label drug use in acute traumatic brain injury
    S. Mirzaei, A. Reinig, D. Berlau · 2017 · Future Neurology
  11. The effect of post-injury erythropoietin administration on mortality and Glasgow outcome scales of patients with traumatic brain injury: A metaanalysis.
    Faye B Garciano, Perry N Noble · 2017
  12. Neuroprotection of hyperbaric oxygen treatment for traumatic brain injury involving autophagy pathway in rats
    Wenchao Liu, Liang Wen, Hao Wang, Jiangbiao Gong, TianXiang Zhan, Yuanyuan Meng, Xiaofeng Yang · 2017 · Journal of Neurorestoratology
  13. Blood-Brain Barrier Dysfunction and Repair after Blast-Induced Traumatic Brain Injury
    Christopher D. Hue · 2015
  14. Difficulties in Clinical Trials to Treat Traumatic Brain Injury and Stroke
    Alfonso Lagares, María de Toledo · 2017 · Royal Society of Chemistry eBooks
  15. Editorial: Monitoring Pathophysiology in the Injured Brain
    Eric Peter Thelin, Adel E Helmy, David Nelson, Niklas Marklund · 2018 · Frontiers in Neurology
  16. THE ROLE OF MEMBRANE TRANSPORTERS IN TRAUMATIC BRAIN INJURY: INTERVENTIONAL AND GENETIC INVESTIGATIONS
    Fanuel T. Hagos · 2018 · D-Scholarship@Pitt (University of Pittsburgh)
  17. Gene Therapy for Neuroanesthesia
    Ellen S. Hauck, James G. Hecker · 2019 · Springer eBooks
  18. Interleukin 33 Initiates CNS Inflammation Following Traumatic Injury
    Sachin P. Gadani · 2016
  19. Temporal and spatial effects of shock overpressure on blood-brain barrier permeability in blast-induced traumatic brain injury
    Matthew Kuriakose · 2018
  20. Neuroprotection by noble gases in models of brain injury
    Mariia Koziakova · 2017 · Spiral (Imperial College London)
  21. Introduction to the Special Issue on Translation
    Douglas S. DeWitt, Donald S. Prough · 2020 · Journal of Neurotrauma
  22. CHARACTERIZATION AND TARGETING OF THE ENDOCANNABINOID SYSTEM IN TRAUMATIC BRAIN INJURY
    Tallan Black · 2020 · HARVEST (University of Saskatchewan)
  23. Minocycline as a treatment for traumatic brain injury-induced impulsive and attentional deficits
    Kristen M Pechacek · 2020
  24. Angiotensin II Receptor Type 2 Activation Does Not Influence Brain Damage, Neurological Impairment and Inflammation After Experimental Traumatic Brain Injury
    Ralph Timaru‐Kast, Andreas García-Bardon, Clara Luh, Shila P. Coronel-Castello, Phuriphong Songarj, Eva‐Verena Griemert, Tobias J. Krämer, Anne Sebastiani, U. Muscha Steckelings, Serge Christian Thal · 2021 · Research Square
  25. Selective activation of cannabinoid receptor-2 reduces white matter injury via PERK signaling in a rat model of traumatic brain injury
    Li Jiang, Lin Li, Qingqing Luo, Bin Shang, Xiaomin Yang, Jiru Zhou, Qiuling Pan, Na Wu, Wei Tang, Donglin Du et al. · 2021 · Research Square
  26. Chapter 39 Low-Level Laser (Light) Therapy for Rehabilitation in Traumatic Brain Injury and Stroke, including Chronic Aphasia
    Margaret A. Naeser, Paula I. Martin, Michael D. Ho, Maxine Krengel, Yelena Bogdanova, Jeffrey Knight, Megan K. Yee, ROSS D. ZAFONTE, Bang‐Bon Koo, John G. Roubil et al. · 2016 · Pan Stanford Publishing Pte. Ltd. eBooks
  27. Selective Activation of Cannabinoid Receptor-2 Reduces White Matter Injury via Perk Signaling in a Rat Model of Traumatic Brain Injury
    li jiang, Lin Li, Qingqing Luo, Bin Shang, Xiaomin Yang, Jiru Zhou, Qiuling Pan, Na Wu, Wei Tang, Xiaochuan Sun et al. · 2021 · Research Square
  28. Pharmacologic Neuroprotection
    Nino Stocchetti, Marco Carbonara · 2017 · Oxford University Press eBooks
  29. Neurotrauma, Emerging Research
    Katarzyna H. Czerniecka, Anthony L. Petraglia · 2015 · Springer eBooks
  30. Neuroprotective agents in critical illness
    Jerrold L. Perrott, Steven Reynolds · 2016
  31. Testosterone: Features and role in treating traumatic brain injury
    Nathan Ryzewski Strogulski, Randhall Bruce Carteri, Eduardo Kalinine, Luis Valmor Portela · 2022 · Elsevier eBooks
  32. Role of endocannabinoids in the escalation of alcohol use following traumatic brain injury
    Patricia E. Molina, Zachary F. Stielper, Scott Edwards, Nicholas W. Gilpin · 2022 · Elsevier eBooks
  33. Hearing Damage Through Blast
    Tobias Reichenbach · 2022 · Springer eBooks
  34. Developing an Ovine Model of Impact Traumatic Brain Injury
    C. C. Magarey, R. Quarrington, C. F. Jones · 2023 · SAE International Journal of Transportation Safety
  35. Use of pulsed high intensity focused ultrasound to study the response of brain endothelial cells to mechanical injury
    Rajwinder Kaur · 2023
  36. Use of pulsed high intensity focused ultrasound to study the response of brain endothelial cells to mechanical injury
    Rajwinder Kaur · 2023
  37. Ferroptosis in Central Nervous System Hypoxia–Ischemia
    Namood-e Sahar, Eric S. Peeples · 2023 · Springer eBooks
  38. Brain Injury Knowledge Ontology (BIKO) for traumatic brain injury: Formalizing concepts and methods used in translational traumatic brain injury research
    M. Surles-Zeigler, Troy Sincomb, C. Dixon, Fahim T. Imam, Tom Gillespie, J. Grethe, A. Ferguson, Maryann E. Martone · 2023 · bioRxiv
  39. Signaling pathway and pharmacology
    Xiaokun Li · 2024 · Elsevier eBooks
  40. Investigation of Diffuse Axonal Injury in Rats Induced by the Combined Linear and Rotational Accelerations Using Diffusion Tensor Imaging
    Peng Wang, Xuewei Song, Diyou Chen, Xiyan Zhu, Jinlong Qiu, Nan Wang, Tianming Yu, Hui Zhao · 2024 · SAE technical papers on CD-ROM/SAE technical paper series
  41. Engineered Tools to Advance Cell Transplantation in the Nervous System Towards a Clinical Reality
    Isabella G Cozzone, Victoria L. Ortega, Courtney M. Dumont · 2024 · Current Transplantation Reports
  42. Applications and Recent Advances of Nanotechnology and Nanomedicine in the Diagnosis and Therapy of Stroke
    Mehrnaz Gholami, Kevin Morris, Ana Maria Torres, Taha Tsouli Kamal, Behnam Rezai Jahromi, Abilash Haridas, Babak Kateb · 2024 · Springer eBooks
  43. Polyunsaturated Fatty Acids and Traumatic Brain Injury
    Kholoud Elsamman · 2024 · Nutritional neurosciences
  44. Nanoimaging in Neurology
    Sikandar Shaikh · 2024 · Springer eBooks
  45. Genetic Modifiers Influencing the Acute and Long-Term Responses to Traumatic Brain Injury in Drosophila
    Brandon Molina, Jesse Jacob Rojas, Nadja El-Mecharrafie, Eric P. Ratliff, Marta M. Lipinski, Kim D. Finley · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  46. Applied Neuropathophysiology and Neuropharmacology
    Kelley Flesher, William Andrew Kofke, Ramani Balu · 2025
  47. Quantum dots for the treatment of neurodegenerative disorders
    Srinivasan Girija, Jeyaraj Wilson, Periyasamy Ananthappan, Vairathevar Sivasamy Vasantha · 2025 · Elsevier eBooks
  48. NEUROINFLAMMATION IN ACUTE TRAUMATIC BRAIN INJURY
    Vlad Liviu Hartie, Maria Victoria Comanescu, Emilia Pătrășcanu, Andrei Ionuț Cucu, Lidia Cureniuc, Otilia Boișteanu, Mihaela Dana Turliuc · 2025 · Romanian Journal of Oral Rehabilitation
  49. Additional file 2 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  50. Additional file 5 of Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Gudenschwager Basso, Erwin K., Jing Ju, Eman Soliman, Caroline de Jager, Wei, Xiaoran, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Figshare
  51. Additional file 3 of Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Gudenschwager Basso, Erwin K., Jing Ju, Eman Soliman, Caroline de Jager, Wei, Xiaoran, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Figshare
  52. Additional file 5 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  53. Additional file 1 of GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice
    Chen, Huazhen, Karl Kevala, Elma Aflaki, Marugan, Juan, Kim, Hee-Yong · 2021 · Figshare
  54. Additional file 2 of Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Gudenschwager Basso, Erwin K., Jing Ju, Eman Soliman, Caroline de Jager, Wei, Xiaoran, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Figshare
  55. Additional file 1 of Germacrone alleviates neurological deficits following traumatic brain injury by modulating neuroinflammation and oxidative stress
    Zhuang, Sujing, Liu, Baogui, Guo, Shifeng, Yanzhong Xue, Wu, Lin, Liu, Shiqi, Zhang, Chunling, Ni, Xiuyan · 2021 · Figshare
  56. Additional file 6 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  57. Additional file 4 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  58. Additional file 1 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  59. Additional file 3 of Mer regulates microglial/macrophage M1/M2 polarization and alleviates neuroinflammation following traumatic brain injury
    Wu, Haijian, Zheng, Jingwei, Shenbin Xu, Fang, Yuanjian, Wu, Yingxi, Jianxiong Zeng, Shao, Anwen, Shi, Ligen, Jianan Lü, Mei, Shuhao et al. · 2021 · Figshare
  60. Additional file 1 of Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Gudenschwager Basso, Erwin K., Jing Ju, Eman Soliman, Caroline de Jager, Wei, Xiaoran, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Figshare
  61. Additional file 4 of Immunoregulatory and neutrophil-like monocyte subsets with distinct single-cell transcriptomic signatures emerge following brain injury
    Gudenschwager Basso, Erwin K., Jing Ju, Eman Soliman, Caroline de Jager, Wei, Xiaoran, Kevin J. Pridham, Michelle Lynne Olsen, Michelle Hedrick Theus · 2024 · Figshare
  62. Heterogeneity of acute traumatic brain injured patients: how to identify phenotypes and tailor specific treatment
    Katerina Negri, Marianna Di Feliciantonio, Tommaso Zoerle · 2026 · Current Opinion in Critical Care
  63. Photobiomodulation for traumatic brain injury
    Michael Richard Hamblin · 2026 · International review of neurobiology
  64. Topiramate protects against neuroinflammation in response to traumatic brain injury via activating Sirt1 signaling
    Xu Zhang, Ao Li, Ying Zhang, Wen-Kai Wu, Zhizhong Yan, Tao Chen, Yu-Hai Wang · 2026 · Scientific Reports
  65. Mapping Inflammation Dynamics Across Brain, CSF, and Serum after TBI: A Multi-Compartment and Machine Learning Analysis of Injury and Celastrol Effects
    Brock J. Gjesdal, Sohan Rao, Ektha Parchuri, Zachary Rohde, Jeremy J. Henchir, Youming Li, Yue-Fang Chang, Shaun W Carlson, C. E. Dixon · 2026 · Neurotrauma Reports
  66. Attenuation of Reactive Astrogliosis Accompanies Neurological Recovery Induced by Novel Poly-Target 2,3-Benzodiazepines After Experimental Traumatic Brain Injury
    Sergiy V. Ziablitsev, Nadia O. Aleksandrenko, Danylo I Yevstifeiev, Mai Babenko, Volodymyr V. Likhodiievskyi · 2026 · Research Square
  67. Silybin attenuates neurobehavioural impairments and secondary brain damage following traumatic brain injury in mice
    Hemlata Bhardwaj, Sunil Sharma, Neeru Vasudeva · 2026 · Scripta Medica
  68. Multi-omics integration reveals TIM-4 as a master regulatory hub of neuroinflammation and neuronal cell death
    Liang Chen, Yan‐Yan Li, Li Han, Shiqi Lu · 2026 · Frontiers in Cell and Developmental Biology
  69. Mechanism-Targeted Therapeutic Strategies for Traumatic Brain Injury: From Molecular Pathways to Functional Recovery
    Ana Costa, Steven Davidson, Emiliya Rakhamimova, Benjamin Bartula, Sofia Geralemou, Weidong Wang, Sergio Daniel Bergese · 2026 · Frontiers in Bioscience-Landmark
  70. Translational Inefficiencies in Traumatic Brain Injury Research: Evidence From 94 399 Publications.
    Daniel N. de Souza, S. Frome, Eric A. Grin, Scott N. Grossman, Paul P. Huang, D. Kurland · 2026 · Neurosurgery
  71. AMPA Receptor Antagonists in Preclinical Models of Traumatic Brain Injury: A Systematic Review and Meta-analysis of Animal Studies.
    Sylvain Gourier, Caroline Morin, T. Gargadennec, A. Turgeon, C. Poulain, Antoine Roquilly, Anaïs Caillard, Olivier Langeron, Marwan Bouras · 2026 · Neurocritical Care
  72. Deletion of NLRP3 gene blocks traumatic brain injury induced abnormal immune response in mice with a genetic background for AD
    Jakob C Green, Zheng Liu, Sarah Timis, Christopher Nelson, Alexandra Pedin, Chunqing Guo, Xiang-Yang Wang, Shijun Zhang, Dong Sun · 2026 · Experimental Neurology
  73. Targeting Neuroinflammation After Traumatic Brain Injury: Addressing Sex Differences to Improve Clinical Translation
    Caitlin Anne Sharratt, Jessica Leigh Hall, Peter John Crack, Hui X. Tan · 2026 · Pharmaceuticals
  74. Omics-guided therapeutic translation in acute traumatic brain injury
    Logan R. Van Nynatten, Enis Cela, Aleah Wilson, Ian Michael Ball, Douglas D. Fraser · 2026 · Frontiers in Pharmacology