Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies
Loane, David J., Faden, Alan I.·2010·Trends in Pharmacological Sciences
Cited by (574)
Items 201–300 of 574
- Long non-coding RNA Gm4419 promotes trauma-induced astrocyte apoptosis by targeting tumor necrosis factor αYunhu Yu, Fang Cao, Qishan Ran, Fei Wang · 2017 · Biochemical and Biophysical Research Communications
- Brain Phospholipid Precursors Administered Post-Injury Reduce Tissue Damage and Improve Neurological Outcome in Experimental Traumatic Brain InjuryOrli Thau‐Zuchman, Rita N. Gomes, Simon C. Dyall, Meirion Davies, John V. Priestley, Martine Groenendijk, Martijn C. de Wilde, Jordi L. Tremoleda, Adina Teodora Michael-Titus · 2018 · Journal of Neurotrauma
- RETRACTED: Therapeutic effects of chrysin in a rat model of traumatic brain injury: A behavioral, biochemical, and histological studyMasome Rashno, Alireza Sarkaki, Yaghoob Farbood, Mohammad Menati Rashno, Layasadat Khorsandi, Mohammad Kazem Gharib Naseri, Mahin Dianat · 2019 · Life Sciences · Retracted
- FGF20 Protected Against BBB Disruption After Traumatic Brain Injury by Upregulating Junction Protein Expression and Inhibiting the Inflammatory ResponseJun Chen, Xue Wang, JIAN LI HU, Jingting Du, Confidence Dordoe, Qiulin Zhou, Wenting Huang, Ruili Guo, Fanyi Han, Kaiming Guo et al. · 2021 · Frontiers in Pharmacology
- Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12Cole Vonder Haar, Kris M. Martens, Lara‐Kirstie Riparip, Susanna Rosi, Cheryl Lea Wellington, Catharine A. Winstanley · 2017 · Journal of Neurotrauma
- Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory ModulationShuxuan Huang, Guozhen Qiu, Fu-Rong Cheng, Zhong Pei, Zhi Yang, Xuhui Deng, Jinhua Zhu, Lue Chen, Chun-Chun Chen, Weifeng Lin et al. · 2018 · Neurochemical Research
- Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in MiceMehmet Yalçın Günal, Ayşe Arzu ŞAKUL, Ahmet Burak Caglayan, Füsun Erten, Öznur Ece Durmaz Kurşun, Ertuğrul Kılıç, Kazım Şahin · 2021 · Neurotoxicity Research
- Azilsartan, an angiotensin II type 1 receptor blocker, attenuates tert-butyl hydroperoxide-induced endothelial cell injury through inhibition of mitochondrial dysfunction and anti-inflammatory activityHao Liu, Ping Mao, Jia Wang, Tuo Wang, Chang-Hou Xie · 2016 · Neurochemistry International
- Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood–brain barrier after traumatic brain injury in miceX. Tao, Xianfei Chen, Shuyu Hao, Z. Hou, T. Lu, Ming Sun, B. Liu · 2015 · Neuroscience
- Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditionsHye-Min Sohn, Jin‐Young Hwang, Jung‐Hee Ryu, Jinhee Kim, Seong-Joo Park, Jin-woo Park, Sung‐Hee Han · 2017 · Journal of Orthopaedic Surgery and Research
- Perioperative Management of Severe Traumatic Brain Injury: What Is New?Deacon Farrell, Audrée A. Bendo · 2018 · Current anesthesiology reports
- Exploring Pharmacological Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Traumatic Brain Injury via a Network Pharmacology ApproachYuanyuan Zhong, Jiekun Luo, Tao Tang, Pengfei Li, Tao Liu, Hanjin Cui, Yang Wang, Zebing Huang · 2018 · Evidence-based Complementary and Alternative Medicine
- A Systematic Review of ASL Perfusion MRI in Mild TBIYang Wang, Hannah M Bartels, Lindsay D. Nelson · 2020 · Neuropsychology Review
- Administration of all‐transretinoic acid after experimental traumatic brain injury is brain protectiveRegina Hummel, Sebastian Ulbrich, Dominik Appel, Shuailong Li, Tobias Hirnet, Sonja Zander, Wieslawa Bobkiewicz, Christina Gölz, Michael K. E. Schäfer · 2020 · British Journal of Pharmacology
- The role of the microbiota–gut–brain axis in long‐term neurodegenerative processes following traumatic brain injuryLi Shan Chiu, Ryan S. Anderton · 2022 · European Journal of Neuroscience
- Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectivesGiuliani, Daniela, Ottani, Alessandra, Neri, Laura, Zaffe, Davide, Grieco, Paolo, Jochem, Jerzy, Cavallini, Gian Maria, Catania, Anna, Guarini, Salvatore · 2017 · Progress in Neurobiology
- Application of Tauroursodeoxycholic Acid for Treatment of Neurological and Non-neurological Diseases: Is There a Potential for Treating Traumatic Brain Injury?Kyle R. Gronbeck, Cecília M. P. Rodrigues, Javad Mahmoudi, Eric M. Bershad, Geoffrey S.F. Ling, Salam P. Bachour, Afshin A. Divani · 2016 · Neurocritical Care
- Pathway-Focused PCR Array Profiling of Enriched Populations of Laser Capture Microdissected Hippocampal Cells after Traumatic Brain InjuryDeborah R. Boone, Maria‐Adelaide Micci, Isabella G. Taglialatela, Judy L Hellmich, Harris A. Weisz, Min Bi, Donald S. Prough, Douglas S. DeWitt, Helen L. Hellmich · 2015 · PLoS ONE
- Magnetic Resonance Imaging Pilot Study of Intravenous Glyburide in Traumatic Brain InjuryHoward M. Eisenberg, Martha Elizabeth Shenton, Ofer Pasternak, J. Marc Simard, David O. Okonkwo, Christina Aldrich, Feng He, Sonia Jain, Erik G. Hayman · 2019 · Journal of Neurotrauma
- Efficacy and safety of erythropoietin for traumatic brain injuryMotao Liu, Amy J. Wang, Yu Chen, Gexin Zhao, Zhifeng Jiang, Xinbang Wang, Dongliang Shi, Tiansong Zhang, Bomin Sun, Hua He et al. · 2020 · BMC Neurology
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- Functional suppression of Ripk1 blocks the NF-κB signaling pathway and induces neuron autophagy after traumatic brain injuryJun Liu, Zhengkun Zhu, Leibo Wang, Jixiang Du, Biao Zhang, Xuequan Feng, Guobin Zhang · 2020 · Molecular and Cellular Biochemistry
- High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: Proof-of-conceptJoshua W. Gatson, James W. Simpkins, Victor V. Uteshev · 2015 · Brain Research Bulletin
- microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury.Ji Ma, Shaofeng Shui, Xinwei Han, Dong Guo, Tengfei Li, Lei Yan · 2016 · PubMed Central
- Hyperoxia results in increased aerobic metabolism following acute brain injuryArnab Ghosh, David Highton, Christina Kolyva, Ilias Tachtsidis, Clare E. Elwell, Martin Smith · 2016 · Journal of Cerebral Blood Flow & Metabolism
- Autoantibodies in traumatic brain injury and central nervous system traumaMohamad Raad, Eden A. Nohra, Nour Chams, M. Itani, Farid Ramzi Talih, Stefania Mondello, Firas H. Kobeissy · 2014 · Neuroscience
- Efficacy, Dosage, and Duration of Action of Branched Chain Amino Acid Therapy for Traumatic Brain InjuryJaclynn A. Elkind, Miranda M. Lim, Brian N. Johnson, Chris P. Palmer, Brendan J. Putnam, Matthew P. Kirschen, Akiva S. Cohen · 2015 · Frontiers in Neurology
- Melanocortins as potential therapeutic agents in severe hypoxic conditionsDaniela Giuliani, Letteria Minutoli, Alessandra Ottani, Luca Spaccapelo, Alessandra Bitto, Maria Galantucci, Domenica Altavilla, Francesco Squadrito, Salvatore Guarini · 2012 · Frontiers in Neuroendocrinology
- Combination of Temperature-Sensitive Stem Cells and Mild Hypothermia: A New Potential Therapy for Severe Traumatic Brain InjuryYue Tu, Chong Chen, Hongtao Sun, Shixiang Cheng, Xiaozhi Liu, Yang Qu, Xiao-hong Li, Sai Zhang · 2012 · Journal of Neurotrauma
- Pediatric Traumatic Brain Injury and Autism: Elucidating Shared MechanismsRahul Soloman Singh, Ryan Coddington Turner, Linda Nguyen, Kartik Motwani, Michelle Swatek, Brandon Peter Lucke-Wold · 2016 · Behavioural Neurology
- Efficacy of progesterone for moderate to severe traumatic brain injury: a meta-analysis of randomized clinical trialsChao Lin, H. He, Zheng Li, Yinglong Liu, Honglu Chao, Jing Ji, Ning Liu · 2015 · Scientific Reports
- A single dose of PPARγ agonist pioglitazone reduces cortical oxidative damage and microglial reaction following lateral fluid percussion brain injury in ratsKristina Pilipović, Željko Župan, Petra Dolenec, Jasenka Mršić‐Pelčić, Gordana Župan · 2015 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
- What are the progesterone-induced changes of the outcome and the serum markers of injury, oxidant activity and inflammation in diffuse axonal injury patients?B. Mofid, Z. Soltani, M. Khaksari, N. Shahrokhi, N. Nakhaee, S. Karamouzian, M. Ahmadinejad, Masoud Maiel, P. Khazaeli · 2016 · International Immunopharmacology
- Clinical Management in Traumatic Brain InjuryAmy Yan, Andrew P. Torpey, Erin Morrisroe, Wesam Andraous, Ana Costa, Sergio Daniel Bergese · 2024 · Biomedicines
- Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibitionHaiquan Wang, Zhengbu Liao, Xiaochuan Sun, Quanhong Shi, Gang Huo, Yanfeng Xie, Xiaolan Tang, Xinggang Zhi, Zhaohua Tang · 2014 · Neuropharmacology
- Subacute Intranasal Administration of Tissue Plasminogen Activator Promotes Neuroplasticity and Improves Functional Recovery following Traumatic Brain Injury in RatsYuling Meng, Michael Chopp, Yanlu Zhang, Zhongwu Liu, An Aaron, Asim Mahmood, Ye Xiong · 2014 · PLoS ONE
- A Novel Role for the Endocannabinoid System in Ameliorating Motivation for Alcohol Drinking and Negative Behavioral Affect after Traumatic Brain Injury in RatsElizabeth A. Fucich, Jacques P. Mayeux, Mary Adrienne McGinn, Nicholas W. Gilpin, Scott Edwards, Patricia E. Molina · 2019 · Journal of Neurotrauma
- Monitoring Functional Impairment and Recovery after Traumatic Brain Injury in Rats by fMRIJuha‐Pekka Niskanen, Antti M. Airaksinen, Alejandra Sierra, Joanna K. Huttunen, Jari Nissinen, Pasi A. Karjalainen, Asla Pitkänen, Olli H.J. Gröhn · 2012 · Journal of Neurotrauma
- Exploiting blood-based biomarkers to align preclinical models with human traumatic brain injuryIlaria Lisi, Federico Moro, Edoardo Mazzone, Niklas Marklund, Francesca Pischiutta, Firas H. Kobeissy, Xiang Mao, Frances Corrigan, Adel E Helmy, Fatima Ali Nasrallah et al. · 2024 · Brain
- Rapid loading and prolonged release of latanoprost from a silicone hydrogel contact lensRyan R. Horne, Kevin E. Judd, William George Pitt · 2017 · Journal of Drug Delivery Science and Technology
- Expression signatures of long non-coding RNA and mRNA in human traumatic brain injuryYuhai Wang, Likun Yang, Jie Zhu, Jun-Hui Chen, Yu-Hai Wang, Kun Xiong · 2019 · Neural Regeneration Research
- Alantolactone plays neuroprotective roles in traumatic brain injury in rats via anti-inflammatory, anti-oxidative and anti-apoptosis pathways.Xun Wang, Yu‐Long Lan, Jinshan Xing, Xiaoqiang Lan, Litao Wang, Bo Zhang · 2018 · PubMed Central
- (-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse modelYinyin Wu, Jing Cui · 2020 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Treatment With 2-Pentadecyl-2-Oxazoline Restores Mild Traumatic Brain Injury-Induced Sensorial and Neuropsychiatric DysfunctionsSerena Boccella, Monica Iannotta, Claudia Cristiano, Fabio Arturo Iannotti, Fabio Del Bello, Francesca Guida, Carmela Belardo, Rosmara Infantino, Flavia Ricciardi, Mario Giannella et al. · 2020 · Frontiers in Pharmacology
- Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validationYun-Liang Tang, Yunliang Tang, Ling-Yang Zhong, Jian Jiang, Xiao-Yang Dong, Zhen Feng · 2020 · Neural Regeneration Research
- RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in ratsHaibo Ni, Rui Qin, Yitian Xu, Jun Zhu, Fan Gao, Baoqi Dang, Di Li, Rong Gao, Gang Chen · 2018 · Experimental Neurology
- Upregulation of miRNA‐223‐3p ameliorates RIP3‐mediated necroptosis and inflammatory responses via targeting RIP3 after spinal cord injuryYang Wang, Jianhang Jiao, Pengfei Ren, Minfei Wu · 2019 · Journal of Cellular Biochemistry
- Histological Quantitation of Brain Injury Using Whole Slide Imaging: A Pilot Validation Study in MiceZhenzhou Chen, Dmitriy Shin, Shanyan Chen, Mikhail Kovalenko, Orr Hadass, Brittany N. Tomlison, Dmitry Korkin, Chi‐Ren Shyu, Jiankun Cui, Douglas C. Anthony et al. · 2014 · PLoS ONE
- A meta-analysis of efficacy in pre-clinical human stem cell therapies for traumatic brain injuryJanessa Chang, Michael J Phelan, Brian J Cummings · 2015 · Experimental Neurology
- Early preservation of mitochondrial bioenergetics supports both structural and functional recovery after neurotraumaBridgette D. Semple · 2014 · Experimental Neurology
- Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage ResponseLey‐Hian Low, Yuh-Lit Chow, Yijia Li, Choo‐Peng Goh, Ulrich Putz, John Silke, Toru Ouchi, Jason A. Howitt, Seong‐Seng Tan · 2015 · Journal of Biological Chemistry
- Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational researchMichael R. Grovola, Catherine R. von Reyn, David J. Loane, D. Kacy Cullen · 2023 · Journal of Neuroinflammation
- Selective small-molecule inhibitors as chemical tools to define the roles of matrix metalloproteinases in diseaseJayda E. Meisel, Mayland Chang · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Potential of different cells-derived exosomal microRNA cargos for treating spinal cord injuryDayu Pan, Weixiao Liu, Shibo Zhu, Baoyou Fan, Nanxi Yu, Guangzhi Ning, Shiqing Feng · 2021 · Journal of Orthopaedic Translation
- Nuclear trafficking of Pten after brain injury leads to neuron survival not deathChoo‐Peng Goh, Ulrich Putz, Jason A. Howitt, Ley‐Hian Low, Jenny Margaret Gunnersen, Nicole Bye, Maria Cristina Morganti-Kossmann, Seong‐Seng Tan · 2013 · Experimental Neurology
- Acute Cortical Transhemispheric Diaschisis after Unilateral Traumatic Brain InjuryFlorie Le Prieult, Serge Christian Thal, Kristin Engelhard, Barbara Imbrosci, Thomas Mittmann · 2016 · Journal of Neurotrauma
- RETRACTED ARTICLE: Downregulated lncRNA CRNDE contributes to the enhancement of nerve repair after traumatic brain injury in ratsMin Yi, Xingping Dai, Qiuxia Li, Xia Xu, Yanyi Chen, Dongsheng Wang · 2019 · Cell Cycle · Retracted
- Drosophila as a model to explore secondary injury cascades after traumatic brain injuryLori M. Buhlman, Gokul Krishna, T. Bucky Jones, Theresa Currier Thomas · 2021 · Biomedicine & Pharmacotherapy
- The Complexity of the Blood-Brain Barrier and the Concept of Age-Related Brain Targeting: Challenges and Potential of Novel Solid Lipid-Based FormulationsFederica Sommonte, Ilaria Arduino, Giuseppe Francesco Racaniello, Antonio Lopalco, Angela Assunta Lopedota, Nunzio Denora · 2021 · Journal of Pharmaceutical Sciences
- Downregulation of Homer1b/c improves neuronal survival after traumatic neuronal injury.F. Fei, W. Rao, L. Zhang, B.-G. Chen, J. Li, Z. Fei, Z. Chen · 2014 · Neuroscience
- Understanding the Pathophysiology of Traumatic Brain Injury and the Mechanisms of Action of Neuroprotective InterventionsLoi V. Tran · 2014 · Journal of Trauma Nursing
- Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in ratsJiawei Wang, Handong Wang, Zixiang Cong, Xiangsheng Zhang, Xiaoming Zhou, Ding-Ding Zhang · 2012 · Biochemical and Biophysical Research Communications
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- MicroRNA-21 in the Pathogenesis of Traumatic Brain InjuryWei Ji, Jiantong Jiao, Chao Cheng, Junfei Shao · 2018 · Neurochemical Research
- Progesterone Treatment Shows Benefit in Female Rats in a Pediatric Model of Controlled Cortical Impact InjuryRastafa I. Geddes, Bethany L. Peterson, Donald G. Stein, Iqbal Sayeed · 2016 · PLoS ONE
- Glutamate Excitotoxicity: A Key Secondary Injury Mechanism of Traumatic Brain Injury and Spinal Cord InjuryJiamei Hou, Kelena Klippel, Prodip Bose · 2025 · Frontiers in Bioscience-Landmark
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- Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery: Design and MethodsWai Sang Poon, Pieter E. Vos, Dafin Fior Muresanu, Johannes Vester, Klaus Von Wild, V. Hömberg, Ernest Wang, Tatia M.C. Lee, Christian Matula · 2014 · Journal of Neurotrauma
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- Pharmacologic Inhibition of ADAM10 Attenuates Brain Tissue Loss, Axonal Injury and Pro-inflammatory Gene Expression Following Traumatic Brain Injury in MiceDominik Appel, Regina Hummel, Martin E. Weidemeier, Kristina Endres, Christina Gölz, Michael K. E. Schäfer · 2021 · Frontiers in Cell and Developmental Biology
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