Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

Loane, David J., Faden, Alan I.·2010·Trends in Pharmacological Sciences

Cited by (574)

Items 201–300 of 574

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  2. Brain Phospholipid Precursors Administered Post-Injury Reduce Tissue Damage and Improve Neurological Outcome in Experimental Traumatic Brain Injury
    Orli Thau‐Zuchman, Rita N. Gomes, Simon C. Dyall, Meirion Davies, John V. Priestley, Martine Groenendijk, Martijn C. de Wilde, Jordi L. Tremoleda, Adina Teodora Michael-Titus · 2018 · Journal of Neurotrauma
  3. RETRACTED: Therapeutic effects of chrysin in a rat model of traumatic brain injury: A behavioral, biochemical, and histological study
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  4. FGF20 Protected Against BBB Disruption After Traumatic Brain Injury by Upregulating Junction Protein Expression and Inhibiting the Inflammatory Response
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  5. Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12
    Cole Vonder Haar, Kris M. Martens, Lara‐Kirstie Riparip, Susanna Rosi, Cheryl Lea Wellington, Catharine A. Winstanley · 2017 · Journal of Neurotrauma
  6. Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation
    Shuxuan Huang, Guozhen Qiu, Fu-Rong Cheng, Zhong Pei, Zhi Yang, Xuhui Deng, Jinhua Zhu, Lue Chen, Chun-Chun Chen, Weifeng Lin et al. · 2018 · Neurochemical Research
  7. Protective Effect of Lutein/Zeaxanthin Isomers in Traumatic Brain Injury in Mice
    Mehmet Yalçın Günal, Ayşe Arzu ŞAKUL, Ahmet Burak Caglayan, Füsun Erten, Öznur Ece Durmaz Kurşun, Ertuğrul Kılıç, Kazım Şahin · 2021 · Neurotoxicity Research
  8. Azilsartan, an angiotensin II type 1 receptor blocker, attenuates tert-butyl hydroperoxide-induced endothelial cell injury through inhibition of mitochondrial dysfunction and anti-inflammatory activity
    Hao Liu, Ping Mao, Jia Wang, Tuo Wang, Chang-Hou Xie · 2016 · Neurochemistry International
  9. Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood–brain barrier after traumatic brain injury in mice
    X. Tao, Xianfei Chen, Shuyu Hao, Z. Hou, T. Lu, Ming Sun, B. Liu · 2015 · Neuroscience
  10. Simvastatin protects ischemic spinal cord injury from cell death and cytotoxicity through decreasing oxidative stress: in vitro primary cultured rat spinal cord model under oxygen and glucose deprivation-reoxygenation conditions
    Hye-Min Sohn, Jin‐Young Hwang, Jung‐Hee Ryu, Jinhee Kim, Seong-Joo Park, Jin-woo Park, Sung‐Hee Han · 2017 · Journal of Orthopaedic Surgery and Research
  11. Perioperative Management of Severe Traumatic Brain Injury: What Is New?
    Deacon Farrell, Audrée A. Bendo · 2018 · Current anesthesiology reports
  12. Exploring Pharmacological Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Traumatic Brain Injury via a Network Pharmacology Approach
    Yuanyuan Zhong, Jiekun Luo, Tao Tang, Pengfei Li, Tao Liu, Hanjin Cui, Yang Wang, Zebing Huang · 2018 · Evidence-based Complementary and Alternative Medicine
  13. A Systematic Review of ASL Perfusion MRI in Mild TBI
    Yang Wang, Hannah M Bartels, Lindsay D. Nelson · 2020 · Neuropsychology Review
  14. Administration of all‐transretinoic acid after experimental traumatic brain injury is brain protective
    Regina Hummel, Sebastian Ulbrich, Dominik Appel, Shuailong Li, Tobias Hirnet, Sonja Zander, Wieslawa Bobkiewicz, Christina Gölz, Michael K. E. Schäfer · 2020 · British Journal of Pharmacology
  15. The role of the microbiota–gut–brain axis in long‐term neurodegenerative processes following traumatic brain injury
    Li Shan Chiu, Ryan S. Anderton · 2022 · European Journal of Neuroscience
  16. Multiple beneficial effects of melanocortin MC4 receptor agonists in experimental neurodegenerative disorders: Therapeutic perspectives
    Giuliani, Daniela, Ottani, Alessandra, Neri, Laura, Zaffe, Davide, Grieco, Paolo, Jochem, Jerzy, Cavallini, Gian Maria, Catania, Anna, Guarini, Salvatore · 2017 · Progress in Neurobiology
  17. Application of Tauroursodeoxycholic Acid for Treatment of Neurological and Non-neurological Diseases: Is There a Potential for Treating Traumatic Brain Injury?
    Kyle R. Gronbeck, Cecília M. P. Rodrigues, Javad Mahmoudi, Eric M. Bershad, Geoffrey S.F. Ling, Salam P. Bachour, Afshin A. Divani · 2016 · Neurocritical Care
  18. Pathway-Focused PCR Array Profiling of Enriched Populations of Laser Capture Microdissected Hippocampal Cells after Traumatic Brain Injury
    Deborah R. Boone, Maria‐Adelaide Micci, Isabella G. Taglialatela, Judy L Hellmich, Harris A. Weisz, Min Bi, Donald S. Prough, Douglas S. DeWitt, Helen L. Hellmich · 2015 · PLoS ONE
  19. Magnetic Resonance Imaging Pilot Study of Intravenous Glyburide in Traumatic Brain Injury
    Howard M. Eisenberg, Martha Elizabeth Shenton, Ofer Pasternak, J. Marc Simard, David O. Okonkwo, Christina Aldrich, Feng He, Sonia Jain, Erik G. Hayman · 2019 · Journal of Neurotrauma
  20. Efficacy and safety of erythropoietin for traumatic brain injury
    Motao Liu, Amy J. Wang, Yu Chen, Gexin Zhao, Zhifeng Jiang, Xinbang Wang, Dongliang Shi, Tiansong Zhang, Bomin Sun, Hua He et al. · 2020 · BMC Neurology
  21. Eccentric training effects for patients with post-stroke hemiparesis on strength and speed gait: A randomized controlled trial
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  22. Functional suppression of Ripk1 blocks the NF-κB signaling pathway and induces neuron autophagy after traumatic brain injury
    Jun Liu, Zhengkun Zhu, Leibo Wang, Jixiang Du, Biao Zhang, Xuequan Feng, Guobin Zhang · 2020 · Molecular and Cellular Biochemistry
  23. High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: Proof-of-concept
    Joshua W. Gatson, James W. Simpkins, Victor V. Uteshev · 2015 · Brain Research Bulletin
  24. microRNA-22 attenuates neuronal cell apoptosis in a cell model of traumatic brain injury.
    Ji Ma, Shaofeng Shui, Xinwei Han, Dong Guo, Tengfei Li, Lei Yan · 2016 · PubMed Central
  25. Hyperoxia results in increased aerobic metabolism following acute brain injury
    Arnab Ghosh, David Highton, Christina Kolyva, Ilias Tachtsidis, Clare E. Elwell, Martin Smith · 2016 · Journal of Cerebral Blood Flow & Metabolism
  26. Autoantibodies in traumatic brain injury and central nervous system trauma
    Mohamad Raad, Eden A. Nohra, Nour Chams, M. Itani, Farid Ramzi Talih, Stefania Mondello, Firas H. Kobeissy · 2014 · Neuroscience
  27. Efficacy, Dosage, and Duration of Action of Branched Chain Amino Acid Therapy for Traumatic Brain Injury
    Jaclynn A. Elkind, Miranda M. Lim, Brian N. Johnson, Chris P. Palmer, Brendan J. Putnam, Matthew P. Kirschen, Akiva S. Cohen · 2015 · Frontiers in Neurology
  28. Melanocortins as potential therapeutic agents in severe hypoxic conditions
    Daniela Giuliani, Letteria Minutoli, Alessandra Ottani, Luca Spaccapelo, Alessandra Bitto, Maria Galantucci, Domenica Altavilla, Francesco Squadrito, Salvatore Guarini · 2012 · Frontiers in Neuroendocrinology
  29. Combination of Temperature-Sensitive Stem Cells and Mild Hypothermia: A New Potential Therapy for Severe Traumatic Brain Injury
    Yue Tu, Chong Chen, Hongtao Sun, Shixiang Cheng, Xiaozhi Liu, Yang Qu, Xiao-hong Li, Sai Zhang · 2012 · Journal of Neurotrauma
  30. Pediatric Traumatic Brain Injury and Autism: Elucidating Shared Mechanisms
    Rahul Soloman Singh, Ryan Coddington Turner, Linda Nguyen, Kartik Motwani, Michelle Swatek, Brandon Peter Lucke-Wold · 2016 · Behavioural Neurology
  31. Efficacy of progesterone for moderate to severe traumatic brain injury: a meta-analysis of randomized clinical trials
    Chao Lin, H. He, Zheng Li, Yinglong Liu, Honglu Chao, Jing Ji, Ning Liu · 2015 · Scientific Reports
  32. A single dose of PPARγ agonist pioglitazone reduces cortical oxidative damage and microglial reaction following lateral fluid percussion brain injury in rats
    Kristina Pilipović, Željko Župan, Petra Dolenec, Jasenka Mršić‐Pelčić, Gordana Župan · 2015 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
  33. What are the progesterone-induced changes of the outcome and the serum markers of injury, oxidant activity and inflammation in diffuse axonal injury patients?
    B. Mofid, Z. Soltani, M. Khaksari, N. Shahrokhi, N. Nakhaee, S. Karamouzian, M. Ahmadinejad, Masoud Maiel, P. Khazaeli · 2016 · International Immunopharmacology
  34. Clinical Management in Traumatic Brain Injury
    Amy Yan, Andrew P. Torpey, Erin Morrisroe, Wesam Andraous, Ana Costa, Sergio Daniel Bergese · 2024 · Biomedicines
  35. Intravenous administration of Honokiol provides neuroprotection and improves functional recovery after traumatic brain injury through cell cycle inhibition
    Haiquan Wang, Zhengbu Liao, Xiaochuan Sun, Quanhong Shi, Gang Huo, Yanfeng Xie, Xiaolan Tang, Xinggang Zhi, Zhaohua Tang · 2014 · Neuropharmacology
  36. Subacute Intranasal Administration of Tissue Plasminogen Activator Promotes Neuroplasticity and Improves Functional Recovery following Traumatic Brain Injury in Rats
    Yuling Meng, Michael Chopp, Yanlu Zhang, Zhongwu Liu, An Aaron, Asim Mahmood, Ye Xiong · 2014 · PLoS ONE
  37. A Novel Role for the Endocannabinoid System in Ameliorating Motivation for Alcohol Drinking and Negative Behavioral Affect after Traumatic Brain Injury in Rats
    Elizabeth A. Fucich, Jacques P. Mayeux, Mary Adrienne McGinn, Nicholas W. Gilpin, Scott Edwards, Patricia E. Molina · 2019 · Journal of Neurotrauma
  38. Monitoring Functional Impairment and Recovery after Traumatic Brain Injury in Rats by fMRI
    Juha‐Pekka Niskanen, Antti M. Airaksinen, Alejandra Sierra, Joanna K. Huttunen, Jari Nissinen, Pasi A. Karjalainen, Asla Pitkänen, Olli H.J. Gröhn · 2012 · Journal of Neurotrauma
  39. Exploiting blood-based biomarkers to align preclinical models with human traumatic brain injury
    Ilaria Lisi, Federico Moro, Edoardo Mazzone, Niklas Marklund, Francesca Pischiutta, Firas H. Kobeissy, Xiang Mao, Frances Corrigan, Adel E Helmy, Fatima Ali Nasrallah et al. · 2024 · Brain
  40. Rapid loading and prolonged release of latanoprost from a silicone hydrogel contact lens
    Ryan R. Horne, Kevin E. Judd, William George Pitt · 2017 · Journal of Drug Delivery Science and Technology
  41. Expression signatures of long non-coding RNA and mRNA in human traumatic brain injury
    Yuhai Wang, Likun Yang, Jie Zhu, Jun-Hui Chen, Yu-Hai Wang, Kun Xiong · 2019 · Neural Regeneration Research
  42. Alantolactone plays neuroprotective roles in traumatic brain injury in rats via anti-inflammatory, anti-oxidative and anti-apoptosis pathways.
    Xun Wang, Yu‐Long Lan, Jinshan Xing, Xiaoqiang Lan, Litao Wang, Bo Zhang · 2018 · PubMed Central
  43. (-)-Epigallocatechin-3-gallate provides neuroprotection via AMPK activation against traumatic brain injury in a mouse model
    Yinyin Wu, Jing Cui · 2020 · Naunyn-Schmiedeberg s Archives of Pharmacology
  44. Treatment With 2-Pentadecyl-2-Oxazoline Restores Mild Traumatic Brain Injury-Induced Sensorial and Neuropsychiatric Dysfunctions
    Serena Boccella, Monica Iannotta, Claudia Cristiano, Fabio Arturo Iannotti, Fabio Del Bello, Francesca Guida, Carmela Belardo, Rosmara Infantino, Flavia Ricciardi, Mario Giannella et al. · 2020 · Frontiers in Pharmacology
  45. Hub genes and key pathways of traumatic brain injury: bioinformatics analysis and in vivo validation
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  46. RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in rats
    Haibo Ni, Rui Qin, Yitian Xu, Jun Zhu, Fan Gao, Baoqi Dang, Di Li, Rong Gao, Gang Chen · 2018 · Experimental Neurology
  47. Upregulation of miRNA‐223‐3p ameliorates RIP3‐mediated necroptosis and inflammatory responses via targeting RIP3 after spinal cord injury
    Yang Wang, Jianhang Jiao, Pengfei Ren, Minfei Wu · 2019 · Journal of Cellular Biochemistry
  48. Histological Quantitation of Brain Injury Using Whole Slide Imaging: A Pilot Validation Study in Mice
    Zhenzhou Chen, Dmitriy Shin, Shanyan Chen, Mikhail Kovalenko, Orr Hadass, Brittany N. Tomlison, Dmitry Korkin, Chi‐Ren Shyu, Jiankun Cui, Douglas C. Anthony et al. · 2014 · PLoS ONE
  49. A meta-analysis of efficacy in pre-clinical human stem cell therapies for traumatic brain injury
    Janessa Chang, Michael J Phelan, Brian J Cummings · 2015 · Experimental Neurology
  50. Early preservation of mitochondrial bioenergetics supports both structural and functional recovery after neurotrauma
    Bridgette D. Semple · 2014 · Experimental Neurology
  51. Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response
    Ley‐Hian Low, Yuh-Lit Chow, Yijia Li, Choo‐Peng Goh, Ulrich Putz, John Silke, Toru Ouchi, Jason A. Howitt, Seong‐Seng Tan · 2015 · Journal of Biological Chemistry
  52. Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational research
    Michael R. Grovola, Catherine R. von Reyn, David J. Loane, D. Kacy Cullen · 2023 · Journal of Neuroinflammation
  53. Selective small-molecule inhibitors as chemical tools to define the roles of matrix metalloproteinases in disease
    Jayda E. Meisel, Mayland Chang · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  54. Potential of different cells-derived exosomal microRNA cargos for treating spinal cord injury
    Dayu Pan, Weixiao Liu, Shibo Zhu, Baoyou Fan, Nanxi Yu, Guangzhi Ning, Shiqing Feng · 2021 · Journal of Orthopaedic Translation
  55. Nuclear trafficking of Pten after brain injury leads to neuron survival not death
    Choo‐Peng Goh, Ulrich Putz, Jason A. Howitt, Ley‐Hian Low, Jenny Margaret Gunnersen, Nicole Bye, Maria Cristina Morganti-Kossmann, Seong‐Seng Tan · 2013 · Experimental Neurology
  56. Acute Cortical Transhemispheric Diaschisis after Unilateral Traumatic Brain Injury
    Florie Le Prieult, Serge Christian Thal, Kristin Engelhard, Barbara Imbrosci, Thomas Mittmann · 2016 · Journal of Neurotrauma
  57. RETRACTED ARTICLE: Downregulated lncRNA CRNDE contributes to the enhancement of nerve repair after traumatic brain injury in rats
    Min Yi, Xingping Dai, Qiuxia Li, Xia Xu, Yanyi Chen, Dongsheng Wang · 2019 · Cell Cycle · Retracted
  58. Drosophila as a model to explore secondary injury cascades after traumatic brain injury
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  59. The Complexity of the Blood-Brain Barrier and the Concept of Age-Related Brain Targeting: Challenges and Potential of Novel Solid Lipid-Based Formulations
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  60. Downregulation of Homer1b/c improves neuronal survival after traumatic neuronal injury.
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  61. Understanding the Pathophysiology of Traumatic Brain Injury and the Mechanisms of Action of Neuroprotective Interventions
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  62. Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in rats
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  63. Beyond the Direct Activation of Cannabinoid Receptors: New Strategies to Modulate the Endocannabinoid System in CNS-Related Diseases
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  64. MicroRNA-21 in the Pathogenesis of Traumatic Brain Injury
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  65. Progesterone Treatment Shows Benefit in Female Rats in a Pediatric Model of Controlled Cortical Impact Injury
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  66. Glutamate Excitotoxicity: A Key Secondary Injury Mechanism of Traumatic Brain Injury and Spinal Cord Injury
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  67. Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice.
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  68. Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery: Design and Methods
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  69. Utilizing pharmacotherapy and mesenchymal stem cell therapy to reduce inflammation following traumatic brain injury
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  70. Targeting different pathophysiological events after traumatic brain injury in mice: Role of melatonin and memantine
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  71. Neuroprotective effect of breviscapine on traumatic brain injury in rats associated with the inhibition of GSK3β signaling pathway
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  72. Decompressive Craniectomy Is Associated With Good Quality of Life Up to 10 Years After Rehabilitation From Traumatic Brain Injury
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  75. Dynamic change of SGK expression and its role in neuron apoptosis after traumatic brain injury.
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