The DOI matches its Crossref record; 102 of the 102 references it cites were found in a registry or an index.
Population size and the rate of evolution
Open accessAbstract
Does evolution proceed faster in larger or smaller populations? The relationship between effective population size (Ne) and the rate of evolution has consequences for our ability to understand and interpret genomic variation, and is central to many aspects of evolution and ecology. Many factors affect the relationship between Ne and the rate of evolution, and recent theoretical and empirical studies have shown some surprising and sometimes counterintuitive results. Some mechanisms tend to make the relationship positive, others negative, and they can act simultaneously. The relationship also depends on whether one is interested in the rate of neutral, adaptive, or deleterious evolution. Here, we synthesize theoretical and empirical approaches to understanding the relationship and highlight areas that remain poorly understood.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Neutral Theory of Molecular Evolution
Kimura, M. (1979) · Scientific American · doi:10.1038/scientificamerican1179-98 · Cited by 7,666
The distribution of fitness effects of new mutations
Eyre-Walker, A., & Keightley, P. D. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2146 · Cited by 1,478
Self-citationEffective population size/adult population size ratios in wildlife: a review
Frankham, R. (1995) · Genetical Research · doi:10.1017/s0016672300034455 · Cited by 1,370
The neutral theory of molecular evolution
Dover, G. A. (1984) · Endeavour · doi:10.1016/0160-9327(84)90064-4 · Cited by 1,369
Evolutionary dynamics on graphs
Lieberman, E., Hauert, C., & Nowak, M. A. (2005) · Nature · doi:10.1038/nature03204 · Cited by 1,337
A Mathematical Theory of Natural and Artificial Selection, Part V: Selection and Mutation
Haldane, J. B. S. (1927) · Mathematical Proceedings of the Cambridge Philosophical Society · doi:10.1017/s0305004100015644 · Cited by 1,326
Faircloth, B. C., McCormack, J. E., Crawford, N. G., Harvey, M. G., Brumfield, R. T., & Glenn, T. C. (2012) · Systematic Biology · doi:10.1093/sysbio/sys004 · Cited by 1,270
Evolution of the mutation rate
Lynch, M. (2010) · Trends in Genetics · doi:10.1016/j.tig.2010.05.003 · Cited by 1,151
The Nearly Neutral Theory of Molecular Evolution
Ohta, T. (1992) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.23.110192.001403 · Cited by 1,149
The Origins of Genome Architecture
Abdel-Haleem, H. (2007) · Journal of Heredity · doi:10.1093/jhered/esm073 · Cited by 1,139
Cited by
Limits of long-term selection against Neandertal introgression
Petr, M., Pääbo, S., Kelso, J., & Vernot, B. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1814338116 · Cited by 211
Gene tree discordance causes apparent substitution rate variation
Mendes, F. K., & Hahn, M. W. (2016) · Systematic Biology · doi:10.1093/sysbio/syw018 · Cited by 189
Island songbirds as windows into evolution in small populations
Leroy, T., Rousselle, M., Tilak, M.-K., Caizergues, A. E., Scornavacca, C., Recuerda, M., Fuchs, J., Illera, J. C., De Swardt, D. H., Blanco, G., et al. (2021) · Current Biology · doi:10.1016/j.cub.2020.12.040 · Cited by 113
AAV Ancestral Reconstruction Library Enables Selection of Broadly Infectious Viral Variants
Santiago-Ortiz, J., Ojala, D. S., Westesson, O., Weinstein, J. R., Wong, S. Y., Steinsapir, A., Kumar, S., Holmes, I., & Schaffer, D. V. (2015) · Gene Therapy · doi:10.1038/gt.2015.74 · Cited by 83
Ramstein, G. P., & Buckler, E. S. (2022) · Genome Biology · doi:10.1186/s13059-022-02747-2 · Cited by 34
Metadata
- Authors
- Lanfear, R., Kokko, H., & Eyre-Walker, A.
- Venue
- Trends in Ecology & Evolution
- Publisher
- Elsevier BV
- Published
- 2014-01
- Volume
- 29
- Issue
- 1
- Pages
- 33-41
- ISSN
- 0169-5347 (ISSN-L)
- OpenAlex
- W2000063205
- Cited by
- 431
- References
- 102
- FWCI
- 3.29
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Population size and the rate of evolution. https://app.cochat.ai/papers/10.1016/j.tree.2013.09.009
- The paper
- Lanfear, R., Kokko, H., & Eyre-Walker, A. (2014). Population size and the rate of evolution. Trends in Ecology & Evolution. https://doi.org/10.1016/j.tree.2013.09.009
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
