Comparison between the indocyanine green fluorescence and blue dye methods for sentinel lymph node biopsy using novel fluorescence image-guided resection equipment in different types of hospitals
Abstract
Sentinel lymph node biopsy (SLNB) has become a standard of care to detect axillary lymph metastasis in early-stage breast cancer patients with clinically negative axillary lymph nodes. Current SLNB detection modalities comprising a blue dye, a radioactive tracer, or a combination of both have advantages as well as disadvantages. Thus, near-infrared fluorescence imaging using indocyanine green (ICG) has recently been regarded as a novel method that has generated interest for SLNB around the world. However, the lack of appropriate fluorescence imaging systems has hindered further research and wide application of this method. Therefore, we developed novel fluorescence image-guided resection equipment (FIRE) to detect sentinel lymph nodes (SLNs). Moreover, to compare the ICG fluorescence imaging method with the blue dye method and to explore the universal feasibility of the former, a different type of hospital study was conducted. Ninety-nine eligible patients participated in the study at 3 different types of hospitals. After subcutaneous ICG allergy testing, all the patients were subcutaneously injected with methylene blue and ICG into the subareolar area. Consequently, 276 SLNs (range 1-7) were identified in 98 subjects (detection rate: 99%) by using the ICG fluorescence imaging method. In contrast, the blue dye method only identified 202 SLNs (range 1-7) in 91 subjects (detection rate: 91.92%). Besides, the results of the fluorescence imaging method were similar in the 3 hospi…
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Clinically approved agents available for tumor detection and therapy remain extremely limited, with examples including methylene blue and indocyanine green.
“Despite the significant advantages of organic small-molecule fluorescent probes, clinically approved agents available for tumor detection and therapy remain extremely limited (e.g., methylene blue, indocyanine green (ICG))63–66.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [63]
Cites
Krag, D. N., Anderson, S., Julian, T. B., Brown, A. M., Harlow, S. P., Costantino, J. P., Ashikaga, T., Weaver, D. L., Mamounas, E. P., Jalovec, L. M., et al. (2010) · The Lancet Oncology · doi:10.1016/s1470-2045(10)70207-2 · Cited by 1,923 · see citing works
Real‐time identification of liver cancers by using indocyanine green fluorescent imaging
Ishizawa, T., Fukushima, N., Shibahara, J., Masuda, K., Tamura, S., Aoki, T., Hasegawa, K., Beck, Y., Fukayama, M., & Kokudo, N. (2009) · Cancer · doi:10.1002/cncr.24291 · Cited by 857 · see citing works
Schaafsma, B. E., Mieog, J. S. D., Hutteman, M., van der Vorst, J. R., Kuppen, P. J. K., Löwik, C. W. G. M., Frangioni, J. V., van de Velde, C. J. �., & Vahrmeijer, A. L. (2011) · Journal of Surgical Oncology · doi:10.1002/jso.21943 · Cited by 814 · see citing works
Troyan, S. L., Kianzad, V., Gibbs‐Strauss, S. L., Gioux, S., Matsui, A., Oketokoun, R., Ngo, L. H., Khamene, A., Azar, F. S., & Frangioni, J. V. (2009) · Annals of Surgical Oncology · doi:10.1245/s10434-009-0594-2 · Cited by 685 · see citing works
Chi, C., Du, Y., Ye, J., Kou, D., Qiu, J., Wang, J., Tian, J., & Chen, X. S. (2014) · Theranostics · doi:10.7150/thno.9899 · Cited by 360 · see citing works
Self-citationGotoh, K., Yamada, T., Ishikawa, O., Takahashi, H., Eguchi, H., Yano, M., Ohigashi, H., Tomita, Y., Miyamoto, Y., & Imaoka, S. (2009) · Journal of Surgical Oncology · doi:10.1002/jso.21272 · Cited by 331 · see citing works
Zavagno, G., Salvo, G. L. D., Scalco, G., Bozza, F. A., Barutta, L., Bianco, P. D., Renier, M., Racano, C., Carraro, P., & Nitti, D. (2008) · Annals of Surgery · doi:10.1097/sla.0b013e31812e6a73 · Cited by 314 · see citing works
Mieog, J. S. D., Troyan, S. L., Hutteman, M., Donohoe, K. J., van der Vorst, J. R., Stockdale, A., Liefers, G., Choi, H. S., Gibbs‐Strauss, S. L., Putter, H., et al. (2011) · Annals of Surgical Oncology · doi:10.1245/s10434-011-1566-x · Cited by 250 · see citing works
Google Glass in pediatric surgery: An exploratory study
Muensterer, O. J., Lacher, M., Zoeller, C., Bronstein, M. E., & Kübler, J. F. (2014) · International Journal of Surgery · doi:10.1016/j.ijsu.2014.02.003 · Cited by 249 · see citing works
Sentinel Node Identification Rate and Nodal Involvement in the EORTC 10981-22023 AMAROS Trial
Straver, M. E., Meijnen, P., van Tienhoven, G., van de Velde, C. J. �., Mansel, R. E., Bogaerts, J., Duez, N. J., Cataliotti, L., Klinkenbijl, J. H. G., Westenberg, H., et al. (2010) · Annals of Surgical Oncology · doi:10.1245/s10434-010-0945-z · Cited by 247 · see citing works
Learning sentinel node biopsy: Results of a prospective randomized trial of two techniques
Morrow, M., RADEMAKER, A. W., Bethke, K. P., Talamonti, M., Dawes, L. G., Clauson, J., & Hansen, N. M. (1999) · Surgery · doi:10.1016/s0039-6060(99)70127-3 · Cited by 215 · see citing works
Thevarajah, S., Huston, T. L., & Simmons, R. M. (2005) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2004.06.042 · Cited by 212 · see citing works
Cahill, R. A., Anderson, M., Wang, L. M., Lindsey, I., Cunningham, C., & Mortensen, N. (2011) · Surgical Endoscopy · doi:10.1007/s00464-011-1854-3 · Cited by 164 · see citing works
van der Vorst, J. R., Schaafsma, B. E., Verbeek, F. P. R., Hutteman, M., Mieog, J. S. D., Löwik, C. W. G. M., Liefers, G., Frangioni, J. V., van de Velde, C. J. �., & Vahrmeijer, A. L. (2012) · Annals of Surgical Oncology · doi:10.1245/s10434-012-2466-4 · Cited by 137 · see citing works
Cox, C. E., Dupont, E. L., Whitehead, G. F., Ebert, M. D., Nguyen, K., Peltz, E. S., Peckham, D., Cantor, A. B., & Reintgen, D. S. (2002) · The Breast Journal · doi:10.1046/j.1524-4741.2002.08203.x · Cited by 135 · see citing works
Shoulder and arm morbidity in sentinel node-negative breast cancer patients: a systematic review
Verbelen, H., Gebruers, N., Eeckhout, F.-M., Verlinden, K., & Tjalma, W. A. A. (2014) · Breast Cancer Research and Treatment · doi:10.1007/s10549-014-2846-5 · Cited by 124 · see citing works
Połom, K., Murawa, D., Nowaczyk, P., Rho, Y. S., & Murawa, P. (2011) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2011.11.004 · Cited by 72 · see citing works
Chi, C., Ye, J., Ding, H., He, D., Huang, W., Zhang, G., & Tian, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083927 · Cited by 71 · see citing works
Self-citationSugie, T., Kassim, K., Takeuchi, M., Hashimoto, T., Yamagami, K., Masai, Y., & Toi, M. (2010) · Cancers · doi:10.3390/cancers2020713 · Cited by 68 · see citing works
Akers, W. J., Edwards, W. B., Kim, C., Xu, B. J., Erpelding, T. N., Wang, L. V., & Achilefu, S. A. (2011) · Translational research · doi:10.1016/j.trsl.2011.09.006 · Cited by 67 · see citing works
Indocyanine green fluorescence mapping for sentinel lymph node biopsy in early breast cancer
Pitsinis, V., Provenzano, E., Kaklamanis, L., Wishart, G. C., & Benson, J. R. (2015) · Surgical Oncology · doi:10.1016/j.suronc.2015.10.002 · Cited by 64 · see citing works
Hirche, C. R., Engel, H., Kolios, L., Cognié, J., Hünerbein, M., Lehnhardt, M., & Kremer, T. L. (2012) · Surgical Innovation · doi:10.1177/1553350612468962 · Cited by 60 · see citing works
Toh, U., Iwakuma, N., Mishima, M., Okabe, M., Nakagawa, S., & Akagi, Y. (2015) · Breast Cancer Research and Treatment · doi:10.1007/s10549-015-3542-9 · Cited by 58 · see citing works
Liu, Y., Zhao, Y.-M., Akers, W. J., Tang, Z., Fan, J., Sun, H., Ye, Q., Wang, L., & Achilefu, S. A. (2013) · Translational research · doi:10.1016/j.trsl.2013.05.002 · Cited by 50 · see citing works
Impact of sentinel node biopsy on long-term quality of life in breast cancer patients
Gournay, E. D., Guyomard, A., Coutant, C., Boulet, S., Arveux, P., Causeret, S., Gouy, S., Padeano, M.-M., Loustalot, C., Jm, S., et al. (2013) · British Journal of Cancer · doi:10.1038/bjc.2013.658 · Cited by 46 · see citing works
Ram, R., Singh, J., & McCaig, E. (2014) · International Journal of Breast Cancer · doi:10.1155/2014/513780 · Cited by 37 · see citing works
Results of a national training programme in sentinel lymph node biopsy for breast cancer
surgeons, T. S. G. B., Mansel, R. E., MacNeill, F. A., Horgan, K. J., Goyal, A., Britten, A. J., Townson, J. K., Clarke, D., Newcombe, R. G., & Keshtgar, M. (2013) · British journal of surgery · doi:10.1002/bjs.9058 · Cited by 36 · see citing works
Cabon, Q., Sayag, D., Texier, I., Navarro, F. P., Boisgard, R., Watrelot-Virieux, D., Ponce, F., & Carozzo, C. (2015) · Translational research · doi:10.1016/j.trsl.2015.12.001 · Cited by 29 · see citing works
Mathematical method in optical molecular imaging
Leng, C., & Tian, J. (2015) · Science China Information Sciences · doi:10.1007/s11432-014-5222-5 · Cited by 27 · see citing works
Self-citationAn alternative to initial axillary-lymph-node dissection
Benson, J. R. (2010) · The Lancet Oncology · doi:10.1016/s1470-2045(10)70220-5 · Cited by 13 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
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Wang, K., Du, Y., Zhang, Z., He, K., Cheng, Z., Yin, L., Dong, D., Li, C., Li, W., Hu, Z., et al. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-022-00017-1 · Cited by 244 · see citing works
Self-citationLi, D., Zhang, J., Chi, C., Xiao, X., Wang, J., Lang, L., Ali, I., Niu, G., Zhang, L., Tian, J., et al. (2018) · Theranostics · doi:10.7150/thno.25599 · Cited by 154 · see citing works
Self-citationKedrzycki, M. S., Leiloglou, M., Ashrafian, H., Jiwa, N., Thiruchelvam, P. T. R., Elson, D. S., & Leff, D. R. (2020) · Annals of Surgical Oncology · doi:10.1245/s10434-020-09288-7 · Cited by 92 · see citing works
Intraoperative evaluation of perfusion in free flap surgery: A systematic review and meta‐analysis
Smit, J. M., Negenborn, V. L., Jansen, S. M., Jaspers, M. E. H., de Vries, R., Heymans, M. W., Winters, H. A. H., van Leeuwen, T. G. J. M., Mullender, M. G., & Krekel, N. M. A. (2018) · Microsurgery · doi:10.1002/micr.30320 · Cited by 79 · see citing works
Ai, T., Shang, W., Yan, H., Zeng, C., Wang, K., Gao, Y., Guan, T., Fang, C., & Tian, J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.01.031 · Cited by 74 · see citing works
Self-citationJeremiasse, B., van den Bosch, C. H., Wijnen, M. W. H. A., van Scheltinga, C. E. J. T., Fiocco, M. F., & van der Steeg, A. F. W. (2020) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2020.07.012 · Cited by 60 · see citing works
Wang, Q., Yan, H., Jin, Y., Wang, Z., Huang, W., Qiu, J., Kang, F., Wang, K., Zhao, X., & Tian, J. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.08.048 · Cited by 59 · see citing works
Self-citationHe, K., Zhou, J. H., Yang, F., Chi, C., Li, H., Mao, Y., Hui, B., Wang, K., Tian, J., & Wang, J. (2017) · Theranostics · doi:10.7150/thno.22369 · Cited by 59 · see citing works
Self-citationThongvitokomarn, S., & Polchai, N. (2020) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2020.21.5.1187 · Cited by 53 · see citing works
Mao, Y., Chi, C., Yang, F., Zhou, J. H., He, K., Li, H., Chen, X., Ye, J., Wang, J., & Tian, J. (2017) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezx207 · Cited by 49 · see citing works
Self-citationMulti-Wavelength Fluorescence in Image-Guided Surgery, Clinical Feasibility and Future Perspectives
van Beurden, F., van Willigen, D. M., Vojnovic, B., van Oosterom, M. N., Brouwer, O. R., van der Poel, H. G., Kobayashi, H., van Leeuwen, F. W. B., & Buckle, T. (2020) · Molecular Imaging · doi:10.1177/1536012120962333 · Cited by 48 · see citing works
Villegas-Tovar, E., Jiménez-Lillo, J., Jimenez-Valerio, V., Díaz-Girón-Gidi, A., Faes-Petersen, R., Piñeiro, A. O., de Lacy, F. B., Martinez-Portilla, R. J., & Lacy, A. M. (2019) · Surgical Endoscopy · doi:10.1007/s00464-019-07274-z · Cited by 47 · see citing works
Zhang, C., Jiang, D., Huang, B., Wang, C., Zhao, L., Xie, X., Zhang, Z., Wang, K., Tian, J., & Luo, Y. (2019) · Technology in Cancer Research & Treatment · doi:10.1177/1533033819894331 · Cited by 46 · see citing works
Self-citationWang, Z., Cui, Y., Zheng, M., Ge, H., Huang, Y., Peng, J., Xie, H., & Wang, S. (2020) · Gland Surgery · doi:10.21037/gs-20-671 · Cited by 42 · see citing works
Borlan, R., Focşan, M., Maniu, D., & Aştilean, S. (2021) · International Journal of Nanomedicine · doi:10.2147/ijn.s295234 · Cited by 41 · see citing works
Jiménez-Lillo, J., Villegas-Tovar, E., Momblan, D. N. D. M., Turrado-Rodriguez, V., Ainitze, I., de Lacy, B., Díaz-Girón-Gidi, A., Faes-Petersen, R., Martinez-Portilla, R. J., & Lacy, A. M. (2021) · Annals of Surgical Oncology · doi:10.1245/s10434-021-09617-4 · Cited by 38 · see citing works
He, K., Chi, C., Li, D., Zhang, J., Niu, G., Lv, F., Wang, J., Che, W., Zhang, L., Ji, N., et al. (2020) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10182 · Cited by 32 · see citing works
Self-citationHe, K., Hong, X., Chi, C., Cai, C., Wang, K., Li, P., Liu, X., Li, J., Shan, H., & Tian, J. (2020) · Surgical Endoscopy · doi:10.1007/s00464-019-07290-z · Cited by 31 · see citing works
Self-citationWhite, K. P., Sinagra, D. L., Dip, F., Rosenthal, R. J., Mueller, E. A., Menzo, E. L., & Rancati, A. O. (2023) · Surgery · doi:10.1016/j.surg.2023.10.021 · Cited by 29 · see citing works
Ersoy, Y. E., & Kadioğlu, H. (2018) · Clinical Breast Cancer · doi:10.1016/j.clbc.2018.01.004 · Cited by 29 · see citing works
Mathelin, C., & Lodi, M. (2020) · Chinese Clinical Oncology · doi:10.21037/cco-20-207 · Cited by 22 · see citing works
Near-infrared fluorescence imaging-guided lymphatic mapping in thoracic esophageal cancer surgery
Wang, X., Hu, Y., Wu, X.-W., Liang, M., Hu, Z., Gan, X., Li, D., Cao, Q., & Shan, H. (2021) · Surgical Endoscopy · doi:10.1007/s00464-021-08720-7 · Cited by 21 · see citing works
Mao, Y., Wang, K., He, K., Ye, J., Yang, F., Zhou, J. H., Li, H., Chen, X., Wang, J., Chi, C., et al. (2017) · Journal of Biomedical Optics · doi:10.1117/1.jbo.22.6.066002 · Cited by 17 · see citing works
Self-citationOrganic small-molecule NIR-II fluorophores for tumor phototheranostics
Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22 · see citing works
“Despite the signi fi cant advantages of organic small-molecule fl uorescent probes, clinically approved agents available for tumor detection and therapy remain extremely limited (e.g., methylene blue, indocyanine green (ICG)) 63 – 66 .”
Wang, Y., Zhao, G., Liu, Y., Wang, R., Xing, Y., Dou, K., & Yu, F. (2025) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2024.137005 · Cited by 16 · see citing works
Self-citationJin, Y., Yuan, L., Zhang, Y., Tang, P., Yang, Y., Fan, L., Chen, L., Qi, X., & Jiang, J. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.803804 · Cited by 13 · see citing works
Muhanna, N., Chan, H. H. L., Douglas, C. M., Daly, M. J., Jaidka, A., Eu, D., Bernstein, J. M., Townson, J. L., & Irish, J. C. (2020) · BMC Medical Imaging · doi:10.1186/s12880-020-00507-x · Cited by 12 · see citing works
Mela, C. A., Papay, F., & Liu, Y. (2021) · IEEE photonics journal · doi:10.1109/jphot.2021.3055809 · Cited by 12 · see citing works
Wang, P., Shuai, J., Leng, Z.-F., & Ji, Y. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103742 · Cited by 11 · see citing works
10 % fluorescein sodium vs 1 % isosulfan blue in breast sentinel lymph node biopsy
Ren, L., Liu, Z., Liang, M., Wang, L., Song, X., & Wang, S. (2016) · World Journal of Surgical Oncology · doi:10.1186/s12957-016-1031-1 · Cited by 10 · see citing works
Litchinko, A., Meyer, J., Bühler, L. H., Ris, F., & Adamina, M. (2025) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-025-03786-6 · Cited by 9 · see citing works
Hidar, S., Alimi, A., Khlifi, A., Chachia, S., Kaabia, O., Bouguizane, S., Bibi, M., & Khaı̈ri, H. (2021) · European Journal of Breast Health · doi:10.4274/ejbh.galenos.2021.2021-4-11 · Cited by 7 · see citing works
Vaz, T., Costa, S., & Peleteiro, B. (2018) · Acta Médica Portuguesa · doi:10.20344/amp.10395 · Cited by 6 · see citing works
Huo, Y., Fan, T., Chen, S., Liu, Q., Fang, Y., & Yao, F. (2022) · Translational Cancer Research · doi:10.21037/tcr-21-2841 · Cited by 6 · see citing works
Yap, R. V., & Serna, F. M. D. L. (2020) · Breast Cancer Targets and Therapy · doi:10.2147/bctt.s242115 · Cited by 4 · see citing works
Qian, H., Yang, M., Wang, P., Graça, L., Sun, H., & Li, C. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123779 · Cited by 3 · see citing works
Use of indocyanine green in detection of breast axillary sentinel lymph nodes
Bhakta, P. S., Farnand, A. W., Osipova, M. A., & CONNOLLY, M. M. (2020) · Annals of Breast Surgery · doi:10.21037/abs-20-22 · Cited by 3 · see citing works
Gurluler, E., Polatkan, V., Şenol, K., & Gökgöz, M. Ş. (2024) · Asian Journal of Surgery · doi:10.1016/j.asjsur.2024.07.090 · Cited by 2 · see citing works
Wang, Z., Dai, B., Zhang, J., Wu, Y., Li, Y., Cao, Y. J., You, Q., Wang, W., Singhal, S. K., Nie, S., et al. (2025) · Med-X · doi:10.1007/s44258-025-00072-4 · Cited by 1 · see citing works
Self-citationPrinciples and Practice of Intraoperative Fluorescence Imaging
Gorpas, D. S., Ntziachristos, V., & Tian, J. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-816386-3.00009-0 · Cited by 1 · see citing works
Self-citationNIR fluorophores clinically assessed for fluorescence guided surgeryPreprint
Ge, Y., & O’Shea, D. F. (2023) · ChemRxiv · doi:10.26434/chemrxiv-2023-wh8tn · Cited by 1 · see citing works
Newer Modalities for the Detection and Assessment of the Sentinel Lymph Node
Karakatsanis, A., & Kothari, A. S. (2023) · Springer eBooks · doi:10.1007/978-81-322-3994-9_8
Jia, Q., Yan, H., Jia, Y., Liu, S., Feng, Y., Chen, B., Shi, C., Xu, X., Zhang, R., & Wang, Z. (2026) · Chinese Chemical Letters · doi:10.1016/j.cclet.2026.112359
Zhang, L., Li, P., Chen, J., Huang, J., Liang, M., He, J., Liu, X., Zheng, Z., Hong, X., Zhu, G., et al. (2026) · Surgical Endoscopy · doi:10.1007/s00464-026-13233-2
Current Status and Progress of Sentinel Lymph Node Biopsy Tracers in Breast Cancer
黄, 蕾. (2026) · Advances in Clinical Medicine · doi:10.12677/acm.2026.1682989
Nida, M., Abdelmoghny, A., Osman, A. G., Abd-erRazik, M., & Hanafy, D. M. (2026) · Journal of the Egyptian National Cancer Institute · doi:10.1186/s43046-026-00403-5
- Authors
- He, K., Chi, C., Kou, D., Huang, W., Wu, J., Wang, Y., He, L., Ye, J., Mao, Y., Zhang, G.-J., Wang, J., & Tian, J.
- Affiliations
- Chinese Academy of Sciences (CN)
- Chinese People's Liberation Army (CN)
- Cancer Hospital of Shantou University Medical College (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
- Chinese PLA General Hospital (CN)
- Corresponding author
- Zhang, Guo-Jun
- Wang, Jiandong
- Tian, Jie
- Venue
- Translational Research
- Publisher
- Elsevier BV
- Published
- 2016-12
- Volume
- 178
- Pages
- 74-80
- ISSN
- 1878-1810 (ISSN-L)
- 1931-5244
- OpenAlex
- W2502843285
- Cited by
- 46
- References
- 30
- Citations by year
- 2026: 5 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 6 · 2020: 11 · 2019: 2 · 2018: 6 · 2017: 3 · 2016: 1
- FWCI
- 3.47
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Translational research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation (81227901, 81527805, 61231004, 61501462)
- International Innovation Team, CAS (20140491524)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
- Health Sciences › Medicine › Pathology and Forensic Medicine › Breast Lesions and Carcinomas
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
- Keywords
- sentinel lymph node biopsy, indocyanine green, fluorescence imaging, methylene blue, early breast cancer, axillary lymph node metastasis, sentinel lymph node detection rate, inter-hospital comparison
- MeSH terms
- Sentinel Lymph Node, Adult, Aged, Female, Fluorescence, Hospitals, Humans, Indocyanine Green, Intraoperative Care, Methylene Blue, Middle Aged, Sentinel Lymph Node Biopsy, Image-Guided Biopsy
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