Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum)

Kimbaris, Athanasios C.; Siatis, Nikolaos G.; Daferera, Dimitra J.; Tarantilis, Petros A.; Pappas, Christos S.; Polissiou, Moschos G.

doi:10.1016/j.ultsonch.2004.12.003

Cited by 281Garlic and Onion StudiesEssential Oils and Antimicrobial ActivityAnalytical chemistry methods development

Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum)

Kimbaris, Athanasios C., Siatis, Nikolaos G., Daferera, Dimitra J., Tarantilis, Petros A., Pappas, Christos S., Polissiou, Moschos G.·2006·Ultrasonics Sonochemistry

DOI 10.1016/j.ultsonch.2004.12.003

Open this paper in CoChat — free account

Abstract

A comparative study of traditional simultaneous distillation extraction (SDE), microwave assisted hydrodistillation extraction (MWHD) and ultrasound-assisted extraction (USE) is presented, for the extraction of essential oils from fresh garlic (Allium sativum) cloves. Each method is evaluated in terms of qualitative and quantitative composition of the isolated essential oil. The highly reactive sulfur molecules of the garlic volatile fraction show variable response to the different isolation methods. The application of ultrasound for the extraction of the essential oil is considered to cause a lesser damage of thermal-sensitive molecules, thus, providing a better approach of the compounds primarily responsible for the characteristic odor and taste of freshly chopped garlic. All heat-involving isolation procedures have been shown to differentiate the volatile-fraction profile as analyzed by GC-MS. Especially when grouping the compounds into cyclic and acyclic, the percentage concentrations drop from 77.4% to 8.7% for the acyclic while that of the cyclic compounds increase from 4.7% to 70.8%. The observed fact may be attributed to the effect of the heat applied, which changes from harsh thermal treatment (SDE) to short time thermal (MWHD) and room-temperature isolation (USE). The use of USE proves to be crucial in order to provide reliable insight into garlic's chemistry.

Integrity signals

Registry

Crossref · 10.1016/j.ultsonch.2004.12.003

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Organosulfur compounds are thermally unstable and naturally degraded.
“Further, those organosulfur compound was thermally unstable and naturally degraded by nature21.”
From Bioactivities of Allium longicuspis Regel against anthracnose of mango caused by Colletotrichum gloeosporioides (Penz.) (2020) · cites this paper as [21]

An overview of the ultrasonically assisted extraction of bioactive principles from herbs
Vînătoru, M. (2001) · Ultrasonics Sonochemistry · doi:10.1016/s1350-4177(01)00071-2 · Cited by 1,146 · see citing works
The Organosulfur Chemistry of the Genus Allium – Implications for the Organic Chemistry of Sulfur
Block, E. (1992) · Angewandte Chemie International Edition in English · doi:10.1002/anie.199211351 · Cited by 997 · see citing works
Allicin, the Antibacterial Principle of Allium sativum. I. Isolation, Physical Properties and Antibacterial Action
Cavallito, C. J., & Bailey, J. H. (1944) · Journal of the American Chemical Society · doi:10.1021/ja01239a048 · Cited by 736 · see citing works
The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins
Rabinkov, A., Miron, T., Konstantinovski, L., Wilchek, M., Mirelman, D., & Weiner, L. (1998) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(97)00104-9 · Cited by 426 · see citing works
Garlic as an antioxidant: the good, the bad and the ugly
Banerjee, S., Mukherjee, P. K., & Maulik, S. (2003) · Phytotherapy Research · doi:10.1002/ptr.1281 · Cited by 424 · see citing works
Human Medicinal Agents from Plants
Kinghorn, A. D., & Balandrin, M. F. (1993) · ACS symposium series · doi:10.1021/bk-1993-0534 · Cited by 367 · see citing works
The chemistry of alkyl thiosulfinate esters. 9. Antithrombotic organosulfur compounds from garlic: structural, mechanistic, and synthetic studies
Block, E., Ahmad, S., Catalfamo, J. L., Jain, M. K., & Apitz-Castro, R. J. (1986) · Journal of the American Chemical Society · doi:10.1021/ja00282a033 · Cited by 321 · see citing works
Allicin, the Antibacterial Principle of Allium sativum. II. Determination of the Chemical Structure
Cavallito, C. J., Buck, J. S., & Suter, C. M. (1944) · Journal of the American Chemical Society · doi:10.1021/ja01239a049 · Cited by 289 · see citing works
The use of ultrasound for the extraction of bioactive principles from plant materials
Vînătoru, M., Toma, M., Radu, O., Filip, P., Lăzurcă, D., & Mason, T. J. (1997) · Ultrasonics Sonochemistry · doi:10.1016/s1350-4177(97)83207-5 · Cited by 272 · see citing works
Identification and HPLC Quantitation of the Sulfides and Dialk(en)yl Thiosulfinates in Commercial Garlic Products
Lawson, L. D., Wang, Z.-Y., & Hughes, B. G. (1991) · Planta Medica · doi:10.1055/s-2006-960119 · Cited by 255 · see citing works
Microwave-assisted extraction of artemisinin from Artemisia annua L
Jin-yu, H., Han, W., Huang, S.-D., Xue, B., & Xiu, D. (2002) · Separation and Purification Technology · doi:10.1016/s1383-5866(02)00043-6 · Cited by 249 · see citing works
Flavor components of garlic extract
Brodnitz, M. H., Pascale, J. V., & Derslice, L. V. (1971) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf60174a007 · Cited by 227 · see citing works
HPLC Analysis of Allicin and Other Thiosulfinates in Garlic Clove Homogenates
Lawson, L. D., Wood, S., & Hughes, B. G. (1991) · Planta Medica · doi:10.1055/s-2006-960087 · Cited by 188 · see citing works
Über Alliin, die genuine Muttersubstanz des Knoblauchöls. 1. Mitteilung über Allium‐Substanzen
Stoll, A., & Seebeck, E. (1948) · Helvetica Chimica Acta · doi:10.1002/hlca.19480310140 · Cited by 187 · see citing works
Volatile compounds from garlic
Yu, T. H., Wu, C., & LIOU, Y. (1989) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00087a032 · Cited by 176 · see citing works
Development of Flavor, Odor, and Pungency in Onion and Garlic
Whitaker, J. R. (1976) · Advances in food research · doi:10.1016/s0065-2628(08)60337-7 · Cited by 167 · see citing works
The oil of garlic, Allium sativum L. (Amaryllidaceae), as a potential grain protectant against Tribolium castaneum (Herbst) and Sitophilus zeamais Motsch
Ho, S. H., Koh, L., Ma, Y., Huang, Y., & Sim, K. Y. (1996) · Postharvest Biology and Technology · doi:10.1016/0925-5214(96)00018-x · Cited by 139 · see citing works
S-Allylmercaptoglutathione: the reaction product of allicin with glutathione possesses SH-modifying and antioxidant properties
Rabinkov, A., Miron, T., Mirelman, D., Wilchek, M., Glozman, S., Yavin, E., & Weiner, L. M. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/s0167-4889(00)00119-1 · Cited by 137 · see citing works
Isolation and Characterization of Larvicidal Principle of Garlic
Amonkar, S. V., & Banerji, A. (1971) · Science · doi:10.1126/science.174.4016.1343 · Cited by 105 · see citing works
Über Alliin, die genuine Muttersubstanz des Knoblauchöls
Stoll, A., & Seebeck, E. (1947) · Cellular and Molecular Life Sciences · doi:10.1007/bf02137698 · Cited by 92 · see citing works
Über den enzymatischen Abbau des Alliins und die Eigenschaften der Alliinase. 2. Mitteilung über Allium‐Substanzen
Stoll, A., & Seebeck, E. (1949) · Helvetica Chimica Acta · doi:10.1002/hlca.19490320129 · Cited by 86 · see citing works
Volatile compounds of deep-oil fried, microwave-heated and oven-baked garlic slices
Yu, T. H., Wu, C., & Ho, C. T. (1993) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00029a023 · Cited by 77 · see citing works
Mosquito Control with Active Principle of Garlic, Allium sativum
Amonkar, S. V., & Reeves, E. L. (1970) · Journal of Economic Entomology · doi:10.1093/jee/63.4.1172 · Cited by 76 · see citing works
Some Organic Sulfur Compounds in Vegetables and Fodder Plants and their Significance in Human Nutrition
Virtanen, A. I. (1962) · Angewandte Chemie International Edition in English · doi:10.1002/anie.196202991 · Cited by 71 · see citing works
Über das ätherische Ol des Knoblauchs (Allium sativum)
Semmler, F. W. (1892) · Archiv der Pharmazie · doi:10.1002/ardp.18922300603 · Cited by 65 · see citing works
Volatile flavor components and antithrombotic agents: vinyldithiins from Allium victorialis L
Nishimura, H., Wijaya, C. H., & Mizutani, J. (1988) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00081a039 · Cited by 59 · see citing works
The use of the ‘Cryogenic’ GC/MS and on-column injection for study of organosulfur compounds of the Allium sativum
Abu‐Lafi, S., Dembicki, J. W., Goldshlag, P., Hanuš, L. O., & Dembitsky, V. M. (2004) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2003.09.002 · Cited by 57 · see citing works
Gasphasen‐Reaktionen, 30. Thioacrolein: Das stabilste C3H4S‐Isomere und sein PE‐spektroskopischer Nachweis in der Gasphase
Bock, H., Mohmand, S., Hirabayashi, T., & Semkow, A. (1982) · Chemische Berichte · doi:10.1002/cber.19821150410 · Cited by 55 · see citing works
Rapid analytical method for the determination of pesticide residues in sunflower seeds based on focused microwave-assisted Soxhlet extraction prior to gas chromatography–tandem mass spectrometry
Prados‐Rosales, R., Luque-García, J. L., & de Castro, M. D. L. (2003) · Journal of Chromatography A · doi:10.1016/s0021-9673(03)00396-0 · Cited by 52 · see citing works
Volatile Compounds of Blanched, Fried Blanched, and Baked Blanched Garlic Slices
Yu, T., Lin, L.-Y., & Ho, C. (1994) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00042a018 · Cited by 37 · see citing works
Volatile Compounds in Stir-Fried Garlic
Kim, S. M., Wu, C., Kobayashi, A., Kubota, K., & Okumura, J. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00059a033 · Cited by 28 · see citing works
The uses of ultrasound in food processing
Mason, T. J., & Paniwnyk, L. (1996) · Advances in sonochemistry · doi:10.1016/s1569-2868(96)80007-6 · Cited by 8 · see citing works

Flagged first, then by citations

Sorted by citations

Ultrasound assisted extraction of food and natural products. Mechanisms, techniques, combinations, protocols and applications. A review
Chemat, F., Rombaut, N., Sicaire, A.-G., Meullemiestre, A., Fabiano-Tixier, A.-S., & Abert-Vian, M. (2017) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2016.06.035 · Cited by 3,278 · see citing works
Applications of ultrasound in food technology: Processing, preservation and extraction
Chemat, F., Zill-e-Huma, & Khan, M. K. (2010) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2010.11.023 · Cited by 2,541 · see citing works
Antioxidant Activity of Essential Oils
Amorati, R., Foti, M. C., & Valgimigli, L. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf403496k · Cited by 803 · see citing works
Advances in ultrasound assisted extraction of bioactive compounds from cash crops–A review
Wen, C., Zhang, J., Zhang, H., Dzah, C. S., Zandile, M., Duan, Y., Ma, H., & Luo, X. (2018) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2018.07.018 · Cited by 721 · see citing works
Intensification of extraction of natural products using ultrasonic irradiations—A review of current status
Shirsath, S. R., Sonawane, S. H., & Gogate, P. R. (2012) · Chemical Engineering and Processing - Process Intensification · doi:10.1016/j.cep.2012.01.003 · Cited by 634 · see citing works
Recent advances in the extraction of bioactive compounds with subcritical water: A review
Zhang, J., Wen, C., Zhang, H., Duan, Y., & Ma, H. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.11.018 · Cited by 490 · see citing works
Sample preparation techniques for the determination of trace residues and contaminants in foods
Ridgway, K., Lalljie, S. P. D., & Smith, R. M. (2007) · Journal of Chromatography A · doi:10.1016/j.chroma.2007.01.134 · Cited by 355 · see citing works
Chronic diseases, inflammation, and spices: how are they linked?
Kunnumakkara, A. B., Sailo, B. L., Banik, K., Harsha, C., Prasad, S., Gupta, S. C., Bharti, A. C., & Aggarwal, B. B. (2018) · Journal of Translational Medicine · doi:10.1186/s12967-018-1381-2 · Cited by 345 · see citing works
Simultaneous extraction of phenolic compounds of citrus peel extracts: Effect of ultrasound
Ma, Y., Chen, J., Liu, D., & Ye, X. (2008) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2008.04.012 · Cited by 295 · see citing works
High intensity ultrasound effects on meat brining
Cárcel, J. A., Benedito, J., Bon, J., & Mulet, A. (2007) · Meat Science · doi:10.1016/j.meatsci.2007.01.022 · Cited by 219 · see citing works
From plant phenols to novel bio-based polymers
Zhang, C., Xue, J., Yang, X., Ke, Y., Ou, R., Wang, Y., Madbouly, S. A., & Wang, Q. (2021) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2021.101473 · Cited by 217 · see citing works
Effects of different factors of ultrasound treatment on the extraction yield of the all-trans-β-carotene from citrus peels
Sun, Y., Liu, D., Chen, J., Ye, X., & Yu, D. (2010) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2010.05.014 · Cited by 212 · see citing works
Intensification of extraction of curcumin from Curcuma amada using ultrasound assisted approach: Effect of different operating parameters
Shirsath, S. R., Sable, S. S., Gaikwad, S. G., Sonawane, S. H., Saini, D. R., & Gogate, P. R. (2017) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2017.03.040 · Cited by 210 · see citing works
Molecular Targets of Nutraceuticals Derived from Dietary Spices: Potential Role in Suppression of Inflammation and Tumorigenesis
Aggarwal, B. B., Kuiken, M. E. V., Iyer, L. H., Harikumar, K. B., & Sung, B. (2009) · Experimental Biology and Medicine · doi:10.3181/0902-mr-78 · Cited by 204 · see citing works
The Immunomodulation and Anti-Inflammatory Effects of Garlic Organosulfur Compounds in Cancer Chemoprevention
Schäfer, G., & Kaschula, C. H. (2014) · Anti-Cancer Agents in Medicinal Chemistry · doi:10.2174/18715206113136660370 · Cited by 197 · see citing works
The Chemical Compositions of the Volatile Oils of Garlic (Allium sativum) and Wild Garlic (Allium vineale)
Satyal, P., Craft, J. D., Dosoky, N. S., & Setzer, W. N. (2017) · Foods · doi:10.3390/foods6080063 · Cited by 190 · see citing works
Anticancer activity of essential oils and their chemical components - a review.
Bayala, B., Bassolé, I. H. N., Scifo, R., Gnoula, C., Morel, L., Lobaccaro, J. A., & Simporè, J. (2014) · Europe PMC (PubMed Central) · Cited by 184 · see citing works
Characterization of selected Harbin red sausages on the basis of their flavour profiles using HS-SPME-GC/MS combined with electronic nose and electronic tongue
Yin, X., Lv, Y., Wen, R., Wang, Y., Chen, Q., & Kong, B. (2020) · Meat Science · doi:10.1016/j.meatsci.2020.108345 · Cited by 183 · see citing works
Encapsulation of garlic extract using complex coacervation with whey protein isolate and chitosan as wall materials followed by spray drying
Tavares, L., & Noreña, C. P. Z. (2018) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2018.10.052 · Cited by 166 · see citing works
A comparative study of various oil extraction techniques from plants
Danlami, J. M., Arsad, A., Zaini, M. A. A., & Sulaiman, H. (2014) · Reviews in Chemical Engineering · doi:10.1515/revce-2013-0038 · Cited by 159 · see citing works
A Review on Extraction Techniques and Its Future Applications in Industry
Geow, C. H., Tan, M. C., Yeap, S. P., & Chin, N. L. (2021) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.202000302 · Cited by 159 · see citing works
A review of advances and new developments in the analysis of biological volatile organic compounds
Zhang, Z., & Li, G. (2010) · Microchemical Journal · doi:10.1016/j.microc.2009.12.017 · Cited by 156 · see citing works
Ultrasound extraction of polysaccharides from mulberry leaves and their effect on enhancing antioxidant activity
Zhang, D., Wan, Y., Xu, J., Wu, G., Li, L., & Yao, X.-H. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.11.016 · Cited by 145 · see citing works
Stability and extraction of bioactive sulfur compounds from Allium genus processed by traditional and innovative technologies
Poojary, M. M., Putnik, P., Kovačević, D. B., Barba, F. J., Lorenzo, J. M., Dias, D. A., & Shpigelman, A. (2017) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2017.04.007 · Cited by 145 · see citing works
Potential therapeutic effects of functionally active compounds isolated from garlic
Yun, H., Ban, J. O., Park, K., Lee, C. K., Jeong, H., Han, S., & Hong, J. T. (2013) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.12.005 · Cited by 144 · see citing works
Patent Literature on Mosquito Repellent Inventions which Contain Plant Essential Oils - A Review
Pohlit, A. M., Lopes, N. P., Gama, R. A., Tadei, W. P., & de Andrade‐Neto, V. F. (2011) · Planta Medica · doi:10.1055/s-0030-1270723 · Cited by 142 · see citing works
Preparation, characterization, and biological activity of Cinnamomum cassia essential oil nano-emulsion
Liang, D., Feng, B., Li, N., Su, L., Wang, Z., Kong, F., & Bi, Y. (2022) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2022.106009 · Cited by 129 · see citing works
Extraction of ursolic acid from Ocimum sanctum by ultrasound: Process intensification and kinetic studies
Vetal, M. D., Lade, V. G., & Rathod, V. K. (2013) · Chemical Engineering and Processing - Process Intensification · doi:10.1016/j.cep.2013.01.011 · Cited by 125 · see citing works
Applications of Nonconventional Green Extraction Technologies in Process Industries: Challenges, Limitations and Perspectives
Fomo, G., Madzimbamuto, T. N., & Ojumu, T. V. (2020) · Sustainability · doi:10.3390/su12135244 · Cited by 121 · see citing works
Use of Power Ultrasound to Improve Extraction and Modify Phase Transitions in Food Processing
Chandrapala, J., Oliver, C. M., Kentish, S. E., & Ashokkumar, M. (2012) · Food Reviews International · doi:10.1080/87559129.2012.692140 · Cited by 120 · see citing works
Extraction of glycyrrhizic acid from licorice root using ultrasound: Process intensification studies
Charpe, T. W., & Rathod, V. K. (2012) · Chemical Engineering and Processing - Process Intensification · doi:10.1016/j.cep.2012.01.002 · Cited by 117 · see citing works
Extraction of Natural Products Using Microwaves as a Heat Source
Desai, M. A., Parikh, J. K., & Parikh, P. A. (2010) · Separation and Purification Reviews · doi:10.1080/15422111003662320 · Cited by 116 · see citing works
Ultrasound assisted maceration: An original procedure for direct aromatisation of olive oil with basil
Veillet, S., Tomao, V., & Chemat, F. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.05.005 · Cited by 111 · see citing works
Ultrasound bath-assisted extraction of essential oils from clove using central composite design
Tekin, K., Akalın, M. K., & Şeker, M. G. (2015) · Industrial Crops and Products · doi:10.1016/j.indcrop.2015.09.071 · Cited by 110 · see citing works
Red Cabbage (Brassica oleracea) Ameliorates Diabetic Nephropathy in Rats
Kataya, H. H., & Hamza, A. A. (2006) · Evidence-based Complementary and Alternative Medicine · doi:10.1093/ecam/nem029 · Cited by 110 · see citing works
Applications of in vivo and in vitro solid-phase microextraction techniques in plant analysis: A review
Zhu, F., Xu, J., Ke, Y., Huang, S., Zeng, F., Luan, T., & Ouyang, G. (2013) · Analytica Chimica Acta · doi:10.1016/j.aca.2013.05.016 · Cited by 104 · see citing works
Chemical and Biochemical Mechanisms Underlying the Cardioprotective Roles of Dietary Organopolysulfides
Tocmo, R., Liang, D., Lin, Y., & Huang, D. (2015) · Frontiers in Nutrition · doi:10.3389/fnut.2015.00001 · Cited by 102 · see citing works
Analytical methods for bioactive sulfur compounds in Allium: An integrated review and future directions
Ramírez, D. A., Locatelli, D. A., González, R. E., Cavagnaro, P. F., & Camargo, A. B. (2016) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2016.09.012 · Cited by 102 · see citing works
Evaluation of enzyme-assisted extraction on quality of garlic volatile oil
Sowbhagya, H. B., Purnima, K. T., Florence, S. P., Rao, A. G. A., & Srinivas, P. (2008) · Food Chemistry · doi:10.1016/j.foodchem.2008.08.011 · Cited by 99 · see citing works
Chemical composition of stinging nettle leaves obtained by different analytical approaches
Đurović, S. D., Pavlić, B., Šorgić, S., Popov, S., Savic, S. R., Petronijević, M., Radojković, M., Cvetanović, A. D., & Zeković, Z. P. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.02.019 · Cited by 92 · see citing works
Currents on Ultrasound‐Assisted Extraction for Sample Preparation and Spectroscopic Analytes Determination
Santos, D., Krug, F. J., Pereira, M. D. G., & Korn, M. (2006) · Applied Spectroscopy Reviews · doi:10.1080/05704920600620436 · Cited by 90 · see citing works
Selected Aspects Related to Medicinal and Aromatic Plants as Alternative Sources of Bioactive Compounds
Fierăscu, R. C., Fierăscu, I., Baroi, A. M., & Orțan, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22041521 · Cited by 88 · see citing works
Essential oil composition and antibacterial activity of different extracts of Allium roseum L., a North African endemic species
Najjaa, H., Neffati, M., Zouari, S., & Ammar, E. (2007) · Comptes Rendus Chimie · doi:10.1016/j.crci.2007.03.003 · Cited by 86 · see citing works
Vegetable Organosulfur Compounds and their Health Promoting Effects
Petropoulos, S. A., Gioia, F. D., & Ntatsi, G. (2017) · Current Pharmaceutical Design · doi:10.2174/1381612823666170111100531 · Cited by 88 · see citing works
Study on seafood volatile profile characteristics during storage and its potential use for freshness evaluation by headspace solid phase microextraction coupled with gas chromatography–mass spectrometry
Zhang, Z., Li, G., Luo, L. G., & Chen, G. (2009) · Analytica Chimica Acta · doi:10.1016/j.aca.2009.11.024 · Cited by 87 · see citing works
Detection of Volatile Metabolites of Garlic in Human Breast Milk
Scheffler, L., Sauermann, Y., Zeh, G., Hauf, K., Heinlein, A., Sharapa, C., & Buettner, A. (2016) · Metabolites · doi:10.3390/metabo6020018 · Cited by 81 · see citing works
Negative-pressure cavitation extraction for the determination of flavonoids in pigeon pea leaves by liquid chromatography–tandem mass spectrometry
Liu, W., Fu, Y., Zu, Y., Kong, Y., Zhang, L., Zu, B., & Efferth, T. (2009) · Journal of Chromatography A · doi:10.1016/j.chroma.2009.02.073 · Cited by 81 · see citing works
Nutritional Value, Chemical Characterization and Bulb Morphology of Greek Garlic Landraces
Petropoulos, S. A., Fernandes, Â. S. F., Ntatsi, G., Petrotos, K., Barros, L., & Ferreira, I. C. F. R. (2018) · Molecules · doi:10.3390/molecules23020319 · Cited by 81 · see citing works
Improvement of the bioaccessibility of bioactive compounds from Amazon fruits treated using high energy ultrasound
Carvalho, L. M. S., Lemos, M. C. M., Sanches, E. A., da Silva, L. S., Bezerra, J. D. A., Aguiar, J. P. L., Souza, F. D. C. D. A., Filho, E. G. A., & Campelo, P. H. (2020) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2020.105148 · Cited by 78 · see citing works
Ultrasound extraction of polysaccharides from guava leaves and their antioxidant and antiglycation activity
Luo, Y., Peng, B., Liu, Y., Wu, Y., & Wu, Z. (2018) · Process Biochemistry · doi:10.1016/j.procbio.2018.08.003 · Cited by 78 · see citing works
Flavor components, precursors, formation mechanisms, production and characterization methods: garlic, onion, and chili pepper flavors
Li, J., Dadmohammadi, Y., & Abbaspourrad, A. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1926906 · Cited by 76 · see citing works
A novel idea in food extraction field: Study of vacuum microwave hydrodiffusion technique for by-products extraction
Huma, Z., Vian, M. A., Elmaataoui, M., & Chemat, F. (2011) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2011.02.045 · Cited by 69 · see citing works
Bifunctional ultrasound assisted extraction and determination of Elettaria cardamomum Maton essential oil
Sereshti, H., Rohanifar, A., Bakhtiari, S., & Samadi, S. (2012) · Journal of Chromatography A · doi:10.1016/j.chroma.2012.03.061 · Cited by 67 · see citing works
Boiling enriches the linear polysulfides and the hydrogen sulfide-releasing activity of garlic
Tocmo, R., Wu, Y., Liang, D., Fogliano, V., & Huang, D. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.10.076 · Cited by 66 · see citing works
Encapsulation of tomato oleoresin with zein prepared from corn gluten meal
Xue, F., Li, C., Liu, Y., Zhu, X., Pan, S., & Wang, L. (2013) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2013.06.012 · Cited by 66 · see citing works
S‐Allyl cysteine in garlic ( Allium sativum ): Formation, biofunction, and resistance to food processing for value‐added product development
Yudhistira, B., Punthi, F., Lin, J., Sulaimana, A. S., Chang, C., & Hsieh, C. (2022) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12937 · Cited by 65 · see citing works
Effect of ultrasound‐assisted maceration on the quality of oil from the leaves of thyme Thymus vulgaris L.
Kowalski, R., & Wawrzykowski, J. (2009) · Flavour and Fragrance Journal · doi:10.1002/ffj.1918 · Cited by 62 · see citing works
Effect of ultrasonication on food bioactive compounds and their bio-accessibility: A review
Meena, L., Gowda, N. A. N., Sunil, C. K., Rawson, A., & Janghu, S. (2023) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2023.105899 · Cited by 57 · see citing works
Recent advances on supercritical fluid extraction of essential oils
Xu, L. (2011) · African Journal of Pharmacy and Pharmacology · doi:10.5897/ajpp11.228 · Cited by 56 · see citing works
Research Advances in Allelopathy of Volatile Organic Compounds (VOCs) of Plants
Xie, Y., Tian, L., Xu, H., & Yang, Y. (2021) · Horticulturae · doi:10.3390/horticulturae7090278 · Cited by 55 · see citing works
Valorization of food wastes by implementation of subcritical water extraction: A comprehensive review
Majeed, T., Shabir, I., Srivastava, S., Maqbool, N., Dar, A. H., Jan, K., Pandey, V. K., Shams, R., Bashir, I., Dash, K. K., et al. (2023) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2023.104316 · Cited by 55 · see citing works
Antibacterial Activity of Nanoparticles of Garlic (Allium sativum) Extract against Different Bacteria Such as Streptococcus mutans and Poryphormonas gingivalis
Gabriel, T., Vestine, A., Kim, K. D., Kwon, S. J., Sivanesan, I., & Chun, S. C. (2022) · Applied Sciences · doi:10.3390/app12073491 · Cited by 54 · see citing works
Application of response surface methodology to optimise ultrasonic‐assisted extraction of four chromones in Radix Saposhnikoviae
Li, W., Wang, Z., Sun, Y., Chen, L., Han, L., & Zheng, Y. (2011) · Phytochemical Analysis · doi:10.1002/pca.1282 · Cited by 54 · see citing works
A GC--MS Study of the Volatile Organic Composition of Straw and Oyster Mushrooms During Maturity and its Relation to Antioxidant Activity
Zhang, Z., Wu, W.-W., & Li, G.-K. (2008) · Journal of Chromatographic Science · doi:10.1093/chromsci/46.8.690 · Cited by 53 · see citing works
Synergistic Effect of Ultrasound and Three Phase Partitioning for the Extraction of Curcuminoids from Curcuma longa and its Bioactivity Profile
Patil, S. S., & Rathod, V. K. (2020) · Process Biochemistry · doi:10.1016/j.procbio.2020.02.031 · Cited by 52 · see citing works
Intensification of bioactive compounds extraction from Feijoa ( Feijoa sellowiana Berg.) leaves using ultrasonic waves
Poodi, Y., Bimakr, M., Ganjloo, A., & Zarringhalami, S. (2017) · Food and Bioproducts Processing · doi:10.1016/j.fbp.2017.12.004 · Cited by 52 · see citing works
Sulfur compounds identification and quantification from Allium spp. fresh leaves
Gîtin, L., Dinică, R. M., Bonciu, C., & Dumitraşcu, L. (2014) · Journal of Food and Drug Analysis · doi:10.1016/j.jfda.2014.04.002 · Cited by 51 · see citing works
Assessment of sensory metabolites distribution in 3 cactus Opuntia ficus-indica fruit cultivars using UV fingerprinting and GC/MS profiling techniques
Farag, M. A., Maamoun, A. A., Ehrlich, A., Fahmy, S., & Wessjohann, L. A. (2017) · LWT · doi:10.1016/j.lwt.2017.02.014 · Cited by 50 · see citing works
Impact of hydrodistillation and steam distillation on the yield and chemical composition of essential oils and their comparison with modern isolation techniques
Pheko-Ofitlhile, T., & Makhzoum, A. B. (2024) · Journal of Essential Oil Research · doi:10.1080/10412905.2024.2320350 · Cited by 49 · see citing works
Extraction of bioactive chemical compounds from the medicinal Asian plants by microwave irradiation
Asghari, J., Ondruschka, B., & Mazaheritehrani, M. (2011) · Journal of Medicinal Plants Research · doi:10.5897/jmpr.9000641 · Cited by 49 · see citing works
Evaluation of the ethanolic ultrasound-assisted extraction from clove (Syzygium aromaticum) leaves and chemical characterization of the extracts
Frohlich, P. C., Santos, K. A., Hasan, S. D. M., & da Silva, E. A. (2021) · Food Chemistry · doi:10.1016/j.foodchem.2021.131351 · Cited by 53 · see citing works
Recent advances in research on Allium plants: functional ingredients, physiological activities, and applications in agricultural and food sciences
Yan, J., Zhu, J., Liu, Y., Chen, X., Wang, W., Zhang, H., & Li, L. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2056132 · Cited by 48 · see citing works
Diallyl disulfide alleviates inflammatory osteolysis by suppressing osteoclastogenesis via NF‐κB–NFATc1 signal pathway
Yang, J., Tang, R., Jin, Y., Chen, Y., Li, X., Yu, T., & Fei, J. (2019) · The FASEB Journal · doi:10.1096/fj.201802172r · Cited by 48 · see citing works
Power ultrasonics for food processing
Mason, T. J., Chemat, F., & Ashokkumar, M. (2014) · Elsevier eBooks · doi:10.1016/b978-1-78242-028-6.00027-2 · Cited by 48 · see citing works
Application of response surface methodology for the optimization of supercritical carbon dioxide extraction and ultrasound-assisted extraction of Capparis spinosa seed oil
Ara, K. M., Karami, M., & Raofie, F. (2013) · The Journal of Supercritical Fluids · doi:10.1016/j.supflu.2013.10.016 · Cited by 44 · see citing works
Extraction, phytochemistry, nutritional, and therapeutical potentials of rice bran oil: A review
Sahini, M. G., & Mutegoa, E. (2023) · Phytomedicine Plus · doi:10.1016/j.phyplu.2023.100453 · Cited by 43 · see citing works
Biorefinery of turmeric ( Curcuma longa L.) using non-thermal and clean emerging technologies: an update on the curcumin recovery step
Neves, M. I. L., Strieder, M. M., Vardanega, R., Silva, E. K., & Meireles, M. A. A. (2019) · RSC Advances · doi:10.1039/c9ra08265d · Cited by 43 · see citing works
A single catalyst of aqueous CoIII for deodorization of mixture odor gases: A development and reaction pathway study at electro-scrubbing process
Muthuraman, G., & Moon, I. S. (2013) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2013.06.055 · Cited by 41 · see citing works
Diallyl disulfide, the antibacterial component of garlic essential oil, inhibits the toxicity of Bacillus cereus ATCC 14579 at sub-inhibitory concentrations
Jin, Z., Li, L., Zheng, Y., & An, P. (2021) · Food Control · doi:10.1016/j.foodcont.2021.108090 · Cited by 41 · see citing works
Ultrasound-assisted packed-bed extraction of hypericin from Hypericum perforatum L. and optimization by response surface methodology
Tahmasebi-Boldaji, R., Hatamipour, M. S., Khanahmadi, M., Sadeh, P., & Najafipour, I. (2019) · Ultrasonics Sonochemistry · doi:10.1016/j.ultsonch.2019.05.018 · Cited by 40 · see citing works
In silico study of garlic (Allium sativum L.)-derived compounds molecular interactions with α-glucosidase
Sadeghi, M., Moradi, M., Madanchi, H., & Johari, B. (2021) · In Silico Pharmacology · doi:10.1007/s40203-020-00072-9 · Cited by 38 · see citing works
Structural characteristic of polysaccharide isolated from Nostoc commune, and their potential as radical scavenging and antidiabetic activities
Wang, X., Yang, Z., Liu, Y., Wang, X., Zhang, H., Shang, R., Cidan, L., Wujin, C., Hao, B., & Wang, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-26802-x · Cited by 40 · see citing works
Microwave‐Accelerated Z‐Isomerization of (all‐E)‐Lycopene in Tomato Oleoresin and Enhancement of the Conversion by Vegetable Oils Containing Disulfide Compounds
Honda, M., Sato, H., Takehara, M., Inoue, Y., Kitamura, C., Takemura, R., Fukaya, T., Diono, W., Kanda, H., & Goto, M. (2018) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201800060 · Cited by 37 · see citing works
Comparison and Characterization of Garlic (Allium sativum L.) Bulbs Extracts and Their Effect on Mortality and Repellency of Tetranychus urticae Koch (Acari: Tetranychidae)
Ll., C. A. H., Gloria Eugenia López, P., & Torres, R. (2008) · Chilean journal of agricultural research · doi:10.4067/s0718-58392008000400001 · Cited by 37 · see citing works
Ultrasound assisted curcumin recovery from Curcuma aromatica: Understanding the effect of different operating parameters
Shirsath, S. R., Sable, S. S., Gaikwad, S. G., & Gogate, P. R. (2021) · Chemical Engineering and Processing - Process Intensification · doi:10.1016/j.cep.2021.108604 · Cited by 36 · see citing works
A brief review on the characteristics, extraction and potential industrial applications of citronella grass (Cymbopogon nardus) and lemongrass (Cymbopogon citratus) essential oils
Kumoro, A. C., Wardhani, D. H., Retnowati, D. S., & Haryani, K. (2021) · IOP Conference Series Materials Science and Engineering · doi:10.1088/1757-899x/1053/1/012118 · Cited by 35 · see citing works
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Zhao, B., Fu, Y., Wang, W., Zu, Y., Gu, C., Luo, M., & Efferth, T. (2011) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2011.05.003 · Cited by 35 · see citing works
A preliminary study of plant aroma profile characteristics by a combination sampling method coupled with GC–MS
Zhang, Z., & Li, G. (2006) · Microchemical Journal · doi:10.1016/j.microc.2006.09.003 · Cited by 35 · see citing works
Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC‐MS
Fu, Y., Zu, Y., Liu, W., Zhang, L., Tong, M., Efferth, T., Kong, Y., Hou, C., & Chen, L. (2008) · Journal of Separation Science · doi:10.1002/jssc.200700312 · Cited by 40 · see citing works
An Overview on Indications and Chemical Composition of Aromatic Waters (Hydrosols) as Functional Beverages in Persian Nutrition Culture and Folk Medicine for Hyperlipidemia and Cardiovascular Conditions
Hamedi, A., Moheimani, S. M., Sakhteman, A., Etemadfard, H., & Moein, M. (2017) · Journal of Evidence-Based Complementary & Alternative Medicine · doi:10.1177/2156587216686460 · Cited by 34 · see citing works
Separation of Oleoresin from Ginger Rhizome Powder Using Green Processing Technologies
Said, P. P., Arya, O. P., Pradhan, R. C., Singh, R. S., & Rai, B. N. (2014) · Journal of Food Process Engineering · doi:10.1111/jfpe.12127 · Cited by 34 · see citing works
Detection of Volatile Metabolites Derived from Garlic (Allium sativum) in Human Urine
Scheffler, L., Sauermann, Y., Heinlein, A., Sharapa, C., & Buettner, A. (2016) · Metabolites · doi:10.3390/metabo6040043 · Cited by 34 · see citing works
Effect of heat curing on antifungal activities of anise oil and garlic oil against Aspergillus niger on rubberwood
Matan, N., Matan, N., & Ketsa, S. (2012) · International Biodeterioration & Biodegradation · doi:10.1016/j.ibiod.2012.03.012 · Cited by 33 · see citing works
Diallyl Trisulfide, the Antifungal Component of Garlic Essential Oil and the Bioactivity of Its Nanoemulsions Formed by Spontaneous Emulsification
Gong, X., Su, X., & Liu, H. (2021) · Molecules · doi:10.3390/molecules26237186 · Cited by 33 · see citing works
Effect of Processing Conditions on the Organosulfides of Shallot (Allium cepa L. Aggregatum Group)
Tocmo, R., Lin, Y., & Huang, D. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf500739n · Cited by 33 · see citing works
SAMPLE PREPARATION FOR TRACE ANALYSIS BY CHROMATOGRAPHIC METHODS
Olariu, R. I., Vione, D. V., Grinberg, N., & Arsene, C. (2010) · Journal of Liquid Chromatography & Related Technologies · doi:10.1080/10826076.2010.484371 · Cited by 32 · see citing works
Influence of drying technologies on the aroma of Sicilian red garlic
Condurso, C., Cincotta, F., Tripodi, G., Merlino, M. V., & Verzera, A. (2019) · LWT · doi:10.1016/j.lwt.2019.01.026 · Cited by 31 · see citing works
Health Benefits of Organosulfur Compounds
Walag, A. M. P., Ahmed, O., Jeevanandam, J., Akram, M., Ephraim-Emmanuel, B. C., Egbuna, C., Semwal, P., Iqbal, M., Hassan, S., & Uba, J. O. (2020) · Springer eBooks · doi:10.1007/978-3-030-42319-3_21 · Cited by 31 · see citing works
Comparison of volatile compounds in different parts of fresh Amomum villosum Lour. from different geographical areas using cryogenic grinding combined HS–SPME–GC–MS
Chen, L.-X., Lai, Y., Zhang, W.-X., Cai, J., Hu, H., Wang, Y., Zhao, J., & Li, S. (2020) · Chinese Medicine · doi:10.1186/s13020-020-00377-z · Cited by 31 · see citing works
Variability in Bulb Organosulfur Compounds, Sugars, Phenolics, and Pyruvate among Greek Garlic Genotypes: Association with Antioxidant Properties
Avgeri, I., Ζέλιου, Κ., Petropoulos, S. A., Bebeli, P. J., Papasotiropoulos, V., & Lamari, F. N. (2020) · Antioxidants · doi:10.3390/antiox9100967 · Cited by 31 · see citing works

Comparison of Volatile Compounds Profile and Antioxydant Activity of Allium sativum Essential Oils Extracted using Hydrodistillation, Ultrasound- Assisted and Sono-Hydrodistillation Processes
Boubechiche, Z., Chihib, N., Jama, C., & Hellal, A. (2017) · Indian Journal of Pharmaceutical Education and Research · doi:10.5530/ijper.51.3s.30 · Cited by 20 · see citing works
Molecular Distillation Purification and Analysis of Volatile Components of Garlic Oil Extracted by Supercritical Carbon Dioxide Extraction
Bi-wen, C. (2010) · Food Science
Solid-phase microextraction–gas chromatographic–mass spectrometric analysis of garlic oil obtained by hydrodistillation
Calvo-Gómez, O., Morales-López, J., & López, M. G. (2004) · Journal of Chromatography A · doi:10.1016/j.chroma.2004.02.072 · Cited by 107 · see citing works
Extraction of Garlic Oil using Microwave Ultrasonic Assisted Extraction Method
Putra, A. F. P., Nabila, N. N., & Salsabila, S. P. (2019) · International Conference on Industrial Technology · doi:10.5220/0009445402330236 · Cited by 1 · see citing works
Comparative Analysis of Volatile Oil Extracted from Asarum sieboldii Miq. by Steam Distillation and Ultrasound-assisted Extraction
Tian-zhi, O. (2011) · Food Science · Cited by 2 · see citing works

Authors: Kimbaris, A. C., Siatis, N. G., Daferera, D. J., Tarantilis, P. A., Pappas, C. S., & Polissiou, M. G.
Affiliations: Agricultural University of Athens (GR)
Corresponding author: Polissiou, Moschos G.
ORCID: Kimbaris, Athanasios C.
Daferera, Dimitra J.
Polissiou, Moschos G.
Venue: Ultrasonics Sonochemistry
Publisher: Elsevier BV
Published: 2006-01
Volume: 13
Issue: 1
Pages: 54-60
ISSN: 1350-4177 (ISSN-L)
DOI: 10.1016/j.ultsonch.2004.12.003
OpenAlex: W2005127689
Cited by: 281
References: 32
Citations by year: 2026: 5 · 2025: 12 · 2024: 10 · 2023: 14 · 2022: 18 · 2021: 28 · 2020: 21 · 2019: 20 · 2018: 13 · 2017: 18 · 2016: 13 · 2015: 11 · 2014: 20 · 2013: 13 · 2012: 8
FWCI: 8.79
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Ultrasonics Sonochemistry (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
Keywords: garlic, essential oils, aroma compounds, simultaneous distillation extraction, microwave-assisted hydrodistillation, ultrasound-assisted extraction, sulfur compounds, thermal sensitivity
MeSH terms: Chemical Fractionation, Garlic, Hydrocarbons, Aromatic, Plant Extracts, Sonication

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Comparison of distillation and ultrasound-assisted extraction methods for the isolation of sensitive aroma compounds from garlic (Allium sativum)

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks