The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics.
Abstract
Resistance to antimicrobials, in particular that mediated by extended spectrum β-lactamases (ESBL) and AmpC β-lactamases are frequently reported in bacteria causing canine disease as well as in commensal bacteria, which could be a potential health risk for humans they come into contact with. This cross-sectional study aimed to estimate the prevalence and investigate the molecular characteristics of ESBL and plasmid encoded AmpC (pAmpC)-producing E. coli in the mainland UK vet-visiting canine population and, using responses from detailed questionnaires identify factors associated with their carriage. Faecal samples were cultured for antimicrobial resistant (AMR), ESBL and pAmpC-producing E. coli. A subset of ESBL and pAmpC-producing isolates were subjected to multi-locus sequence typing and DNA microarray analyses. Multivariable logistic regression analysis was used to construct models to identify risk factors associated with multidrug resistant (MDR, resistance to three or more antimicrobial classes), fluoroquinolone resistant, ESBL and AmpC-producing E. coli. AMR E.coli were isolated from 44.8% (n=260) of samples, with 1.9% and 7.1% of samples carrying ESBL and pAmpC-producing E. coli, respectively. MDR E. coli were identified in 18.3% of samples. Recent use of antimicrobials and being fed raw poultry were both identified as risk factors in the outcomes investigated. A number of virulence and resistance genes were identified, including genes associated with extra-intestinal and enteropathogenic E. coli genotypes. Considering the close contact that people have with dogs, the high levels of AMR E. coli in canine faeces may be a potential reservoir of AMR bacteria or resistance determinants.
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“or for multi‐drug‐resistant E. coli (Groat et al. 2016, Wedley et al. 2017).”
From Raw diets for dogs and cats: a review, with particular reference to microbiological hazards. (2019) · cites this paper as Wedley et al. 2017
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“Another UK cross‐sectional study reported a strong association between feeding raw poultry and faecal ESBL E. coli among veterinary‐visiting dogs (Wedley et al. 2017).”
From Raw diets for dogs and cats: a review, with particular reference to microbiological hazards. (2019) · cites this paper as Wedley et al. 2017
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Cites
Kaper, J. B., Nataro, J. P., & Mobley, H. L. T. (2004) · Nature Reviews Microbiology · doi:10.1038/nrmicro818 · Cited by 5,583 · cited 2×
“Dogs often eat faeces of livestock, which are carriers of EHEC, furthermore a previous study found coprophagy to be a risk factor for antimicrobial resistance in canine faecal samples (Leite-Martins et al., 2014).”
BackgroundSex and virulence in Escherichia coli: an evolutionary perspective
Wirth, T., Falush, D., Lan, R., Colles, F., Mensa, P., Wieler, L. H., Karch, H., Reeves, P. R., Maiden, M. C. J., Ochman, H., et al. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05172.x · Cited by 2,025
Detection of Plasmid-Mediated AmpC β-Lactamase Genes in Clinical Isolates by Using Multiplex PCR
Pérez-Pérez, F. J., & Hanson, N. D. (2002) · Journal of Clinical Microbiology · doi:10.1128/jcm.40.6.2153-2162.2002 · Cited by 1,512
Epidemiology of resistance to antibiotics Links between animals and humans
van den Bogaard, A. (2000) · International Journal of Antimicrobial Agents · doi:10.1016/s0924-8579(00)00145-x · Cited by 1,066
Partitioning Variation in Multilevel Models
Goldstein, H., Browne, W., & Rasbash, J. (2002) · Understanding Statistics · doi:10.1207/s15328031us0104_02 · Cited by 874 · cited 1×
“To determine the intraclass correlation coefficient (the measure of clustering of an outcome within practices), the latent variable approach was used (Goldstein et al., 2002) with equation 1 below.”
MethodBSAC standardized disc susceptibility testing method (version 7)
Andrews, J. M., & Testing, F. T. B. W. P. O. S. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn194 · Cited by 734
Extended-Spectrum B-Lactamase Genes of Escherichia coli in Chicken Meat and Humans, the Netherlands
Overdevest, I. (2011) · Emerging Infectious Diseases · doi:10.3201/eid1707.110209 · Cited by 570
Extraintestinal pathogenic Escherichia coli : “The other bad E coli ”
Johnson, J. R., & Russo, T. A. (2002) · Journal of Laboratory and Clinical Medicine · doi:10.1067/mlc.2002.121550 · Cited by 423
Phylogenetic Distribution of Extraintestinal Virulence‐Associated Traits in Escherichia coli
Johnson, J. R., Delavari, P., Kuskowski, M., & Stell, A. L. (2001) · The Journal of Infectious Diseases · doi:10.1086/317656 · Cited by 400
Boyd, D. A., Tyler, S. D., Christianson, S., McGeer, A., Muller, M. P., Willey, B. M., Bryce, E., Gardam, M. A., Nordmann, P., & Mulvey, M. R. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.10.3758-3764.2004 · Cited by 389
Research works printed but not linked: 1
- Biological, H.E.P.O, 2011, Scientific Opinion on the public health risks of bacterial strains producing extended-spectrum β-lactamases and/or AmpC β-lactamases in food and food-producing animals, EFSA J., 9
Cited by
Raw diets for dogs and cats: a review, with particular reference to microbiological hazards.
Davies, R. H., Lawes, J. R., & Wales, A. D. (2019) · Journal of Small Animal Practice · doi:10.1111/jsap.13000 · Cited by 195
“Another UK cross-sectional study reported a strong association between feeding raw poultry and faecal ESBL E. coli among veterinary-visiting dogs (Wedley et al. 2017).”
BackgroundBaede, V. O., Broens, E. M., Spaninks, M. P., Timmerman, A. J., Graveland, H., Wagenaar, J. A., Duim, B., & Hordijk, J. (2017) · PLOS ONE · doi:10.1371/journal.pone.0187239 · Cited by 70
Metadata
- Authors
- Wedley, A. L., Dawson, S., Maddox, T. W., Coyne, K. P., Pinchbeck, G. L., Clegg, P., Nuttall, T., Kirchner, M., & Williams, N. J.
- Venue
- Veterinary Microbiology
- Publisher
- Elsevier BV
- Published
- 2017-02
- Volume
- 199
- Pages
- 23-30
- ISSN
- 0378-1135
- Cited by
- 91
- References
- 46
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Funders
- Department for Environment, Food and Rural Affairs (Defra)
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- Wedley, A. L., Dawson, S., Maddox, T. W., Coyne, K. P., Pinchbeck, G. L., Clegg, P., Nuttall, T., Kirchner, M., & Williams, N. J. (2017). Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics. Veterinary Microbiology. https://doi.org/10.1016/j.vetmic.2016.11.017
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
