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Low- and high-risk human papillomavirus E7 proteins regulate p130 differently
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“only high-risk E7s can target all three of the pRB family proteins for degradation”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [136]
In the citing paper
“it has been suggested that the inability of low-risk HPV types to drive robust basal cell proliferation is because they can only efficiently induce the degradation of p130, which regulates cell cycle entry in the upper epithelial layers, but they cannot target p107 and p105”
From The Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 Oncoproteins in the Orchestration of Carcinogenesis (2021) · cites this paper as [136]
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Citations
Cites
The E2F transcriptional network: old acquaintances with new faces
Dimova, D. K., & Dyson, N. J. (2005) · Oncogene · doi:10.1038/sj.onc.1208612 · Cited by 715
Pocket proteins and cell cycle control
Cobrinik, D. (2005) · Oncogene · doi:10.1038/sj.onc.1208619 · Cited by 601
Research works printed but not linked: 50
- Armstrong, 1992, Mutagenesis of human papillomavirus types 6 and 16 E7 open reading frames alters the electrophoretic mobility of the expressed proteins, J. Gen. Virol., 73, 1275, 10.1099/0022-1317-73-5-1275 · DOI
- Baldwin, 2006, Human papillomavirus E7 oncoprotein dysregulates steroid receptor coactivator 1 localization and function, J. Virol., 80, 6669, 10.1128/JVI.02497-05 · DOI
- Banerjee, 2006, Conditionally activated E7 proteins of high-risk and low-risk human papillomaviruses induce S phase in postmitotic, differentiated human keratinocytes, J. Virol., 80, 6517, 10.1128/JVI.02499-05 · DOI
- Cam, 2003, Emerging roles for E2F: beyond the G1/S transition and DNA replication, Cancer Cell, 3, 311, 10.1016/S1535-6108(03)00080-1 · DOI
- Chestukhin, 2002, Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism, Mol. Cell. Biol., 22, 453, 10.1128/MCB.22.2.453-468.2002 · DOI
- Ciccolini, 1994, Functional studies of E7 proteins from different HPV types, Oncogene, 9, 2633
- Classon, 2001, p107 and p130: versatile proteins with interesting pockets, Exp. Cell Res., 264, 135, 10.1006/excr.2000.5135 · DOI
- Claudio, 2002, The retinoblastoma family: twins or distant cousins?, Genome Biol., 3, 10.1186/gb-2002-3-9-reviews3012 · DOI
- Collins, 2005, Interactions with pocket proteins contribute to the role of human papillomavirus type 16 E7 in the papillomavirus life cycle, J. Virol., 79, 14769, 10.1128/JVI.79.23.14769-14780.2005 · DOI
- DeCaprio, 1992, The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression, Proc. Natl. Acad. Sci. U. S. A., 89, 1795, 10.1073/pnas.89.5.1795 · DOI
- Demers, 1994, Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7, Proc. Natl. Acad. Sci. U. S. A., 91, 4382, 10.1073/pnas.91.10.4382 · DOI · Paper page
- Deshaies, 1999, SCF and Cullin/Ring H2-based ubiquitin ligases, Annu. Rev. Cell Dev. Biol., 15, 435, 10.1146/annurev.cellbio.15.1.435 · DOI
- Drain, 2002, Determinants of cervical cancer rates in developing countries, Intl. J. of Cancer, 100, 199, 10.1002/ijc.10453 · DOI
- Dyson, 1989, The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product, Science, 243, 934, 10.1126/science.2537532 · DOI · Paper page
- Flores, 2000, The human papillomavirus type 16 E7 oncogene is required for the productive stage of the viral life cycle, J. Virol., 74, 6622, 10.1128/JVI.74.14.6622-6631.2000 · DOI
- Gage, 1990, The E7 proteins of the nononcogenic human papillomavirus type 6b (HPV-6b) and of the oncogenic HPV-16 differ in retinoblastoma protein binding and other properties, J. Virol., 64, 723, 10.1128/jvi.64.2.723-730.1990 · DOI · Paper page
- Genovese, 2008, Casein kinase II motif-dependent phosphorylation of human papillomavirus E7 protein promotes p130 degradation and S-phase induction in differentiated human keratinocytes, J. Virol., 82, 4862, 10.1128/JVI.01202-07 · DOI
- Gonzalez, 2001, Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7, J. Virol., 75, 7583, 10.1128/JVI.75.16.7583-7591.2001 · DOI · Paper page
- Guccione, 2002, Comparative analysis of the intracellular location of the high- and low-risk human papillomavirus oncoproteins, Virology, 293, 20, 10.1006/viro.2001.1290 · DOI · Paper page
- Hebner, 2006, Human papillomaviruses: basic mechanisms of pathogenesis and oncogenicity, Rev. Med. Virol., 16, 83, 10.1002/rmv.488 · DOI
- Helin, 1993, Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation, Genes Dev., 7, 1850, 10.1101/gad.7.10.1850 · DOI
- Huh, 2005, Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600, Proc. Natl. Acad. Sci. U. S. A., 102, 11492, 10.1073/pnas.0505337102 · DOI · Paper page
- Huh, 2007, Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor, J. Virol., 81, 9737, 10.1128/JVI.00881-07 · DOI · Paper page
- Jewers, 1992, Regions of human papillomavirus type 16 E7 oncoprotein required for immortalization of human keratinocytes, J. Virol., 66, 1329, 10.1128/jvi.66.3.1329-1335.1992 · DOI
- Kehn, 2005, The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation, Oncogene, 24, 525, 10.1038/sj.onc.1208105 · DOI
- Knapp, 2009, Identification of the nuclear localization and export signals of high risk HPV16 E7 oncoprotein, Virology, 383, 60, 10.1016/j.virol.2008.09.037 · DOI
- Kubo, 1999, The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4, Clin. Cancer Res., 5, 4279
- Litovchick, 2004, Glycogen synthase kinase 3 phosphorylates RBL2/p130 during quiescence, Mol. Cell. Biol., 24, 8970, 10.1128/MCB.24.20.8970-8980.2004 · DOI
- Longworth, 2004, Pathogenesis of human papillomaviruses in differentiating epithelia, Microbiol. Mol. Biol. Rev., 68, 362, 10.1128/MMBR.68.2.362-372.2004 · DOI
- Ludwig, 1999, Diminished rev-mediated stimulation of human immunodeficiency virus type 1 protein synthesis is a hallmark of human astrocytes, J. Virol., 73, 8279, 10.1128/JVI.73.10.8279-8289.1999 · DOI
- McLaughlin-Drubin, 2005, The role of the human papillomavirus type 18 E7 oncoprotein during the complete viral life cycle, Virology, 338, 61, 10.1016/j.virol.2005.04.036 · DOI
- Meijer, 1997, Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5, Eur. J. Biochem., 243, 527, 10.1111/j.1432-1033.1997.t01-2-00527.x · DOI · Paper page
- Munger, 2001, Biological activities and molecular targets of the human papillomavirus E7 oncoprotein, Oncogene, 20, 7888, 10.1038/sj.onc.1204860 · DOI
- Nguyen, 2007, Human papillomavirus type 16 E7 oncoprotein associates with the centrosomal component gamma-tubulin, J. Virol., 81, 13533, 10.1128/JVI.01669-07 · DOI · Paper page
- Oh, 2004, Roles of the E6 and E7 proteins in the life cycle of low-risk human papillomavirus type 11, J. Virol., 78, 2620, 10.1128/JVI.78.5.2620-2626.2004 · DOI
- Sedlacek, 2001, Mechanisms of action of flavopiridol, Crit. Rev. Oncol. Hematol., 38, 139, 10.1016/S1040-8428(00)00124-4 · DOI
- Shirodkar, 1992, The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner, Cell, 68, 157, 10.1016/0092-8674(92)90214-W · DOI
- Smith-McCune, 1999, Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130, Proc. Natl. Acad. Sci. U. S. A., 96, 6999, 10.1073/pnas.96.12.6999 · DOI · Paper page
- Smotkin, 1987, The major human papillomavirus protein in cervical cancers is a cytoplasmic phosphoprotein, J. Virol., 61, 1686, 10.1128/jvi.61.5.1686-1689.1987 · DOI · Paper page
- Snijders, 2006, HPV-mediated cervical carcinogenesis: concepts and clinical implications, J. Pathol., 208, 152, 10.1002/path.1866 · DOI
- Srinivasan, 1997, The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain, Mol. Cell. Biol., 17, 4761, 10.1128/MCB.17.8.4761 · DOI · Paper page
- Stubdal, 1997, Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen, Mol. Cell. Biol., 17, 4979, 10.1128/MCB.17.9.4979 · DOI
- Tedesco, 2002, The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCFSkp2, Genes Dev., 16, 2946, 10.1101/gad.1011202 · DOI
- von Mikecz, 2006, The nuclear ubiquitin–proteasome system, J. Cell Sci., 119, 1977, 10.1242/jcs.03008 · DOI
- Wang, 2009, Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes, Genes Dev., 23, 181, 10.1101/gad.1735109 · DOI
- Westbrook, 2002, E7 abolishes raf-induced arrest via mislocalization of p21(Cip1), Mol. Cell. Biol., 22, 7041, 10.1128/MCB.22.20.7041-7052.2002 · DOI
- Wolff, 1997, Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA, Chem. Biol., 4, 139, 10.1016/S1074-5521(97)90257-X · DOI
- Zhang, 2006, The E7 proteins of low- and high-risk human papillomaviruses share the ability to target the pRB family member p130 for degradation, Proc. Natl. Acad. Sci. U. S. A., 103, 437, 10.1073/pnas.0510012103 · DOI · Paper page
- zur Hausen, 2000, Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis, J. Natl. Cancer Inst., 92, 690, 10.1093/jnci/92.9.690 · DOI
- zur Hausen, 2002, Papillomaviruses and cancer: from basic studies to clinical application, Nat. Rev. Cancer, 2, 342, 10.1038/nrc798 · DOI
Cited by
Basukala, O., & Banks, L. (2021) · Viruses · doi:10.3390/v13101892 · Cited by 137
Metadata
- Authors
- Barrow-Laing, L., Chen, W., & Roman, A.
- Venue
- Virology
- Publisher
- Elsevier BV
- Published
- 2010-05
- Volume
- 400
- Issue
- 2
- Pages
- 233-239
- ISSN
- 0042-6822
- PMC
- PMC2861914
- Cited by
- 39
- References
- 2
- Language
- en
- Licence
- Funders
- National Institutes of Health (R01 AI49294)
- Indiana University School of Medicine
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