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Cited by 48Spine and Intervertebral Disc PathologyMusculoskeletal pain and rehabilitationCervical and Thoracic Myelopathy

Extent of preoperative depression is associated with return to work after lumbar fusion for spondylolisthesis

Parker, Scott L., Godil, Saniya S., Zuckerman, Scott L., Mendenhall, Stephen K., Devin, Clinton J., McGirt, Matthew J.·2015·World Neurosurgery
DOI 10.1016/j.wneu.2014.12.018
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Abstract

Background The ability to understand factors associated with an increased duration of missed work postoperatively could be used to more effectively select patients with the greatest opportunity for a successful outcome. We set out to determine the effect of preoperative depression on postoperative return to work in patients undergoing transforaminal lumbar interbody fusion (TLIF) for degenerative spondylolisthesis.Methods Fifty-eight patients undergoing TLIF for symptomatic grade I degenerative lumbar spondylolisthesis were included in this analysis. Patient demographics, clinical presentation, indications for surgery, radiologic studies, and operative variables were assessed for each case. Patient-assessed outcome measures were obtained prospectively at baseline and 2 years postoperatively. To understand the factors associated with prolonged return to work, univariate linear regression analysis and stepwise multivariate Cox proportional hazards model was used.Results All patient-reported outcomes assessed were significantly improved 2 years after TLIF (P < 0.001). Of the 32 patients working preoperatively, 26 (81%) returned to work postoperatively. Median time to return to work was 56 days (range, 10-150 days). Independent of patient age; preoperative pain, disability, and quality of life; and extent of postoperative improvement, increased preoperative Zung depression score remained associated with prolonged return to work (P = 0.02).Conclusions Independent of postoperative improvement in pain, disability, and quality of life, the extent of preoperative depression was an independent predictor of time to return to work in patients undergoing TLIF for spondylolisthesis, suggesting that regardless of how successful TLIF surgery may be at improving a patient's pain, disability, or quality of life, greater depression will delay or prohibit their ability to return to work postoperatively.

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  • Evidence suggests that ignoring pain is associated with both increased and decreased pain interference.

    “Evidence suggests an association between ignoring pain and both increased and decreased pain interference 281, 288–290.”

    From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [288]

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Authors
Parker, S. L., Godil, S. S., Zuckerman, S. L., Mendenhall, S. K., Devin, C. J., & McGirt, M. J.
Affiliations
  • Vanderbilt University Medical Center (US)
  • Carolina Neurosurgery and Spine Associates (US)
ORCID
Venue
World Neurosurgery
Publisher
Elsevier BV
Published
2015-04
Volume
83
Issue
4
Pages
608-613
ISSN
1878-8750 (ISSN-L)
DOI
10.1016/j.wneu.2014.12.018
OpenAlex
W2017892116
Cited by
46
References
55
Citations by year
2026: 3 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 7 · 2018: 7 · 2017: 4 · 2016: 5 · 2015: 4
FWCI
3.22
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • World Neurosurgery (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Surgery › Cervical and Thoracic Myelopathy
Keywords
preoperative depression, return to work, transforaminal lumbar interbody fusion, degenerative spondylolisthesis, Zung Self-Rating Depression Scale, postoperative recovery, patient-reported outcomes, work disability
MeSH terms
Adolescent, Adult, Aged, Depression, Disability Evaluation, Female, Humans, Lumbar Vertebrae, Male, Middle Aged, Prospective Studies, Quality of Life, Spinal Fusion, Spondylolisthesis, Treatment Outcome, Kaplan-Meier Estimate, Young Adult, Return to Work

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