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Performance of Glomerular Filtration Rate Estimating Equations Before and After Bariatric Surgery
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![Figure 2 Median bias of estimating equations pre- and postsurgery. Median bias (estimated glomerular filtration rate [eGFR] − measured GFR) and 95% CIs are shown presurgery overall and then approximately 6 months postsurgery, overall and then stratified by weight (Wt) loss (above and below median 6-month weight loss). Abbreviations: BSA, body surface area; eGFRcr, eGFR based on creatinine level; eGFRcr-cys, eGFR based on creatinine and cystatin C levels; eGFRcys, eGFR based on cystatin C level.](/paper-figures/c6514f840a504421a7d642c1f72ffc1d/performance-of-glomerular-filtration-rate-estimating-equations-before-and-after-figure-2.jpg)
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“However, in patients receiving GLP-1 receptor agonists, serial measurements of creatinine-based eGFR may be confounded by an effect of these drugs to reduce muscle mass,89 and the resulting decline in serum creatinine may imply an improvement in kidney function that has not taken place.53,56”
From Interplay of Chronic Kidney Disease and the Effects of Tirzepatide in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity (2025) · cites this paper as [53]
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Estimating glomerular filtration rate from serum creatinine and cystatin C
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Sorted by citations
Long-term kidney outcomes of semaglutide in obesity and cardiovascular disease in the SELECT trial
Colhoun, H. M., Lingvay, I., Brown, P. M., Deanfield, J., Brown-Frandsen, K., Kahn, S. E., Plutzky, J., Node, K., Parkhomenko, A., Rydén, L., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03015-5 · Cited by 238
Cortinovis, M., Perico, N., Ruggenenti, P., Remuzzi, A., & Remuzzi, G. (2022) · Nature Reviews Nephrology · doi:10.1038/s41581-022-00559-y · Cited by 214
Packer, M., Zile, M. R., Kramer, C. M., Murakami, M., Ou, Y., & Borlaug, B. A. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2025.03.009 · Cited by 49
Metadata
- Authors
- Chang, A. R., George, J., Levey, A. S., Coresh, J., Grams, M. E., & Inker, L. A.
- Venue
- Kidney Medicine
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 2
- Issue
- 6
- Pages
- 699-706.e1
- ISSN
- 2590-0595
- PMC
- PMC7729215
- Cited by
- 38
- References
- 1
- Language
- en
- Licence
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases
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