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Ubiquitination is required for the initial removal of paternal organelles in C. elegans
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After this reaction, the probe can be fixed and remains in the mitochondria independent of subsequent alterations in mitochondrial function or mitochondrial membrane potential.
“After this reaction, the probe can be fixed and remains in the mitochondria independent of subsequent alterations in mitochondrial function or mitochondrial membrane potential [1115,1117,1118].”
From Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1 (2021) · cites this paper as [1117]
The Materials and Methods section (‘Mitotracker staining’; page unavailable) says the authors labeled males with MitoTracker Red CMXRos, but does not say the labeled probe can be fixed or remains in mitochondria after changes in function or membrane potential. Searches for fixation and membrane-potential dependence found no passage addressing those properties. (LLM, conf=0.74)
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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
Tanaka, A., Cleland, M. M., Xu, S., Narendra, D. P., Suen, D.-F., Karbowski, M., & Youle, R. J. (2010) · Journal of Cell Biology · doi:10.1083/jcb.201007013 · Cited by 1,369
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
Ju, J.-S., Fuentealba, R. A., Miller, S. E., Jackson, E., Piwnica-Worms, D., Baloh, R. H., & Weihl, C. C. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200908115 · Cited by 494
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Research works printed but not linked: 47
- Al Rawi, 2011, Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission, Science, 334, 1144, 10.1126/science.1211878 · DOI · Paper page
- Bjorkoy, 2005, p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death, J. Cell Biol., 171, 603, 10.1083/jcb.200507002 · DOI · Paper page
- Boyd, 2011, Time-lapse microscopy of early embryogenesis in Caenorhabditis elegans, J. Vis. Exp., 54
- Brenner, 1974, The genetics of Caenorhabditis elegans, Genetics, 77, 71, 10.1093/genetics/77.1.71 · DOI
- Chan, 2012, Eliminating mitochondrial DNA from sperm, Dev. Cell, 22, 469, 10.1016/j.devcel.2012.02.008 · DOI
- Chan, 2011, Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy, Hum. Mol. Genet., 20, 1726, 10.1093/hmg/ddr048 · DOI · Paper page
- Christensen, 2007, E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages, Nat. Struct. Mol. Biol., 14, 941, 10.1038/nsmb1295 · DOI · Paper page
- DeLuca, 2012, Barriers to male transmission of mitochondrial DNA in sperm development, Dev. Cell, 22, 660, 10.1016/j.devcel.2011.12.021 · DOI
- Djeddi, 2015, Sperm-inherited organelle clearance in C. elegans relies on LC3-dependent autophagosome targeting to the pericentrosomal area, Development, 142, 1705, 10.1242/dev.117879 · DOI · Paper page
- Dove, 2017, Two functionally distinct E2/E3 pairs coordinate sequential ubiquitination of a common substrate in, Proc. Natl. Acad. Sci. U. S. A., 114, E6576, 10.1073/pnas.1705060114 · DOI
- Dove, 2016, Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms, EMBO Rep., 17, 1221, 10.15252/embr.201642641 · DOI
- Gatica, 2018, Cargo recognition and degradation by selective autophagy, Nat. Cell Biol., 20, 233, 10.1038/s41556-018-0037-z · DOI · Paper page
- Gegg, 2011, PINK1-parkin-dependent mitophagy involves ubiquitination of mitofusins 1 and 2: implications for Parkinson disease pathogenesis, Autophagy, 7, 243, 10.4161/auto.7.2.14332 · DOI
- Geisler, 2010, PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1, Nat. Cell Biol., 12, 119, 10.1038/ncb2012 · DOI · Paper page
- Hajjar, 2014, Dual roles for ubiquitination in the processing of sperm organelles after fertilization, J. BMC Develop. Biol., 14, 6, 10.1186/1471-213X-14-6 · DOI
- Husnjak, 2008, Proteasome subunit Rpn13 is a novel ubiquitin receptor, Nature, 453, 481, 10.1038/nature06926 · DOI
- Hutchison, 1974, Maternal inheritance of mammalian mitochondrial DNA, Nature, 251, 536, 10.1038/251536a0 · DOI
- Huynh, 2007, LAMP proteins are required for fusion of lysosomes with phagosomes, EMBO J., 26, 313, 10.1038/sj.emboj.7601511 · DOI · Paper page
- Kamath, 2003, Systematic functional analysis of the Caenorhabditis elegans genome using RNAi, Nature, 421, 231, 10.1038/nature01278 · DOI
- Kim, 2008, Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes, Proc. Natl. Acad. Sci. U. S. A., 105, 20567, 10.1073/pnas.0810611105 · DOI
- Kirkin, 2009, A role for NBR1 in autophagosomal degradation of ubiquitinated substrates, Mol. Cell, 33, 505, 10.1016/j.molcel.2009.01.020 · DOI · Paper page
- Liu, 2012, Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells, Nat. Cell Biol., 14, 177, 10.1038/ncb2422 · DOI
- López-Mosqueda, 2014, Deciphering functions of branched ubiquitin chains, J. Cell., 157, 767
- Matsumoto, 2011, Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins, Mol. Cell, 44, 279, 10.1016/j.molcel.2011.07.039 · DOI
- Nakamura, 2017, New insights into autophagosome-lysosome fusion, J. Cell Sci., 130, 1209, 10.1242/jcs.196352 · DOI
- Politi, 2014, Paternal mitochondrial destruction after fertilization is mediated by a common endocytic and autophagic pathway in Drosophila, Dev. Cell, 29, 305, 10.1016/j.devcel.2014.04.005 · DOI · Paper page
- Roberts, 1986, Membrane and cytoplasmic proteins are transported in the same organelle complex during nematode spermatogenesis, J. Cell Biol., 102, 1787, 10.1083/jcb.102.5.1787 · DOI
- Rodrigo-Brenni, 2010, Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin, Mol. Cell, 39, 548, 10.1016/j.molcel.2010.07.027 · DOI · Paper page
- Rual, 2004, Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library, Genome Res., 14, 2162, 10.1101/gr.2505604 · DOI
- Sato, 2017, Multiple ways to prevent transmission of paternal mitochondrial DNA for maternal inheritance in animals, J. Biochem., 162, 247
- Sato, 2011, Degradation of paternal mitochondria by fertilization-triggered autophagy in C. elegans embryos, Science, 334, 1141, 10.1126/science.1210333 · DOI
- Sato, 2018, The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans, Nat. Cell Biol., 20, 81, 10.1038/s41556-017-0008-9 · DOI · Paper page
- Scaglione, 2013, The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates, J. Biol. Chem., 288, 18784, 10.1074/jbc.C113.477596 · DOI
- Sharpley, 2012, Heteroplasmy of mouse mtDNA is genetically unstable and results in altered behavior and cognition, Cell, 151, 333, 10.1016/j.cell.2012.09.004 · DOI
- Soss, 2013, Activation of UbcH5c∼Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B, Biochemistry, 52, 2991, 10.1021/bi3015949 · DOI
- Stolz, 2011, Cdc48: a power machine in protein degradation, Trends Biochem. Sci., 36, 515, 10.1016/j.tibs.2011.06.001 · DOI
- Sutovsky, 2003, Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132, Biol. Reprod., 68, 1793, 10.1095/biolreprod.102.012799 · DOI
- Sutovsky, 1999, Ubiquitin tag for sperm mitochondria, Nature, 402, 371, 10.1038/46466 · DOI
- Sutovsky, 2000, Ubiquitinated sperm mitochondria, selective proteolysis, and the regulation of mitochondrial inheritance in mammalian embryos, Biol. Reprod., 63, 582, 10.1095/biolreprod63.2.582 · DOI
- Tatham, 2013, Ube2W conjugates ubiquitin to α-amino groups of protein N-termini, Biochem. J., 453, 137, 10.1042/BJ20130244 · DOI
- Thrower, 2000, Recognition of the polyubiquitin proteolytic signal, EMBO J., 19, 94, 10.1093/emboj/19.1.94 · DOI
- Vittal, 2013, Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimer, Cell Biochem. Biophys., 67, 103, 10.1007/s12013-013-9633-5 · DOI
- Wang, 2016, Kinetics and specificity of paternal mitochondrial elimination in Caenorhabditis elegans, Nat. Commun., 7, 12569, 10.1038/ncomms12569 · DOI
- Yoo, 2018, A molecular approach to mitophagy and mitochondrial dynamics, Mol. Cells, 41, 18
- Zhang, 2009, Together, Rpn10 and Dsk2 can serve as a polyubiquitin chain-length sensor, Mol. Cell, 36, 1018, 10.1016/j.molcel.2009.11.012 · DOI
- Zhou, 2016, Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization, Science, 353, 394, 10.1126/science.aaf4777 · DOI · Paper page
- Zhou, 2011, Elimination of paternal mitochondria through the lysosomal degradation pathway in C. elegans, Cell Res., 21, 1662, 10.1038/cr.2011.182 · DOI
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1
Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., et al. (2021) · Autophagy · doi:10.1080/15548627.2020.1797280 · Cited by 2,897
Metadata
- Authors
- Molina, P., Lim, Y., & Boyd, L.
- Venue
- Developmental Biology
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 453
- Issue
- 2
- Pages
- 168-179
- ISSN
- 0012-1606
- PMC
- PMC6685074
- Cited by
- 29
- References
- 2
- Language
- en
- Licence
- Funders
- National Institutes of Health (R15 HD083882, P40 OD010440, R01 HL127891)
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