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LAMP proteins are required for fusion of lysosomes with phagosomes

Huynh, Kassidy K, Eskelinen, Eeva‐Liisa, Scott, Cameron C, Malevanets, Anatoly, Saftig, Paul, Grinstein, Sergio·2007·The EMBO Journal

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Crossref · 10.1038/sj.emboj.7601511

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  • LAMP-1 and LAMP-2 promote coupling of lysosomes to dynein-dynactin.

    “LAMP-1 and LAMP-2 promote coupling of lysosomes to dynein–dynactin26,27”

    From TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes (2017) · cites this paper as [26]

    The Distribution and motility section reports reduced dynein-mediated lysosome transport in cells lacking LAMP-1 and LAMP-2. The Discussion proposes that LAMPs help lysosomes associate with dynein–dynactin, but says the physical link is unclear; it does not establish coupling as a demonstrated mechanism. No page numbers are available in our copy. (LLM, conf=0.86)

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Research works printed but not linked: 36

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Metadata

Authors
Huynh, K. K., Eskelinen, E., Scott, C. C., Malevanets, A., Saftig, P., & Grinstein, S.
Venue
The EMBO Journal
Published
2007-01-24
Volume
26
Issue
2
Pages
313-324
ISSN
  • 0261-4189
  • 1460-2075
Cited by
619
References
2
Language
en

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