The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Intestinal stem cells in the adult Drosophila midgut
Open accessAbstract
Drosophila has long been an excellent model organism for studying stem cell biology. Notably, studies of Drosophila’s germline stem cells have been instrumental in developing the stem cell niche concept. The recent discovery of somatic stem cells in adult Drosophila, particularly the intestinal stem cells (ISCs) of the midgut, has established Drosophila as an exciting model to study stem cell-mediated adult tissue homeostasis and regeneration. Here, we review the major signaling pathways that regulate the self-renewal, proliferation and differentiation of Drosophila ISCs, discussing how this regulation maintains midgut homeostasis and mediates regeneration of the intestinal epithelium after injury.
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Cites
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Sato, T., Vries, R. G., Snippert, H. J., van de Wetering, M., Barker, N., Stange, D. E., van Es, J. H., Abo, A., Kujala, P., Peters, P. J., et al. (2009) · Nature · doi:10.1038/nature07935 · Cited by 7,204
Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
Amado, R. G., Wolf, M., Peeters, M., Van Cutsem, E., Siena, S., Freeman, D. J., Juan, T., Sikorski, R., Suggs, S., Radinsky, R., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.14.7116 · Cited by 3,207 · cited 1×
“Most importantly, several therapies targeting EGFR have been clinically approved for colon cancer treatment, including two anti-EGFR monoclonal antibodies, Cetuximab and Panitumumab [46,47].”
BackgroundPaneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
Sato, T., van Es, J. H., Snippert, H. J., Stange, D. E., Vries, R. G., van den Born, M., Barker, N., Shroyer, N. F., van de Wetering, M., & Clevers, H. (2011) · Nature · doi:10.1038/nature09637 · Cited by 2,510
Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
Di Nicolantonio, F., Martini, M., Molinari, F., Sartore-Bianchi, A., Arena, S., Saletti, P., De Dosso, S., Mazzucchelli, L., Frattini, M., Siena, S., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2008.18.0786 · Cited by 1,591 · cited 1×
“Most importantly, several therapies targeting EGFR have been clinically approved for colon cancer treatment, including two anti-EGFR monoclonal antibodies, Cetuximab and Panitumumab [46,47].”
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Cited by
Anatomy and Physiology of the Digestive Tract of Drosophila melanogaster
Miguel-Aliaga, I., Jasper, H., & Lemaitre, B. (2018) · Genetics · doi:10.1534/genetics.118.300224 · Cited by 491
The Digestive Tract of Drosophila melanogaster
Lemaitre, B., & Miguel-Aliaga, I. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-111212-133343 · Cited by 469
A genome-wide resource for the analysis of protein localisation in Drosophila
Sarov, M., Barz, C., Jambor, H., Hein, M. Y., Schmied, C., Suchold, D., Stender, B., Janosch, S., KJ, V. V., Krishnan, R., et al. (2016) · eLife · doi:10.7554/elife.12068 · Cited by 359
Regulation and plasticity of intestinal stem cells during homeostasis and regeneration
Beumer, J., & Clevers, H. (2016) · Development · doi:10.1242/dev.133132 · Cited by 287
Physiological and stem cell compartmentalization within the Drosophila midgut
Marianes, A., & Spradling, A. C. (2013) · eLife · doi:10.7554/elife.00886 · Cited by 265
Metadata
- Authors
- Jiang, H., & Edgar, B. A.
- Venue
- Experimental Cell Research
- Publisher
- Elsevier BV
- Published
- 2011-11
- Volume
- 317
- Issue
- 19
- Pages
- 2780-2788
- ISSN
- 0014-4827 (ISSN-L)
- OpenAlex
- W1991691876
- Cited by
- 191
- References
- 4
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- green
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- Jiang, H., & Edgar, B. A. (2011). Intestinal stem cells in the adult Drosophila midgut. Experimental Cell Research. https://doi.org/10.1016/j.yexcr.2011.07.020
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
