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Cited by 174

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Estrogens, inflammation and cognition

Open access
Au, April, Feher, Anita, McPhee, Lucy, Jessa, Ailya, Oh, Soojin, Einstein, Gillian·2016·Frontiers in Neuroendocrinology
DOI 10.1016/j.yfrne.2016.01.002
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Abstract

The effects of estrogens are pleiotropic, affecting multiple bodily systems. Changes from the body's natural fluctuating levels of estrogens, through surgical removal of the ovaries, natural menopause, or the administration of exogenous estrogens to menopausal women have been independently linked to an altered immune profile, and changes to cognitive processes. Here, we propose that inflammation may mediate the relationship between low levels of estrogens and cognitive decline. In order to determine what is known about this connection, we review the literature on the cognitive effects of decreased estrogens due to oophorectomy or natural menopause, decreased estrogens' role on inflammation--both peripherally and in the brain--and the relationship between inflammation and cognition. While this review demonstrates that much is unknown about the intersection between estrogens, cognition, inflammation, we propose that there is an important interaction between these literatures.

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Metadata

Authors
Au, A., Feher, A., McPhee, L., Jessa, A., Oh, S., & Einstein, G.
Venue
Frontiers in Neuroendocrinology
Publisher
Elsevier BV
Published
2016-01
Volume
40
Pages
87-100
ISSN
0091-3022 (ISSN-L)
DOI
10.1016/j.yfrne.2016.01.002
OpenAlex
W2238869079
Cited by
174
References
32
FWCI
15.88
Type
journal article
Language
en
Open access
hybrid

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.