The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Plasticizer endocrine disruption: Highlighting developmental and reproductive effects in mammals and non-mammalian aquatic species
Open accessAbstract
Due to their versatility, robustness, and low production costs, plastics are used in a wide variety of applications. Plasticizers are mixed with polymers to increase flexibility of plastics. However, plasticizers are not covalently bound to plastics, and thus leach from products into the environment. Several studies have reported that two common plasticizers, bisphenol A (BPA) and phthalates, induce adverse health effects in vertebrates; however few studies have addressed their toxicity to non-mammalian species. The aim of this review is to compare the effects of plasticizers in animals, with a focus on aquatic species. In summary, we identified three main chains of events that occur in animals exposed to BPA and phthalates. Firstly, plasticizers affect development by altering both the thyroid hormone and growth hormone axes. Secondly, these chemicals interfere with reproduction by decreasing cholesterol transport through the mitochondrial membrane, leading to reduced steroidogenesis. Lastly, exposure to plasticizers leads to the activation of peroxisome proliferator-activated receptors, the increase of fatty acid oxidation, and the reduction in the ability to cope with the augmented oxidative stress leading to reproductive organ malformations, reproductive defects, and decreased fertility.
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Neuroendocrine pharmacology of stress
Carrasco, G. A., & Van de Kar, L. D. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01285-8 · Cited by 914
Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist
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Levels of Seven Urinary Phthalate Metabolites in a Human Reference Population
Blount, B. C., Silva, M. J., Caudill, S. P., Needham, L. L., Pirkle, J. L., Sampson, E. J., Lucier, G. W., Jackson, R. J., & Brock, J. W. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108979 · Cited by 634
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Cited by
Current applications of poly(lactic acid) composites in tissue engineering and drug delivery
Liu, S., Qin, S., He, M., Zhou, D., Qin, Q., & Wang, H. (2020) · Composites Part B: Engineering · doi:10.1016/j.compositesb.2020.108238 · Cited by 533
Alfaro-Núñez, A., Astorga, D., Cáceres-Farías, L., Bastidas, L., Soto Villegas, C., Macay, K., & Christensen, J. H. (2021) · Scientific Reports · doi:10.1038/s41598-021-85939-3 · Cited by 309
Impact of chemical endocrine disruptors and hormone modulators on the endocrine system
Guarnotta, V., Amodei, R., Frasca, F., Aversa, A., & Giordano, C. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105710 · Cited by 171
Mofijur, M., Ahmed, S. F., Rahman, S. M. A., Arafat Siddiki, S. Y., Islam, A. B. M. S., Shahabuddin, M., Ong, H. C., Mahlia, T. M. I., Djavanroodi, F., & Show, P. L. (2021) · Environmental Research · doi:10.1016/j.envres.2021.110857 · Cited by 172
Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement
Bennett, D., Bellinger, D. C., Birnbaum, L. S., DABT, A.T.S, Bradman, A., Chen, A., Cory-Slechta, D. A., Engel, S. M., Fallin, M. D., et al. (2016) · Environmental Health Perspectives · doi:10.1289/ehp358 · Cited by 169
Metadata
- Authors
- Mathieu-Denoncourt, J., Wallace, S. J., de Solla, S. R., & Langlois, V. S.
- Venue
- General and Comparative Endocrinology
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 219
- Pages
- 74-88
- ISSN
- 0016-6480 (ISSN-L)
- OpenAlex
- W1970121614
- Cited by
- 307
- References
- 6
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Mathieu-Denoncourt, J., Wallace, S. J., de Solla, S. R., & Langlois, V. S. (2015). Plasticizer endocrine disruption: Highlighting developmental and reproductive effects in mammals and non-mammalian aquatic species. General and Comparative Endocrinology. https://doi.org/10.1016/j.ygcen.2014.11.003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
