The DOI matches its Crossref record; 161 of the 161 references it cites were found in a registry or an index.
Sexual differentiation of motivation: A novel mechanism?
Open accessAbstract
Sex differences in motivation are apparent for the motivation to engage in sexual behavior, the motivation to take drugs of abuse, and the motivation to engage in parental behavior. In both males and females there is an increase in NAcc DA associated with motivated behaviors. Here it proposed that sex differences in the regulation of DA activity in the ascending mesolimbic projections may underlie sex differences in motivation. In particular, sex differences in the neuroendocrine regulation of this brain system play a role in the expression of sex differences in motivated behaviors. Here it is proposed that sexual differentiation of motivation is mediated, at least in part, by a novel mechanism in which ovarian hormones secreted at puberty in the female actively feminize the DA system.
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“several rodent studies point to effects of pubertal estradiol and testosterone on dopaminergic function (reviewed in Becker, 2009; Kuhn et al., 2010; Sinclair et al., 2014).”
From Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017) · cites this paper as Becker, 2009
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“Thus, although scant, literature on the effects of pubertal hormones on the development of the dopamine system suggests that some aspects of dopaminergic function respond to pubertal increases in circulating gonadal hormones.”
From Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017) · cites this paper as Becker, 2009
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Research works printed but not linked: 5
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- Becker, 2007, Neurochemistry and molecular biology of reward, Vol. 21, 739
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Metadata
- Authors
- Becker, J. B.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Becker, Jill B.
- ORCID
- Becker, Jill B.
- Venue
- Hormones and Behavior
- Publisher
- Elsevier BV
- Published
- 2009-05
- Volume
- 55
- Issue
- 5
- Pages
- 646-654
- ISSN
- 0018-506X (ISSN-L)
- PMC
- PMC2684520
- OpenAlex
- W2018825306
- Cited by
- 115
- References
- 160
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 4 · 2022: 3 · 2021: 5 · 2020: 5 · 2019: 7 · 2018: 9 · 2017: 8 · 2016: 8 · 2015: 8 · 2014: 9 · 2013: 19 · 2012: 10
- FWCI
- 3.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Hormones and Behavior (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (DA12677, R01DA012677)
- National Institute of Neurological Disorders and Stroke (NS048141, R01NS048141)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Keywords
- dopamine, nucleus accumbens, mesolimbic dopamine system, ovarian hormones, puberty, sexual differentiation, sexual behavior, parental behavior, neuroendocrine regulation
- MeSH terms
- Animals, Behavior, Brain, Dopamine, Female, Humans, Male, Maternal Behavior, Motivation, Reward, Sexual Behavior, Sex Characteristics, Sex Differentiation, Sex Factors, Gonadal Steroid Hormones, Behavior, Addictive
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