Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain.
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The LS is associated with electrical self-stimulation in rats and humans.
“the LS is associated with electrical self-stimulation in rats and humans [34,35]”
From Involvement of dopamine, but not norepinephrine, in the sex-specific regulation of juvenile socially rewarding behavior by vasopressin (2018) · cites this paper as [34]
The LS is part of the brain reward system.
“other studies indicating that the LS is part of the brain reward system.”
From Involvement of dopamine, but not norepinephrine, in the sex-specific regulation of juvenile socially rewarding behavior by vasopressin (2018) · cites this paper as [34]
Rats persistently and repeatedly chose to stimulate the VTA mesolimbic DA pathway but not other brain areas, often to the exclusion of other behaviors.
“The rats persistently and repeatedly chose to stimulate the VTA mesolimbic DA pathway (but not other brain areas), often to the exclusion of other behaviors.”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [54]
Dopamine neurotransmission is strongly implicated in the reinforcement of self-administering drugs or electrical stimulation in animals.
“Dopamine neurotransmission is strongly implicated in the reinforcement of self-administering drugs or electrical stimulation in animals.”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [54]
1960s studies of reward and hunger motivation caused by brain electrode stimulation moved motivation theory away from negative drive theories to positive incentive theories of motivation.
“Perhaps the single most compelling piece of evidence that moved motivation theory away from negative drive theories to positive incentive theories of motivation came from 1960s studies of reward and hunger motivation caused by brain electrode stimulation – mostly at sites in the lateral hypothalamus that indirectly also activated mesolimbic dopamine systems (Olds and Milner, 1954; Valenstein et al”
From Evolving Concepts of Emotion and Motivation (2018) · cites this paper as Olds and Milner, 1954
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- Authors
- Olds, J., & Milner, P.
- Affiliations
- McGill University (CA)
- Venue
- Journal of Comparative and Physiological Psychology
- Published
- 1954
- Volume
- 47
- Issue
- 6
- Pages
- 419-427
- ISSN
- 0021-9940 (ISSN-L)
- OpenAlex
- W2025440394
- Cited by
- 3,176
- References
- 13
- Citations by year
- 2026: 34 · 2025: 71 · 2024: 116 · 2023: 102 · 2022: 95 · 2021: 81 · 2020: 157 · 2019: 151 · 2018: 125 · 2017: 95 · 2016: 112 · 2015: 105 · 2014: 105 · 2013: 109 · 2012: 106
- FWCI
- 13.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Comparative and Physiological Psychology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- positive reinforcement, electrical brain stimulation, septal area, septal nuclei, reward, rat brain, operant conditioning
- MeSH terms
- Animals, Brain, Cerebral Ventricles, Electric Stimulation, Learning, Reinforcement, Psychology, Septum of Brain, Rats
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