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Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice
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“sEVs from IL-4 or IL-13-stimulated microglia, also referred to as M2 microglia-derived sEVs (M2-sEVs), demonstrated neuroprotective functions by modulating various cell fates across multiple CNS diseases [19, 20].”
From M2 microglia-derived small extracellular vesicles modulate NSC fate after ischemic stroke via miR-25-3p/miR-93-5p-TGFBR/PTEN/FOXO3 axis (2025) · cites this paper as [19]
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The chemokine system in diverse forms of macrophage activation and polarization
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Neuroinflammation and M2 Microglia: The Good, the Bad, and the Inflamed
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Greenhalgh, A. D., & David, S. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.4912-13.2014 · Cited by 296
GM‐CSF promotes proliferation of human fetal and adult microglia in primary cultures
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Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation
Cherry, J. D., Olschowka, J. A., & O’Banion, M. K. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0411-8 · Cited by 152
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Metadata
- Authors
- Kobashi, S., Terashima, T., Katagi, M., Nakae, Y., Okano, J., Suzuki, Y., Urushitani, M., & Kojima, H.
- Venue
- Molecular Therapy
- Publisher
- Elsevier BV
- Published
- 2020-01
- Volume
- 28
- Issue
- 1
- Pages
- 254-265
- ISSN
- 1525-0016
- Cited by
- 186
- References
- 7
- Language
- en
- Licence
- Funders
- Ministry of Education, Culture, Sports, Science and Technology
- KAKENHI (JP17H04358, JP18K07498)
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- Kobashi, S., Terashima, T., Katagi, M., Nakae, Y., Okano, J., Suzuki, Y., Urushitani, M., & Kojima, H. (2020). Transplantation of M2-Deviated Microglia Promotes Recovery of Motor Function after Spinal Cord Injury in Mice. Molecular Therapy. https://doi.org/10.1016/j.ymthe.2019.09.004