Cited by 148Lipoproteins and Cardiovascular HealthPhysical Activity and HealthCardiovascular and exercise physiology

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Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials

Kelley, G·2004·Preventive Medicine

DOI 10.1016/j.ypmed.2003.12.012

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Abstract

Background The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults.Methods Randomized controlled trials that examined the effects of walking on total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), the ratio of TC/HDL, and triglycerides (TG) in adults ages 18 years and older were retrieved via computerized literature searches, cross-referencing, hand-searching, and expert review of our reference list.Results Twenty-five studies that included 1,176 subjects (692 walkers, 484 controls) and up to 33 outcomes were available for pooling. Using random-effects modeling, statistically significant, walking-induced decreases of 5% and 6% were observed for LDL-C and TC/HDL-C (LDL-C, mean +/- SE, -5.5 +/- 2.2 mg/dL, 95% CI, -9.9 to -1.2 mg/dL; TC/HDL-C, mean +/- SE, -0.3 +/- 0.1, 95% CI, -0.6 to -0.1). No statistically significant changes were observed for TC, HDL, or TG (P > 0.05), although changes were in the direction of benefit. No statistically significant changes occurred in body composition (P > 0.05).Conclusions Walking reduces LDL-C and TC/HDL-C in adults independent of changes in body composition.

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Authors: Kelley, G.
Affiliations: West Virginia University (US)
Corresponding author: Kelley, G
ORCID: Kelley, G
Venue: Preventive Medicine
Publisher: Elsevier BV
Published: 2004-05
Volume: 38
Issue: 5
Pages: 651-661
ISSN: 0091-7435 (ISSN-L)
DOI: 10.1016/j.ypmed.2003.12.012
OpenAlex: W2040589021
Cited by: 148
References: 47
Citations by year: 2025: 3 · 2024: 4 · 2023: 7 · 2022: 4 · 2021: 1 · 2020: 7 · 2019: 7 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 8 · 2014: 6 · 2013: 12 · 2012: 10
FWCI: 1.70
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Preventive Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Heart, Lung, and Blood Institute (R01HL069802)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Keywords: walking, physical activity, lipids, lipoproteins, LDL cholesterol, total cholesterol, HDL cholesterol, triglycerides, TC/HDL-C ratio, body composition, cardiovascular risk factors
MeSH terms: Adult, Cholesterol, Female, Humans, Lipoproteins, Male, Middle Aged, Triglycerides, Randomized Controlled Trials as Topic, Walking

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Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials

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